Search clinical trials for: Intranasal naloxone

Total 745 results

Wake Forest University Health Sciences

Withdrawn

Long Acting Buprenorphine Injection Compared to Sublingual Buprenorphine/Naloxone Films

Opioid Use
Indivior Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Depot Buprenorphine at Three Different Molecular Weights in Treatment-Seeking Subjects With Opioid Use Disorder

Opioid Use Disorder

United States
OptiNose AS
University of Oslo

Completed

Effects of Intranasal Administration of a Single Dose of Oxytocin Using a Novel Device in Healthy Adults

Healthy Male Adults

Norway
Shalvata Mental Health Center

Recruiting

Intranasal Oxytocin as Enhancer of Psychotherapy Outcomes in Severe Mental Illness

Severe Mental Illness

Israel
Opiant Pharmaceuticals Inc

Completed

Pharmacodynamic Evaluation of Intranasal Nalmefene

Pharmacodynamic

United States
Mario Negri Institute for Pharmacological Research

Completed

GREAT - Good Response With Appropriate Treatment

Neoplasms | Cancer Pain

Italy
Tiziana Life Sciences LTD

Withdrawn

Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS

Multiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis
Lifespan
University of Rhode Island

Completed

Medication Maintenance Therapy in Community Pharmacy Settings (MATPharm)

Opioid-use Disorder

United States
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) - Year 1, 2009

Influenza

United States
University of Chicago
Community Outreach Intervention Projects; Cook County Sheriff Office; Cook County... and other collaborators

Recruiting

Reducing Opioid Mortality in Illinois (ROMI)

Opioid Use | Opioid-use Disorder

United States
Develco Pharma Schweiz AG

Unknown

Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation (Naxos)

Opioid-Induced Constipation

United Kingdom, Bulgaria, Czechia, Germany, Poland, Portugal, Serbia, Slovakia, Spain
Levo Therapeutics, Inc.

Completed

Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome (CARE-PWS)

Prader-Willi Syndrome

United States, Canada, Australia
HealthPartners Institute
Juvenile Diabetes Research Foundation; International Diabetes Center at Park...

Terminated

IN Insulin in Type 1 Diabetes (T1D) Hypoglycemia Unawareness: Safety Only Phase

Type1diabetes

United States
University of California, Los Angeles

Completed

Oxytocin and the Social Brain

Social Psychology

United States
Javelin Pharmaceuticals

Completed

Efficacy and Safety of Intranasal Morphine for Pain After Third Molar Extraction

Post-Operative Pain | Third Molar Extraction
Rigshospitalet, Denmark
National Institute on Drug Abuse (NIDA); University of Kentucky

Completed

Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.

Pain | Hyperalgesia | Central Nervous System Sensitization

Denmark
Elorac, Inc.

Terminated

Naloxone Hydrochloride Study for Relief of Pruritus in Patients With MF or SS Forms of CTCL

Lymphoma, T-Cell, Cutaneous | Mycosis Fungoides | Sézary Syndrome

United States
Mahidol University

Completed

Efficacy of Intramuscular Naloxone 0.4mg. in Prophylaxis of Intrathecal Morphine Induced Pruritus After Cesarean Section

Morphine Adverse Reaction

Thailand
Region Skane

Active, not recruiting

Naloxone Treatment in Skåne County - Effect on Drug-related Mortality and Overdose-related Complications

Opioid Abuse

Sweden
Seema Capoor

Completed

Topical Naloxone to Diagnose Ocular Pain

Dry Eye Syndromes | Neuropathic Pain

United States
Ullevaal University Hospital
Mundipharma AB

Completed

A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy

Postoperative Pain | Opioid Induced Constipation

Norway
BioDelivery Sciences International

Withdrawn

Evaluation of BEMA® Buprenorphine NX for Buprenorphine Induction of Opioid Dependent Subjects

Opioid Dependence

United States
US Department of Veterans Affairs
National Institute on Drug Abuse (NIDA); Reckitt and Colman

Completed

Determine the Safety of a Sublingual Tablet Formulation of Buprenorphine and Naloxone by Extending the Combination Tablet Availability to Physicians in Office-Based Practice

Opiate Dependence

United States
University of Colorado, Denver
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Not yet recruiting

Clinical Decision Support to Improve System Naloxone Co-prescribing

Harm Reduction | Medication Abuse

United States
Mansoura University

Completed

Effect of Ultra-low Dose Naloxone During Supraclavicular Brachial Plexus Block on Post-operative Opioi

Upper Extremity Trauma

Egypt
University of Florida
University of Arizona; McKnight Brain Research Foundation

Recruiting

Pilot Intervention With Near Infrared Stimulation

Parkinson Disease | Aging

United States
Didier Jutras Aswad
Canadian Institutes of Health Research (CIHR)

Completed

A Pragmatic Randomized Control Trial Comparing Models of Care in the Management of Prescription Opioid Misuse (OPTIMA)

Opioid Use Disorder

Canada
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Effects of a Kappa Agonist on Hot Flashes in Menopausal Women

Treatment of Menopausal Hot Flashes

United States
State University of New York at Buffalo
National Institute on Drug Abuse (NIDA); National Institute on Alcohol Abuse...

Completed

Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients

Opiate Addiction

United States
Astellas Pharma Global Development, Inc.
National Institute on Drug Abuse (NIDA)

Completed

A Study to Assess the Effect of a Single Dose of ASP8062 on the Multiple Dose Safety, Tolerability and Pharmacokinetics of Buprenorphine/Naloxone in Participants With Opioid Use Disorder

Opioid Use Disorder

United States
Mundipharma Research GmbH & Co KG

Completed

A Study Comparing Oxycodone to Oxycodone/Naloxone in Moderate to Severe, Chronic Cancer Pain

Pain | Cancer | Constipation

United Kingdom
Assiut University

Completed

a Small Dose of Naloxone,Minimize Intrathecal Morphine Side Effects

Post-Op Complication

Egypt
Kuopio University Hospital

Completed

Opioid Induced Bowel Dysfunction in Patients Undergoing Spinal Surgery (oksineukir)

Constipation

Finland
Meissa Vaccines, Inc.

Recruiting

Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults

Covid19

United States
University Hospital, Clermont-Ferrand

Completed

Impact of Naloxone on the Analgesic Effect of Paracetamol in Healthy Volunteers

Pain

France
Pfizer

Completed

Acute Treatment Trial in Adult Subjects With Migraines

Migraine

United States
Mundipharma Korea Ltd

Completed

An Interventional Study to Compare the Efficacy and Tolerability With Targin® in Non-malignant Chronic Pain (GLORY)

Chronic Pain

Korea, Republic of
Norwegian University of Science and Technology
St. Olavs Hospital; Lade Addiction Treatment Center

Completed

Intranasal Oxytocin Effects in Alcohol Withdrawal and Dependence; Follow-up Study

Substance-Related Disorders | Alcoholism

Norway
Norwegian University of Science and Technology
St. Olavs Hospital; Lade Addiction Treatment Center

Completed

Oxytocin and Alcohol Withdrawal and Dependence

Substance-Related Disorders | Alcoholism

Norway
University of North Carolina, Chapel Hill

Completed

Oxytocin Treatment of Alcohol Dependence (OT-ETOH2)

Alcohol Dependence | Alcohol Withdrawal
University of California, Los Angeles
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Cocaine Use Reduction With Buprenorphine (CURB)

Cocaine Dependence

United States
State University of New York at Buffalo

Completed

Buprenorphine and Methadone for Opioid-dependent Chronic Back Pain Patients

Low Back Pain

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Pharmacokinetic Effect of SCH 503034 (Boceprevir) on Methadone or Buprenorphine/Naloxone Plasma Concentrations (P08123)

Hepatitis C Virus
Mundipharma Pharmaceuticals B.V.

Completed

Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain

Pain

Belgium
Mundipharma (China) Pharmaceutical Co. Ltd

Completed

Targin for Non-cancer Pain

Non Cancer Pain

China
Lifespan
The Miriam Hospital; University of Rhode Island

Active, not recruiting

Medication Maintenance Therapy in Community Pharmacy Settings (MATPharm)

Opioid-use Disorder

United States
Astellas Pharma Global Development, Inc.

Withdrawn

A Study to Assess the Safety and Efficacy of ASP8062 as an Add-on Therapy to Buprenorphine/Naloxone in Participants With Opioid Use Disorder

Opioid Use Disorder
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine Naltrexone-P1 A-Cocaine

Cocaine-related Disorders

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

HIV Risk Reduction in Subutex Injectors in Tbilisi

HIV

Georgia
Paolo Mannelli
Alkermes, Inc.

Completed

Low Dose Naltrexone-buprenorphine Transfer to Vivitrol Injection in Opioid Dependence (BUP/NXT-VIVI)

Opiate Dependence

United States

Search clinical trials for: Intranasal naloxone

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