Search clinical trials for: metformin (Glucophage®)

Total 15712 results

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

GXR RM China BE Study (Darmstadt - Jiangsu)

Healthy

Germany
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

GXR RM (Glucophage® Extended Release Reduced Mass) 500 Milligram (mg) Korea Bioequivalence (BE) Study

Healthy

Korea, Republic of
Boehringer Ingelheim

Completed

Bioequivalence Study of Two Strengths of Two Different Metformin Tablets Administered to Healthy Male and Female Subjects

Healthy
PegBio Co., Ltd.
Covance

Completed

Dose-finding of PB-119 Administered Subcutaneously Once Weekly Versus Placebo in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)

United States
Joint Stock Company "Farmak"

Completed

Fed Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Takeda

Completed

Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.

Diabetes Mellitus

United States, Chile, Mexico, Puerto Rico
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Safety and Efficacy of Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (T2DM) and Inadequate Glycemic Control (MK-3102-011)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Omarigliptin (MK-3102) in ≥18 and <45 Year-Old Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control (MK-3102-028)

Diabetes Mellitus
Geropharm

Completed

Bioequivalence Study of Metformin 750 mg Tablets XR Versus Glucophage® Long 750 mg Tablets XR In Normal Healthy Subjects Under Fasting and Fed Conditions

Bioequivalence

Russian Federation
AstraZeneca

Completed

Bioequivalence Study of 500 mg and 1000 mg Glucophage (Metformin) Tablets in Healthy Subjects

Type 2 Diabetes Mellitus

United States
Merck KGaA, Darmstadt, Germany

Completed

Metformin Extended Release Versus Metformin Immediate Release in Subjects With Type 2 Diabetes (CONSENT)

Diabetes Mellitus, Type 2

Germany
University of Utah
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Recruiting

Metformin for Fibromyalgia Symptoms (INFORM Trial)

Fibromyalgia Syndrome

United States
Gwendolyn Sowa

Completed

Effects of Metformin on Low Back Pain

Low Back Pain

United States
James Wang
United States Department of Defense

Recruiting

Managing Chronic Tendon Pain by Metformin

Chronic Pain | Tendinopathy | Achilles Tendinopathy

United States
Chinese PLA General Hospital

Unknown

Comparison of the Effects of Repaglinide and Metformin on Glucose Excursions

Type 2 Diabetes

China
Bristol-Myers Squibb

Completed

Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa, United States, Canada, Puerto Rico, Hungary, Germany, Czechia, Poland, Romania, United Kingdom
Khyber Medical University Peshawar

Completed

Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome

Pakistan
Hua Medicine Limited

Completed

Drug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DM

Type 2 Diabetes Mellitus

United States
AstraZeneca

Terminated

Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM

Type 2 Diabetes Mellitus

United States
Duke University

Terminated

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) (NAFLD)

Fatty Liver

United States
Merck Sharp & Dohme LLC

Completed

Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Combination Therapy With Glimepiride and Metformin (MK-3102-022)

Type 2 Diabetes Mellitus
National Institute on Aging (NIA)

Completed

The Effects of Metformin on Blood Vessel Structure and Function

Hyperglycemia | Hypertension | Obesity | Hypercholesterolemia

United States
Mylan Pharmaceuticals Inc

Completed

Food Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR 500 mg

Healthy

United States
Teva Pharmaceuticals USA

Completed

Metformin ER 750 mg Tablets, Fed

Healthy

Canada
Teva Pharmaceuticals USA

Completed

Metformin ER 750 mg Tablets, Fasting

Healthy

Canada
Mylan Pharmaceuticals Inc

Completed

Fasting BE Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

Healthy

United States
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Co-Administration of Sitagliptin and Metformin in China (MK-0431-121)

Type 2 Diabetes Mellitus
National Cancer Institute (NCI)

Active, not recruiting

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

Hyperplasia | Oral Cavity Carcinoma | Oral Leukoplakia | Erythroplakia

United States, Canada
University Medical Centre Ljubljana

Completed

PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome

Obesity | PCOS

Slovenia
Jagiellonian University

Active, not recruiting

dataBase for Analysis of Rectal Cancer Oncological Results (BARO)

Rectal Cancer | Lymph Node Metastases | Metformin | Overall Survival | Disease-free Survival

Poland
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metformin Hydrochloride ER Tablets 750 mg and Glucophage® XR Tablets 750 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

Healthy

United States
Merck KGaA, Darmstadt, Germany

Completed

Glucophage® Extended Release (XR) 750 Milligram (mg) Indonesia Bioequivalence (BE) Study

Healthy

Indonesia
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Metformin

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Metformin

United States
Allergan

Completed

Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy Subjects

Healthy

United States
Milton S. Hershey Medical Center

Terminated

Metformin for the Treatment of Premature Pubarche in Girls

Premature Pubarche

United States
Joint Stock Company "Farmak"

Completed

Fed Bioequivalence Study of 2 Metformin 500 mg Prolongued Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Wroclaw Medical University

Completed

Metformin and Its Impact on the Substances Associated With NO Production in Prediabetes Patients.

PreDiabetes | Impaired Glucose Tolerance (IGT) | Impaired Fasting Glucose (IFG)

Poland
Joint Stock Company "Farmak"

Completed

Fasting Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fasting Condition

Fasting

India
Oregon Health and Science University

Completed

Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome

United States
UFUOMA MILLER FAKPOR

Completed

BLADDER CANCER SCREENING AMONG DIABETIC PATIENTS

Diabetes | Bladder Cancer

Ghana
University of Kansas Medical Center

Recruiting

Effects of Metformin on Airway Ion Channel Dysfunction in Cystic Fibrosis-related Diabetes

Cystic Fibrosis | Cystic Fibrosis-related Diabetes

United States
VA Office of Research and Development
Oregon Health and Science University

Completed

Metformin and Muscle in Insulin-resistant Older Veterans (M&M)

Prediabetes

United States
University of California, San Francisco

Completed

Impact of Genetics on Metformin Pharmacokinetics

Other Conditions That May Be A Focus of Clinical Attention

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fasting Condition

Healthy

India
Medical University of Vienna
Merck Serono GmbH, Germany

Active, not recruiting

Metformin Therapy in Non-diabetic AAA Patients (MetAAA)

Abdominal Aortic Aneurysm

Austria
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance

Metabolic Syndrome | Insulin Resistance | Type 2 Diabetes

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fed Condition

Healthy

India
National Cancer Institute (NCI)

Completed

Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI

Obesity | Colorectal Cancer | Adenomatous Polyp

Canada, United States

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