Search clinical trials for: Intravenous Tenecteplase

Total 6517 results

The George Institute
University of Calgary; Berry Consultants

Not yet recruiting

ACT-GLOBAL Adaptive Platform Trial for Stroke (ACT-GLOBAL)

Stroke
Hospital Moinhos de Vento
Boehringer Ingelheim; Ministry of Health, Brazil; Brainomix Limited; iSchemaView...

Recruiting

Randomization to Extend Stroke Intravenous ThromboLysis In Evolving Non-Large Vessel Occlusion With TNK (RESILIENT (EXTEND-IV)

Ischemic Stroke, Acute

Brazil
The First Affiliated Hospital of University of...

Recruiting

Endovascular Thrombectomy Alone Versus Intravenous Thrombolysis Plus Thrombectomy on Acute Basilar Artery Occlusion

Basilar Artery Occlusion | Acute Cerebrovascular Accident | Stroke Due to Basilar Artery Occlusion

China
NHS Greater Glasgow and Clyde
University of Edinburgh; Oxford University Hospitals NHS Trust; University of...

Completed

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST2)

Ischemic Stroke

United Kingdom
Kaiser Permanente
Genentech, Inc.

Terminated

Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy

Pleural Effusion

United States
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai East Hospital; The Second Affiliated... and other collaborators

Completed

CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase (CHABLIS-T)

Stroke

China
Boehringer Ingelheim

Terminated

Thrombolysis Using Tenecteplase (Metalyse®) in Cardiac Arrest - The TROICA Trial

Heart Arrest

Germany, Belgium, Sweden, France, Austria, Italy, Norway, Spain, Switzerland
Genentech, Inc.

Completed

A Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters (TROPICS 2)

Dysfunctional Central Venous Access Catheters
University Of Perugia

Terminated

Tenecteplase Pulmonary Embolism Italian Study

Pulmonary Embolism

Italy
Genentech, Inc.

Completed

A Study of Tenecteplase for Restoration of Function in Dysfunctional Hemodialysis Catheters (TROPICS 3)

Dysfunctional Hemodialysis Catheters
Genentech, Inc.

Completed

A Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters (TROPICS 1)

Dysfunctional Central Venous Access Catheters
Second Affiliated Hospital of Guangxi Medical University
CSPC Pharmaceutical Group Limited

Not yet recruiting

Early Administration of Tirofiban in Patients Treated With Tenecteplase for Acute Ischemic Stroke (ATTIS)

Acute Ischemic Stroke
General Hospital of Shenyang Military Region

Completed

Boosting REcanalization of Thrombectomy for Ischemic Stroke by Intra-arterial TNK (BRETIS-TNK)

Ischemic Stroke

China
ProMedica Health System
Genentech, Inc.

Completed

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial (ALLY)

Ischemic Stroke

United States
First Hospital of China Medical University

Not yet recruiting

Additive Effects of Intra-arterial Tenecteplase for Successful Thrombectomy Due to Acute Basilar Artery Occlusion

Basilar Artery Occlusion | Thrombectomy | Tenecteplase
Hui-Sheng Chen

Recruiting

Improving Neuroprotective Strategy for Ischemic Stroke With Poor Recanalization After Thrombectomy by Intra-arterial TNK (INSIST-TNK)

Ischemic Stroke

China
University of Melbourne

Recruiting

Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke (POST-ETERNAL)

Basilar Artery Occlusion

Australia
University of Melbourne
Professor Mark Parsons

Recruiting

Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion (ETERNAL-LVO)

Ischemic Stroke

Australia
Boehringer Ingelheim

Completed

A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity (ORIGINAL)

Stroke

China
University Hospital Center of Martinique

Withdrawn

Superiority of Rt-PA + Tenecteplase in Comparison With Rt-PA Only in Proximal Middle Cerebral Artery Occlusion (DIVA)

Nervous System Disorders | Cerebral Artery
Assistance Publique - Hôpitaux de Paris
Boehringer Ingelheim; German Federal Ministry of Education and Research

Completed

PEITHO Pulmonary Embolism Thrombolysis Study (PEITHO)

Pulmonary Embolism

Israel, Poland, Portugal, Spain, Austria, Belgium, France, Germany, Greece, Hungary, Italy, Slovenia
University of Alberta

Completed

Penumbral Based Novel Thrombolytic Therapy in Acute Ischemic Stroke (TIAS)

Stroke | Brain Ischemia | Cerebral Infarction

Canada
Centre Hospitalier Sud Francilien

Recruiting

Early Recanalization After Intravenous Thrombolysis With Tenecteplase Versus Alteplase in Distal Vessel Occlusion Strokes (DISTAL-IVT)

Acute Distal Vessel Occlusion Stroke

France
Centre Hospitalier Sud Francilien

Completed

Tirofiban Plus Intravenous Thrombolysis in Acute Anterior Choroidal Infarction or Paramedian Pontine Infarction (TITACIPPI)

Acute Anterior Choroidal Infarction (ACI) | Paramedian Pontine Infarction (IPP)

France
Centre Hospitalier Sud Francilien

Completed

Dual IntraVenous Thrombolysis Approach (DIVA) in Patients With Medium-vessel-occlusion Strokes: a Retrospective Study (DIVArétro)

Acute Ischemic Stroke Due to Medium-vessel-occlusion

France
University of Melbourne

Not yet recruiting

Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke

Cerebrovascular Disorders | Central Nervous System Diseases | Ischemic Stroke, Acute | Brain Disorder

Australia
Wake Forest University Health Sciences

Terminated

Clot Dissolving Treatment for Blood Clots in the Lungs

Pulmonary Embolism

United States
Chinese University of Hong Kong
Queen Mary Hospital, Hong Kong; Princess Margaret Hospital, Canada; Tuen Mun... and other collaborators

Not yet recruiting

Intravenous Thrombolytic Therapy in Acute Ischemic Stroke Patients on DOAC (DOAC-IVT)

CVA (Cerebrovascular Accident)

Hong Kong
Boehringer Ingelheim

Completed

A Trial on Efficacy and Safety of Full Dose Tenecteplase Combined With Unfractionated Heparin (UFH) or Enoxaparin in Acute Myocardial Infarction (AMI) in the Prehospital Setting (ASSENT 3 Plus)

Myocardial Infarction
Melbourne Health

Completed

Tenecteplase Versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (TASTEa)

Stroke, Acute, Stroke Ischemic

Australia
Beijing Tiantan Hospital

Recruiting

Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events-5 (TRACE-5)

Ischemic Stroke, Acute

China
University of Sydney
Genentech, Inc.

Recruiting

A Study of Low-dose Intracoronary Thrombolytic Therapy in STEMI (Heart Attack) Patients. (RESTORE-MI)

STEMI | Elevated IMR (>32)

Australia, New Zealand
University of Virginia
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B)

Stroke

United States
Beijing Tiantan Hospital

Recruiting

Intra-arterial Recombinant Human TNK Tissue-type Plasminogen Activator (rhTNK-tPA) Thrombolysis for Acute Large Vascular Occlusion After Successful Mechanical Thrombectomy Recanalization (ANGEL-TNK)

Ischemic Stroke, Acute

China
Medical Center of Central Georgia
Genentech, Inc.

Withdrawn

Treatment of Acute Respiratory Distress Syndrome With Tenecteplase: A Dose Escalation Pilot Study

Acute Respiratory Distress Syndrome

United States
General Hospital of Shenyang Military Region
Cerebrovascular Disease Collaboration & Innovation Alliance of Liaoning

Recruiting

Rescue Thrombolysis for Medium Vessel Occlusion (RESCUE-TNK)

Stroke, Ischemic

China
Kuwait University
University of Turku; University of Michigan

Completed

Effect of Xylitol on Oral Microbiota in Children

Bacterial Infections

Kuwait
General Hospital of Shenyang Military Region

Recruiting

Tenecteplase for Acute Ischemic Stroke Within 4.5 to 6 Hours of Onset (EXIT-BT2)

Stroke, Ischemic

China
General Hospital of Shenyang Military Region
Cerebrovascular Disease Collaboration & Innovation Alliance of Liaoning

Recruiting

Intra-arterial Tenecteplase During First Thrombectomy Attempt for Acute Stroke (BRETIS-TNK II)

Stroke, Ischemic

China
Hospital Universitari Vall d'Hebron Research Institute
Instituto de Salud Carlos III

Recruiting

Tenecteplase Compared to Alteplase for Patients With Large Vesel Oclusion Suspicion Before Thrombectomy

Acute Ischemic Stroke

Spain
University Hospital Inselspital, Berne

Recruiting

Safety and Efficacy of Intra-arterial Tenecteplase for Noncomplete Reperfusion of Intracranial Occlusions (TECNO)

Ischemic Stroke

Switzerland
General Hospital of Shenyang Military Region
Cerebrovascular Disease Collaboration & Innovation Alliance of Liaoning

Recruiting

Improving Neurological Outcome for Acute Basilar Artery Occlusion With Sufficient Recanalization After Thrombectomy by Intraarterial Tenecteplase (INSIST-IT)

Stroke, Ischemic

China
Genentech, Inc.

Completed

Tenecteplase in Stroke Patients Between 4.5 and 24 Hours (TIMELESS)

THROMBOLYSIS

United States, Canada
Neuroscience Trials Australia
The Florey Institute of Neuroscience and Mental Health

Completed

Determining the Optimal Dose of Tenecteplase Before Endovascular Therapy for Ischaemic Stroke (EXTEND-IA TNK Part 2)

Ischemic Stroke

Australia, New Zealand
Boehringer Ingelheim

Completed

Post Marketing Surveillance to Monitor the Safety and Efficacy of Metalyse® in Korean Patients With Acute Myocardial Infarction

Myocardial Infarction
Hospital Moinhos de Vento
Boehringer Ingelheim; Ministry of Health, Brazil; Medtronic

Recruiting

Randomization to Endovascular Treatment Alone or Preceded by Systemic Thrombolysis With Tenecteplase in Ischemic Stroke (DIRECT-TNK)

Stroke, Ischemic | Stroke, Acute

Brazil
Boehringer Ingelheim

Completed

Observational Study of METALYSE® in Patients With Acute Myocardial Infarction In Russian Federation

Myocardial Infarction
Oslo University Hospital

Recruiting

TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS) (TenCRAOS)

Central Retinal Artery Occlusion

Denmark, Norway, Belgium, Sweden, Finland, Ireland, Lithuania, Australia, Austria
AO GENERIUM

Recruiting

Study of Efficacy and Safety of GNR-060 vs Metalyse in Patients With ST Elevation Myocardial Infarction

ST Elevation Myocardial Infarction

Russian Federation
The First Affiliated Hospital of University of...

Completed

Intra-arterial TNK Following Endovascular Thrombectomy in Patients With Large Vessel Occlusion of Posterior Circulation

Acute Ischemic Stroke | Intracranial Artery Occlusion | Endovascular Thrombectomy

China

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