Search clinical trials for: Metformin DR

Total 2330 results

Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.

Carcinoma, Non-Small-Cell Lung | Lung Adenocarcinoma

United States
Kayseri Education and Research Hospital

Completed

Apoptotic Signaling Pathways in Rats With Endometrial Hyperplasia

Apoptotic Signal Pathways in Endometrial Hyperplasia

Turkey
Fondazione IRCCS Istituto Nazionale dei Tumori,...
University of Milan; European Institute of Oncology; IFOM, The FIRC Institute...

Active, not recruiting

Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer (BREAKFAST)

Triple-negative Breast Cancer

Italy
National Cancer Institute (NCI)
NCIC Clinical Trials Group; Southwest Oncology Group; Cancer and Leukemia Group...

Completed

Sunitinib Malate or Sorafenib Tosylate in Treating Patients With Kidney Cancer That Was Removed By Surgery (ASSURE)

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v7 | Stage II Renal Cell Cancer AJCC v7 | Stage I Renal Cell Cancer AJCC v6 and v7

United States, Canada, Puerto Rico
Amgen

Completed

To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib.

Advanced Solid Tumors
Genentech, Inc.

Active, not recruiting

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

Breast Cancer | Solid Tumor

United States, France, Spain, United Kingdom, Canada
Boston Medical Center

Terminated

Methadone and Medication Abortion

Pain | Medical Abortion

United States
Health Clinics Limited

Withdrawn

Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer (METRICS)

Cancer | Overall Survival

United Kingdom
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Drug-Drug Interaction Study of Evobrutinib and Transporter Substrates

Healthy

Germany
Ain Shams University
Misr University for Science and Technology

Completed

Efficacy of Vit E in PCOS Resistant to Clomiphene Citrate

Clomiphene Citrate Resistant Polycystic Ovary Syndrome

Egypt
Bausch Health Americas, Inc.
Valeant Russia, LLC

Completed

Safety and Efficacy of Neuromultivit in Treatment of Vertebrogenic Radiculopathy (NMRUS)

Vertebrogenic Radiculopathy L5, S1

Russian Federation
NYU Langone Health

Completed

NSAID vs. Narcotics

Multimodal Analgesia | Nonsteroidal Anti-inflammatory Drugs

United States
Reckitt Benckiser Healthcare (UK) Limited
Premier Research Group plc

Completed

Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars

Stomatognathic Diseases | Tooth Diseases | Tooth, Impacted

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Erasmus Medical Center

Terminated

Sorafenib PK in Patients With Advanced HCC and Child-Pugh B (SORBE)

BCLC Stage C HCC | CP-B Liver Cirrhosis

Netherlands
Dr. Reddy's Laboratories Limited

Completed

Bioequivalency Study of Ibuprofen 200 mg and Pseudoephedrine HCL 30 mg Tablets of Dr. Reddy's Under Fasting Conditions

Healthy

India
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)

Type 2 Diabetes Mellitus
Pfizer

Completed

Assessment of the Analgesic Effects of PF-06273340 in Healthy Volunteers Using Evoked Pain Endpoints

Healthy

Netherlands
Assiut University

Completed

Letrozole or Combined Clomiphene Citrate Metformin as a First Line Treatment in Women With Polycystic Ovarian Syndrome (PCO)

Polycystic Ovary Syndrome

Egypt
Reata, a wholly owned subsidiary of Biogen
Covance

Completed

A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone

Healthy Adult Subjects

United States
Janssen Research & Development, LLC

Completed

A Study of Lazertinib (JNJ-73841937) in Healthy Participants

Healthy

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)

Type 2 Diabetes Mellitus
Orexigen Therapeutics, Inc

Completed

Study to Evaluate the Effect of Naltrexone and Bupropion Combination on the Pharmacokinetics of Metformin in Healthy Participants

Healthy Subjects
MedSIR
Novartis

Active, not recruiting

Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients (METALLICA)

Breast Cancer

Spain
University of Minnesota
University of Colorado, Denver; Northwestern University; Olive View-UCLA Education... and other collaborators

Completed

COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)

Covid19 | SARS-CoV Infection

United States
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)

Type 2 Diabetes Mellitus
Instituto Brasileiro de Osteopatia

Completed

Analysis of the Effects of the Osteopathic Manipulative Treatment in Carriers of Temporomandibular Disorders

Temporomandibular Disorder

Brazil
Baylor College of Medicine

Enrolling by invitation

Post-operative Pain Management in Children With Supracondylar Humerus Fractures

Supracondylar Humerus Fracture

United States
H. Lee Moffitt Cancer Center and Research Institute
Pediatric Cancer Foundation

Completed

Metformin in Children With Relapsed or Refractory Solid Tumors

Solid Tumors | Primary Brain Tumors

United States
ARKAY Therapeutics
Albany Medical College

Not yet recruiting

Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients (RESILIENCE)

Obesity | Arthritis | Type 2 Diabetes | High Blood Pressure

United States
Haukeland University Hospital

Completed

IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC (IMPACT)

Ovarian Cancer

Norway
Altimmune, Inc.

Completed

ALT-801 DDI Study in Healthy Volunteers

NASH - Nonalcoholic Steatohepatitis

Australia
Peking Union Medical College Hospital
Chinese Academy of Sciences

Unknown

Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic Agents

Type2 Diabetes Mellitus

China
Eli Lilly and Company

Terminated

A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM) (IMPERIUM)

Diabetes Mellitus, Type 2

United States, Puerto Rico, Germany, United Kingdom, Austria
Bristol-Myers Squibb

Completed

A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants

Healthy Participants

United States
Weill Cornell Medical College in Qatar
University of Hull; Hamad Medical Corporation; Sidra Medical and Research Center

Active, not recruiting

HbA1c Variability in Type II Diabetes

Diabetes Mellitus Type 2

Qatar
Boehringer Ingelheim

Completed

DIA_CENTRAL:T2D Treatment Pattern in Central Europe

Diabetes Mellitus, Type 2

Bulgaria, Czechia, Hungary, Poland, Russian Federation
Sanofi

Completed

Comparison of Two Treatment Regimens in Patients With Type 2 Diabetes After Short-term Intensive Insulin Therapy (SWITCH)

Type 2 Diabetes Mellitus

China
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study To Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).

Type 2 Diabetes Mellitus
Montefiore Medical Center

Completed

Comparative Efficacy of 4 Oral Analgesics

Pain

United States
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer

Metastatic Breast Cancer

United States
Wake Forest University Health Sciences
Carolinas Trauma Network Research Group; Charlotte, Houston, Milwaukee Prehospital...

Completed

IN Sub-Dissociative Ketamine vs IN Fentanyl

Bone Fracture

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)

Diabetes Mellitus, Type 2
Merck Sharp & Dohme LLC
Pfizer

Completed

Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

Type 2 Diabetes Mellitus
Seoul National University Hospital
Seoul National University Bundang Hospital; Korea University Guro Hospital; Gangnam... and other collaborators

Completed

Comparative Effectiveness Study for Surgery vs. Non-Surgery in Patients With Low Back Pain (CES_SNS_LBP)

Low Back Pain

Korea, Republic of
St. Jude Children's Research Hospital
Ohio State University; Arog Pharmaceuticals, Inc.

Completed

Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

Acute Myeloid Leukemia

United States
Novartis

Completed

To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies

Type 2 Diabetes Mellitus | Impaired Glucose Tolerance

United States, Canada, Finland, Australia, Germany, India, Italy
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Incretin-based Drugs and Pancreatic Cancer

Diabetes Mellitus, Type 2

Canada
Changhai Hospital

Recruiting

Endotherapy for Painless Chronic Pancreatitis (EACH)

Abdominal Pain | Pancreatitis, Chronic | Exocrine Pancreatic Insufficiency | Cholangiopancreatography, Endoscopic Retrograde

China
Washington State University
National Center for Complementary and Integrative Health (NCCIH)

Completed

Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach

Interaction Drug Food

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Neoadjuvant Chemotherapy Followed by Radiation Therapy and Gemcitabine/Sorafenib/Vorinostat in Pancreatic Cancer

Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States

Search clinical trials for: Metformin DR

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Trinidad & Tobago

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations