Search clinical trials for: PCSK9 inhibitor plus statin

Total 1650 results

Nanjing First Hospital, Nanjing Medical University
National Natural Science Foundation of China; Nanjing Medical University

Recruiting

PCSK 9 Inhibitor Added to High-Intensity Statin Therapy to Prevent Cardiovascular Events in Patients With ACS After PCI (SHAWN)

Hyperlipidemias | Acute Coronary Syndrome | Percutaneous Coronary Intervention | Cardiovascular Events

China
University of Campania "Luigi Vanvitelli"

Completed

Molecular Mechanisms and Carotid Atherosclerosis

Diabetes Mellitus, Type 2 | Atherosclerotic Plaque | Atherosclerosis of Artery

Italy
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Low-dose PCSK9 Inhibitor Combined With Stains on Serum Lipids in Chinese Population With Acute Coronary Syndrome

Acute Coronary Syndrome

China
Beijing Anzhen Hospital

Completed

Impact of PCSK9 Inhibitors on Coronary Plaque Composition and Vulnerability Assessed by Optical Coherence Tomography

Randomized Controlled Trials

China
Xuanwu Hospital, Beijing

Not yet recruiting

Short-term Effect of PCSK9 Inhibitor in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke
Lin Zhao

Recruiting

Effect of Evolocumab on Chronic Total Occlusions (EVOLO-CTO)

In-stent Restenosis | Major Adverse Cardiovascular Events

China
NYU Langone Health

Completed

CHOlesterol Lowering and Residual Risk in Type 2 Diabetes (CHORD)

Type 2 Diabetes

United States
Shenzhen People's Hospital

Recruiting

Acute Myocardial Infarction and Unstable Angina Patients With PCSK9 Inhibitor Usage Study

Cardiovascular Diseases | Lipid Metabolism

China
Shanghai Tong Ren Hospital

Recruiting

Impact of Early PCSK9 Inhibitor on Heart After Acute Myocardium Infarction (PERFECT-AMI)

Early PCSK9 Inhibitor on Ventricular Remodling

China
Seoul National University Hospital

Unknown

PCSK9 Inhibitors in the Progression of Aortic Stenosis

Aortic Valve Stenosis

Korea, Republic of
Beijing Anzhen Hospital
Beijing Municipal Health Commission

Not yet recruiting

Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis: A Randomized Trial (EPISODE)

Aortic Stenosis

China
Icahn School of Medicine at Mount Sinai

Completed

Rosuvastatin and Evolocumab for Coronary Artery Disease (Yellow V)

Coronary Artery Disease

United States
South Valley University

Not yet recruiting

US vs. LASER on Post Cesarean Anterior Cutaneous Branches of Iliohypogastric Neurotmesis

Neurotmesis

Egypt
CHU de Quebec-Universite Laval
Canadian Institutes of Health Research (CIHR); Biovalorem

Recruiting

Cholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic Adenocarcinoma

Pancreatic Cancer | Metastatic Cancer | Pancreatic Ductal Adenocarcinoma | Pancreas Cancer

Canada
Beijing Friendship Hospital
Changhai Hospital; Peking Union Medical College Hospital; Peking University Cancer...

Not yet recruiting

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

China
Pauls Stradins Clinical University Hospital

Active, not recruiting

Impact of Optimal Pharmacotherapy on Lipid Profile and Qualitative Features of Atherosclerotic Plaques

Atherosclerotic Cardiovascular Disease

Latvia
University of Kansas Medical Center
University of Missouri-Columbia; American Heart Association

Completed

Exercise, Statins, and the Metabolic Syndrome

Metabolic Syndrome | Obese | Sedentary

United States
Wuhan Union Hospital, China

Recruiting

High-Resolution Assessment of Extracranial Plaques in a Multiple Centers Evolocumab Randomized Study

Cerebral Atherosclerosis

China
RenJi Hospital

Recruiting

Exploratory Research of PCSK9 Inhibitor on Patency of aAVF After PTA With PCB

Hemodialysis Access Failure

China
Jose Seijas Amigo

Completed

Study to Evaluate Changes in Cognitive Function in Patients Treated With PCSK9 Inhibitors (MEMOGAL)

Quality of Life | Hypercholesterolemia | Cognitive Function

Spain
Nanjing First Hospital, Nanjing Medical University

Recruiting

Improving Blood Lipid Management in Symptomatic Intracranial Atherosclerotic Stenosis on Clinical Outcome (sICASBLM)

Intracranial Artery Stenosis

China
Seung-Whan Lee, M.D., Ph.D.
Yuhan Corporation

Recruiting

Comparison of Low-Intensity Statin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus (PROVE-DM)

Pre Diabetes | ASCVD

Korea, Republic of
Xiang Xie
Xinjiang Medical University

Not yet recruiting

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Cancer | Atherosclerotic Cardiovascular Disease | ASCVD | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor
Samsung Medical Center

Not yet recruiting

High-intensity Statin and Ezetimibe Therapy for Asymptomatic Patients With Positive Coronary Calcium (DECISION-CAL)

Metabolic Syndrome | Dyslipidemias | Coronary Artery Calcification
National Medical Research Center for Therapy and...

Recruiting

Efficacy and Safety of Pitavastatin and PCSK9 Inhibitors in Liver Transplant Patients (PINTL)

Dyslipidemias | Hyperlipidemias | Liver Transplant Disorder | Immunosuppression | Hydroxymethylglutaryl-CoA Reductase Inhibitors | Statins

Russian Federation
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
University of Ioannina

Unknown

Comparison of High-Dose Rosuvastatin Versus Low Statin Dose Plus Fenofibrate Versus Low Statin Dose Plus Niacin in the Treatment of Mixed Hyperlipidemia

Dyslipidemia

Greece
Yonsei University

Recruiting

Effect of High-intensity Statin With Ezetimibe COmbination theRapy Versus High-intensity sTatin Monotherapy After Percutaneous Coronary Intervention With Drug-eluting Stents; the ESCORT Trial

Coronary Artery Disease Requiring Coronary Revascularization With Newer Generation DES Implantation

Korea, Republic of
GWT-TUD GmbH

Active, not recruiting

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry (PERI-DYS)

Dyslipoproteinemias

Germany
Zibo Central Hospital

Recruiting

Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy

Adverse Effect of Cardiovascular Medications (Diagnosis)

China
Brigham and Women's Hospital
Amgen

Recruiting

Lipid Management in Renal Transplant Recipients Using Evolocumab.

Hyperlipidemias

United States
The Medicines Company

Completed

Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C) (ORION-1)

Diabetes | Familial Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

Canada, Netherlands, United States, United Kingdom, Germany
Guangdong Provincial People's Hospital

Not yet recruiting

PCSK9 Inhibitors in Combination With Advanced Treatment Strategies for the Treatment of Advanced Colorectal Cancer With pMMR/MSS

Colorectal Cancer
The Medicines Company

Completed

A Study of ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (ORION-2)

Homozygous Familial Hypercholesterolemia

United States, Netherlands, South Africa
Pfizer

Completed

A Multiple Dose Study of PF-04950615 (RN316) in Subjects on High Doses of Statins

Dyslipidemia | Hypercholesterolemia

United States, Canada
Universidad Autonoma de San Luis Potosí

Completed

Assessment of the Effects of Synbiotic on Gut Microbiota Composition in Scholars With Overweight

Childhood Obesity | Childhood Overweight

Mexico
Tirat Carmel Mental Health Center
Ariel University

Completed

Spectrophon LTD Glucometry Monitor Accuracy

Glucose Metabolism Disorders | Diabetes Mellitus

Israel
China National Center for Cardiovascular Diseases
Innovent Biologics, Inc.

Not yet recruiting

Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese Population

Acute Coronary Syndrome | Non ST Segment Elevation Acute Coronary Syndrome
Organon and Co

Completed

Retrospective Survey Evaluating the Effectiveness and Safety of Dual Inhibition Lipid-lowering in the Treatment of Dyslipidemia (Study P05171)(COMPLETED)

Dyslipidemia
Korea University Anam Hospital

Not yet recruiting

To Assess With Ezefeno Tab. in Patients With Dyslipidemia and T2DM (ENSEMBLE)

Dyslipidemias | T2DM (Type 2 Diabetes Mellitus)

Korea, Republic of
The Alfred

Completed

Polypharmacy in the Heart Failure Patient: Are All Prescribed Drug Classes Required? Statin Withdrawal Study

Heart Failure

Australia
James Backes, PharmD
Marcor Development Corporation

Completed

Effect of Policosanol as Monotherapy and Adjunctive to Statin Therapy

High Cholesterol

United States
Jena University Hospital

Not yet recruiting

Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target) (GoT)

ST Elevation Myocardial Infarction | Non-ST Elevation Myocardial Infarction | LDL-cholesterol

Germany
Tongji Hospital

Recruiting

Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis

Ischemic Stroke | Large-Artery Atherosclerosis (Embolus/Thrombosis)

China
Yonsei University

Unknown

Aspirin Mono Therapy 12-months After Drug-eluting Stents Implantation (statin)

Drug-eluting Stent (DES)

Korea, Republic of
Yonsei University

Not yet recruiting

Low- and Moderate-intensity Statin and Clinical Outcome of Primary Prevention in Individuals Aged >75 Years: the SCOPE-75 RCT Study

Healthy Elderly Individuals With High LDL-cholesterol or Risk of Cardiovascular Disease

Korea, Republic of
Shiraz University of Medical Sciences

Completed

Effective Dose of Statin Post PCI

Statin Dose

Iran, Islamic Republic of
University of Roma La Sapienza

Unknown

Low Dose Statins, Ezetimibe and Nutraceuticals (TACO)

Coronary Artery Disease

Italy
OptiScan Biomedical Corporation

Unknown

MANAGE Automated Glucose Monitoring (MANAGE IDE)

ICU/CCU Patients Requiring Blood Glucose Monitoring

United States
Federal University of São Paulo

Completed

Effect of Simvastatin and Ezetimibe on Lipid and Inflammation

Inflammation | Hypercholesterolemia | Cardiovascular Risk | Prediabetes

Brazil

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