Search clinical trials for: Org 24448

Total 6138 results

Merck Sharp & Dohme LLC

Completed

A Follow up Safety Study of Patients Who Participated in Previous Studies of the Drug Org 24448 (Study P05719)(COMPLETED)

Psychosis
Dennis Charney
National Institutes of Health (NIH)

Withdrawn

Randomized, Placebo-controlled Trial of an AMPAkine in Major Depressive Disorder

Major Depressive Disorder
National Institute of Mental Health (NIMH)

Terminated

Org 24448 to Treat Major Depression

Depression

United States
University of California, Los Angeles
Massachusetts General Hospital; Washington University School of Medicine; University... and other collaborators

Withdrawn

Org 24448 (Ampakine) for Cognitive Deficits in Schizophrenia

Schizophrenia

United States
National Taipei University of Nursing and Health...

Recruiting

The Effect of Digital Reminiscence Therapy on People With Mild and Moderate Dementia

Dementia

Taiwan
GlaxoSmithKline

Completed

Determination of the Sun Protection Factor (SPF) of a Cosmetic Daily De-fence Skin Cream

Sunscreening Agents

Germany
Weill Medical College of Cornell University

Completed

Safety Study of ORG 34517 for Major Depression With Psychotic Features

Psychotic Disorders | Major Depressive Disorder

United States
Abbott Medical Devices

Not yet recruiting

External Sensing and Neuromodulation to Assess Diabetic Pain Outcomes (XANADO) (XANADO)

Chronic Pain

United States
Origo Biopharma

Completed

First in Human Study of ORG-129 in Healthy Volunteers

Healthy Volunteers

Spain
Merck Sharp & Dohme LLC

Completed

A Study to Determine the Efficacy and Safety of 2 Doses of Org 34517 as Adjunctive Therapy in Subjects With Psychotic Major Depression (28130)(P05845) (Hermes)

Depression | Psychotic Disorders | Depressive Disorders
GlaxoSmithKline

Completed

Sun Protection Factor (SPF) Determination of Two Sunscreen-Containing Lip Balms

Sunscreening Agents

United States
Guangzhou General Hospital of Guangzhou Military...
Guangdong Provincial Hospital of Traditional Chinese Medicine

Recruiting

Pharmacokinetics of Sugammadex for the Reversal of Moderate Neuromuscular Blockade in Patients During Renal Transplantation

Pharmacokinetics

China
Merck Sharp & Dohme LLC

Completed

Safety of Org 34517 900 mg in Patients Who Received Org 34517 in a Previous Trial (Study 28133/P05842)

Depression | Psychotic Disorders | Depressive Disorders
Janssen Research & Development, LLC

Active, not recruiting

A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (MARIPOSA)

Carcinoma, Non-Small-Cell Lung

United States, France, Canada, China, Israel, Belgium, United Kingdom, Italy, Argentina, Japan, Taiwan, Thailand, Korea, Republic of, Malaysia, Poland, Australia, Spain, Netherlands, Hungary, Turkey, Germany, India, Brazil, Russian Federation and more
Merck Sharp & Dohme LLC

Terminated

Org 25935 Versus Placebo as Augmentation to Cognitive-behavioral Therapy to Treat Panic Disorder (P05705)

Panic Disorder
Merck Sharp & Dohme LLC

Completed

Efficacy, Pharmacokinetics and Safety of Org 25969 in Subjects With Normal or Impaired Renal Function (19.4.304)(P05948)(COMPLETED)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

Comparison of 4.0 mg/kg Sugammadex at 1-2 Post Tetanic Counts (PTC) in Renal or Control Patients (19.4.328)(P05769)

Anesthesia
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy Evaluation of Sugammadex in Cardiac Patients (19.4.309)(P05934)

Anesthesia
Guangzhou General Hospital of Guangzhou Military...

Recruiting

Pharmacokinetics of Sugammadex in Reversal of Vecuronium-induced Neuromuscular Blockade in Patients During Laparoscopic Surgery

Pharmacokinetics

China
Organon and Co

Completed

Study to Investigate the Optimal Dose of Org 36286 to Induce Monofollicular Ovulation in Women With WHO Group II Anovulatory Infertility (P07016)

Infertility
Merck Sharp & Dohme LLC

Completed

Comparison of the Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616; Org 25969) in Elderly Participants With Adult Participants (MK-8616-029)

Anesthesia, General
Organon and Co

Completed

A Trial of Single Dose Corifollitropin Alfa's Ability to Induce Multiple Follicular Growth During the First Week of Controlled Ovarian Stimulation for IVF or ICSI (38833)(P05788) (Realize)

In Vitro Fertilization
Merck Sharp & Dohme LLC

Completed

Adjuvant Treatment With a Glycine Uptake Inhibitor in Participants With Negative Symptoms of Schizophrenia (P05695) (MK-8435-001) (GIANT)

Schizophrenia
University of Plymouth
Veeda Clinical Research; Organon Teknika

Completed

First Administration to Man Of Org 25435 a New Intravenous Anesthetic

Anaesthesia

United Kingdom
Janssen Research & Development, LLC

Active, not recruiting

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure (MARIPOSA-2)

Carcinoma, Non-Small-Cell Lung

Canada, Germany, Italy, China, Belgium, United States, Taiwan, Israel, United Kingdom, Korea, Republic of, Sweden, Japan, Poland, Malaysia, Netherlands, Spain, Turkey, France, India, Mexico, Argentina, Brazil, Portugal, Russian Federation and more
Universidad El Bosque, Bogotá
Gloria Lafaurie; Carlos Leal

Completed

Horizontal Ridge Augmentation in Mandible Usign ROG + ESWT

Bone Regeneration

Colombia
Guangzhou General Hospital of Guangzhou Military...

Recruiting

Effect of Sugammadex for Reversal of Rocuronium-induced Neuromuscular Block on Perioperative Management of Awake Craniotomy

Brain Tumors

China
Washington University School of Medicine
The Craig H. Neilsen Foundation

Completed

Motor Learning Approach for Manual Wheelchair Users

Spinal Cord Injuries

United States
Merck Sharp & Dohme LLC

Completed

Use of Sugammadex Administered at 5 Minutes After Administration of 1.2 mg/kg Esmeron® (19.4.205)(P05942)

Anesthesia, General
Guangzhou General Hospital of Guangzhou Military...

Unknown

Pharmacokinetics and Pharmacodynamics of Sugammadex in Reversal of Vecuronium-induced Neuromuscular Blockade

Pharmacokinetics | Pharmacodynamics

China
Merck Sharp & Dohme LLC

Completed

A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part A: Japanese Participants (P05956)

Anesthesia, General
Organon and Co
CRS Mannheim GmbH

Completed

A Trial to Assess the Pharmacokinetic Profile (e.g., Uptake, Distribution and Excretion of a Substance in the Body) of Nomegestrol Acetate (NOMAC), Estradiol (E2) and Estrone (E1) After Multiple and Single Dose Administration of the Combined Oral Contraception NOMAC-E2 (COMPLETED)(P05822)

Healthy
Orion Corporation, Orion Pharma

Completed

Early Phase I Microdosing Study of ORM-14540 and ORM-12741

Healthy

Finland
Merck Sharp & Dohme LLC

Completed

Relation Between TOF-Watch® SX and a Peripheral Nerve Stimulator After 4.0 mg.Kg-1 Sugammadex (P05698)

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of 4.0 mg/kg Sugammadex at 1-2 PTC in Chinese and European Subjects (Study 19.4.335)(P05775AM1)(COMPLETED)

Anesthesia, General | Neuromuscular Blockade
Organon and Co

Completed

To Investigate Efficacy and Safety of a Single Injection of Org 36286 for Ovarian Stimulation Using Daily Recombinant FSH as Reference (Ensure)(P05690/MK-8962-001) (Ensure)

Infertility
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of Single Doses of ORM-12741 (Nebula PK 1)

Healthy

Finland
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of Multiple Doses of ORM-12741 (Nebula PK 2)

Healthy

Finland
Orion Corporation, Orion Pharma

Completed

Safety and Pharmacokinetic Study With Multiple Ascending Doses of ORM-12741

Healthy

France
Orion Corporation, Orion Pharma

Completed

Safety and Efficacy of ORM-12741 in Patients With Alzheimer's Disease (ALPO)

Alzheimer's Disease

Finland
Orion Corporation, Orion Pharma

Terminated

Efficacy of ORM-12741 for Prevention of Raynaud's Phenomenon (REINO)

Raynaud's Phenomenon

United Kingdom
Maculaser Oy

Completed

Fundus Image-guided Focal Electroretinography, Usability Study

Healthy | Macular Degeneration | Macular Edema

Finland
Merck Sharp & Dohme LLC

Completed

A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Japanese Participants. Part A (P05957)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Caucasian Participants. Part B (P05974)

Anesthesia, General
Mayo Clinic

Completed

Comparison of Different Oral Rehydration Solutions (ORS)

Short Bowel Syndrome

United States
University of Aarhus
Aarhus University Hospital Skejby; Department of Microbiological Surveillance...

Completed

A Pharmacokinetic and Pharmacodynamic Study of Phenoxymethylpenicillin for Children

Phenoxymethylpenicillin

Denmark
University Hospital Tuebingen

Unknown

Influence of Hypoxia on Electroretingraphy (ERG) Measurements

ERG Under Hypoxia

Germany
MedRegen LLC
Vanderbilt University Medical Center

Not yet recruiting

MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients (SUMMIT)

Respiratory Tract Diseases | Respiratory Failure | Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome | Cytokine Storm
Oryzon Genomics S.A.
Alzheimer's Drug Discovery Foundation

Completed

Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease (ETHERAL-US)

Mild to Moderate Alzheimer's Disease

United States
Organon and Co

Completed

To Determine Long Term Efficacy and Safety of Asenapine in Schizophrenic Patient Population (A7501012)(COMPLETED)(P05770)

Schizophrenia

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