Search clinical trials for: Mineralocorticoid Receptor Antagonists

Total 37356 results

National Institute of Diabetes and Digestive and...

Completed

Improving Outcomes in Patients With Kidney Disease Due to Diabetes

Hypertension | Diabetes | Kidney Disease

United States
Assistance Publique - Hôpitaux de Paris
Société de Dermatologie Française

Completed

Interest of Topical Spironolactone's Administration to Prevent Corticoid-induced Epidermal Atrophy (SPIREPI)

Cutaneous Atrophy Due to Corticosteroids

France
Brigham and Women's Hospital
Gilead Sciences

Terminated

The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study

Pulmonary Arterial Hypertension

United States
University of Pennsylvania

Recruiting

Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne

Acne

United States
Pfizer

Completed

A Single Dose Study Of Antimineralocorticoid Activity Of PF-03882845 In Healthy Volunteers

Healthy Volunteers

United States
The George Institute

Not yet recruiting

The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect (CAPTIVATE)

Chronic Kidney Diseases
Actelion

Withdrawn

Correlation of LONGterm Wrist ACTigraphy Recorded Physical Performance & 6-minute Walk Distance in Patients With Pulmonary Arterial Hypertension (LONGACT)

Pulmonary Arterial Hypertension
Insud Pharma
Chemo Research

Recruiting

LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women

Bone Loss | Change in Bone Mineral Density

United States
Actinium Pharmaceuticals

Recruiting

Venetoclax and Lintuzumab-Ac225 in AML Patients

Acute Myeloid Leukemia | Relapsed Adult AML

United States
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI); Beth Israel Deaconess Medical...

Active, not recruiting

Hypoglycemia and Autonomic Nervous System Function-B (HypoANS-B)

Healthy | Hypoglycemia

United States
Federico II University

Completed

Eplerenone Versus PDT: Comparative Study by OCTA

Central Serous Chorioretinopathy
Estetra
PRA Health Sciences

Completed

E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - EU/Russia Study

Contraception

Belgium
Sandoz

Completed

Comparative Bioavailability Study of Eplerenone 50 mg Tablets Under Fasting Conditions

Hypertension
Eunice Kennedy Shriver National Institute of Child...

Completed

Treatment of Boys With Precocious Puberty

Precocious Puberty

United States
Brigham and Women's Hospital
National Institutes of Health (NIH)

Completed

Aldosterone and Vascular Disease in Diabetes Mellitus

Diabetes Mellitus | Albuminuria | Endothelial Dysfunction

United States
Kevin Flanigan
Muscular Dystrophy Association

Terminated

Spironolactone Versus Prednisolone in DMD

Muscular Dystrophy, Duchenne

United States
Darnitsa Pharmaceutical Company
ACDIMA Biocenter

Completed

Bioequivalence Study of Test and Reference 50 mg Eplerenone Film-coated Tablets in Healthy Volunteers

Healthy Subjects | Bioequivalence

Jordan
AstraZeneca

Completed

A Study to Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects

Healthy Subjects | Pharmacodynamics

United Kingdom
Indiana Institute for Medical Research

Recruiting

Spironolactone in CKD Enabled by Chlorthalidone: PILOT (SPICE PILOT)

Renal Insufficiency | Chronic Hypertension

United States
Estetra
PRA Health Sciences

Completed

E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - United States/Canada Study

Contraception

United States, Canada
Sandoz

Completed

Comparative Bioavailability Study of Eplerenone 50 mg Tablets Under Fed Conditions

Hypertension
Tottori University Hospital

Completed

Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure

Chronic Stable Heart Failure
University Hospital, Angers

Terminated

Hemodynamic Effects of Chronic Administration of Spironolactone and/or Propranolol in Alcoholic Cirrhotic Patients

Alcoholic Cirrhosis
Hvidovre University Hospital

Unknown

Effect of Betablocker or Aldosterone Antagonist Therapy on Patients With Liver Cirrhosis (PEKASYS)

Liver Cirrhosis | Portal Hypertension

Denmark
Shanghai Jiao Tong University School of Medicine

Recruiting

The Comparison Between Spironolactone and Indapamide Monotherapy or in Combination With Amlodipine to Reduce the Risk of Heart Failure (SIRRHF)

Hypertension

China
The University of Texas Health Science Center at...

Withdrawn

High-Dose Aldactone for Treatment of Diuretic Resistant Heart Failure

Heart Failure

United States
Nantes University Hospital

Completed

Randomized Double-blind Study on the Benefit of Spironolactone for Treating Acne of Adult Woman. (FASCE)

Acne Vulgaris

France
Vanderbilt University
American Heart Association

Completed

Tissue Sodium in Pre-hypertensive Patients

Hypertension

United States
Centre Oscar Lambret
National Cancer Institute, France

Terminated

Evaluation of the Efficacy of Diuretics for Symptomatic Malignant Ascites Episodes in Advanced Stage of Cancer (DIASC)

Cancer

France
Institute of Cardiology, Warsaw, Poland

Unknown

Clinical Efficacy of Potassium Canrenoate in Sinus Rhythm Restoration Among Patients With Atrial Fibrillation. (CANREN-AF)

Atrial Fibrillation, Paroxysmal
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome

Polycystic Ovary Syndrome | Acanthosis Nigricans
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Role of Mineralocorticoid Receptor in Diabetic Cardiovascular Disease

Type 2 Diabetes Mellitus | Vascular Disease

United States
Cairo University

Completed

The Effect of Oral Contraceptives on Women Balance

Joint Stabilioty

Egypt
Bayer

Completed

Safety Study of Ethinylestradiol/Drospirenone in Dysmenorrhea

Dysmenorrhea

Japan
Tottori University Hospital

Completed

Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF)

Chronic Stable Heart Failure
Suzhou Kintor Pharmaceutical Inc,

Completed

The Safety and Tolerability of GT0918 in Subjects With mHSPC and mCRPC

Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) | Metastatic Castrate Resistant Prostate Cancer (mCRPC)

United States
Suzhou Kintor Pharmaceutical Inc,

Completed

Safety, Tolerability, and PK of GT0918 (Proxalutamide) in Subjects With Metastatic Castrate Prostate Cancer

Metastatic Castrate Resistant Prostate Cancer (mCRPC)

United States
Bayer

Completed

Study to Compare How the Body Distributes and Excretes the Drugs Jivi (BAY 94-9027) and Adynovi in Patients With Severe Hemophilia A (Bleeding Disorder Resulting From a Lack of Blood Clotting Factor VIII)

Hemophilia A

Bulgaria
Alere San Diego

Terminated

HF Assessment With BNP in the Home: Part II (HABIT-II)

Heart Failure

United States, Netherlands, New Zealand, United Kingdom, Ireland, Sweden
Universidade Gama Filho
Instituto Nacional de Cardiologia de Laranjeiras

Completed

Renin-angiotensin-aldosterone System Polymorphisms in Resistant Hypertension and Adverse Cardiovascular Events (GENHART)

Myocardial Infarction | Stroke | Hypertension Resistant to Conventional Therapy | Systemic Arterial Hypertension

Brazil
Brigham and Women's Hospital

Recruiting

Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

Hypertension | Left Ventricular Hypertrophy

United States
Instituto do Coracao
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Unknown

Resistant Hypertension Optimal Treatment (ReHOT)

Hypertension

Brazil
Baylor Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Impact of Medical and Surgical Therapy on Functional Mitral Regurgitation

Heart Diseases | Cardiovascular Diseases | Coronary Disease

United States
Biogen

Terminated

Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency (POSEIDON)

Heart Failure | Renal Insufficiency

United States
VA Office of Research and Development
Baylor College of Medicine

Completed

Biomarker Guided Therapies in Stage A/B Heart Failure

Hypertension | Cardiovascular Disease | Diabetes

United States
Ottawa Heart Institute Research Corporation

Completed

Spironolactone Therapy in Chronic Stable Right HF Trial (STAR-HF)

Pulmonary Arterial Hypertension | Pulmonary Hypertension, Primary, 4 | Chronic Right-Sided Heart Failure | Pulmonary Hypertension, Primary, 2 | Pulmonary Hypertension, Primary, 3 | Cardiomyopathy Right Ventricular

Canada
Bayer

Completed

Low-dose Hormone Therapy for Relief of Vasomotor Symptoms

Vasomotor Symptoms | Hot Flashes

United States
Bayer

Completed

Study to Investigate the Natriuretic Effects, Safety, Tolerability and Pharmacokinetics of BAY94-8862

Clinical Pharmacology

Germany
Vanderbilt University

Terminated

Defining Strategies for Improving Endothelial and Fibrinolytic Dysfunction in Obesity

Metabolic Syndrome X

United States
Biolab Sanus Farmaceutica

Withdrawn

Pharmacokinetics of Eplerenone Tablet

Healthy Volunteers

Search clinical trials for: Mineralocorticoid Receptor Antagonists

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