Search clinical trials for: metformin (Glucophage®)

Total 15770 results

Promomed, LLC

Completed

Efficacy and Safety of Sibutramin-containing Drugs in Patient With Alimentary Obesity

Obesity

Russian Federation
University of Texas Southwestern Medical Center

Completed

Preservation of Beta-cell Function in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
University Medical Centre Ljubljana

Completed

The Effect of a Liraglutide on IVF in Obese PCOS

Obesity | Polycystic Ovary Syndrome | Infertility, Female
University of California, San Francisco
National Institutes of Health (NIH); National Institute of General Medical...

Completed

Drug-drug Interaction Study With Metformin and Imatinib

Healthy

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Impact of Metformin on Peripheral Arterial Calcification in Type 1 Diabetes (IMPACT-1D)

Type 1 Diabetes | Peripheral Arterial Calcification

France
Boehringer Ingelheim

Completed

A Study in Healthy Humans to Assess the Relative Bioavailability of One Fixed-dose Combination Tablet Empagliflozin/Metformin Versus Jardiance® Tablet and Glifage® Tablet Administered Together (InPedILD®)

Healthy

Brazil
Takeda

Completed

Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus. (SPLENDOR)

Diabetes Mellitus

Italy
Takeda

Completed

Phase 1 Bioavailability Study of SYR-322MET

Healthy Volunteers
Shanghai 6th People's Hospital

Unknown

the Efficacy of Acarbose and Metformin on Blood Glucose Fluctuation When Combined With Premix Insulin (CGMS)

Type 2 Diabetes

China
Beni-Suef University

Not yet recruiting

Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome

Polycystic Ovary

Egypt
Columbia University
Astellas Pharma Inc; Susan G. Komen Breast Cancer Foundation

Completed

Study of Erlotinib and Metformin in Triple Negative Breast Cancer

Breast Cancer

United States
xiaolong zhao
Shanghai Zhongshan Hospital; Second Affiliated Hospital of Soochow University; Taizhou Hospital and other collaborators

Unknown

Effect on Beta Cell Function and Glycaemic Control After Insulin and Exenatide Sequential Therapy (T2DMRS)

Type 2 Diabetes

China
University Medical Centre Ljubljana

Completed

Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss

Polycystic Ovary Syndrome | Body Weight
Samuel Lunenfeld Research Institute, Mount Sinai...
Merck Sharp & Dohme LLC

Completed

Beta-Cell Function and Sitagliptin Trial (BEST) (BEST)

Type 2 Diabetes Mellitus

Canada
Takeda

Completed

Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus. (PIOcomb)

Diabetes Mellitus

Germany
University of Edinburgh

Not yet recruiting

Molecular Effects of Aspirin & Metformin on Colonic Epithelium

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma
Xiaojun Chen
Zhejiang Cancer Hospital; Fudan University; Shanghai 6th People's Hospital; Shanghai...

Completed

Megestrol Acetate Plus Metformin to Megestrol Acetate in Patients With Endometrial Atypical Hyperplasia or Early Stage Endometrial Adenocarcinoma

Endometrial Adenocarcinoma | Endometrial Atypical Hyperplasia

China
Services Institute of Medical Sciences, Pakistan

Completed

Comparison of Metformin and Insulin for Management of Gestational Diabetes Mellitus

Gestational Diabetes Mellitus in Pregnancy

Pakistan
Dan Zandberg

Recruiting

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Melanoma | Hepatocellular Carcinoma | NSCLC | Gastric Adenocarcinoma | Esophageal Adenocarcinoma | Urothelial Cancer | HNSCC | Microsatellite Instability-High Solid Malignant Tumor

United States
AstraZeneca

Completed

Bioequivalence Study of 2.5-mg Saxagliptin and 500-mg Glucophage in Tablets and a Fixed-dose Combination Tablet in Healthy Participants

Type 2 Diabetes Mellitus

United States
Dawn Smiley MD

Completed

Ketosis-Prone Diabetes Mellitus (KPDM): Metformin Versus Sitagliptin Treatment

Hyperglycemia | Ketosis Prone Diabetes | Diabetes Ketoacidosis

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Sitagliptin Addition During Metformin Up-titration (MK-0431-848)

Type 2 Diabetes Mellitus
AstraZeneca
Bristol-Myers Squibb

Completed

Efficacy and Safety of Dapagliflozin in Combination With Glimepiride (a Sulphonylurea) in Type 2 Diabetes Patients

Type 2 Diabetes

Czech Republic, Korea, Republic of, Hungary, Poland, Ukraine, Philippines, Thailand
University of Pisa
Merck Sharp & Dohme LLC

Completed

Metformin and Sitagliptin in Women With Previous Gestational Diabetes

Pre-diabetes

Italy
AstraZeneca

Completed

Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XR

Diabetes Mellitus

United States
RISE Study Group
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

RISE Adult Medication Study (RISE Adult)

Type 2 Diabetes | Prediabetes

United States
Shanghai 10th People's Hospital

Completed

SGLT2 Inhibitors in Patients With PCOS (PCOS)

Polycystic Ovary Syndrome

China
University of Campinas, Brazil

Terminated

Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer (NEOMETRE)

Adenocarcinoma | Carcinoma | Rectal Neoplasms

Brazil
University of New Mexico

Completed

A Double-Blind, Placebo-Controlled Trial of Anti-Aging, Pro-Autophagy Effects of Metformin in Adults With Prediabetes

PreDiabetes | Aging

United States
University of Louisville
James Graham Brown Cancer Center

Withdrawn

Study of Dabrafenib, Trametinib and Metformin for Melanoma Patients

Melanoma

United States
Sun Yat-sen University

Completed

Efficacy Study of Liraglutide vs.Sitagliptin vs. Glargine on Liver Fat in T2DM Subjects (LIGHT-ON)

Non-alcoholic Fatty Liver Disease

China
Takeda

Completed

Efficacy of Pioglitazone/Metformin Combination Therapy in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia.

Diabetes Mellitus | Dyslipidemias

Germany
German University in Cairo

Recruiting

Drug Repurposing Using Metformin for Improving the Therapeutic Outcome in Multiple Sclerosis Patients

Multiple Sclerosis

Egypt
Gilead Sciences

Completed

Single Cohort 4-period Study to Assess Pharmacokinetics of Metformin Alone and in Combination With Ranolazine

Type 2 Diabetes Mellitus

United States
Takeda

Completed

Comparative Study to Evaluate Efficacy and Safety When Metformin Hydrochloride 500 mg Once Daily is Added on to SYR-322 25 mg in Type 2 Diabetic Patients With Inadequate Glycemic Control Despite Treatment With SYR-322 25 mg in Addition to Diet and Exercise Therapy

Type 2 Diabetes Mellitus

Japan
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Metformin Combined With Chemotherapy for Pancreatic Cancer (GEM)

Metastatic Pancreatic Cancer | Locally Advanced Pancreatic Cancer

Netherlands
AstraZeneca

Completed

Evaluate the Efficacy and Safety of Saxagliptin in Combination With Metformin IR Compared to Saxagliptin Monotherapy and to Metformin IR Monotherapy in Drug Naive Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control

Type 2 Diabetes Mellitus

China
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes (MANATEE-T1D)

Cardiovascular Diseases | Type 1 Diabetes | Diabetic Kidney Disease | Endothelial Dysfunction | Insulin Sensitivity

United States
Woman's
Merck Sharp & Dohme LLC

Completed

Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM

Disorder of Glucose Regulation

United States
Takeda

Completed

Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Australia, Brazil, Chile, Guatemala, India, Mexico, New Zealand, Peru, South Africa, Czech Republic, Germany, Hungary, Netherlands, Poland, United Kingdom, Argentina
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy

Glioblastoma | Gliosarcoma | Supratentorial Glioblastoma

United States
Sanofi

Completed

Efficacy and Safety of the Fixed Dose Combination of Glimepiride+Metformin in Type 2 Diabetic Patients Inadequately Controlled (LEGEND)

Type 2 Diabetes Mellitus

Lebanon, Russian Federation, Ukraine
Teva Pharmaceuticals USA

Completed

Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fed

Healthy

Canada
Avera McKennan Hospital & University Health Center

Terminated

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Breast Cancer | Breast Tumors

United States
Takeda
Eli Lilly and Company

Completed

Observational Study to Assess Glycosylated Hemoglobin Changes After 6 Months of Treatment With Pioglitazone.

Diabetes Mellitus

Denmark, Iceland, Norway, Sweden
Mansoura University

Completed

Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome

Egypt
Teva Pharmaceuticals USA

Completed

Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fasting

Healthy

Canada
Fox Chase Cancer Center
National Cancer Institute (NCI)

Withdrawn

Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Serous Cystadenocarcinoma | Recurrent Ovarian Epithelial Cancer | Recurrent Primary Peritoneal Cavity Cancer | Recurrent Ovarian Germ Cell Tumor | Ovarian Papillary Serous Carcinoma | Recurrent Fallopian Tube Cancer

United States
Northwestern University

Terminated

Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
Gynecologic Oncology Associates
University of North Carolina, Chapel Hill

Unknown

Study of Paclitaxel, Carboplatin and Oral Metformin in the Treatment of Advanced Stage Ovarian Carcinoma

Epithelial Ovarian Carcinoma

United States

Search clinical trials for: metformin (Glucophage®)

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