Search clinical trials for: Inhaled leukotriene E4

Total 1399 results

Karolinska University Hospital
Karolinska Institutet

Unknown

A Mechanistic Study to Evaluate the Efficacy of Montelukast on Airway Function in Asthma (E-Type)

Asthma

Sweden
NEURALIS s.a.

Recruiting

Single and Multiple Intravenous Administrations of Estetrol (E4) in Healthy Adult Volunteers

Pharmacokinetics | Safety

Bulgaria
Columbia University

Terminated

Detection of Gastrointestinal Bleeding in Intensive Care Patients Via Biosensor Watch

Gastro Intestinal Bleeding

United States
Estetra
Quotient Clinical

Completed

Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrol

Menopause | Contraception

United Kingdom
Estetra

Completed

Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers

Menopause | Contraception

Bulgaria
Donesta Bioscience

Completed

Effect of Food on the Bioavailability of 30 mg Estetrol (E4) Tablet in Healthy Postmenopausal Female Volunteers

Food-effect

Bulgaria
Donesta Bioscience
SynteractHCR

Completed

E4Relief (Response to Estetrol in Life Improvement for MEnopausal-associated Hot Flushes)

Hot Flushes

Belgium
Mayo Clinic

Enrolling by invitation

Development of a Practical, Minimally Invasive Seizure Gauge

Epilepsy

United States
Seer Medical Pty Ltd

Enrolling by invitation

Development of a Minimally Invasive Seizure Gauge

Epilepsy

Australia
Estetra
ICON Clinical Research

Completed

Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort)

Vasomotor Symptoms | Menopausal Symptoms

United States, Canada
Estetra

Recruiting

Estetrol for the Treatment of Female Sexual Arousal Disorder in Postmenopausal Women

Sexual Dysfunction, Physiological

United States
Orion Corporation, Orion Pharma

Completed

Inspiratory Flow Parameters and Handling of Easyhaler and Turbuhaler Inhalers (PIFECO)

Pulmonary Disease, Chronic Obstructive | Asthma

United Kingdom, Finland
Zeno Pharmaceuticals, Inc.

Completed

A Study of ZN-e4 in Subjects With Epidermal Growth Factor Receptor Mutated Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Bosnia and Herzegovina
NEURALIS s.a.

Active, not recruiting

Estetrol (E4) for the Treatment of Patients With Confirmed SARS-COV-2 Infection

Covid19

Belgium, Hungary, Russian Federation, Poland
Synspira, Inc.

Terminated

A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis

Lung Diseases | Cystic Fibrosis | Pulmonary Disease | Antibiotic Resistant Infection | Respiratory Tract Disease | Cystic Fibrosis Pulmonary Exacerbation | Lung Inflammation | Burkholderia Infections | Lung Infection | Multi-antibiotic Resistance | Pulmonary Inflammation | Lung Infection Pseudomonal | Cystic Fibrosis... and other conditions

United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust

Unknown

The CEDiD Study (COVID-19 Early Diagnosis in Doctors and Healthcare Workers) (CEDiD)

Covid19

United Kingdom
GlaxoSmithKline

Completed

Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment

Pulmonary Disease, Chronic Obstructive

Czechia, Hungary
GlaxoSmithKline

Completed

A Study to Assess the Effects of GSK573719/VI Combination and GSK573719 Monotherapy in Subjects With Moderate Hepatic Impairment and Matched Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

Hungary, Slovakia
Galecto Biotech AB

Completed

RCT (Randomized Control Trial) of TD139 vs Placebo in HV's (Human Volunteers) and IPF Patients

Idiopathic Pulmonary Fibrosis

United Kingdom
Makerere University
University of Copenhagen

Completed

Inhaled Corticosteroids in U-5 Children With Acute Respiratory Infection in Uganda: A Randomised Trial (ICS)

Bacterial Pneumonia | Acute Asthma | Viral Pneumonia

Uganda
Estetra

Completed

E4/DRSP Single and Multiple Dose PK and Early QT Study

Contraception
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK2339345.

Cough

United Kingdom
Imperial College London

Completed

Measuring Hydrogen Peroxide in Exhaled Breath Condensate in HV

Proof Of Concept Study

United Kingdom
Boehringer Ingelheim

Completed

The OPTI Study in Spain Looks at the History Flare-ups in Patients With Chronic Obstructive Pulmonary Disease (COPD) Treated With Inhaled Steroids.

Pulmonary Disease, Chronic Obstructive

Spain
Liquidia Technologies, Inc.
Nuventra, Inc.

Completed

Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil (INSPIRE)

Primary Pulmonary Hypertension

United States
Pearl Therapeutics, Inc.

Completed

Phase I Study Evaluating the Safety and Pharmacokinetics of Budesonide, Glycopyrronium, and Formoterol Fumarate Inhalation Aerosol (BGF MDI) in Healthy Volunteers

Healthy Volunteers

United States
Liquidia Technologies, Inc.
Nuventra, Inc.

Active, not recruiting

Extension Study for Participants in LIQ861 Trials to Evaluate the Long-term Safety of Dry Powder Inhalation of Treprostinil

Primary Pulmonary Hypertension

United States
National Heart, Lung, and Blood Institute (NHLBI)
Childhood Asthma Research and Education Network

Completed

Prevention of Early Asthma in Kids (PEAK)

Lung Diseases | Asthma
Alexza Pharmaceuticals, Inc.

Completed

Staccato Prochlorperazine in Migraine (Out Patient)

Migraine Headache | Aura

United States
Ajou University School of Medicine
AstraZeneca

Recruiting

Long-term Effect of Steroid on Metabolic Diseases in Asthmatics

Asthma | Osteoporosis Risk | Osteoporotic Fractures | Osteoporosis, Osteopenia

Korea, Republic of
GlaxoSmithKline

Completed

WEUKBRE5554: IMI PROTECT(Work Package 2): Beta2 Agonists and Acute Myocardial Infarction

Asthma
Massachusetts General Hospital
Rezoagli, Emanuele, M.D., Massachusetts General Hospital, Harvard Medical... and other collaborators

Active, not recruiting

Prolonged Hypoxic Breathing in Healthy Volunteers: a Safety Study (MGH-nitrogen)

Healthy Volunteers

United States
Second Affiliated Hospital, School of Medicine,...

Unknown

Clinical Characteristics and Treatment of Chest Tightness Variant Asthma

Quality of Life | Asthma | Eosinophilia | Nitric Oxide | Airway Responsiveness | Clinical Depression | Chest Syndrome | Lung Function | Clinical Anxiety | Induced Sputum

China
Aridis Pharmaceuticals, Inc.

Recruiting

SAD and MAD of Inhaled AR-501 in Health Adults and P. Aeruginosa Infected Cystic Fibrosis Subjects

Cystic Fibrosis

United States
Washington University School of Medicine
Barnes-Jewish Hospital

Completed

Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity (Peri-Op)

Surgical Wound Infection | Endometritis | Infection; Cesarean Section

United States
Liquidia Technologies, Inc.
FGK Clinical Research GmbH

Terminated

Hemodynamic Evaluation of Dose-response and Safety of Dry Powder Inhalation of Treprostinil

Pulmonary Arterial Hypertension

France, Germany
Parc de Salut Mar

Active, not recruiting

Asthma Research in Children and Adolescents (ARCA)

Asthma in Children | Persistent Asthma | Asthma Exacerbation

Spain
ISBRG Corp
National Advanced Driving Simulator

Recruiting

Detection of Cannabis Impairment With ISBRG's SpotLight-THC

Cannabis

United States
Novartis

Completed

A Study to Assess the Efficacy of Inhaled Corticosteroid (ICS) Therapy in Moderate-Severe Bronchial Asthma

Bronchial Asthma

Germany
Scott and White Hospital & Clinic
Anodyne Therapy, LLC

Completed

Anodyne Therapy in Diabetic Sensory Neuropathy

Diabetes Mellitus | Diabetic Neuropathy

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of Dust Mite Inhalation in Humans

Allergy | Mild Asthma

United States
Children's National Research Institute

Completed

Improving Pediatric Asthma Care Through Inhaled Steroids in Schools (ISIS)

Asthma
University of Toronto
University Health Network, Toronto; Thornhill Research

Unknown

The Response of Intraocular Pressure to Systemic Hypercapnia and Hyperoxia

Intraocular Pressure

Canada
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Childhood Asthma Research and Education (CARE) Network Trial - Acute Intervention Management Strategies (AIMS) (AIMS)

Lung Diseases | Asthma

United States
Alexza Pharmaceuticals, Inc.

Completed

Staccato Loxapine Single Dose PK

Schizophrenia

United States
Mental Health Services in the Capital Region, Denmark
University of Copenhagen; Technical University of Denmark

Recruiting

A Wearable AI Feedback Tool for Pediatric OCD

Obsessive-Compulsive Disorder

Denmark
Yonsei University

Not yet recruiting

Effects of Iloprost on Oxygenation During One-lung Ventilation in Supine-positioned Patients

Mediastinal Mass

Korea, Republic of
Alexza Pharmaceuticals, Inc.

Completed

Staccato Fentanyl Single and Multidose PK

Breakthrough Pain

United States
University Hospital, Tours

Completed

Study Comparing Inhaled Amikacin Versus Placebo to Prevent Ventilator Associated Pneumonia (AMIKINHAL)

Pneumonia, Ventilator-Associated

France
Estetra
Quotient Sciences

Completed

Estetrol (E4)/Drospirenone (DRSP) Drug-drug Interaction (DDI) Study

Contraception

United Kingdom

Search clinical trials for: Inhaled leukotriene E4

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