Search clinical trials for: OSI-906

Total 2675 results

Dompé Farmaceutici S.p.A
Cross Research S.A.

Completed

Single Dose, Two-stage Bioequivalence Study of SCMC-Lys Salt 1.35 g Powder vs SCMC-Lys Salt 90 mg/mL Syrup

Bronchitis

Switzerland
The Wistar Institute
National Institute of Allergy and Infectious Diseases (NIAID); Hoffmann-La... and other collaborators

Completed

Antiviral Activity of Peg-IFN-Alpha-2A in Chronic HIV-1 Infection

HIV Infections

United States
University of Liege

Completed

Nonmyeloablative Stem Cell Transplantation With CD8-depleted or Unmanipulated Peripheral Blood Stem Cells (PBSC)

Hematologic Malignancies

Belgium
Universidad Autonoma de Baja California

Completed

The Outcome of Preoperative Administration of Single-dose Ketorolac, Non-steroidal Anti-inflammatory Drug and Placebo (PreOp)

Pulpitis - Irreversible

Mexico
University of Campinas, Brazil

Completed

Acceptability and Continuation Rate of Implanon in a Brazilian Public Sector

Contraceptive Usage | Bleeding Due to Intrauterine Contraceptive Device

Brazil
National Cancer Institute (NCI)

Completed

Sorafenib With or Without Paclitaxel and Carboplatin in Treating Patients With Recurrent Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma

United States
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma

Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Neoplasm

United States
University Ghent

Completed

Pharmacokinetic Evaluation of Moxifloxacin Administered Intravenously and Orally in Healthy Volunteers Who Have Had a Gastric Bypass (DRUG10_MOXI)

Body Weight | Gastric Bypass

Belgium
HighField Biopharmaceuticals Corporation
Tigermed Consulting Co., Ltd

Recruiting

Tolerability and Safety of HF1K16 Injection in Patients With Refractory Solid Tumors

Solid Tumor, Adult

China
Sunnybrook Health Sciences Centre

Terminated

Anticoagulation Therapy Timing in Atrial Fibrillation After Acute and Chronic Subdural Hematoma (ATTAACH)

Atrial Fibrillation | Subdural Hematoma

Canada
Our Lady of the Lake Hospital
Louisiana State University Health Sciences Center - New Orleans

Active, not recruiting

Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid Injection

Meniere Disease | Intratympanic Steroid Injection | Idiopathic Sudden Sensorineural Hearing Loss

United States
Sheffield Teaching Hospitals NHS Foundation Trust
AstraZeneca

Completed

STEEL Percutaneous Coronary Intervention (STEEL-PCI)

Coronary Artery Disease

United Kingdom
University of Minnesota
Juvenile Diabetes Research Foundation

Terminated

Raptiva and Sirolimus in Islet Transplantation for Type 1 Diabetes (RAPTIVA)

Hypoglycemia | Type 1 Diabetes Mellitus

United States
National Cancer Institute (NCI)

Active, not recruiting

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

Malignant Solid Neoplasm | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Invasive Breast Carcinoma | Breast Adenocarcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With Advanced Cancer and Lymphoma

Lymphoma | Unresectable Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Canada
Sage Therapeutics

Completed

A Study to Evaluate Efficacy and Safety of SAGE-547 in Participants With Severe Postpartum Depression (547-PPD-202B)

Postpartum Depression

United States
Johns Hopkins University
Walter Reed Army Medical Center

Completed

Conservative Therapy Versus Epidural Steroids for Cervical Radiculopathy

Cervical Radiculopathy

United States
National Cancer Institute (NCI)

Active, not recruiting

Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Acute Myeloid Leukemia Post Cytotoxic Therapy

United States
Stanford University

Completed

A Phase 2 Trial of Rituximab and Corticosteroid Therapy for Newly Diagnosed Chronic Graft Versus Host Disease

Graft vs Host Disease

United States
Merz Pharmaceuticals GmbH

Completed

NT 201 (Xeomin®/Bocouture®) in Comparison With Clostridium Botulinum Toxin Type A in the Treatment of Glabellar Frown Lines (Head2Head)

Glabellar Frown Lines

United Kingdom, Germany, Austria
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Vemurafenib With Sorafenib Tosylate or Crizotinib in Treating Patients With Advanced Malignancies With BRAF Mutations

Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | BRAF Gene Mutation

United States
National Taiwan University Hospital
Merck Sharp & Dohme LLC

Completed

A Randomized, Double Blind, Placebo-controlled Study to Assess the the Preemptive Benefit of Etoricoxib in Patients Receiving Anterior Cruciate Ligament Reconstruction

Post-operational Pain

Taiwan
Osel, Inc.
National Cancer Institute (NCI); City of Hope Medical Center; Miyarisan Pharmaceuticals...

Recruiting

CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

Metastatic Renal Cell Carcinoma | Metastatic Clear Cell Renal Cell Carcinoma | Advanced Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Sarcomatoid Renal Cell Carcinoma | Advanced Renal Cell Carcinoma | Advanced Sarcomatoid Renal...

United States
National Cancer Institute (NCI)

Recruiting

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7

United States
National Cancer Institute (NCI)

Recruiting

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Mucosal Melanoma | Anal Melanoma | Bladder Melanoma | Cervical Melanoma | Esophageal Melanoma | Gallbladder Melanoma | Mucosal Melanoma of the Head and Neck | Mucosal Melanoma of the Urinary System | Oral Cavity Mucosal Melanoma | Penile Mucosal Melanoma | Rectal Melanoma | Recurrent Mucosal Melanoma | Sinonasal... and other conditions

United States, Canada
National Cancer Institute (NCI)

Recruiting

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV Infection | Anal Squamous Cell Carcinoma | Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | AIDS-Related Anal Carcinoma | Rectal Squamous Cell Carcinoma | Stage I Anal Cancer AJCC... and other conditions

United States
National Cancer Institute (NCI)

Suspended

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Locally Advanced Rectal Adenocarcinoma | Stage II Rectal Cancer AJCC v8

United States
National Cancer Institute (NCI)

Withdrawn

Testing Nivolumab and BMS-986016 (Relatlimab) as Potentially Targeting Treatment in Cancers That Are LAG-3+ and Have Mismatch Repair Deficiency (MATCH - Subprotocol Z1M)

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma
National Cancer Institute (NCI)

Active, not recruiting

Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors

Malignant Solid Neoplasm | Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Sarcomatoid Renal Cell Carcinoma | Stage III Bladder Cancer AJCC v8 | Stage III Renal Pelvis Cancer AJCC v8 | Stage III Ureter Cancer AJCC v8 | Stage... and other conditions

United States
University Hospital, Grenoble
EFCR Department and Sleep Laboratory, Grenoble Alpes University Hospital; Pneumology... and other collaborators

Recruiting

Integrated Management of Chronic Respiratory Diseases (eMEUSE-SANTE)

Sleep Apnea, Obstructive | Chronic Obstructive Pulmonary Disease

France
Zalicus

Terminated

CRx-102 Osteoarthritis Multicenter Evaluation Trial (COMET-1)

Knee Osteoarthritis

United States, Canada
Sahlgrenska University Hospital, Sweden

Not yet recruiting

Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic Cancer (PANCEP-1)

Pancreatic Cancer | Surgery | Metastasis | Immunosuppression
Kafrelsheikh University

Completed

Ticagrelor Versus Clopidogrel in Ischemic Stroke

Ischemic Stroke

Egypt
University of Magdeburg
Bayer; Sirtex Medical

Completed

Sorafenib and Micro-therapy Guided by Primovist Enhanced MRI in Patients With Inoperable Liver Cancer (SORAMIC)

Hepatocellular Carcinoma

Germany
Clinica Virgen Milagrosa
Merck Sharp & Dohme LLC

Terminated

Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder

Soft Tissue Injuries of the Shoulder | Tenosynovitis and Bursitis Affecting the Shoulder

Peru
University of Southampton
NIHR Clinical Research Facility, University Hospital Southampton NHS Foundation... and other collaborators

Terminated

High-Dose Melphalan With or Without Radiolabeled Monoclonal Antibody in Treating Patients With Multiple Myeloma Undergoing an Autologous Stem Cell Transplant (AntiCD-66)

Multiple Myeloma and Plasma Cell Neoplasm

United Kingdom
Hospices Civils de Lyon

Completed

EEG and Pharmacological Exploration of Executive Dysfunctions Induced by STN-DBS in PD (EEGDBSNAd)

Parkinson Disease

France
Georgetown University
Novartis

Withdrawn

Attenuating Ischemia Reperfusion Injury After Living Donor Renal Transplantation

Kidney Transplantation | Reperfusion Injury | Renal Transplantation
Cephalon

Terminated

Safety and Efficacy of SDX-101 (R-Etodolac) in Patients With Relapsed or Refractory Multiple Myeloma (MM)

Multiple Myeloma

United States
Garden State Cancer Center at the Center for Molecular...
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Recurrent Colorectal Cancer or Pancreatic Cancer

Colorectal Cancer | Pancreatic Cancer

United States
Mesoblast International Sàrl
National Cancer Institute (NCI)

Withdrawn

OTI-010 for Graft-Versus-Host Disease Prophylaxis in Treating Patients Who Are Undergoing Donor Peripheral Stem Cell Transplantation for Hematologic Malignancies

Myelodysplastic Syndromes | Leukemia | Graft Versus Host Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

90 Y-BC8-DOTA Monoclonal Antibody, Fludarabine Phosphate, and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma

Plasma Cell Myeloma | Refractory Plasma Cell Myeloma

United States
Peking University

Recruiting

The Effectiveness and Safety of FK-506 for the Treatment of Posner-Schlossman Syndrome

Posner Schlossman Syndrome

China
ImmunityBio, Inc.

Completed

Phase 3 Study to Treat Patients With Soft Tissue Sarcomas

Metastatic, Locally Advanced or Unresectable Soft Tissue Sarcoma

United States, Spain, Denmark, Israel, Canada, Australia, Hungary, Chile, France, Italy, Netherlands, Poland, Russian Federation
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI); National Center for Advancing...

Recruiting

Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension (MoD)

Pediatric Pulmonary Hypertension

United States, Canada
Meirav Kedmi MD
Johnson & Johnson

Unknown

Study of Ibrutinib in Combination With Bendamustine and Rituximab for Patients With Relapsed/Refractory Aggressive BCL

Diffuse Large B Cell Lymphoma | Recurrent Disease | Refractory Cancer | Primary Mediastinal (Thymic) Large B-cell Lymphoma | Transformed Indolent Lymphoma

Israel
Brynn Chappell
The Christie NHS Foundation Trust

Suspended

Individualisation of Voriconazole Antifungal Therapy Antifungal Therapy (PIVOTAL)

Aspergillosis | Immunocompromised Patient | Fusarium

United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Levonorgestrel and Ethinyl Estradiol for Oral Contraception

Contraception
DICE Therapeutics, Inc., a wholly owned subsidiary...

Completed

A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants

Healthy Participants

United States

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