Search clinical trials for: MK0653A , ezetimibe ( ) simvastatin

Total 928 results

Organon and Co

Completed

MK0653C in High Cardiovascular Risk Patients With High Cholesterol (Switch Study)(MK-0653C-162)

Hypercholesterolemia
Yuhan Corporation

Completed

Comparison of High-dose Rosuvastatin Versus Low-dose Rosuvastatin Plus Ezetimibe on Carotid Plaque Inflammation in Patients With Acute Coronary Syndrome

Acute Coronary Syndrome | Carotid Atherosclerotic Plaque With Inflammation

Korea, Republic of
Government Dental College and Research Institute...

Completed

Comparative Evaluation Of 1.2% Atorvastatin and 1.2% Simvastatin Gel Local Drug Delivery And Redelivery In Chronic Periodontitis Subjects With Diabetes Mellitus: A Randomized Controlled Clinical Trial.

Chronic Periodontitis Wth Diabetes Mellitus

India
Beijing Anzhen Hospital
Beijing Municipal Health Commission

Not yet recruiting

Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis: A Randomized Trial (EPISODE)

Aortic Stenosis

China
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4 (GAUSS-4)

Hypercholesterolemia

Japan
Osaka University
Kowa Company, Ltd.

Terminated

The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's Disease (PIT-ROAD)

Alzheimer Disease | Hypercholesterolemia

Japan
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

High Potency Statins and the Risk of Diabetes (Statins-DM)

Cardiovascular Disease | Diabetes Mellitus, Type 2
Abbott

Completed

An Open-Label Study to Compare the Lipid Effects of Niacin ER and Simvastatin (NS) to Atorvastatin in Subjects With Hyperlipidemia or Mixed Dyslipidemia (SUPREME) (SUPREME)

Hyperlipidemia | Mixed Dyslipidemia

United States
National Cancer Center, Korea
Boehringer Ingelheim

Completed

BIBW 2992 Plus Simvastatin vs. BIBW 2992 in Previously Treated Patients With Advanced Non-adenocarcinomatous NSCLC

Non-small Cell Lung Cancer

Korea, Republic of
Seoul National University Hospital

Completed

Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers

Simvastatin Pharmacokinetics and Gut Microbiome

Korea, Republic of
Government Dental College and Research Institute...

Completed

Platelet Rich Fibrin Combined With Simvastatin for Treatment of Intrabony Defect in Chronic Periodontitis

Three Wall Intrabony Defects in Chronic Periodontitis

India
National Cancer Center, Korea

Active, not recruiting

Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer

Small Cell Lung Carcinoma

Korea, Republic of
University of California, San Diego
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Statin Medications on Mental Processes, Behavior, and Serotonin Levels

Dyslipidemias

United States
Seoul National University Bundang Hospital
Korea United Pharm. Inc.

Recruiting

Atmeg (Atorvastatin and Omega-3 Combination) and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia

Diabetes Mellitus, Type 2 | Atherosclerosis | Dyslipidemias

Korea, Republic of
Kaiser Permanente
Esperion Therapeutics, Inc.

Not yet recruiting

Cholesterol Lowering Via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome Study

Cardiovascular Diseases | STEMI | NSTEMI

United States
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2 (GAUSS-2)

Hyperlipidemia

United States, Denmark, Belgium, Germany, Hong Kong, Netherlands, France, Australia, Canada, South Africa, United Kingdom, Spain, Poland, Switzerland
Sanofi

Completed

A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapy (ROZEL)

Hypercholesterolemia

China
Yuhan Corporation
Linical Korea

Completed

A Study to Compare Rosuvastatin/Ezetimibe and Rosuvastatin in Patients With Diabetes Mellitus and Hypercholesterolemia

Diabetes Mellitus and Hypercholesterolemia

Korea, Republic of
Thammasat University

Completed

Efficacy of High and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcome in Patients With AIS

Ischemic Stroke
Institute of Liver and Biliary Sciences, India

Recruiting

To Study the Safety and Efficacy of Simvastatin in Patients With Hepatopulmonary Syndrome in Cirrhosis.

Liver Cirrhosis

India
Poznan University of Medical Sciences
Yale University

Unknown

Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial.

Polycystic Ovary Syndrome

Poland
Texas A&M University
Nutrabolt

Completed

Safety of Different Forms of Creatine (NB9)

Nutritional Supplements
Chinese University of Hong Kong

Completed

Genome-wide Analysis of Lipid-lowering Efficacy and Drug Level of Simvastatin and Rosuvastatin

Hypercholesterolemia

Hong Kong
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Hypercholesterolemia | LDL Cholesterol

United States
Lund University

Recruiting

Treatment of Graves´Ophthalmopathy With Simvastatin (GO-S)

Graves Ophthalmopathy | Thyroid Associated Ophthalmopathy | Thyroid Associated Orbitopathy

Sweden
Mitsubishi Tanabe Pharma Corporation

Completed

A Study to Investigate the Effect of MT-8554 on the Pharmacokinetics of Simvastatin and Rosuvastatin in Healthy Subjects

Healthy

United Kingdom
Mahidol University

Completed

The Effects of Simvastatin on Th17 Cytokines and Th17 Polarizing Cytokine in COPD Patients

COPD

Thailand
National Cancer Center, Korea

Completed

Gefitinib With or Without Simvastatin in Non-Small Cell Lung Cancer (NSCLC)

Lung Cancer

Korea, Republic of
Mayo Clinic

Completed

Statin Interchange by Pharmacist Collaborative Practice Agreement (CPA)

Hypercholesterolemia

United States
Provident Clinical Research
Reliant Pharmaceuticals

Unknown

An Open-Label Extension to Assess the Continued Efficacy of Omacor Plus Simvastatin

Mixed Dyslipidemia
Charite University, Berlin, Germany
NeuroCure Clinical Research Center, Charite, Berlin; University Medical Center...

Recruiting

Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major Depression (SIMCODE)

Obesity | Depressive Disorder, Major

Germany
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Recruiting

Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia (MILOS)

Hypercholesterolemia | Mixed Dyslipidemia

Austria, United Kingdom, Italy, Germany, Belgium
Laboratorios Silanes S.A. de C.V.

Completed

Study to Evaluate the Safety of the Fixed-dose Combination Rosuvastatin/Ezetimibe for Patients With Dyslipidaemia (TREZETE)

Dyslipidemias

Mexico
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe on Top of Statin in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY COMBO II)

Hypercholesterolemia

United States, Canada, Denmark, France, Hungary, Israel, Korea, Republic of, Russian Federation, South Africa, Ukraine
Kiyuk Chang, MD,PhD

Recruiting

Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI (ROSUZET-AMI)

Myocardial Infarction | Statin Adverse Reaction | HMG-CoA Reductase Inhibitor Toxicity

Korea, Republic of
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Withdrawn

Treatment With Bempedoic Acid And/Or Its Fixed-dose Combination With Ezetimibe in Routine Clinical Practice in Patients With Primary Hypercholesterolemia Or Mixed Dyslipidemia (MILOS-Spain)

Mixed Dyslipidemia | Primary Hypercholesterolemia
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Administering Multiple Oral Doses of GSK1292263 Alone and With Atorvastatin

Dyslipidemias | Dyslipidaemias

United States
University of Oxford
Merck Sharp & Dohme LLC

Completed

Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH)

Cardiovascular Disease

United Kingdom
University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
Organon and Co

Completed

Effect of Ezetimibe Treatment on Low-density Lipoprotein Cholesterol (LDL-C) Levels in Participants With Coronary Heart Disease (CHD) Already Treated With a Statin (MK-0653A-205 AM1) (ACT II)

Hypercholesterolemia
International Bio service

Not yet recruiting

Bioequivalence Study of Simvastatin 40 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
University of California, San Diego
American Heart Association

Completed

Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity

Statin Intolerance

United States
GlaxoSmithKline

Completed

Open-Label Extension of a Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lovaza® and Simvastatin Therapy in Hypertriglyceridemic Subjects

Hypertriglyceridemia

United States
University of Louisville
James Graham Brown Cancer Center

Terminated

Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid

Multiple Myeloma

United States
Government Dental College and Research Institute...

Completed

1.2% Atorvastatin and 1.2% Simvastatin in Treatment of Chronic Periodontitis

Chronic Periodontitis
Leiden University Medical Center

Unknown

Cetuximab and Simvastatin in Treating Patients With Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

Netherlands
Shanghai Pulmonary Hospital, Shanghai, China
Chinese Academy of Sciences

Not yet recruiting

Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy

Small Cell Lung Cancer

China
University of Kansas Medical Center
University of Missouri-Columbia; American Heart Association

Completed

Exercise, Statins, and the Metabolic Syndrome

Metabolic Syndrome | Obese | Sedentary

United States
Ziauddin Hospital

Unknown

Ezetimibe for Patients With Chronic Hepatitis D

Chronic Hepatitis D

Pakistan
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Effectiveness, and Tolerability of Ezetimibe Combined With Statins for the Treatment of High Cholesterol in HIV Infected Adults

HIV Infections

United States, Puerto Rico

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