Search clinical trials for: Moxifloxacin and Cobicistat

Total 271389 results

GlaxoSmithKline

Completed

Tafenoquine Thorough QTc Study in Healthy Subjects

Malaria, Vivax

United States
Shanghai Public Health Clinical Center

Unknown

Efficacy and Safety of Darunavir and Cobicistat for Treatment of COVID-19 (DC-COVID-19)

Coronavirus | Pneumonia, Pneumocystis

China
AiCuris Anti-infective Cures AG

Completed

Thorough QT/QTc of Pritelivir in Healthy Subjects

HSV Infection

United Kingdom
St Stephens Aids Trust
Bristol-Myers Squibb

Completed

SSAT067 PK of Atazanavir/Cobicistat and Darunavir/Cobicistat

HIV

United Kingdom
Hamad Medical Corporation

Completed

Darunavir/Cobicistat vs. Lopinavir/Ritonavir in COVID-19 Pneumonia in Qatar (DOLCI)

Pneumonia | COVID | Coronavirus

Qatar
Hoffmann-La Roche

Completed

Study to Investigate the Effect of Balovaptan on the QTC Interval in Healthy Subjects

Healthy Volunteers

United States
Janssen Research & Development, LLC

Completed

A Study of Darunavir in the Presence of Cobicistat When Administered as a Fixed Dose Combination Under Fed Conditions

Healthy

Belgium
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Pharmacokinetics (PK) of Darunavir (DRV) and Cobicistat (COBI) After a Single Oral Administration of Darunavir/Cobicistat Fixed-Dose Combination in Healthy Japanese Adult Participants

Healthy

Japan
A.O. Ospedale Papa Giovanni XXIII
San Raffaele University Hospital, Italy

Unknown

RPV+DRV/Cobi Dual Therapy in Subjects With HIV Controlled Infection (PROBE2)

HIV Infection

Italy
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
ViiV Healthcare

Completed

EFFICACY AND SAFETY OF A SIMPLIFICATION STRATEGY BASED ON DOLUTEGRAVIR AND DARUNAVIR / COBICISTAT VS OPTIMIZED TREATMENT IN SUPPRESSED HIV-1-INFECTED PATIENTS CARRYING ARCHIVED MULTIDRUG RESISTANCE MUTATIONS

HIV-1 Infection

Spain
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Clinical Trial to Evaluate Drug-drug Interactions Between Darunavir/Cobicistat and Etravirine in Hiv- Infected Patients

HIV-1 Infection

Spain
Syndax Pharmaceuticals

Recruiting

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation (AUGMENT-101)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Acute Leukemia of Ambiguous Lineage | Mixed Phenotype Acute Leukemia | Mixed Lineage Acute Leukemia

United States, Israel, Spain, Australia, Netherlands, Germany, Canada, France, Italy, Lithuania
University of California, San Diego
Gilead Sciences; University at Buffalo

Completed

Elvitegravir (EVG) Cerebrospinal Fluid (CSF) Pharmacokinetics in HIV-Infected Individuals

HIV

United States
Massachusetts General Hospital
Gilead Sciences; Brigham and Women's Hospital

Completed

Advanced Neuroimaging Evaluation of the Central Nervous System Biological Changes Associated With Efavirenz Therapy and Switch to an Elvitegravir-based Regimen

HIV Disease

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Electrophysiological Effects of Potential QT Prolonging Drugs

Pharmacokinetics | Pharmacodynamics | Drug-induced QT Prolongation

United States
National Institutes of Health Clinical Center (CC)

Completed

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers

Healthy Volunteers

United States
Therapeutic Concepts
Janssen Scientific Affairs, LLC

Unknown

Open Label, Pilot Study of Darunavir Boosted by Cobicistat in Combination With Rilpivirine to Treat HIV+ Naïve Subjects (PREZENT)

HIV Positive

United States
Janssen Scientific Affairs, LLC

Completed

A Single-arm, Open-label, Study to Assess the Pharmacokinetics of Darunavir and Ritonavir, Darunavir and Cobicistat, Etravirine, and Rilpivirine in HIV-1 Infected Pregnant Women

HIV Infections | Pregnancy | HIV

United States, Puerto Rico
Janssen Sciences Ireland UC

Completed

Relative Bioavailability and Food Effect for Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Fixed Dose Combination

Healthy

Belgium
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Clinical Trial to Evaluate Pharmacological Interactions Between γ-hydroxybutyrate (GHB) and Cobicistat (GHB_Cobi)

HIV | Pharmacokinetic Interactions

Spain
Stanford University
University of Colorado, Denver; Janssen Scientific Affairs, LLC

Withdrawn

Darunavir/Cobicistat and Dolutegravir to Maintain Virologic Suppression and Reduce NRTI-associated Toxicity (TMC114HIV2030)

HIV/AIDS

United States
St Stephens Aids Trust
ViiV Healthcare

Completed

SSAT061: PK of DTG and EVT/COBI in Healthy Volunteers

HIV

United Kingdom
GlaxoSmithKline

Completed

A Study to Evaluate the Effect of Intravenous Zanamivir on Cardiac Conduction in Healthy Volunteers

Influenza, Human

United States
Emory University
Centers for Disease Control and Prevention

Completed

Body Compartment Pharmacokinetics of Anti-retroviral Agents That May be Considered for Future On-demand Peri-exposure HIV Prophylaxis Regimens

HIV/AIDS

United States
Foundation for Liver Research

Withdrawn

Pancreatic Enzyme Suppletion in Pancreatic Cancer (EPC)

Adenocarcinoma of the Pancreas | Normal Pancreatic Exocrine Function

Netherlands
University of California, San Francisco

Recruiting

Antibiotic Resistance In Eye Surgeries (ARIES)

Antibiotic Resistance | Ocular Surface Microbiome | Gut Resistome

United States
Janssen R&D Ireland

Completed

A Study to Assess the Bioequivalence of Darunavir When Co-Administrated With Cobicistat Under Fed and Fasted Conditions

Healthy Participants

Belgium
The Crofoot Research Center, Inc.
Janssen Scientific Affairs, LLC

Completed

Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART) (ReSTART)

HIV-1-infection

United States
University of Washington
Gilead Sciences; Clinique des Maladies Infectieuses Ibrahima DIOP Mar/CRCF,...

Completed

An Open Label Trial of Stribild for Antiretroviral (ARV)-naïve HIV-2 Infected Adults in Dakar, Senegal (Stribild HIV-2)

HIV-2 Infection

Senegal
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

A Study to Define the ECG Effects of Lixivaptan Compared to Placebo and Moxifloxacin in Healthy Adult Men and Women: A Thorough ECG Study

Healthy

United States
Universidade Federal de Pernambuco

Completed

Evaluation of Macular Changes After Intracameral Moxifloxacin for Prevention of Endophthalmitis

Cataract | Endophthalmitis | Macula Edema

Brazil
Heidelberg University
Bayer

Completed

Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy (ACDC)

Acute Cholecystitis

Germany
University of Karachi
Center for Bioequivalence Studies and Clinical Research; SAMI Pharmaceutical...

Completed

Bioequivalence Study of Mofest® 400mg (Moxifloxacin) Tablet With Avelox® 400mg (Moxifloxacin) Tablet in Healthy Pakistani Subjects (BE)

Healthy Individuals | Bioequivalence Study

Pakistan
Tetraphase Pharmaceuticals, Inc.

Completed

A Thorough QT/QTc Study to Evaluate the Effects of an Intravenous Infusion of Eravacycline (TP-434) on Cardiac Repolarization

Normal Healthy Subjects
Facultad Nacional de Salud Publica
Universidad de Antioquia

Completed

Adjunctive Systemic Administration of Moxifloxacin in the Treatment of Aggressive Periodontitis

Aggressive Periodontitis

Colombia
Lawson Health Research Institute
St. Joseph's Healthcare Foundation

Completed

Determining the Effect of Antibiotic Drop Prophylaxis on the Conjunctival Flora

Age-Related Macular Degeneration

Canada
Pfizer

Completed

Phase 1 Thorough QT (TQT) Study in Young Healthy Volunteers (TQT)

Fibromyalgia

Belgium
Tibotec BVBA
Vertex Pharmaceuticals Incorporated

Completed

VX-950-TiDP24-C136 - A Trial to Evaluate the Effect of Telaprevir (TVR) on the Results of Electrocardiograms (Electric Recording of the Heart) in Healthy Volunteers

Hepatitis C
Bristol-Myers Squibb

Completed

Bioequivalence Study of Individual Atazanavir and Cobicistat Compared With Atazanavir in Fixed-dose Combination With Cobicistat (Atazanavir)

Human Immunodeficiency Virus Type 1 (HIV-1)

United States
Jazz Pharmaceuticals

Completed

Sativex Thorough QT/QTc Study

Effects of Sativex on ECG

Canada
Pfizer

Completed

A Study to Investigate the Effects of Sisunatovir on QTc Interval in Healthy Adult Participants.

Healthy

United States
Mitsubishi Tanabe Pharma America Inc.

Completed

Study to Evaluate the Effect of a Single Oral Dose of MT-7117 on the QT/QTc Interval in Healthy Subjects

Healthy Subjects

United States
Centre for the AIDS Programme of Research in South...

Completed

Improving Retreatment Success (IMPRESS) (IMPRESS)

Recurrent Tuberculosis

South Africa
University of Cologne

Completed

Moxifloxacin in the Prevention of Bacteremia After High-dose Chemotherapy and Transplantation of Peripheral Stem Cells (MoxiProph)

Multiple Myeloma | Hodgkin Disease | Bacteremia | Non-Hodgkin Lymphoma

Germany
Bausch Health Americas, Inc.

Completed

Prevention of Travelers' Diarrhea in Subjects Traveling Outside the U.S.

Diarrhea

United States
ViiV Healthcare
Pfizer

Completed

THE EFFECT OF CYP3A5 GENOTYPE ON THE PHARMACOKINETICS OF MARAVIROC

Healthy Subjects

United States
University Hospital, Ghent

Completed

Pharmacokinetic Evaluation of Moxifloxacin IV to Enteral Switch Therapy in Intensive Care Patients

Pneumonia

Belgium
Turku University Hospital
Oulu University Hospital; Kuopio University Hospital; Seinajoki Central Hospital and other collaborators

Not yet recruiting

Oral Antibiotic Outpatient Therapy vs. Placebo in the Treatment of Uncomplicated Acute Appendicitis (APPAC IV)

Uncomplicated Acute Appendicitis

Finland
Radboud University Medical Center

Completed

Pharmacokinetic Interaction Study in Indonesian Tuberculosis Patients Indonesia

Tuberculosis

Indonesia
Eli Lilly and Company
Incyte Corporation

Completed

A Study of LY3009104 in Healthy Participants

Healthy Participants

United States

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