Search clinical trials for: LPCN 1144

Total 232 results

Lipocine Inc.

Active, not recruiting

A Study of the Safety and Tolerability of LPCN 1144 in Subjects Who Completed the LPCN 1144-18-002 Trial

NASH - Nonalcoholic Steatohepatitis

United States
Lipocine Inc.

Completed

A Study to Assess the Efficacy, Safety, and Tolerability of Oral LPCN 1148 in Male Subjects With Cirrhosis of the Liver and Sarcopenia

Liver Cirrhosis | Sarcopenia

United States
Lipocine Inc.

Completed

The Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States
Avidity Biosciences, Inc.

Enrolling by invitation

Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy Participants With Mutations Amenable to Exon44 Skipping (EXPLORE44OLE)

Duchenne Muscular Dystrophy | DMD | Exon 44 | Duchenne

United States
ISDIN
Digna Biotech S.L.

Completed

Efficacy and Safety Study of p144 to Treat Skin Fibrosis in Systemic Sclerosis

Skin Fibrosis

Spain, United Kingdom, Germany, Poland, Hungary, Italy
Ain Shams University

Not yet recruiting

A Comparative Study Between Ultrasound Guided Erector Spinae Plane Block and Combined Ultrasound Guided Pericapsular Nerve Group and Lateral Femoral Nerve Block Following Total Hip Arthroplasty

Post Operative Pain
ISDIN
Digna Biotech S.L.

Completed

Open Label Extension (OLE) for the Patients Treated in the ISD002-P144-07 Study

Skin Fibrosis

United Kingdom, Spain, Italy, Poland, Germany, Hungary
Assiut University

Not yet recruiting

Pericapsular Nerve Group Block vs Supra Inguinal Fascia Iliaca Compartment Block

Pain, Postoperative
GEn1E Lifesciences

Recruiting

A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS)

Respiratory Distress Syndrome, Acute

United States
GEn1E Lifesciences

Completed

Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of GEn1E-1124

Healthy

New Zealand
ISDIN
Digna Biotech S.L.

Completed

Tolerability and Bioavailability of the P144 Peptide Inhibitor of TGF-β1 After Topical Administration in Healthy Volunteers

Healthy

Spain
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
Merck KGaA, Darmstadt, Germany

Completed

PK Study of Xevinapant (Debio 1143) in Healthy East Asian Participants

Healthy

United Kingdom
Alkermes, Inc.

Terminated

Phase 1 ALKS 1140 in Healthy Adults

Central Nervous System Diseases

Australia
Avidity Biosciences, Inc.

Recruiting

Study of AOC 1044 in Healthy Adult Volunteers and Participants With Duchenne Muscular Dystrophy (DMD) Mutations Amenable to Exon 44 Skipping (EXPLORE44)

Duchenne Muscular Dystrophy | Exon 44

United States
Molecular Insight Pharmaceuticals, Inc.

Terminated

Phase I Safety and Dosimetry Study in Patients With Confirmed Metastatic Melanoma

Metastatic Melanoma

United States
Debiopharm International SA

Completed

Dose Escalation Study of Safety and Tolerability of AT-406 in Patients With Advanced Solid Tumors and Lymphomas

Lymphoma | Cancer | Solid Tumors | Malignancy

United States
Takeda

Completed

TAK-114 Single- and Multiple-Dose Phase 1 Study

Clinical Pharmacology

Japan
ORIC Pharmaceuticals

Completed

Effect of Food on the Pharmacokinetics of ORIC-114

Food Effect in Healthy Participants

Australia
Fusion Pharma LLC
Data Matrix Solutions; OCT Rus, LLC; Skolkovo Innovation Center

Unknown

Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene

Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Chronic Myeloid Leukemia

Russian Federation
Amgen

Terminated

A Study of AMG 114 Administered by Subcutaneous Injection for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies Receiving Multicycle Chemotherapy

Cancer | Anemia
Derince Training and Research Hospital
Bursa Yüksek İhtisas Education and Research Hospital

Completed

Comparison of the Efficacy of PENG Block in Combination With LFCN Block and Wound Infiltration

Postoperative Pain

Turkey
Placon Therapeutics

Unknown

A Study to Determine the Safety of BTP-114 for Treatment in Patients With Advanced Solid Tumors With BRCA Mutations

Breast Neoplasms | Prostatic Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms

United States
Memorial Sloan Kettering Cancer Center
Iovance Biotherapeutics, Inc.

Recruiting

Pilot Trial of Autologous Tumor Infiltrating Lymphocytes (LN-144) for Patients With Metastatic Uveal Melanoma

Melanoma | Metastatic Melanoma | Metastatic Uveal Melanoma | Uveal Melanoma

United States
Washington University School of Medicine
National Cancer Institute (NCI); The Foundation for Barnes-Jewish Hospital; Celldex...

Terminated

Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients

Pancreatic Cancer | Pancreas Cancer | Cancer of the Pancreas

United States
ModernaTX, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of mRNA-1944 in Healthy Adults

Prevention of Chikungunya Virus Infection

United States
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of Increasing Repeated Doses of BIIF 1149 BS in Healthy Male Volunteers

Healthy
Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population

Healthy Volunteer | Vasomotor System; Labile

China
Escalier Biosciences B.V.
Innovaderm Research Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Topical ESR-114 in Subjects With Plaque Psoriasis

Psoriatic Plaque

United States, Canada
Changchun GeneScience Pharmaceutical Co., Ltd.
Syneos Health

Recruiting

A Study to Assess Safety and Tolerability of GS1-144 in Healthy Volunteers

Vasomotor Symptoms | Adult Healthy Volunteers

Australia
Avobis Bio, LLC
Alimentiv Inc.

Recruiting

Seeded Cells on Matrix Plug Treating Crohn's Perianal Fistulas (STOMP-II)

Crohn's Disease | Perianal Fistula

United States
Taiho Pharmaceutical Co., Ltd.

Completed

A Study of TAS-114 in Combination With S-1 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

Japan
Zonguldak Bulent Ecevit University

Active, not recruiting

'The Effect of Adding LFCN Block to PENG

Pain, Postoperative | Pain, Acute | Nerve Block | Opioid Consumption

Turkey
Konya Necmettin Erbakan Üniversitesi

Completed

Comparison of Pericapsular Nerve Group Block and Quadratus Lumborum Block

Total Hip Surgery | Pericapsular Nerve | Quadratus Lumborum

Turkey
Lukas J Hefermehl
Kantonsspital Baden

Recruiting

Comparing Two Different Approaches in Robotic-Assisted Renal Surgery (PIONEER-OPT)

Renal Tumor

Switzerland
IlDong Pharmaceutical Co Ltd

Unknown

Study to Evaluate Pharmacokinetics, Safety, and Tolerability Ildong COL-144 Tablet in Korean Healthy Volunteers

Healthy
Boehringer Ingelheim

Completed

Efficacy and Safety of 4 Weeks Treatment With Inhaled BI 1744 CL in Japanese Patients With COPD

Pulmonary Disease, Chronic Obstructive

Japan
Tego Science, Inc.

Completed

A Phase I/III Clinical Study of TPX-114 for the Treatment of Full-Thickness Rotator Cuff Tear

Rotator Cuff Injuries

Korea, Republic of
Praxis Precision Medicines

Completed

A Clinical Trial of Adjunctive and Monotherapy PRAX-114 in Participants With Major Depressive Disorder

Major Depressive Disorder

United States, Australia
Shanghai Mental Health Center
Shanghai Jiao Tong University School of Medicine

Unknown

Modulation of Repetitive Transcranial Magnetic Stimulation on Hippocampal Neurogenesis and Functional Network in Patients With Schizophrenia

Schizophrenia

China
Orthofix Inc.

Terminated

PEMF as Adjunctive Treatment Following Surgical Repair of Full Thickness Rotator Cuff Tears (RCStim)

Full-thickness Rotator Cuff Tear

United States
Avilex Pharma

Completed

A Phase 1 Study in Healthy Volunteers to Evaluate the Safety, Tolerability and Pharmacokinetics of AVLX-144

Tolerance | Safety Issues

Finland
ConjuChem

Completed

A Study to Evaluate the Efficacy and Safety of CJC-1134-PC in Patients With Type 2 Diabetes Mellitus Who Are Currently on Metformin Monotherapy (DM200-101)

Type 2 Diabetes Mellitus

Canada
Palo Alto Veterans Institute for Research
National Institute on Aging (NIA)

Completed

Noninvasive Brain Stimulation for Mild Cognitive Impairment

Cognitive Dysfunction | Mild Cognitive Impairment | Cognitive Decline | Memory Impairment | Memory Loss | Mild Neurocognitive Disorder | Mental Deterioration | Memory Decline

United States
Daacro
DuPont Nutrition and Health

Completed

Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects

Healthy | Stress, Psychological

Germany
Praxis Precision Medicines

Withdrawn

A Clinical Trial of PRAX-114 in Participants With Essential Tremor

Essential Tremor

United States
Iovance Biotherapeutics, Inc.

No longer available

Expanded Access Program of Lifileucel (LN-144) in Patients With Unresectable or Metastatic Melanoma

Metastatic Melanoma | Unresectable Melanoma

United States
Iovance Biotherapeutics, Inc.

Active, not recruiting

Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma (LN-144)

Metastatic Melanoma

United States, Spain, Germany, United Kingdom, France, Hungary, Italy, Switzerland
Gilead Sciences

Terminated

Phase I Dose Escalation Study of IMMU-114 in Relapsed or Refractory NHL and CLL

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Non-hodgkin's Lymphoma | Small Lymphocytic Lymphoma

United States
Boehringer Ingelheim

Completed

A Study of the Safety and Efficacy of 4 Doses of BI 1744 CL Delivered Via the Respimat in Patients With Asthma.

Asthma

Austria, Germany, Poland, Romania, Slovakia, Slovenia
Mansoura University

Unknown

Which Analgesia is Better for Proximal Femoral Fractures?

Proximal Femur Fracture

Egypt

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