Search clinical trials for: Nirogacestat oral tablet

Total 13695 results

University Health Network, Toronto

Recruiting

Efficacy, Mechanisms and Safety of SGLT2 Inhibitors in Kidney Transplant Recipients (INFINITI2019)

Type 2 Diabetes | Kidney Transplant Recipients | Post-transplant Diabetes Mellitus

Canada
Weill Medical College of Cornell University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Trial of an Intervention to Improve Metformin Persistence and Adherence (TreatMet)

Tolerance | Metformin Adverse Reaction

United States
Mansoura University

Completed

Oral Prednisolone Effect on Cancer WHO Stepladder Analgesia Protocol

Steroid Anlgesia in Cancer Pain

Egypt
Hospital Universitario de Fuenlabrada
Centro Nacional de Investigaciones Oncologicas CARLOS III

Active, not recruiting

Clinical Trial to Evaluate Efficacy of 3 Types of Treatment in Patients With Pneumonia by COVID-19 (Covid19COVINIB)

COVID-19 Pneumonia

Spain
Catherine Anne Chappell
Gilead Sciences

Recruiting

Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy (STORC)

Hepatitis C, Chronic | Pregnancy; Infection

United States, Canada
University Medical Centre Ljubljana
University of Palermo

Recruiting

Semaglutide Anti-Atherosclerotic Mechanisms of Action Study in Type 2 Diabetes Patients (SAMAS)

Diabetes Mellitus, Type 2 | Atherosclerosis

Slovenia
Zydus Lifesciences Limited

Completed

Desidustat in the Treatment of Anemia in CKD (DREAM-ND)

Anemia | Chronic Kidney Disease Stage 5 | Chronic Kidney Disease Stage 3 | Chronic Kidney Disease Stage 4

India
Mahidol University
Siam Pharmaceutical Ltd.

Unknown

Linezolid for Treatment of Nontuberculous Mycobacterial Diseases

Non-tuberculous Mycobacterial Infections

Thailand
Vaxart

Completed

A Ph 2 Trial With an Oral Tableted COVID-19 Vaccine

COVID-19

United States
SynAct Pharma Aps
NBCD A/S

Completed

A Safety & Efficacy Study of Treatment With AP1189 in Rheumatoid Arthritis Patients naïve to DMARD Treatment (EXPAND)

Rheumatoid Arthritis

Moldova, Republic of
University of Massachusetts, Amherst

Withdrawn

O2 Transport and Utilization in Health and Lung Disease

Oxidative Stress | COPD | Tetrahydrobiopterin Deficiency

United States
Albireo

Completed

A Phase 2 Study of Elobixibat in Adults With NAFLD or NASH

NAFLD | NASH

United States
University of Louisville
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Pilot Study of Green Tea Extract (Polyphenon E®)in Ulcerative Colitis

Mild to Moderately Active Ulcerative Colitis

United States
Takeda

Completed

A Study to Assess the Relative Bioavailability and to Assess the Effect of Food on the Bioavailability of a TAK-648 Tablet in Healthy Participants

Healthy Volunteers

United States
Cosmo Technologies Ltd

Completed

Polyp Detection Rate After Single Oral Dose of Methylene Blue MMX Modified Release Tablets Administered to Subjects Undergoing Outpatients Colonoscopy

Polyp and Adenoma Detection During Colonoscopy
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
National Department of Health, Papua New Guinea; School of Medicine and Health...

Active, not recruiting

Repurposing Clinically Approved Drugs for Yaws With an Insight Into the Cutaneous Ulcer Disease Syndrome (Trep-AByaws) (Trep-AByaws)

Yaws | Cutaneous Ulcer

Papua New Guinea
Institut Bergonié
Novartis

Terminated

Phase III Trial Evaluating the Effectiveness of a Dose Adjustment of Imatinib Mesylate on the Molecular Response (MIM)

Leukemia, Myeloid, Chronic-Phase

France
University of Electronic Science and Technology...

Unknown

The Effects of Losartan on Social Reward

Healthy

China
University of Electronic Science and Technology...

Unknown

The Effects of Losartan on Reward Reinforcement Learning

Healthy

China
VarmX B.V.

Recruiting

Single Dose Trial of VMX-C001 in Healthy Subjects With and Without FXa Direct Oral Anticoagulant

Coagulation Disorder

Netherlands
Shanghai Zhongshan Hospital

Active, not recruiting

Remission of Type 2 Diabetes With Dapagliflozin (READ Trial) (READ)

Type 2 Diabetes

China
Saint Luke's Health System

Completed

Dapagliflozin in PRESERVED Ejection Fraction Heart Failure (PRESERVED-HF)

Chronic Heart Failure With Preserved Systolic Function

United States
University of Electronic Science and Technology...

Unknown

Losartan Effects on Emotion-memory Interaction

Healthy

China
Reckitt Benckiser Healthcare (UK) Limited
Premier Research Group plc

Completed

Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars

Pain

United States
AB Science

Recruiting

Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple Sclerosis (MAXIMS)

Progressive Multiple Sclerosis

Spain, Sweden, France, Greece, Italy, Poland, Russian Federation, Ukraine
Universitair Ziekenhuis Brussel

Recruiting

A Clinical Trial of Regorafenib in Patients With Pretreated Advanced Melanoma (RegoMel)

Melanoma Stage IV | Melanoma Stage III

Belgium
Aptose Biosciences Inc.

Recruiting

Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia (APTIVATE)

Relapsed or Refractory Acute Myeloid Leukemia

United States, Germany, Spain, Korea, Republic of, Australia, New Zealand
Zydus Therapeutics Inc.

Completed

Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis (EPICS)

Primary Biliary Cirrhosis

United States
University of Sao Paulo General Hospital

Unknown

Trimetazidine in Myocardial Injury After Percutaneous Coronary Intervention in Patients With Angina and Diabetes (Trimeta)

Diabetes Mellitus | Angina, Unstable

Brazil
Overseas Pharmaceuticals, Ltd.
GX pharma technology (beijing) Co., Ltd

Active, not recruiting

An Open Label, Balanced, Randomized, 3×3 Latin Square Design Comparing of Brivaracetam Sustained-release Tablets and Brivaracetam Tablets in the Oral Comparative Pharmacokinetic(PK) Study in Chinese Healthy Adult Subjects Under Fasting Conditions.

Partial Seizure

China
Aarhus University Hospital
Odense University Hospital; Rigshospitalet, Denmark; University of Copenhagen; Herning... and other collaborators

Recruiting

The MASTER Study (MAmmary Cancer STatin ER Positive Study)

Breast Cancer Female | Estrogen Receptor Positive Tumor

Denmark
University of Michigan Rogel Cancer Center

Withdrawn

Phase IV Multi-arm Study of CDK4/6 Pharmacokinetics in Healthy Volunteers With Known CYP3A4*22 Genotype

CYP3A4*22
University of Electronic Science and Technology...

Unknown

Losartan and Emotion Processing

Healthy

China
University of Manitoba

Recruiting

Measurement of the Hippocampal Theta Rhythm From the Outer Ear Canal

Anxiety

Canada
University of Florida

Recruiting

The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults

Pain

United States
University of Cincinnati
Procter and Gamble

Completed

Studies of COVID-19 Patients Treated With Oral Bismuth Subsalicylate (Pepto-Bismol) (SABER-C)

COVID-19 | Diarrhea

United States
Ain Shams University

Unknown

Effect of Magnesium Supplement in Early Pregnancy After ICSI

ICSI

Egypt
AstraZeneca

Completed

Relative Bioavailability Study to Assess Two Solid Formulations Compared to an Oral Solution of AZD3293 in Healthy Male and Non-Fertile Female Subjects (BA)

Healthy Volunteers | Pharmacologic Action

United States
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Effect of Probiotics Before Cesarean Section on Postoperative Recovery in Pregnant Women

Microbiota | Postoperative Recovery

China
Johns Hopkins University

Withdrawn

Docosahexaenoic Acid (DHA) Supplementation in Amblyopia

Amblyopia

United States
Third Affiliated Hospital, Sun Yat-Sen University

Completed

Origin of the Neonatal Gut Microbiota and Probiotic Intervention

Microbiota

China
University of Maryland, Baltimore

Withdrawn

Safety and Preliminary Efficacy of ANS-6637 to Reduce Drug Craving and Harm in People With Opioid Use Disorder (SEARCH)

Opioid-use Disorder
GlaxoSmithKline

Completed

GW501516 In Subjects Who Have Low Level Of High-Density Lipoprotein Cholesterol

Dyslipidaemia | Dyslipidaemias

Germany, Estonia, Belgium, France, Netherlands, Denmark, Portugal, Norway, Sweden, Lithuania, Finland
Jennifer Keiser
Centre Suisse de Recherches Scientifiques en Cote d'Ivoire

Completed

Efficacy and Safety of MOX/ALB Co-administration

Hookworm Infections | Ascariasis | Trichuriasis

Côte D'Ivoire
Enteris BioPharma Inc.
Syneos Health

Completed

A Study of Pharmacokinetic/Pharmacodynamic Profile of Orally Administered Leuprolide in Healthy Female Volunteers

Endometriosis

Canada
GlaxoSmithKline

Completed

Drug Interactions From Simultaneous Administration Of Metformin And GSK189075 To Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

Mexico
Beijing Tiantan Hospital
NeuroDawn Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Sarecycline in Patients With Acute Ischemic Stroke After Reperfusion Therapy (ESPRIT)

Ischemic Stroke, Acute

China
Takeda

Completed

Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male Participants

Healthy Volunteers

United States
Emory University

Recruiting

Opioid-Free Orthopaedics

Pain | Pain, Postoperative

United States
Ohio State University

Completed

Utilization of Hepatitis C Positive Kidneys in Negative Recipients

Hepatitis C | HCV | Kidney Transplant

United States

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