Search clinical trials for: N-803 and BCG

Total 4828 results

ImmunityBio, Inc.

Active, not recruiting

QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer

Bladder Cancer

United States
Altor BioScience

Terminated

PK Sub-Study of QUILT-3.032 (CA ALT-803-01-16) and of QUILT-2.005 (CA ALT-803-01-14)

Pharmacokinetics

United States
ImmunityBio, Inc.

Recruiting

A Study of Intravesical BCG in Combination With ALT-803 in Patients With Non-Muscle Invasive Bladder Cancer

Non-muscle Invasive Bladder Cancer

United States
Pontificia Universidad Catolica de Chile
Millennium Institute on Immunology and Immunotherapy; Comisión Nacional de...

Completed

A Study to Assess Safety, Tolerability and Immunogenicity of the Live Attenuated hRSV Vaccine rBCG-N-hRSV (EVA-VRS01)

Respiratory Syncytial Virus Infections

Chile
Masonic Cancer Center, University of Minnesota

Completed

Relapse Prophylaxis With N-803 for AML and MDS Pts Following Allo HSCT

Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML)

United States
Thai Red Cross AIDS Research Centre
Walter Reed Army Institute of Research (WRAIR); Henry M. Jackson Foundation...

Recruiting

Reducing HIV Persistence in Lymph Nodes by Interleukin-15 (IL-15) Receptor Super-agonist (N-803) in Acute HIV Infection

HIV/AIDS

Thailand
ImmunityBio, Inc.

Active, not recruiting

QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Merkel Cell Carcinoma | Microsatellite Instability | Mismatch Repair Deficiency

United States
ImmunityBio, Inc.

Recruiting

Single Center Study Of N-803 Stimulation On Expansion, Enrichment, Proliferation Of Natural Killer Cells Collected By Apheresis

Healthy Subjects

United States
University of Surrey
Royal Surrey County Hospital NHS Foundation Trust; Ashford and St. Peter's...

Withdrawn

Testing the Accuracy of a Personal Heart Rhythm Monitor to Detect Prolonged Paroxysmal Atrial Fibrillation

Stroke | Paroxysmal Atrial Fibrillation

United Kingdom
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Effect of N-803 on B Cell Follicles in Antiretroviral Treated HIV Disease

HIV Infections | Hiv | AIDS

United States
ImmunityBio, Inc.

Active, not recruiting

Study of the Safety of Therapeutic Treatment With an Immunomodulatory Agent (N-803) in Adults With COVID-19

COVID-19

United States
National Cancer Institute (NCI)

Withdrawn

N-803 Alone or in Combination With BN-Brachyury Vaccine or Bintrafusp Alfa (M7824) for Participants With Castration Resistant Prostate Cancer

Castration Resistant Prostate Cancer

United States
University of Minnesota

Withdrawn

N-803 Combined With the Broadly Neutralizing Antibodies Plus or Minus haNK Cells for HIV

HIV Infections | HIV/AIDS | Hiv | AIDS | Aids/Hiv Problem | AIDS and Infections

United States
ImmunityBio, Inc.

Terminated

QUILT-3.009: Patients With Stage III (IIIB) or Stage (IV) Merkel Cell Carcinoma (MCC)

Stage IIIB Merkel Cell Carcinoma | Stage IV Merkel Cell Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers

Small Bowel Cancers | Colorectal Cancers

United States
National Institute of Allergy and Infectious Diseases...
ImmunityBio, Inc.; Rockefeller University

Recruiting

Safety, Tolerability, and Efficacy of IL-15 Superagonist (N-803) With and Without Combination Broadly Neutralizing Antibodies to Induce HIV-1 Control During Analytic Treatment Interruption

HIV Infection

United States
Melinta Therapeutics, LLC

Recruiting

Study to Evaluate the Safety and Tolerability of Single-Dose Intravenous (IV) Oritavancin

Acute Bacterial Skin and Skin Structure Infection

United States, Spain, Greece, Portugal, Bulgaria, Latvia, Romania, Lithuania, Poland
Washington University School of Medicine
Eli Lilly and Company; ImmunityBio, Inc.

Withdrawn

Ramucirumab, Atezolizumab and N-803 After Progression on Any Immune Checkpoint Blocker in NSCLC (RAN)

NSCLC | Non Small Cell Lung Cancer | Non-small Cell Lung Cancer | Non-small Cell Carcinoma
ImmunityBio, Inc.

Active, not recruiting

Follow up of Intravesical N-803 Plus BCG in BCG-Naive Non-Muscle Invasive Bladder Cancer (NMIBC)

Non Muscle Invasive Bladder Cancer

United States
National Cancer Institute (NCI)

Recruiting

Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)

Metastatic Colorectal Cancer

United States
Dana-Farber Cancer Institute
ImmunityBio, Inc.

Not yet recruiting

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

Ovarian Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Recurrent Ovary Cancer | Ovarian Carcinoma, Recurrent

United States
Alexion Pharmaceuticals

Completed

Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB)

Mucopolysaccharidosis IIIB

United States, United Kingdom, Spain
University of Surrey
Royal Surrey County Hospital NHS Foundation Trust

Completed

Using a Personal Heart Rhythm Monitor to Diagnose Paroxsymal Atrial Fibrillation in the Community

Stroke | Paroxysmal Atrial Fibrillation

United Kingdom
University Hospital, Grenoble
Clinical Investigation Centre for Innovative Technology Network; University... and other collaborators

Unknown

Computer-assisted Fetal Monitoring - Cardiology (SURFAO-CARDIO)

Pregnancy

France
National Cancer Institute (NCI)

Recruiting

Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome

Lynch Syndrome

United States, Puerto Rico
Bandim Health Project
University of Southern Denmark

Recruiting

Trial to Compare BCG-Bulgaria and BCG-Denmark (BCGSTRAIN IV)

Morbidity;Newborn | Non-specific Effects of Vaccines | Death, Infant | Morbidity;Infant | Death; Neonatal

Guinea-Bissau
Noorik Biopharmaceuticals AG

Terminated

A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosis

Cirrhosis | Ascites | Portal Hypertension

Spain
ImmunityBio, Inc.

Not yet recruiting

N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive Glioblastoma

Glioblastoma
Bandim Health Project
Odense University Hospital; Odense Patient Data Explorative Network; Municipality...

Completed

Using BCG to Protect Senior Citizens During the COVID-19 Pandemic

Covid19 | Immunosenescence | Vaccine Preventable Disease | Morbidity | Non-specific Effects of Vaccines | Heterologous Immunity

Denmark
Dana-Farber Cancer Institute
ImmunityBio, Inc.; Kidney Cancer Association

Not yet recruiting

A Phase 0 Pilot Study of Memory-like Natural Killer (NK) Cell Immune Therapy in Combination With N-803 in Patients With Renal Cell Carcinoma or Urothelial Carcinoma

Renal Cell Carcinoma | Urothelial Carcinoma | Renal Carcinoma

United States
MedImmune LLC

Completed

A Study to Evaluate the Safety of the Respiratory Syncytial Virus Vaccine MEDI7510 in Older Adults

Respiratory Syncytial Virus (RSV)

United States
Mendel Tuchman
University of Colorado, Denver; Children's Hospital of Philadelphia; University... and other collaborators

Terminated

Long-term Outcome of N-Carbamylglutamate Treatment in Propionic Acidemia and Methylmalonic Acidemia

Propionic Acidemia | Methylmalonic Acidemia

United States
The Leeds Teaching Hospitals NHS Trust

Completed

The Role of High Density Surface ECG in the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

Arrhythmogenic Right Ventricular Cardiomyopathy
Aptose Biosciences Inc.

Active, not recruiting

A Study of CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Aeras
University of Rochester

Completed

Leukapheresis Sampling for Immune Responses After BCG Vaccination in BCG-naïve Healthy Adults in the US

Tuberculosis
ImmunityBio, Inc.

Active, not recruiting

QUILT 2.023: A Study of N-803 in Combination With Current Standard of Care vs Standard of Care as First-Line Treatment for Patients With Stage 3 or 4 NSCLC.

Non Small Cell Lung Cancer

United States
Biofabri, S.L
South African Tuberculosis Vaccine Initiative; TuBerculosis Vaccine Initiative and other collaborators

Completed

Dose-Defining Safety and Immunogenicity Study of MTBVAC in South African Neonates (MTBVAC-03)

Tuberculosis

South Africa
Bandim Health Project
Research Center for Vitamins and Vaccines

Completed

Comparing Morbidity and Mortality Effects of Two Different Strains of BCG

Vaccine Adverse Reaction | Vaccine Reaction | Infant Mortality | Heterologous Immunity | Infant Morbidity | Trained Immunity

Guinea-Bissau
Bandim Health Project
Research Center for Vitamins and Vaccines, Statens Serum Institute

Terminated

Can Earlier BCG Vaccination Reduce Early Infant Mortality? A Randomised Trial (BCGR)

Infant Mortality | BCG

Guinea-Bissau
Glenn J. Hanna
ImmunityBio, Inc.

Recruiting

PD-L1 t-haNK, N-803 IL-15sa and Cetuximab for Recurrent, Metastatic HNSCC

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Cancer | Metastatic Head and Neck Cancer | Metastatic Head-and-neck Squamous-cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer

Gastroesophageal Junction (GEJ) Cancers | Advanced HNSCC

United States
Chengdu CoenBiotech Co., Ltd
Hunan Cancer Hospital

Completed

Clinical Study to Investigate the Safety and Tolerance of Therapeutic BCG in Postoperative Adjuvant Therapy in Subjects With Moderate to High-risk Non-muscular Invasive Bladder Cancer (NMIBC)

Non-muscular Invasive Bladder Cancer

China
ImmunityBio, Inc.

Recruiting

QUILT-3.076: Study of Autologous M-CENK in Subjects With Locally Advanced or Metastatic Solid Tumors

Metastatic Solid Tumor

United States
The University of Texas Health Science Center at...

Terminated

Intravesical BCG Administration to Patients With Invasive Bladder Cancer

Bladder Cancer

United States
University of Stellenbosch
Thrasher Research Fund

Unknown

The Effect of Bacille Calmette Guerin (BCG) Vaccination on Immune Responses in HIV-Exposed and Unexposed Infants

HIV Infections

South Africa
Murdoch Childrens Research Institute
Royal Children's Hospital; University of Melbourne; Mercy Hospital for Women,...

Active, not recruiting

Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction (MIS BAIR)

Respiratory Tract Infections | Allergy | Eczema

Australia
ImmunityBio, Inc.

Terminated

QUILT-3.063: A Study of N-803, haNK and Avelumab in Patients With Merkel Cell Carcinoma That Has Progressed After Checkpoint Therapy

Merkel Cell Carcinoma

United States
Aptose Biosciences Inc.

Active, not recruiting

A Study of CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Bandim Health Project
Radboud University Medical Center

Completed

Testing if BCG (Bacille Calmette-Guérin) Vaccination Can Induce Innate Immune Training in Adult People Above 50 Years of Age in Guinea-Bissau

Innate Immunity | Bacille Calmette-Guérin

Guinea-Bissau
National Institute of Allergy and Infectious Diseases...

Completed

BCG Vaccination Delivered Intradermally, Orally and by Combined Routes

Tuberculosis

United States

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