Search clinical trials for: Methotrexate

Total 1486 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Total-Body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia

Leukemia

United States, Germany
National Research Center for Hematology, Russia

Recruiting

RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSL

Primary CNS Lymphoma

Russian Federation
St. Jude Children's Research Hospital
AbbVie; Gateway for Cancer Research; Karyopharm Therapeutics Inc

Recruiting

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Refractory Acute Myeloid Leukemia | Acute Myeloid Leukemia, in Relapse | Acute Leukemia of Ambiguous Lineage in Relapse | Refractory Acute Leukemia of Ambiguous Lineage

United States
University of Nebraska

Completed

Triple III Comparison of Leflunomide Alone Versus Two DMARD Combinations in the Treatment of Rheumatoid Arthritis

Rheumatoid Arthritis

United States
University of California, San Diego
National Cancer Institute (NCI)

Terminated

Allogeneic Stem Cell Transplant After ATG, High-Dose Melphalan, and Fludarabine for Patients With Breast Cancer

Breast Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Genentech, Inc.; Biologics, Inc.

Completed

Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Lymphoma | Leukemia

United States
Therapeutic Advances in Childhood Leukemia Consortium
Ambit Biosciences Corporation

Completed

AC220 for Children With Relapsed/Refractory ALL or AML

Lymphoblastic Leukemia, Acute, Childhood | Myelogenous Leukemia, Acute, Childhood

United States
Sanofi
Regeneron Pharmaceuticals

Completed

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

Rheumatoid Arthritis

United States, Argentina, Belgium, Brazil, Czechia, Estonia, Finland, Hungary, Israel, Italy, Mexico, Netherlands, Poland, Romania, Russian Federation, Spain, Sweden, United Kingdom, Norway
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Institute of Allergy and Infectious...

Terminated

Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases

Myelodysplastic Syndromes | Leukemia | Graft Versus Host Disease

United States
HaEmek Medical Center, Israel

Terminated

Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast Cancer

Chemotherapy | Breast Cancer, Metastatic

Israel
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma

Sarcoma | Cardiac Toxicity

United States
Dutch Childhood Oncology Group

Completed

Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia

Leukemia

United States, United Kingdom, Belgium, Italy, Germany, Austria, Ireland, Netherlands, France, Sweden, Czech Republic
National Cancer Institute (NCI)
Children's Cancer Group

Completed

506U78 in Treating Patients With Refractory Hematologic Cancer

Recurrent Childhood Acute Lymphoblastic Leukemia | T-cell Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Lymphoblastic Lymphoma

United States
University of Vermont
Dartmouth-Hitchcock Medical Center; Maimonides Medical Center

Unknown

Low Dose Chemotherapy With Aspirin in Patients With Breast Cancer After Neoadjuvant Chemotherapy

Breast Cancer

United States
Taiho Pharmaceutical Co., Ltd.

Completed

The Comparative Trial of UFT + TAM With CMF + TAM in Adjuvant Therapy for Breast Cancer (CUBC)

Breast Cancer

Japan
Temple University

Completed

Bone Marrow Transplant Plus Cyclophosphamide and Total-Body Irradiation in Treating Patients With Hematologic Cancer

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Diseases

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Gemtuzumab Ozogamicin, Fludarabine, and Total-body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia

United States
National Cancer Institute (NCI)

Completed

A Pilot Trial of Sequential Chemotherapy With Antimetabolite Induction, High-Dose Alkylating Agent Consolidation With Peripheral Blood Progenitor Cell Support, and Intensification With Paclitaxel and Doxorubicin for Patients With High-Risk Breast Cancer

Breast Cancer | Breast Neoplasms

United States
Fairview University Medical Center

Unknown

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Hemophagocytic Lymphohistiocytosis | Graft Versus Host Disease | Chediak-Higashi Syndrome | Virus-Associated Hemophagocytic Syndrome | X-Linked Lymphoproliferative Syndrome | Familial Erythrophagocytic Lymphohistiocytosis

United States
University of Chicago

Recruiting

Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

Acute Lymphoblastic Leukemia | Lymphoblastic Leukemia | ph+ Acute Lymphoblastic Leukemia

United States
PETHEMA Foundation

Completed

Treatment of Acute Lymphoblastic Leukemia HIGH RISK BCR / ABL NEGATIVE IN ADULTS

Acute Lymphoblastic Leukemia

Spain
Region Västerbotten
Karolinska University Hospital; Uppsala University; Umeå University; Vastra Gotaland... and other collaborators

Recruiting

Methotrexate in Patients With Early Rheumatoid Arthritis (MTXRA)

Rheumatoid Arthritis

Sweden
Nishtar Medical University

Completed

Medical Treatment in Ectopic Tubal Pregnancy

Ectopic Pregnancy

Pakistan
Shahid Beheshti University of Medical Sciences

Unknown

Repeated Methotrexate for Proliferative Vitreoretinopathy Grade C

Proliferative Vitreoretinopathy

Iran, Islamic Republic of
Hoffmann-La Roche

Completed

Study to Describe Real World Drug Retention Rate of the Tocilizumab at One Year

Rheumatoid Arthritis

France
University of Leeds
Hoffmann-La Roche

Completed

Tocilizumab REMission in Early RA (TREMERA)

Rheumatoid Arthritis

United Kingdom
Juan Carlos Nieto
Nordic Pharma SAS

Unknown

Rheumatoid Arthritis Response to Methotrexate

Rheumatoid Arthritis

Spain
Karolinska University Hospital

Completed

Skin Disease and Pulmonary Mortality After Transplantation

Acute GVH Disease | Pulmonary Mortality
Amgen

Terminated

Effects of Denosumab on the Pharmacokinetics of Etanercept

Rheumatoid Arthritis | Osteoporosis | Osteopenia | Postmenopausal

United States
Forsight Vision4

Terminated

Safety and Preliminary Efficacy Study of V404 PDS in Uveitis

Uveitis, Posterior | Uveitis, Intermediate

United States
Isofol Medical AB

Completed

A Retrospective Non-intervention Study to Characterize FOlate Rescue Treatment in Osteosarcoma Patients Treated With HDMTX (FORTO)

Osteosarcoma

Norway, Sweden, Hungary, Poland
medac GmbH
PPD

Completed

Bioavailability in Patient With Psoriasis: Metoject Prefilled Pen

Psoriasis

United States
Federal University of São Paulo

Completed

Effectiveness Of Expectant Management In The Tubal Ectopic Pregnancy

Ectopic Pregnancy

Brazil
Meir Medical Center

Unknown

BHCG Level in Day 4,7, in Comparison to Day 10 as an Indicator for Treatment Success (BHCG)

Ectopic Pregnancy

Israel
Institute of Child Health

Unknown

Community-Based Interventions for Infant Health in Nepal

Child Mortality

United Kingdom
Michael Pulsipher, MD

Active, not recruiting

Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia

Severe Aplastic Anemia

United States
Genentech, Inc.
Roche Pharma AG

Terminated

A Study to Evaluate Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus (BEGIN) (BEGIN)

Systemic Lupus Erythematosus
University of Texas Southwestern Medical Center

Terminated

Study Of Two Non-Myeloablative Stem Cell Transplant Strategies For Low-Grade Lymphoma And CLL

Lymphoma | Leukemia

United States, Canada
St. Jude Children's Research Hospital

Terminated

Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States
Merck Sharp & Dohme LLC
AESCA Pharma GmbH

Terminated

Induction of Remission in RA Patients at Low Disease Activity by Additional Infliximab Therapy (Study P04644AM1) (TERMINATED)

Rheumatoid Arthritis
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Chemotherapy Alone in Treating Women With Stage IV Breast Cancer

Breast Cancer

United States
Children's Hospital of Philadelphia

Terminated

Chemotherapy With or Without Total-Body Irradiation Prior to Bone Marrow Transplantation in Treating Children With Acute Lymphoblastic Leukemia

Leukemia

United States, Canada
Amgen

Recruiting

A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout

Gout

United States
University of Texas Southwestern Medical Center
assertio Therapeutics, Inc

Not yet recruiting

Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease

Urolithiasis | Post Operative Pain | Ureter Calculi | Stent Complication

United States
Peking Union Medical College Hospital

Recruiting

Intermediate Dose of IV MTX as CNS Prophylaxis for High Risk DLBCL (NHL-011)

Diffuse Large B Cell Lymphoma | Central Nervous System Lymphoma

China
Stanford University

Withdrawn

Methotrexate For The Prevention and Treatment of Proliferative Vitreoretinopathy in Pediatric Patients (SIGHT)

Proliferative Vitreoretinopathy

United States
National Eye Institute (NEI)

Terminated

Treatment of Non-infectious Intermediate and Posterior Uveitis Associated Macular Edema With Intravitreal Methotrexate (MEXX)

Non-infectious Intermediate and Posterior Uveitis

United States
Philogen S.p.A.

Completed

Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Italy
Seoul National University Hospital

Unknown

2-week dc of MTX and Influenza Vaccination in RA (2 wk MTX)

Rheumatoid Arthritis | Influenza | Methotrexate

Korea, Republic of
Royal Marsden NHS Foundation Trust

Terminated

Methotrexate in Metastatic Colorectal Cancer With MSH2 Deficiency (MESH)

Advanced Colorectal Cancer

United Kingdom

Search clinical trials for: Methotrexate

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