Search clinical trials for: L-ascorbic acid

Total 25570 results

University of Catanzaro

Unknown

Efficacy and Safety of Three Different Latanoprost 0,005% Eyedrops in Subjects Affected by Primary Open Angle Glaucoma (LATANOPROST)

Intraocular Pressure (IOP) | Tear Break-Up Time

Italy
Emalex Biosciences Inc.
Syneos Health; Cambridge Cognition Ltd

Recruiting

Drug Interaction Study

Drug Interaction

Canada
St. Jude Children's Research Hospital

Recruiting

Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

Rhabdomyosarcoma

United States
Assistance Publique - Hôpitaux de Paris
Roche Pharma AG

Recruiting

Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF (OBILUP)

Lupus Nephritis | Systemic Lupus Erythematosus (SLE)

France
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

HIV Infections | Tuberculosis

United States, Malawi, Puerto Rico, South Africa, Thailand, Zimbabwe, Brazil, Kenya, Uganda, India, Tanzania, Botswana
Fudan University

Recruiting

Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Versus no HIPEC in Locally Advanced Colorectal Cancer (APEC Study)

Locally Advanced Colorectal Cancer

China
Medical University of Vienna

Recruiting

Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma and ATRT (MEMMAT)

Medulloblastoma Recurrent | Ependymoma Recurrent | ATRT Recurrent

Austria, Sweden, France, Spain, United States, Czechia, Denmark, Norway
Hoffmann-La Roche
BioLineRx, Ltd.; Halozyme Therapeutics

Active, not recruiting

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma

United States, United Kingdom, Australia, Korea, Republic of, Taiwan, Israel, Spain
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of a Switch to Doravirine, Tenofovir, Lamivudine (MK-1439A) in Human Immunodeficiency Virus (HIV-1)-Infected Participants Virologically Suppressed on an Anti-retroviral Regimen in Combination With Two Nucleoside Reverse Transcriptase Inhibitors (MK-1439A-024) (DRIVE-SHIFT)

HIV-1 Infection
M.D. Anderson Cancer Center

Withdrawn

Pharmacologic Pretransplant Immunosuppression (PTIS) + Reduced Toxicity Conditioning (RTC) Allogeneic Stem Cell Transplantation in Inherited Hematologic Disorders

Stem Cell Transplantation

United States
BeiGene

Completed

Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer

Solid Tumor

Georgia, Moldova, Republic of, Poland, Slovakia
Medical Research Council

Active, not recruiting

Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy (STAMPEDE)

Prostate Cancer

United Kingdom, Switzerland
Queen Mary University of London
Cancer Research UK; Barts and the London School of Medicine and Dentistry

Completed

A Study to Examine the Effectiveness of Aspirin and/or Vitamin D3 to Prevent Prostate Cancer Progression (PROVENT)

Prostate Cancer

United Kingdom
Joseph Tuscano
Spectrum Pharmaceuticals, Inc

Active, not recruiting

Zevalin Before Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma

Relapsed Non Hodgkin Lymphoma | Refractory Non Hodgkin Lymphoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Efficacy and Safety of Dolutegravir-Containing Versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and Their Infants (VESTED)

HIV Infections

United States, South Africa, Thailand, Botswana, Brazil, Tanzania, Zimbabwe, India, Uganda
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Approved for marketing

Thymus Transplantation Safety-Efficacy

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Drug Interaction of PA-824, an Investigational Tuberculosis Medication, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampin

Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effects of Anti-HIV Therapy on Treatment for Hepatitis C in HCV/HIV Infected Adults

HIV Infections | Hepatitis C

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolites

HIV Infections | Bacterial Infections | Mycoses

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Study of Options for Second-Line Effective Combination Therapy (SELECT) (SELECT)

HIV-1 Infection

Peru, Kenya, Malawi, Brazil, South Africa, Zimbabwe, India, Thailand, Tanzania
BeiGene

Completed

Phase 1 Study to Investigate Effect of Rifampin and Itraconazole on the Pharmacokinetics of BGB-3111 in Healthy Subjects

Healthy Volunteers: Asian, Non-Asian

United States
Wen-Kai Weng

Completed

Non-myeloablative Allogeneic Transplantation for the Treatment of Multiple Myeloma

Multiple Myeloma | Blood Cancer

United States
Montefiore Medical Center
Nationwide Children's Hospital; Children's Hospital Los Angeles

Terminated

A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors

Solid Tumor | Allogeneic Hematopoietic Stem Cell Transplantation | Neuroepithelial Tumor

United States
St. Jude Children's Research Hospital
Assisi Foundation

Terminated

T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Myelocytic Leukemia | Myelodysplastic Syndrome | Acute Myelocytic Leukemia | Sarcoma, Myeloid | Hodgkin or Non-Hodgkin Lymphoma

United States
Hoffmann-La Roche

Completed

A Drug-Drug Interaction Study of Ketoconazole, Rifampicin and Ritonavir-Boosted Atazanavir With Single-Dose RO5093151 in Healthy Volunteers

Healthy Volunteer

United States
Eisai Inc.

Completed

A 3-Part, Open-Label, Drug-Drug Interaction Study of Concomitant Administration of E2609 With Itraconazole, Rifampin, Digoxin, or Donepezil

Healthy Subjects

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma and other conditions

United States
Samsung Medical Center

Completed

Kidney Graft Function Under the Immunosuppression Strategies (MyLowCsA)

Chronic Renal Disease
University of California, San Francisco
Merck Sharp & Dohme LLC; Gilead Sciences; National Institutes of Health (NIH); ...

Completed

Anti-Retrovirals for Kaposi's Sarcoma (ARKS)

HIV Infections | Kaposi's Sarcoma

Uganda
Universidad de Guanajuato
Antisepsia Central

Completed

Residual Effect of Chlorhexidine-alcohol Compared to Triclosan-alcohol

Infectious Diseases

Mexico
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

Combination Chemotherapy Followed by Donor Bone Marrow Transplant or Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer or Genetic Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm

United States
University of Carabobo
Clinical Research Unit at the Instituto Docente de Urologia; Northern Metropolitan... and other collaborators

Unknown

Novel Treatment for Coronary Artery Disease

Coronary Artery Disease

Venezuela
Harvard School of Public Health (HSPH)
Bristol-Myers Squibb; McGill University Health Centre/Research Institute of... and other collaborators

Completed

The Adult Antiretroviral Treatment and Resistance Study (Tshepo)

HIV Infection | AIDS

Botswana
Ohio State University

Recruiting

Achieving Nutritional Adequacy Of Vitamins E and K With An Egg/Plant-Based Food Pairing - Study 1

Nutritional Requirements

United States
Boehringer Ingelheim

Completed

A Study in Healthy People to Test Whether BI 730357 Affects How 4 Other Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Taken up in the Body

Healthy

Germany
Columbia University
Alpha-1 Foundation; Stony Wold-Herbert Fund, Inc.

Completed

Targeting Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency

Chronic Obstructive Pulmonary Disease | Emphysema | Alpha-1 Antitrypsin Deficiency

United States
Hams Hamed Abdelrahman

Completed

Glutamine With Topical Corticosteroids for Lichen Planus Treatment

Lichen Penis Planus

Egypt
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Intravenous JNJ-64179375 Versus Oral Apixaban in Participants Undergoing Elective Total Knee Replacement Surgery (TEXT-TKR)

VTE Prophylaxis With Anticoagulation After Total Knee Replacement Surgery

Belgium, Italy, Malaysia, Latvia, Spain, Turkey, Bulgaria, United States, Lithuania, Russian Federation, Ukraine, Japan, Argentina, Brazil, Canada, Poland
Assiut University

Unknown

Vitamin D Status in Inflammatory Bowel Disease (vdsinibd)

Inflammatory Bowel Diseases | Vitamin D Deficiency

Egypt
Ain Shams University

Completed

NAC in CC Resistant PCOS After LOD (NAC)

Clomiphene Citrate Resistant Polycystic Ovary Syndrome

Egypt
Centre Hospitalier Universitaire, Amiens

Terminated

Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients (NICOREN)

Hemodialysis | Chronic Renal Failure

France
Hoffmann-La Roche
Genentech, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants (POSTERITY)

Lupus Nephritis

United States, Brazil, Canada, France, Italy, Peru, South Africa, Spain, United Kingdom, Mexico, Poland, Russian Federation
University of Sydney
Northern Care Alliance NHS Foundation Trust; Waitemata District Health Board; Australasian Kidney Trials Network

Recruiting

Better Evidence and Translation for Calciphylaxis (BEAT-Calci)

Calciphylaxis

Australia, New Zealand
Cidara Therapeutics Inc.

Recruiting

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation (ReSPECT)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis | Invasive Fungal Disease | Pneumocystis | Mold Infection | Prophylaxis of Invasive Fungal Infections | Aspergillus

United States, Germany, France, Belgium, Canada, Italy, Spain, United Kingdom, Turkey, Switzerland
National Cancer Institute (NCI)

Completed

TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas

NSCLC | Solid Tumors | Lymphomas | Granulosa Cell Ovarian Cancer | Metastatic Colon Carcinoma

United States
University of Chicago
National Cancer Institute (NCI)

Active, not recruiting

Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer (OPTIMA)

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the Oropharynx

United States
Weill Medical College of Cornell University

Active, not recruiting

Targeting the IPA and Matching for the Non-Inherited Maternal Antigen for Haplo-Cord Transplantation

Hematologic Malignancies

United States
University of Nebraska
National Cancer Institute (NCI)

Withdrawn

Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Nonmalignant Neoplasm

United States
Kadmon Corporation, LLC
Quotient Sciences

Completed

Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers

Autoimmune Diseases | Drug-drug Interaction | Fibrotic Disease

United Kingdom
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Intra-Osseous Co-Transplant of UCB and hMSC

Myelodysplastic Syndromes | Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Refractory Chronic Lymphocytic Leukemia | Refractory Non-Hodgkin Lymphoma | Lymphoid Malignancies | Relapsed Non-Hodgkin Lymphoma and other conditions

United States

Search clinical trials for: L-ascorbic acid

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