Search clinical trials for: MEK162
Total 68 results
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PfizerCompletedBRAF or NRAS Mutant Metastatic MelanomaUnited States, Netherlands, Italy, Germany, Switzerland
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Array Biopharma, now a wholly owned subsidiary...CompletedAdvanced Solid TumorJapan
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PfizerCompletedSolid Tumor and Hematologic MalignanciesUnited States
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Array Biopharma, now a wholly owned subsidiary...WithdrawnCardiomegalyUnited States, United Kingdom
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Array Biopharma, now a wholly owned subsidiary...CompletedAdvanced Solid TumorsUnited States, Spain, Canada, Norway, Switzerland
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Array BioPharmaCompletedAML | Advanced and Selected Solid Tumors | High Risk and Very High Risk MDSUnited States, Australia, Italy, Spain, France, Switzerland, United Kingdom
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PfizerCompletedLocally Advanced or Metastatic NRAS Mutant MelanomaUnited States, Australia, Germany, Italy, Netherlands
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Array Biopharma, now a wholly owned subsidiary...CompletedAdvanced Solid Tumors | Selected Solid TumorsUnited States, Germany, Canada, Spain, Netherlands, Singapore, Switzerland
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PfizerCompletedSolid Tumors Harboring a BRAF V600 MutationUnited States, France, Italy, Singapore, Australia, Spain, Switzerland, Canada, Belgium
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Memorial Sloan Kettering Cancer CenterPlexxikon; Array BioPharmaCompletedGastrointestinal Stromal Tumor (GIST)United States
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PfizerTerminatedMetastatic Pancreatic Adenocarcinoma | BRAF Mutated MelanomaUnited States, Australia, Belgium, Canada, France, Italy, Spain, United Kingdom
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Array Biopharma, now a wholly owned subsidiary...TerminatedUveal MelanomaUnited States, France, Germany, Netherlands, Spain, United Kingdom
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University of Heidelberg Medical CenterGerman Cancer Research Center; University Hospital Heidelberg; Array BioPharma; Coordinating Centre for Clinical Trials HeidelbergActive, not recruitingRelapsed or Refractory Multiple Myeloma | Patients With BRAFV600 E or BRAFV600K MutationGermany
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Array Biopharma, now a wholly owned subsidiary...TerminatedHepatic ImpairmentUnited States
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National Cancer Institute (NCI)Active, not recruitingHematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple MyelomaUnited States
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Memorial Sloan Kettering Cancer CenterArray BioPharmaCompletedAdvanced BRAF Mutant CancersUnited States
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Seoul National University HospitalCompletedBiliary Tract CancerKorea, Republic of
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University of UtahPfizerCompletedAdvanced KRAS Positive Metastatic Colorectal CancerUnited States
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PfizerCompletedSolid Tumor | Unspecified Adult Solid Tumor, Protocol SpecificUnited States, Australia, Canada, France, Spain
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PfizerCompletedMelanomaUnited States, Australia, Canada, Germany, Italy, Netherlands, Spain, Switzerland, United Kingdom
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)TerminatedMetastatic Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Recurrent Pancreatic Carcinoma | Locally Advanced Pancreatic CarcinomaUnited States
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University of California, San FranciscoTakeda; Array BioPharmaTerminatedProgressive Disease | Stage IV Lung Cancer | Lung Non-Small Cell Carcinoma | ROS1 Gene Rearrangement | ALK Gene Rearrangement | Stage IIIB Lung Cancer | Stage IIIC Lung Cancer | Stage IVA Lung Cancer | Stage IVB Lung CancerUnited States
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Array Biopharma, now a wholly owned subsidiary...CompletedMetastatic Colorectal Cancer | Advanced Solid Tumors | Advanced or Metastatic Biliary CancerUnited States
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PfizerCompletedMetastatic Colorectal CancerBelgium, Canada, France, Spain, United States, Italy, Netherlands
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M.D. Anderson Cancer CenterRecruitingMetastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8United States
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PfizerTerminatedLow-grade Serous Ovarian Cancer | Low-grade Serous Fallopian Tube Cancer | Low-grade Serous Peritoneal CancerUnited States, Canada, Hungary, Spain, Belgium, France, United Kingdom, Australia, Czechia, Netherlands, Sweden, Italy, Denmark, Germany, Austria, Finland, Ireland, Norway, Poland
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Children's Hospital Los AngelesDana-Farber Cancer InstituteActive, not recruitingSoft Tissue Neoplasms | Low-Grade Gliomas | Malignant Neoplasms, BrainUnited States
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Jonsson Comprehensive Cancer CenterNational Cancer Institute (NCI)WithdrawnRecurrent Melanoma | Stage IV MelanomaUnited States
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PfizerCompletedMetastatic or Unresectable Cutaneous MelanomaUnited States, Spain, Canada, Italy, United Kingdom, Germany, Korea, Republic of, France, Australia, Czechia, Russian Federation, Turkey, Israel, Netherlands, Greece, Hungary, Japan, Portugal, Argentina, Austria, Belgium, Brazil, Po... and more
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Novartis PharmaceuticalsCompletedAdenocarcinoma Lung Cancer; Squamous Cell Lung CarcinomaChina
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Dana-Farber Cancer InstitutePfizer; Array BioPharmaActive, not recruiting
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PfizerRecruitingGlioma | Melanoma | Thyroid Cancer | Non-Small-Cell Lung CancerUnited States, Canada, Israel
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University of California, San FranciscoArray BioPharmaRecruitingMelanoma Stage IV | Melanoma Stage IIIUnited States
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PfizerActive, not recruitingMelanomaCanada, United States, Spain, Germany, Korea, Republic of, Australia, Czechia, Netherlands, France, Hungary, United Kingdom, Switzerland, Singapore, Russian Federation, Italy, Japan, Israel, Brazil, Portugal, Mexico, Greece, Argen... and more
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Pierre Fabre MedicamentActive, not recruiting
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Swiss Group for Clinical Cancer ResearchCompletedLung Cancer | KRAS Gene Mutation | Advanced Non-small Cell Lung CancerSwitzerland
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University of OxfordPfizer; Belfast Health and Social Care Trust; Queen's University, Belfast; Saint... and other collaboratorsCompletedColorectal Cancer | Solid TumorUnited Kingdom
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Array Biopharma, now a wholly owned subsidiary...CompletedFallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal CancerUnited States
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Memorial Sloan Kettering Cancer CenterActive, not recruitingGastrointestinal Stromal Tumor (GIST)United States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingStage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic AdenocarcinomaUnited States
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Mayo ClinicNational Cancer Institute (NCI)CompletedMetastatic Triple-Negative Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7 | Breast AdenocarcinomaUnited States
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PfizerActive, not recruiting
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University Health Network, TorontoNovartis PharmaceuticalsCompleted
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Fondazione Melanoma OnlusClinical Research Technology S.r.l.Active, not recruitingMetastatic MelanomaItaly, Germany, Spain, Greece, Austria, France, Poland, Sweden, Switzerland, United Kingdom
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Jonsson Comprehensive Cancer CenterNovartis PharmaceuticalsWithdrawnRecurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung CancerUnited States
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PfizerTerminatedPancreatic CancerBelgium, United States, Singapore
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Memorial Sloan Kettering Cancer CenterArray BioPharmaCompletedAdvanced Biliary Tract CarcinomaUnited States
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Jonsson Comprehensive Cancer CenterBristol-Myers Squibb; Array BioPharmaRecruitingMetastatic Cutaneous Melanoma | Unresectable Cutaneous Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage III Cutaneous... and other conditionsUnited States
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Providence Health & ServicesRecruitingBRAF V600E Mutation Present | Stage IV Differentiated Thyroid Gland Carcinoma AJCC v8 | Refractory Thyroid Gland Carcinoma | Metastatic Thyroid Gland Carcinoma | BRAF NP_004324.2:p.V600M | Stage IVA Differentiated Thyroid Gland Carcinoma AJCC v8 | Stage IVB Differentiated Thyroid Gland Carcinoma...United States
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City of Hope Medical CenterNational Cancer Institute (NCI); Array BioPharmaCompletedRecurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal CancerUnited States