Search clinical trials for: metformin and liraglutide

Total 272206 results

Novo Nordisk A/S

Completed

The Effect of Liraglutide Adjunct to Insulin on Glucagon Response to Hypoglycaemia in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Austria
University of Campinas, Brazil

Unknown

Influence of Liraglutide, a GLP-1 Receptor Agonist, on Brown Adipose Tissue (BAT) Activity in Humans (i-LAB)

Obesity | Type 2 Diabetes Mellitus
Tina Vilsboll

Completed

The Effects of Physical Training and GLP-1 Receptor Agonist Liraglutide Treatment in Patients With Type 2 Diabetes

Type 2 Diabetes

Denmark
Novo Nordisk A/S

Completed

A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus. (DUAL™ I Japan)

Diabetes Mellitus, Type 2 | Diabetes

Japan
Fasa University of Medical Sciences
Shiraz University of Medical Sciences

Completed

Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study

Polycystic Ovary Syndrome

Iran, Islamic Republic of
Shionogi

Completed

Study to Assess Safety and Pharmacokinetics of Double-Blind S-707106 Alone and in Combination With Open-Label Metformin in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Novo Nordisk A/S

Completed

Safety and Tolerability of Insulin Degludec/Liraglutide (A3) in Healthy Subjects

Healthy | Diabetes

Germany
University of Virginia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Recruiting

Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome (ZQL008)

Metabolic Syndrome

United States
Novo Nordisk A/S

Completed

Safety and Tolerability of Liraglutide in Healthy Volunteers and Subjects With Type 2 Diabetes

Healthy | Diabetes Mellitus, Type 2 | Diabetes

United Kingdom
RWTH Aachen University
Novo Nordisk A/S

Withdrawn

Effect of Liraglutide on the Metabolic Profile in Patients With Type 2 Diabetes and Cardiovascular Disease (Lirabolic)

Cardiovascular Diseases | Type 2 Diabetes

Germany
Novo Nordisk A/S

Completed

A Study of the Effectiveness of Xultophy® (Insulin Degludec/Liraglutide) in an Adult Real-world Population With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2 | Diabetes

Austria, Germany, United Kingdom, Sweden, Switzerland
Novo Nordisk A/S

Completed

Effect of Liraglutide on the Beta-cell Responsiveness in Subjects With Type 2 Diabetes Compared to a Healthy Control Group

Diabetes Mellitus, Type 2 | Diabetes

United States
University of Manitoba
Novo Nordisk A/S

Terminated

Study of Liraglutide in Individuals With Type 2 Diabetes Using Insulin (SAIL)

Type 2 Diabetes

Canada
ikfe-CRO GmbH
Novo Nordisk A/S; IKFE Institute for Clinical Research and Development

Completed

Impact of Liraglutide on Endothelial Function and Microvascular Blood Flow in Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Germany
Imperial College London

Withdrawn

Liraglutide on Decreasing Parenteral Support in Short Bowel Patients (SLIPS) (SLIPS)

Short Bowel Syndrome

United Kingdom
Novo Nordisk A/S

Completed

A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and Liraglutide

Diabetes Mellitus, Type 2 | Diabetes

India, Italy, Spain, Austria, Finland, Hungary, Turkey, France, United Kingdom, Switzerland, Bulgaria, Germany, South Africa, Former Serbia and Montenegro
Novo Nordisk A/S

Completed

The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment Intensification

Diabetes Mellitus, Type 2 | Diabetes

United States, Israel, Italy, United Kingdom, France, Serbia, Germany, South Africa, Canada, Ukraine, United Arab Emirates
Novo Nordisk A/S

Completed

Investigate Safety, Tolerability and Pharmacokinetics for Single Doses of NNC9204-0530 Alone and in Combination With Liraglutide in Overweight to Obese But Otherwise Healthy Male Subjects

Obesity | Metabolism and Nutrition Disorder

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes (LIRA-LIXI™)

Diabetes Mellitus, Type 2 | Diabetes

United Kingdom, France, Finland, Germany, Hungary, Latvia, Lithuania, Italy, Czech Republic
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

Human Bioequivalence Test of Liraglutide Injection

Type 2 Diabetes

China
Novo Nordisk A/S

Withdrawn

Non-interventional, Post Marketing Surveillance Study of Xultophy™ (Insulin Degludec/Liraglutide) to Evaluate Long Term Safety and Efficacy in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in India

Diabetes Mellitus, Type 2 | Diabetes
Novo Nordisk A/S

Completed

A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration Algorithms (DUAL™ VI)

Diabetes Mellitus, Type 2 | Diabetes

United States, Slovakia, Canada, Austria, Hungary, Serbia, Russian Federation, Bulgaria, Czechia
Novo Nordisk A/S

Completed

Effect of Liraglutide on Pulsatile Insulin Secretion in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Denmark
Novo Nordisk A/S

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Liraglutide in Healthy Japanese Volunteers

Diabetes Mellitus, Type 2 | Diabetes

Japan
University of Aarhus
Novo Nordisk A/S; University of Copenhagen

Completed

Effects of Liraglutide on Kidney Function in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Denmark
University of Miami
Novo Nordisk A/S

Recruiting

Liraglutide Effects on Epicardial Fat Inflammatory Genes

Coronary Artery Disease | Type2 Diabetes

United States
NuSirt Biopharma

Completed

An Extension Protocol to Evaluate Dose Comparisons of Leucine-Metformin Combinations in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of MP-513 in Combination With Metformin in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Poland, United Kingdom, Germany, Romania, Hungary, Denmark, Lithuania
University Hospital, Basel, Switzerland

Completed

L-citrulline and Metformin in Becker's Muscular Dystrophy

Becker's Muscular Dystrophy (BMD)

Switzerland
Novo Nordisk A/S

Completed

Dual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 Diabetes (DUAL™ I)

Diabetes Mellitus, Type 2 | Diabetes

United States, India, Italy, Mexico, Russian Federation, Slovakia, Spain, Canada, Taiwan, Finland, Hungary, Malaysia, South Africa, United Kingdom, Germany, Australia, Thailand, Ireland, Puerto Rico, Singapore
Turku University Hospital

Active, not recruiting

Liraglutide in the Prevention of Type 2 Diabetes After Gestational Diabetes (Liragest)

Gestational Diabetes

Finland
Novo Nordisk A/S

Completed

Effect and Safety of Liraglutide 3.0 mg as an Adjunct to Intensive Behaviour Therapy for Obesity in a Non-specialist Setting (SCALE™ IBT)

Obesity | Metabolism and Nutrition Disorder

United States
Merck Sharp & Dohme LLC

Completed

Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403)

Diabetes Mellitus, Type 2
Novo Nordisk A/S

Completed

Effect of Liraglutide on Weight and Appetite in Obese Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Denmark
Novo Nordisk A/S

Completed

Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or Obesity (STEP 8)

Obesity | Overweight

United States
Jens Faber

Completed

LIPT - Liraglutide in Polycystic Ovary Syndrome (LIPT)

Cardiovascular Disease | Polycystic Ovary Syndrome

Denmark
Stanford University

Completed

Liraglutide and a Calorie Restricted Diet Augments Weight Loss and Decreases Risk of Type 2 Diabetes and CVD.

Older Adults | Pre-diabetes
Novo Nordisk A/S

Completed

Safety, Tolerability and Pharmacokinetics of Liraglutide-depot in Healthy Subjects

Healthy | Diabetes Mellitus, Type 2 | Diabetes

United States
Novo Nordisk A/S

Completed

Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Safety and Tolerability of Liraglutide in Healthy Male Volunteers

Healthy | Diabetes

United Kingdom
Novo Nordisk A/S

Completed

Effect of Liraglutide on Glucose Profiles and Gastric Emptying in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Denmark
Emirates Health Services (EHS)

Recruiting

POSE2.0 With GLP-1 Agonist for Obesity Management

Obesity

United Arab Emirates
Aalborg University Hospital
Novo Nordisk A/S

Completed

Treatment of Diabetic Neuropathy With Liraglutide (TODINELI)

Diabetes Mellitus, Type 1 | Type 1 Diabetes Mellitus

Denmark
Novo Nordisk A/S

Completed

The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin Therapy (DUAL™IV)

Diabetes Mellitus, Type 2 | Diabetes

United States, India, Israel, Puerto Rico, Germany, Turkey, Canada, Bulgaria
Indiana University
Novo Nordisk A/S

Completed

Cooperation of Insulin and GLP-1 on Myocardial Glucose Uptake

Type 2 Diabetes

United States
Bristol-Myers Squibb

Completed

Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa, United States, Canada, Puerto Rico, Hungary, Germany, Czechia, Poland, Romania, United Kingdom
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Alone

Diabetes Mellitus Type 2

United States, Mexico, Argentina
Hadassah Medical Organization

Withdrawn

Open-label Crossover Metformin Gum Versus Tablet in Healthy Volunteers

Healthy

Israel
Charles University, Czech Republic

Completed

Effect of Metformin on Exercise-induced Lipolysis

Diabetes Mellitus, Type 2

Czechia
Geropharm

Completed

Bioequivalence Study of Metformin 750 mg Tablets XR Versus Glucophage® Long 750 mg Tablets XR In Normal Healthy Subjects Under Fasting and Fed Conditions

Bioequivalence

Russian Federation

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