Search clinical trials for: Metformin Hydrochloride 500 MG

Total 3597 results

The Hospital for Sick Children
University of Alberta; University of Waterloo

Terminated

Metformin Treatment in Infants After Perinatal Brain Injury

Premature Birth | Hypoxic Ischemic Encephalopathy of Newborn

Canada
NHS Tayside
University of Southern Denmark; Helmholtz Zentrum München; University of Dundee

Completed

Pharmacokinetics of Metformin Intolerance (POMI)

Diabetes Mellitus, Type 2 | Metformin Adverse Reaction
Takeda

Completed

Human Pharmacology Trial of Calcium-vitamin D3 Tablet in Healthy Participants (Osteopro)

Vitamin D Deficiency | Calcium Deficiency

Germany
Teva Branded Pharmaceutical Products R&D, Inc.
FHI 360

Completed

Study to Evaluate Suppression of Ovulation and Pharmacokinetics of Medroxyprogesterone Acetate Following Administration of TV-46046 in Women With Ovulatory Cycle

Pregnancy | Contraception

United States
Atabay Kimya Sanayi Ticaret A.S.
Novagenix Bioanalytical Drug R&D Center; Farmagen Ar-Ge Biyot. Ltd. Sti

Unknown

The Bioequivalence Study of Umifenovir 200 mg Capsul (ATABAY, Turkey) Under Fasting Conditions (Umifenovir)

Bioequivalence

Turkey
University Medical Centre Ljubljana

Completed

PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome

Obesity | PCOS

Slovenia
HaEmek Medical Center, Israel

Withdrawn

To Compare the Efficacy of I.V 200 mg Iron Sucrose and 500 mg Iron Sucrose to Treat Anemia in Pregnancy

Pregnancy
GlaxoSmithKline

Completed

A Study to Evaluate the Effects of SB-751689 or rhPTH(1-34) on Excretion of Calcium and Phosphate in Women

Osteoporosis

United States
National Eye Institute (NEI)

Recruiting

Oral Metformin for Treatment of ABCA4 Retinopathy

Retinal Degeneration | Stargardt Disease | ABCA4 Retinopathy | Retinal Dystrophy

United States
Woman's
AstraZeneca

Completed

Dapagliflozin and Metformin,Alone and in Combination, in Overweight/Obese Prior GDM Women (DAPA-GDM)

Diabetes Prevention in Women After GDM Who Are at High-risk

United States
University of California, Davis
National Cancer Institute (NCI); Astellas Pharma Inc; Medivation, Inc.

Active, not recruiting

Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer

Prostate Cancer

United States
Hanmi Pharmaceutical Company Limited

Completed

Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 500mg and Rosuvastatin 10mg

Diabetes Mellitus

Korea, Republic of
Torrent Pharmaceuticals Limited

Completed

Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fed Conditions

Healthy

India
Anna Stanhewicz, PhD

Not yet recruiting

Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

Gestational Diabetes
University of Kansas Medical Center

Recruiting

Effects of Metformin on Airway Ion Channel Dysfunction in Cystic Fibrosis-related Diabetes

Cystic Fibrosis | Cystic Fibrosis-related Diabetes

United States
Chong Kun Dang Pharmaceutical

Unknown

Clinical Trial to Investigate the Pharmacokinetics and Safety of CKD-393

T2DM (Type 2 Diabetes Mellitus)

Korea, Republic of
Christian Medical College and Hospital, Ludhiana...
All India Institute of Medical Sciences, New Delhi; Indian Council of Medical... and other collaborators

Recruiting

Indian Trial of Tranexamic Acid in Spontaneous Intracerebral Haemorrhage

Intracerebral Hemorrhagic Stroke

India
Novartis Pharmaceuticals

Completed

Study of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inclisiran in Chinese Participants With Elevated Serum LDL-C (ORION-14)

Hyperlipidemia

China
Ardea Biosciences, Inc.

Completed

Antacid Interaction Study

Healthy

United States
Cytokinetics
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Pharmacodynamic Study of CK-2017357 in Patients With Generalized Myasthenia Gravis

Myasthenia Gravis

United States
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary

United States
Janssen Research & Development, LLC

Withdrawn

A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate

Active Rheumatoid Arthritis; Rheumatoid Arthritis
Hamamatsu University

Completed

Comparison of Vonoprazan-based Dual and Triple Therapies for H. Pylori Eradication

Gastritis Associated With Helicobacter Pylori

Japan
Laboratorios Silanes S.A. de C.V.

Suspended

Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 Diabetes (COMETII)

Type 2 Diabetes

Mexico
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability of Orfiril Long 500 mg Prolonged-Release Minitablets and Ergenyl Chrono 500 mg Prolonged-Release Tablets

Multiple Drug Use

Canada
Columbia University

Recruiting

Metformin in Heart Failure Without Diabetes (Met-HeFT)

Heart Failure

United States
Canadian Cancer Trials Group
National Cancer Institute (NCI); ETOP IBCSG Partners Foundation; ICR-CTSU

Completed

A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer

Breast Cancer

United States, Canada, Switzerland, United Kingdom
Shenzhen People's Hospital

Unknown

Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes

Type 1 Diabetes Mellitus | Metformin

China
Boehringer Ingelheim
Eli Lilly and Company

Completed

Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets

Healthy

United States
University of North Carolina, Chapel Hill
Northwestern University; GlaxoSmithKline; University of Utah; MNGI Digestive Health...

Completed

Mepo for Eosinophilic Esophagitis (EoE) Study

Eosinophilic Esophagitis | EoE

United States
Laboratorios Silanes S.A. de C.V.
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Unknown

Efficacy Study of Metformin Glycinate on Postprandial Lipemia

Type 2 Diabetes

Mexico
Teva Pharmaceuticals USA

Completed

Cefadroxil 500 mg Capsules in Normal Healthy Non-Smoking Male and Female Subjects.

Healthy

United States, Canada
Sandoz

Completed

A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions

Type 2 Diabetes
Boehringer Ingelheim

Completed

Bioavailability of 2 Different Nevirapine Extended Release Formulations Compared to Viramune® in HIV-1 Infected Subjects

HIV Infections
Medical University of Bialystok
Medical Research Agency, Poland

Not yet recruiting

Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility (METIN)

Infertility, Female
National University of Ireland, Galway, Ireland
Health Research Board, Ireland; University Hospital of Limerick; University College... and other collaborators

Completed

A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects (EMERGE)

Gestational Diabetes

Ireland
National Cancer Institute (NCI)

Completed

Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI

Obesity | Colorectal Cancer | Adenomatous Polyp

Canada, United States
MedImmune LLC

Completed

A Phase 2a Study to Evaluate the Safety and Tolerability of Benralizumab (MEDI-563) in Adults With Asthma

Asthma

United States
MedPacto, Inc.

Recruiting

Vactosertib in Combination With Pembrolizumab for PD-L1 Positive Non-small Cell Lung Cancer (NSCLC) Subjects

Carcinoma, Non-Small-Cell Lung

Korea, Republic of
Cognition Therapeutics
National Institute on Aging (NIA)

Completed

Effect of CT1812 Treatment on Brain Synaptic Density

Alzheimer Disease

United States
Agios Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Mitapivat (AG-348) in Healthy Adult Participants

Healthy Volunteers

United States
University of Florida

Recruiting

Can Cranberry Juice Enhance the Cognition Accuracy and Alleviate Negative Mental Consequences During Multitasking?

Motor Activity | Cognitive Symptom | Stress Response | Mental Stress | Physiological Stress | Multitasking Behavior

United States
Dong-A ST Co., Ltd.

Completed

A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers

Type 2 Diabetes Mellitus

Korea, Republic of
Shire

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Oral Dose of Maribavir Administered in Healthy Japanese Participants Compared With Matched, Healthy, Non-Hispanic, Caucasian Participants and to Assess Dose-Proportionality of 3 Doses of Maribavir in Japanese Participants

Healthy Volunteers

United States
AstraZeneca

Completed

AZD5069 Neutrophil Function Study

Chemokine Receptor 2 (CXCR2) Antagonist

United Kingdom
Janssen-Cilag International NV

Completed

A Single Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-42165279 in Healthy Male Participants

Healthy Volunteers | Pharmacokinetics

Belgium
University Hospital, Toulouse

Terminated

Evaluation of the Entresto Effect on Sympathic Nervous System in Patient With Heart Failure (B2AN-SNS)

Heart Failure

France
Fundacion para la Formacion e Investigacion Sanitarias...

Completed

Gestational Treatment With Ursodeoxycholic Acid Compared to Placebo to Reduce Severity of Gestational Diabetes Mellitus Diagnosed at 24-28 Weeks' Gestation (GUARDS)

Gestational Diabetes

Spain
Teva Pharmaceuticals USA

Completed

Cefadroxil 500 mg Capsules Under Fasting Conditions

Healthy

United States, Canada
Teva Pharmaceuticals USA

Completed

Cefprozil 500 mg Tablets Under Fasting Conditions

Healthy

United States

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