Search clinical trials for: JNJ-53718678, 4500 mg or Dose to be decided

Total 63 results

Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of JNJ-53718678 on the Cardiac Repolarization Interval in Healthy Adult Participants

Healthy

Belgium
Janssen Research & Development, LLC

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of JNJ-64179375 in Healthy Japanese Participants

Healthy

Japan, United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Explore the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of JNJ-53718678 at Two Dose Levels in Non-Hospitalized Adult Participants Infected With Respiratory Syncytial Virus

Respiratory Syncytial Virus Infections

United States, Taiwan, Japan, Korea, Republic of, France, Mexico, Brazil, Sweden, Argentina, Ukraine, Canada, Spain, Germany, Poland, Belgium, Russian Federation, South Africa, Australia, Bulgaria
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Oral Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-281959 / ACT-246475 in Healthy Male Subjects

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

France
Janssen Research & Development, LLC

Terminated

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-64140284 in Healthy Participants

Healthy

Belgium
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-389949 in Healthy Subjects

Healthy Subjects

United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Intravenous JNJ-64179375 Versus Oral Apixaban in Participants Undergoing Elective Total Knee Replacement Surgery (TEXT-TKR)

VTE Prophylaxis With Anticoagulation After Total Knee Replacement Surgery

Belgium, Italy, Malaysia, Latvia, Spain, Turkey, Bulgaria, United States, Lithuania, Russian Federation, Ukraine, Japan, Argentina, Brazil, Canada, Poland
Idorsia Pharmaceuticals Ltd.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-451840 in Healthy Subjects (Part A)

Healthy

France
GlaxoSmithKline

Completed

Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Repeat IV Doses

Infections, Respiratory Tract

Australia
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

MMV390048 and Its Antimalarial Activity Against Plasmodium Falciparum in Healthy Adult Subjects, Part B

Malaria

Australia
Gilead Sciences

Completed

Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-9669 in Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C

United States, Puerto Rico
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects

Viral Infection

United States
Corcept Therapeutics

Completed

A Study to Evaluate the Pharmacokinetics of the Current Capsule Formulation of CORT125134 in Healthy Subjects

Healthy

United States
Northwestern University
University of Iowa; University of Rochester; Michael J. Fox Foundation for Parkinson...

Completed

Nilotinib in Parkinson's Disease (NILO-PD)

Parkinson Disease

United States
University of Pittsburgh
Genentech, Inc.

Completed

Safety and Efficacy Study Using Bevacizumab, Capecitabine and Oxaliplatin for Colorectal Cancer

Cancer

United States
Hadassah Medical Organization

Terminated

TSO in Pediatric Autistic Spectrum Disorders (TSO)

Autistic Spectrum Disorders

Israel
Memorial Sloan Kettering Cancer Center
Pfizer; Dana-Farber Cancer Institute; University of Pittsburgh; University of Virginia

Completed

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

Neurofibromatosis | Meningioma | CNS Cancer | Hemangioblastoma | Intracranial Hemangiopericytoma

United States
Hospital for Special Surgery, New York

Completed

Effect of Steroids on Thrombosis (Blood Clot Formation) and Inflammation in Patients Undergoing Hip Surgery

Total Hip Replacement

United States
Cingulate Therapeutics
Rho, Inc.

Completed

Phase 3 Efficacy and Safety Study in Adults With ADHD Using CTx-1301.

ADHD | Attention Deficit Hyperactivity Disorder | ADHD - Combined Type | Attention Deficit Hyperactivity Disorder Combined

United States
Yuhan Corporation

Completed

Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of YH4808 After Oral Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Pfizer

Completed

Study to Assess Pharmacokinetics, Safety and Tolerability of PF-04965842 in Chinese Healthy Participants

HEALTHY

China
Assiut University

Unknown

Effects of Helicobacter Pylori Eradication in Children With Chronic Immune Thrombocytopenic Purpura

Immune Thrombocytopenia

Egypt
Memorial Sloan Kettering Cancer Center

Completed

Controlled Trial Comparing Nomogram-based Versus Standard Allocation of Acute Normovolemic Hemodilution (ANH) During Hepatic Resection

Liver Cancer

United States
Steve N. Caritis, MD
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Relationship Between Plasma Concentration of Hydroxyprogesterone Caproate (17-OHPC) and Preterm Birth (PRO)

Preterm Birth

United States
Eisai Limited

Terminated

A Study to Evaluate the Safety and Tolerability and Explore the Efficacy of Zonisamide as add-on Therapy in Elderly Patients With Refractory Partial Seizures

Epilepsy

United Kingdom, Germany, Hungary, Switzerland, Italy, Netherlands, Poland
Memorial Sloan Kettering Cancer Center
Celgene Corporation

Completed

Lenalidomide in Patients With Chronic Lymphocytic Leukemia Older Than 65 Years of Age

Leukemia | Chronic Lymphocytic Leukemia

United States
Ology Bioservices

Completed

Safety and Immunogenicity Study of a Ross River Virus (RRV) Vaccine

Ross River Virus Disease (RRVD)

Netherlands, Austria, Belgium
Mayo Clinic

Terminated

Study of Proton SBRT and Immunotherapy for Recurrent/Progressive Locoregional or Metastatic Head and Neck Cancer

Head and Neck Cancer

United States
University of California, Davis

Completed

Mechanisms of Immune Reconstitution & Reduced Immune Activation Following Darunavir-based ART

Human Immunodeficiency Virus Infection

United States
Memorial Sloan Kettering Cancer Center
Otsuka America Pharmaceutical; Ludwig Institute for Cancer Research

Completed

Busulfan, Melphalan, Fludarabine and T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Followed by Post Transplantation Donor Lymphocyte Infusions

Multiple Myeloma

United States
University of Roma La Sapienza

Unknown

Low-dose Statins and Nutraceuticals in High-intensity Statin-intolerant Patients (ADHERENCE)

Coronary Artery Disease

Italy
Memorial Sloan Kettering Cancer Center

Completed

Rituximab, Methotrexate, Procarbazine and Vincristine Followed by High-dose Chemotherapy With Autologous Stem-cell Rescue in Newly-diagnosed Primary CNS Lymphoma (PCNSL)

Non-Hodgkin's Lymphoma | CNS Lymphoma | CNS Brain Cancer

United States
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

Croatia, Bulgaria, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Romania, Ukraine, United States, Argentina, Czechia, Israel, Taiwan, Germany, Italy
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

Croatia, Brazil, Bulgaria, Korea, Republic of, Russian Federation, Hungary, Poland, Romania, Ukraine, Argentina, Israel, Portugal, Greece, Taiwan, Japan, Slovakia, Serbia, United States, Mexico, Germany, Turkey, Czechia
Memorial Sloan Kettering Cancer Center
Tufts Medical Center; Lahey Clinic

Completed

Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L

Multiple Myeloma

United States
Memorial Sloan Kettering Cancer Center

Completed

Busulfan, Melphalan, and Fludarabine With Peri-transplant Palifermin, Followed by a T-Cell Depleted Hematopoietic Stem Cell Transplant From HLA Matched or Mismatched Related or Unrelated Donors in Patients With Advanced Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia | Advanced Myelodysplastic Syndromes

United States
Assistance Publique - Hôpitaux de Paris
Aventis Pharmaceuticals

Completed

Celiprolol in Patients With Ehlers-Danlos Syndrome, Vascular Type

EHLERS-DANLOS SYNDROME, TYPE IV, AUTOSOMAL DOMINANT | CHROMOSOME 2q31.2 DELETION SYNDROME
Novartis Pharmaceuticals

Completed

Proof of Concept Study Evaluating the Efficacy and Safety of MIJ821 in Patients With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

Spain, United States
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Completed

Induction Therapy With Cytarabine, High-Dose Mitoxantrone and Dasatinib for Patients With Philadelphia-Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

Leukemia | Acute Lymphoblastic Leukemia

United States
University of Texas Southwestern Medical Center
National Center for Research Resources (NCRR)

Completed

Safety and Efficacy of Fluoxetine in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States
Lundquist Institute for Biomedical Innovation at...
Abbott Nutrition; DaVita Dialysis

Completed

Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients (AIONID)

Inflammation | Oxidative Stress | Hypoalbuminemia | Protein-energy Malnutrition | Chronic Kidney Disease (CKD) Hemodialysis

United States
Corcept Therapeutics

Completed

First-in-human Study in Healthy Subjects

Healthy

United Kingdom
Noven Therapeutics

Completed

Pharmacokinetic Evaluation of Brisdelle™ (Formerly Known as Mesafem) Following Single & Repeat Oral Administration in Healthy Postmenopausal Women (N30-005)

Postmenopausal Symptoms

United States
Noven Therapeutics

Completed

Eight-Week Efficacy & Safety Study of Brisdelle™ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms Associated With Menopause

Hot Flashes

United States
Novartis Pharmaceuticals

Completed

Study to Compare the Combination of Ribociclib Plus Goserelin Acetate With Hormonal Therapy Versus Combination Chemotherapy in Premenopausal or Perimenopausal Patients With Advanced or Metastatic Breast Cancer (RIGHT Choice)

Breast Cancer

India, Malaysia, Saudi Arabia, Taiwan, Russian Federation, Lebanon, South Africa, Thailand, Jordan, Turkey, Egypt, Vietnam, Singapore
Memorial Sloan Kettering Cancer Center

Completed

Fractionated Stem Cell Infusions in Myeloma Patients Undergoing Autologous Stem Cell Transplant

Multiple Myeloma

United States
Spanish Breast Cancer Research Group
Merck Sharp & Dohme LLC

Completed

Incidence of Chemotherapy-Induced Nausea and Vomiting Associated With Docetaxel-Cyclophosphamide in Early Breast Cancer.

Breast Cancer

Spain
Hellenic Institute for the Study of Sepsis

Completed

Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia (ACCESS)

Sepsis | Mortality | Inflammatory Response | Biomarkers | SIRS | Community-acquired Pneumonia

Greece
Hospital de Clinicas de Porto Alegre
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil; Conselho...

Unknown

Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy

Diabetes Mellitus | Arterial Hypertension

Brazil
Diagram B.V.

Completed

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent (REDUCE)

Acute Coronary Syndrome

Search clinical trials for: JNJ-53718678, 4500 mg or Dose to be decided

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