Search clinical trials for: MSK-2206

Total 4202 results

Chinese University of Hong Kong

Completed

MK-2206 in Recurrent Nasopharyngeal Carcinoma (MC1079)

Recurrent Nasopharyngeal Carcinoma

Hong Kong
Dana-Farber Cancer Institute
Memorial Sloan Kettering Cancer Center; Massachusetts General Hospital; University... and other collaborators

Withdrawn

MK-2206 for Recurrent Malignant Glioma

Malignant Glioma

United States
Merck Sharp & Dohme LLC

Completed

Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-2206-002)

Neoplasms | Cancer | Metastatic Solid Tumors | Locally Advanced Tumors
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC

Completed

Study of MK-2206 in Patients With Metastatic Neuroendocrine Tumors (NET)

PANCREAS | Neuroendocrine

United States
Merck Sharp & Dohme LLC

Terminated

A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)

Neoplasms Malignant
National Cancer Institute (NCI)

Active, not recruiting

Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer

Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Advanced Malignant Solid Neoplasm | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage III Renal Cell Cancer AJCC v7 | Stage IV Renal Cell Cancer AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma... and other conditions

United States
Merck Sharp & Dohme LLC
AstraZeneca

Completed

A Combination Therapy Study of MK-2206 and AZD6244 in Participants With Advanced Solid Tumors (MK-2206-010)

Locally Advanced or Metastatic Solid Tumors
National Cancer Institute (NCI)

Completed

MK-2206 and AZD6244 in Patients With Advanced Colorectal Carcinoma

Colorectal Neoplasms

United States
National Cancer Institute (NCI)

Active, not recruiting

Bicalutamide With or Without Akt Inhibitor MK2206 in Treating Patients With Previously Treated Prostate Cancer

Recurrent Prostate Carcinoma | Stage IIA Prostate Cancer AJCC v7 | Stage III Prostate Cancer AJCC v7 | Stage I Prostate Cancer AJCC v7 | Stage IIB Prostate Cancer AJCC v7

United States, Ireland
Merck Sharp & Dohme LLC

Completed

Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049)

Advanced Cancer
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC

Terminated

Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal Cancer

Rectal Cancer | Colon Cancer

United States
UConn Health
Medical College of Wisconsin

Completed

Study of Freeze-dried Black Raspberry in Maintenance of Ulcerative Colitis (BRB)

Ulcerative Colitis

United States
King's College London
Washington Red Raspberries Commission

Recruiting

Gut Microbial Metabolism of Polyphenols and Cardiovascular Health (StratiPol) (Stratification Study) (StratiPol)

Healthy

United Kingdom
Jeil Pharmaceutical Co., Ltd.

Recruiting

Safety, Tolerability, and Pharmacokinetic and Pharmacodynamic Characteristics of JP-2266 in Healthy Subjects

Diabetes Mellitus

France
Novartis Pharmaceuticals

Active, not recruiting

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors (LuMIERE) (LuMIERE)

Solid Tumor

United States
NVP Healthcare

Completed

To Evaluate the Safety and the Pharmacokinetics of NVP-2203

Healthy Volunteers

Korea, Republic of
GlaxoSmithKline

Completed

Non-Inferiority of Various GSK Bio's Influenza Vaccine Presentations in Adults Aged 65 Years and Over

Influenza

Norway, Estonia, Denmark
Dong-A ST Co., Ltd.

Completed

Pharmacokinetics and Safety/Tolerability Profiles of DA-5206 Versus Talion® Under Fasting and Fed States in Healthy Male Subjects

Healthy

Korea, Republic of
NVP Healthcare

Recruiting

To Evaluate the Safety and Efficacy of NVP-2203 Tablet in Patients

Cardiovascular Diseases

Korea, Republic of
Celgene

Completed

2-part Study to Assess Safety, Pharmacokinetics & Pharmacodynamics of CC-220 & Effect of Food on CC-220 in Healthy Subjects

Healthy

United States
Merck Sharp & Dohme LLC

Terminated

A Study of MK-2206 in Combination With Trastuzumab and Lapatinib for the Treatment of HER2+ Solid Tumors (MK-2206-015)

Breast Cancer | Advanced Solid Tumors
Vanderbilt-Ingram Cancer Center

Withdrawn

MK-2206+Endocrine Therapy in Patients With Hormone Receptor-Positive Breast Cancer

Metastatic Breast Cancer
Samik Pharmaceutical Co. Ltd.

Completed

A Clinical Trial to Evaluate the Pharmacokinetics and Safety of SIPS-2209-1 in Healthy Korean Volunteers

Healthy

Korea, Republic of
Ono Pharma USA Inc

Terminated

A Study to Evaluate the Effects of ONO-2506 Intravenous Infusion in Patients With Acute Ischemic Stroke

Cerebrovascular Accident

United States, Canada
Kyowa Kirin Co., Ltd.

Completed

A Comparative Study of KW-2246 (2246-004)

Cancer Related Pain (Breakthrough Pain)

Japan
Nguyen Thi Trieu, MD

Completed

Prevention and Treatment of Patient Before, During, and After Covid-19 Infection (AntiCov-220)

Covid19

Vietnam
University of California, San Francisco
Merck Sharp & Dohme LLC

Completed

MK-2206, Paclitaxel and Trastuzumab in Treating Patients With HER2-overexpressing Solid Tumor Malignancies

Cancer | Advanced Solid Tumors | Tumors

United States
Thomas Hope
Clovis Oncology, Inc.

Recruiting

Imaging of Solid Tumors Using FAP-2286

Metastatic Cancer | Solid Tumors, Adult

United States
University of Turin, Italy

Completed

Diuretic Response in Advanced Heart Failure: Bolus Intermittent vs Continuous INfusion (DRAIN)

Heart Failure NYHA Class III | Heart Failure NYHA Class IV

Italy
Guangdong Hengrui Pharmaceutical Co., Ltd

Enrolling by invitation

Safety and Tolerance of Increased Doses of SHR-2106 Injection in Healthy Subjects

Kidney Transplantation

China
CytRx

Withdrawn

INNO-206 in Patients With Small Cell Lung Cancer (SCLC)

Small Cell Lung Cancer

United States
University of Florida

Withdrawn

Standardized Home Exercise Prescription Education

Knowledge, Attitudes, Practice | Behavior
Keele University
University of Oxford; Arthritis Research UK; Pro-Mapp Limited Company number... and other collaborators

Completed

The MSK-Tracker Study (MSK-Tracker)

Musculoskeletal Pain

United Kingdom
Inter-American Development Bank
Universidade Federal do Ceará; Municipal Secretary of Health, Fortaleza Brasil

Unknown

Evaluation of the Home Visiting Pilot Program on Early Childhood Outcomes in Fortaleza Brazil

Child Development
Celgene

Completed

A Study to Assess the Relative Bioavailability of a New CC-220 Capsule Formulation, Compared to a Reference CC-220 Capsule Formulation, in Healthy Adult Subjects

Healthy Volunteers

United States
Ono Pharmaceutical Co. Ltd

Completed

Study of ONO-2506 in Patients With Acute Ischemic Stroke

Stroke

Japan
Targacept Inc.

Completed

A Safety and Tolerability Single Ascending Dose Study in Healthy Volunteers (SRD)

Healthy

France
Pamukkale University

Completed

Effects of Face Masks on Cardiopulmonary Capacity in Healthy Individuals

Covid-19

Turkey
Celgene

Completed

A Study to Evaluate the Efficacy and Safety of CC-220 in Subjects With Active Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic

United States, Belgium, Germany, Spain, Canada, Serbia, Colombia, Poland, Argentina, Brazil, Mexico, Hungary, France, Russian Federation, Italy
BlueRock Therapeutics
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Phase 1 Safety and Tolerability Study of MSK-DA01 Cell Therapy for Advanced Parkinson's Disease

Advanced Parkinson's Disease

United States, Canada
Thomas Hope
Clovis Oncology, Inc.

Recruiting

Imaging of Pathologic Fibrosis Using 68Ga-FAP-2286

Myocardial Fibrosis | Pulmonary Fibrosis | Liver Fibrosis

United States
Red de Terapia Celular
University of Valladolid; Hospital del Río Hortega; Hospital Clínico Universitario... and other collaborators

Recruiting

Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells (MSV_LE)

Lupus Nephritis | Lupus Erythematosus

Spain
Cancer Research UK
BioInvent International AB; Bloodwise

Completed

BI-1206 and an Anti-CD20 Antibody in Patients With CD32b Positive B-cell Lymphoma or Leukaemia

B-cell Lymphoma | Waldenström Macroglobulinemia | Chronic Lymphocytic Leukaemia

United Kingdom
Celgene

Completed

Study to Evaluate Safety and Tolerability of Iberdomide (CC-220) in Participants With Kidney Impairment Compared to Participants With Normal Kidney Function

Renal Insufficiency

United States
Celgene

Completed

A Pilot Study of CC-220 to Treat Systemic Lupus Erythematosus.

Systemic Lupus Erythematosus

United States
Enzon Pharmaceuticals, Inc.

Completed

A Phase I, Study to Evaluate the Safety and Tolerability of Intravenous EZN-2208 in Patients With Advanced Solid Tumors or Lymphoma (EZN-2208-01)

Lymphoma | Advanced Solid Tumors

United States
Medical College of Wisconsin
National Institute on Aging (NIA)

Completed

Network-Level Mechanisms for Preclinical Alzheimer's Disease Development

APOE 4

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); GlaxoSmithKline; Merck Sharp & Dohme LLC; Nova...

Completed

BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer

Lung Cancer

United States
innoVactiv Inc.

Completed

Effects of 2006-RD-05 on Salivary and Serum Immunoglobulin A (IgA) Levels in Healthy Subjects

Healthy

Canada
Sanofi Pasteur, a Sanofi Company

Completed

Phase IV Trial to Determine the Safety and Immunogenicity of the WHO Formulation of the 2006-2007 Fluzone® Vaccine

Influenza

United States

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