Search clinical trials for: Nusinersen Sodium Injection

Total 19330 results

Biogen

Recruiting

Observational, Postmarketing Surveillance Study of Spinraza Injection (Nusinersen Sodium) (STANDARD)

Muscular Atrophy, Spinal

Korea, Republic of
Biogen

Completed

Non-Interventional, Postmarketing Surveillance Study of Nusinersen Sodium Injection (PANDA)

Muscular Atrophy, Spinal

China
First Affiliated Hospital of Fujian Medical University
Peking Union Medical College Hospital; Fujian Medical University Union Hospital

Recruiting

Antisense Oligonucleotide for Spinal Muscular Atrophy

Spinal Muscular Atrophy

China
University Medical Centre Ljubljana

Recruiting

Hyperkinetic Movements in Patients With Disease of Motor Neurons and Their Response to Treatment With Nusinersen

Tremor | SMA | MND (Motor Neurone DIsease) | Involuntary Movements

Slovenia
Biogen

Active, not recruiting

Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy (DEVOTE)

Muscular Atrophy, Spinal

China, United States, Netherlands, Spain, Korea, Republic of, Taiwan, Australia, Canada, Chile, Saudi Arabia, Poland, Israel, Brazil, Russian Federation, Hungary, Japan, United Kingdom, Italy, Germany, Estonia, Greece, Mexico, Colombia and more
University Medical Centre Ljubljana

Completed

Metabolomics of Children With SMA

Spinal Muscular Atrophy

Slovenia
Northwell Health

Completed

Effect of Nusinersen on Adults With Spinal Muscular Atrophy

Adult Spinal Muscular Atrophy

United States
Biogen

Enrolling by invitation

Extension Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy Who Previously Participated in a Study With Nusinersen (ONWARD)

Muscular Atrophy, Spinal

United States, Spain, Taiwan, Chile, Saudi Arabia, Brazil, Russian Federation, Mexico, Germany, Estonia, Japan, Canada, Colombia, Lebanon, Poland, Italy, China
Ohio State University
Biogen; Cure SMA

Completed

Adults With SMA Treated With Nusinersen

Spinal Muscular Atrophy

United States
NYU Langone Health
Winthrop University Hospital

Withdrawn

Pulmonary Function Test Changes and Respiratory Muscle Strength Trends in Spinal Muscular Atrophy Patients Receiving Nusinersen Treatments

Spinal Muscular Atrophy

United States
Hospital Israelita Albert Einstein
Ministry of Health, Brazil

Completed

Characterization of the Clinical-epidemiological Profile of Patients With SMA5q Types II and III: Observational Study

Spinal Muscular Atrophy

Brazil
Biogen

Active, not recruiting

A Study of Nusinersen Among Participants With Spinal Muscular Atrophy Who Received Onasemnogene Abeparvovec (RESPOND)

Muscular Atrophy, Spinal

United States, Spain, Germany, Italy, Israel
Biogen

No longer available

Expanded Access Program (EAP) for Nusinersen in Participants With Infantile-onset (Consistent With Type 1) Spinal Muscular Atrophy (SMA)

Infantile-onset Spinal Muscular Atrophy

New Zealand, Colombia, Turkey
Biogen

Recruiting

A Study to Evaluate Higher Dose (HD) Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy Previously Treated With Risdiplam (ASCEND)

Spinal Muscular Atrophy

United States, Germany, Italy, Hungary, Japan
Tongji Hospital

Recruiting

Effects of BRS and LRS on Postoperative Acute Kidney Injury (BRS/LRS)

Acute Kidney Injury

China
Beijing Tiantan Hospital

Not yet recruiting

Reducing Edema After intraCerebral Hemorrhage

Edema Brain
Biogen

Completed

An Open-label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy

Spinal Muscular Atrophy

United States
Biogen

Completed

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701)

Spinal Muscular Atrophy

United States
National Institute of Neurological Disorders and...

Completed

Nitrite Infusion in Healthy Volunteers

Healthy

United States
Livzon Pharmaceutical Group Inc.

Unknown

Shenqi Fuzheng Injection for the Treatment of Cancer-related Fatigue in Patients(BCS) With Digestive Tract .

Carcinogenic Fatigue

China
Biogen

Completed

An Open-label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246)

Spinal Muscular Atrophy

United States
The Second Hospital of Hebei Medical University

Unknown

Study on the Relationship Between Asymmetric Vascular Sign of Cortex and Prognosis in Massive Cerebral Infarction

Cerebral Infarction | Cerebral Edema

China
Biogen

Terminated

A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA). (EMBRACE)

Spinal Muscular Atrophy

United States, Germany
Southeast University, China

Unknown

Low-chlorine Vs High-chlorine Crystalloids in Septic Shock Adults

Septic Shock
Biogen

Completed

A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies (SHINE)

Spinal Muscular Atrophy

United States, Spain, Germany, United Kingdom, Australia, Japan, Canada, Belgium, France, Hong Kong, Italy, Korea, Republic of, Sweden, Turkey
Pfizer

Completed

A Phase 3 Study To Compare The Efficacy And Safety Of 0.3 MG Pegaptanib Sodium To Sham Injections In Subjects With Diabetic Macular Edema

Macular Edema | Retinal Disease | Diabetic Mellitus

Japan
Amckaus PTY LTD.

Recruiting

Aom0319 SAD Study in Healthy Subjects

Healthy Volunteers

Australia
Bausch & Lomb Incorporated

Completed

Extension Study to Gather Data on Effect of Macugen on the Corneal Endothelium

Age-Related Macular Degeneration | Diabetic Macular Edema | Retinal Vein Occlusion

United States
Biogen

Completed

An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA) (SMNRx)

Spinal Muscular Atrophy

United States
Biogen

Completed

A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy

United States, Canada
Green Valley Group of China

Unknown

Efficacy and Safety of Salvianolate Injection in Elderly Patients With Unstable Angina Pectoris

Unstable Angina

China
Afyonkarahisar Health Sciences University

Completed

The Efficacy of PRP Injection in the Treatment of Rotator Cuff Syndrome (PRP)

Musculoskeletal Diseases | Shoulder Pain | Rotator Cuff Tendinopathy | Rotator Cuff Syndrome

Turkey
Peking Union Medical College Hospital

Unknown

Using Sodium Lactate Ringer's Injection Resuscitate Septic Shock Patients

Lactate | Severe Sepsis With Septic Shock
CHU de Reims

Recruiting

Study of the Functional Effects of Nusinersen in 5q-spinal Muscular Amyotrophy Adults (SMA Type 2 or 3 Forms) (NUSI-AD-5qSM)

Spinal Muscular Atrophy

France
Eyetech Pharmaceuticals
Pfizer

Completed

Pegaptanib Sodium on Foveal Thickening in Patients With Exudative Subfoveal Age-Related Macular Degeneration (AMD)

Macular Degeneration
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Ultrasound-assisted vs Landmark Based Intrathecal Administration of Nusinersen

Muscular Atrophy, Spinal | Ultrasound

Italy
Göteborg University

Terminated

Saline Injections for Prophylactic Treatment of Chronic Migraine

Chronic Migraine

Sweden
Cellular Biomedicine Group Ltd.

Not yet recruiting

Allogenic Adipose-Derived Mesenchymal Progenitor Cells for the Treatment of Knee Osteoarthritis

Knee Osteoarthritis

China
Biogen

Terminated

A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (ENDEAR)

Spinal Muscular Atrophy

Korea, Republic of, United States, Spain, Canada, Germany, Australia, Japan, Sweden, Belgium, France, Italy, Turkey, United Kingdom
Caliway Biopharmaceuticals Co., Ltd.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of CBL-514 Compared to Placebo in Participants With Dercum's Disease Lipomas

Dercum's Disease
Bonti, Inc.

Completed

Study of EB-001 in Facial Scar Reduction

Mohs Surgery

United States
Henrik Wiggers

Recruiting

Physiological Effects of Lactate in Individuals With Chronic Heart Failure

Heart Failure, Systolic

Denmark
Biogen

Active, not recruiting

A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy (NURTURE)

Spinal Muscular Atrophy

United States, Taiwan, Israel, Australia, Qatar, United Kingdom, Turkey, Italy, Germany, Argentina, Canada
Shanghai Hutchison Pharmaceuticals Limited
Beijing Tiantan Hospital

Recruiting

Safety and Efficacy of SHPL-49 Injection in Participants With Acute Ischemic Stroke

Acute Ischemic Stroke

China
Hope Pharmaceuticals
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm

Subarachnoid Hemorrhage

United States
Prove pharm

Recruiting

Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency

Ureter Injury

United States
University of Oxford
Pfizer

Completed

Intravitreal Macugen for Ischaemic Diabetic Macular Oedema (MIDME)

Diabetic Macular Oedema

United Kingdom
Prove pharm

Recruiting

Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency in Patient's With Renal Impairment

Ureter Injury

United States
Spero Therapeutics
Clinical Network Services (CNS) Pty Ltd

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of SPR206 in Healthy Volunteers

Healthy Volunteers

Australia
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Ultrasound-assisted or Landmark-based Intrathecal Administration of Nusinersen in Adult Patients With Spinal Muscular Atrophy (The EchoSpin Study) (EchoSpin)

Ultrasonography | Spinal Muscular Atrophy | Anesthesia, Spinal | Spinal Puncture Complications

Italy

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