Search clinical trials for: PA-824

Total 1437 results

Global Alliance for TB Drug Development

Completed

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009) (CL-009)

Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Pretomanid in Adults With Hepatic Impairment

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

A Study of the Safety, Tolerability, and Absorption, Metabolism, and Excretion of PA-824 in Healthy Adult Male Subjects. (CL-004)

Tuberculosis

United States
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Single-Dose Study to Evaluate the PKs of Pretomanid in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function

Renal Impairment | Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

A Study in Two Panels of Healthy Adult Participants to Assess Single-Dose Immediate-Release and Single-Dose Dispersible Formulations of Pretomanid

Multi-drug Resistant Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-003)

Tuberculosis

United States
Global Alliance for TB Drug Development

Completed

PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (CL-010)

Pulmonary Tuberculosis
Bayer

Completed

Safety and Efficacy of BAY94-9027 in Previously Treated Male Children With Haemophilia A

Hemophilia A

Belgium, New Zealand, Netherlands, Greece, United Kingdom, Austria, United States, Italy, Romania, Bulgaria, Canada, Israel, Poland, Lithuania, Norway, Argentina, Spain
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) (NC-003)

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

A Phase 3 Study Assessing the Safety and Efficacy of Bedaquiline Plus PA-824 Plus Linezolid in Subjects With Drug Resistant Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Mackay Memorial Hospital
OBI Pharma, Inc

Unknown

Trial of Active Immunotherapy With Globo H-KLH (OPT-822/821) in Women Who Have Non-Progressive Ovarian Cancer

Ovarian Cancer

Taiwan
Global Alliance for TB Drug Development

Completed

Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis (ZeNix)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis | Tuberculosis, MDR | XDR-TB | Pre-XDR-TB

South Africa, Russian Federation, Georgia, Moldova, Republic of
Rush University Medical Center
University of Illinois at Chicago; Michigan State University

Active, not recruiting

Testing Adaptive Interventions to Improve Physical Activity for Sedentary Women

Physical Activity

United States
St. Justine's Hospital

Recruiting

Dynamo: a Tailored Lifestyle Promotion Intervention Among Pediatric Patients With Cardiometabolic Risk Factors (CIRCUIT)

Obese

Canada
Global Alliance for TB Drug Development

Completed

Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002)

Pulmonary Tuberculosis

Tanzania, South Africa
Professor Jiska Cohen-Mansfield

Completed

Physical Activity With Social Support Adherence Intervention (PASAI)

Sedentary Status of Older Adults
University of Pittsburgh

Completed

Comparison of Supervised and Unsupervised Physical Activity Programs During a Weight Loss Intervention for Adults (REACH)

Obesity

United States
Centers for Disease Control and Prevention
Pennsylvania Department of Health; American Academy of Pediatrics

Completed

Pennsylvania Abusive Head Trauma Prevention Program

Child Abuse | Traumatic Brain Injury | Injury
Hospices Civils de Lyon
Institut National de la Santé Et de la Recherche Médicale, France; Centre National... and other collaborators

Recruiting

Prismatic Adaptation for Rehabilitation of Postural Imbalance After Stroke (PEQUIE)

Chronic Right Supratensorial Stroke Patients

France
Istituti Clinici Scientifici Maugeri SpA
University of Bologna

Completed

Temporal Disorders in Left and Right Brain-Damaged Patients

Brain Disease

Italy
Ben-Gurion University of the Negev

Completed

Diet and Body Composition (CENTRAL)

Obesity

Israel
The Miriam Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Exercise Values of Life and Vitality Everyday (EVOLVE)

Physical Activity | Exercise | Behavior | Lifestyle | Acceptance and Commitment Therapy | ACT | Lifestyle, Sedentary

United States
University of Texas at Austin

Terminated

Evaluation of AVANCE Fathers in Action/Padres Activos Fatherhood Program (AVANCE)

Fathers
Federico II University

Completed

Combined Nutritional and Exercise Strategies to Reduce Liver Fat Content in Patients With Type 2 Diabetes

Type 2 Diabetes | Postprandial Lipids Metabolism
University of Michigan

Completed

Social Media Intervention - Physical Activity

Cannabis Use

United States
Duke University

Completed

Engaging African American Older Adults With Arthritis in a Physical Activity Intervention

Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Ottawa Heart Institute Research Corporation

Withdrawn

Surgical PA-LAA Shunting: a Feasibility Study (PA-LAA)

LAA Thrombus Prevention

Canada
Duzce University
Cukurova University

Completed

Needle Knife Fistulotomy Versus Partial Ampullary Endoscopic Mucosal Resection for Difficult Biliary Cannulation

Common Bile Duct Calculi | Biliary Disease | Biliary Stricture | Malignant Hepatobiliary Neoplasm | Pancreatic Disease

Turkey
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study to Evaluate Efficacy of Different Natural Ingredients in Improving Gut Health in Adults With Leaky Gut.

Gut Health

India
Unity Health Toronto
University of Toronto

Not yet recruiting

Physical Activity Program for TRD

Major Depressive Disorder | Treatment-resistant Depression

Canada
Poitiers University Hospital
Hospices Civils de Lyon; Centre Hospitalier Universitaire Dijon; University Hospital... and other collaborators

Recruiting

Efficacy of a High-intensity Physical Activity Program on Renal Function in High Risk Patients With Type 2 Diabetes (ACTIDIANE)

Diabetic Kidney Disease | Type2 Diabetes

France, Belgium
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

A Multicenter Research on the Effects of Substitution of Hospital Ward Care From Medical Doctors to Physician Assistants

Substitution of Care

Netherlands
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study to Evaluate the Efficacy of EB-PA on Muscle Mass and Strength in Occasional Gym Goers

Muscle Mass and Strength

India
University of Jaen

Completed

Value of Manual Therapy Specificity Referred to Pain Intensity in Patients With Subacute and Unspecified Low Back Pain

Low Back Pain

Spain
National Institute of Allergy and Infectious Diseases...

Completed

Effect of PA-824 and of PA-824 Plus Moxifloxacin on the QTc Interval in Healthy Volunteers

Tuberculosis

United States
Western University, Canada
East Elgin Family Health Team

Recruiting

Family Health Team High-Intensity Interval Training (FHT HIIT)

Type 2 Diabetes

Canada
KU Leuven

Recruiting

Enhancing Muscle Function After Exacerbations of COPD to Limit Its Impact on Physical Activity Decline

COPD Exacerbation

Belgium
Stryker Orthopaedics

Completed

Evaluation of Triathlon - A New Total Knee Prosthesis System - Triathlon PA vs. Triathlon Pressfit (TriathlonRSA)

Arthroplasty, Replacement, Knee

Sweden
Hong Kong Baptist University

Completed

Effects of a PA Intervention for Fatness and Fitness in Adolescents With Intellectual Disability

Obesity | Intellectual Disability | Health-related Physical Fitness

China
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Completed

Effectiveness of DECIDE in Patient-Provider Communication, Therapeutic Alliance & Care Continuation (PCORI)

Mental Disorders

United States
Johns Hopkins University
National Institute of Mental Health (NIMH)

Completed

Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses

Personality Disorders | Depression | Schizophrenia | Anxiety Disorders | Bipolar Disorder | Cognitive Disorders

United States
University of Seville

Recruiting

Effect of a HIIT Program on Quality of Life, Executive Functions, and IGF-1 Response in Sedentary Young University Women

Insulin Growth Factor I Deficiency | IGF1 Deficiency | Executive Function Disorder

Spain
Rambam Health Care Campus
CogMe Ltd

Recruiting

CogMe for the Prevention and Early Detection of Delirium (CogMe)

Delirium

Israel
University of California, San Francisco
Patient-Centered Outcomes Research Institute; San Francisco Hep B Free Campaign

Completed

Patient-Centered Care and Asian Americans

Hepatitis B | Hepatitis C | Liver Disease

United States
Samyang Biopharmaceuticals Corporation

Completed

A Pilot Study to Investigate the Efficacy of Partially Absorbable Mesh in Patients With Pelvic Organ Prolapsed

Pelvic Organ Prolapse

Korea, Republic of
University of Sao Paulo

Unknown

Cardiovascular Risk in Sedentary Elderly During Prolonged Sitting Time Versus Intermittent Sitting Time

Sedentary Lifestyle

Brazil
Stanford University
National Institute on Aging (NIA)

Recruiting

Testing Multi-Level Remote Physical Activity Interventions in a National Sample of Older Women: The WHISH EnCore Trial (WHISH EnCore)

Physical Inactivity

United States
Butler Hospital

Recruiting

Optimization of a Behavioral Intervention to Increase Physical Activity in Older Adults Living With HIV (HiActivity)

Aging | Hiv | Physical Inactivity

United States
Aalborg University Hospital
Aalborg University

Not yet recruiting

Wearable Sensors for Monitoring Recovery After Total Knee Arthroplasty

Arthroplasty, Replacement, Knee

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