Search clinical trials for: PDE5 inhibitor

Total 64651 results

Saint Petersburg State University, Russia

Recruiting

Efficacy and Safety of Focused Shockwave Therapy Plus Tadalafil vs Tadalafil Alone in Patient With Erectile Dysfunction

Erectile Dysfunction

Russian Federation
Assiut University

Unknown

Assessment of Early Outcomes of Roflumilast in Patients With Non Cystic Fibrosis Bronchiectasis

Bronchiectasis
Herlev Hospital

Withdrawn

Effect of Tadalafil in Chronic Obstructive Lung Disease Patients Suffering From Secondary Pulmonary Hypertension

Chronic Obstructive Lung Disease

Denmark
Brigham and Women's Hospital
Johns Hopkins University; National Institute on Aging (NIA); Rutgers University

Completed

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - PDE5 Inhibitors vs Endothelin Receptor Antagonist

Pulmonary Arterial Hypertension

United States
Samsun Liv Hospital
Ondokuz Mayıs University

Completed

Effects of Tadalafil on LMR and MHR in Patients With ED

Inflammation | Erectile Dysfunction

Turkey
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell Disease

Sickle Cell Disease | Pulmonary Hypertension

United States, United Kingdom
Maastricht University Medical Center

Recruiting

Cognitive Effects of Roflumilast in (a)MCI and Mild Dementia Patients (ROMEMA)

Mild Cognitive Impairment | Mild Dementia | Amnestic Mild Cognitive Disorder

Netherlands
Maastricht University
Netherlands Brain Foundation

Completed

Roflumilast to Treat Cognitive Sequela After Stroke (ROSTMEMA)

Cerebrovascular Disorders | Functional Recovery | Memory | Drug Intervention

Netherlands
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Concomitant Use of PriLigy in Men Treated for Erectile Dysfunction (COUPLE)

Sexual Dysfunction | Erectile Dysfunction

France, Poland, United States, Belgium, Mexico, Malaysia, Canada, Taiwan, Korea, Republic of, Russian Federation, Argentina, Australia, United Kingdom
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Roflumilast and Cognition (EEGrofl)

Dementia

Netherlands
Beth Israel Deaconess Medical Center

Completed

Coenzyme Q10 in Post-Cardiac Arrest Cerebral Resuscitation

Cardiac Arrest | Sudden Cardiac Arrest

United States
Regina Elena Cancer Institute

Recruiting

Low Intensity Shock Wave Therapy in the Rehabilitation Treatment of Erectile Dysfunction After Robotic Radical Prostatectomy.

Erectile Dysfunction

Italy
Eli Lilly and Company

Completed

A Study to Determine if There is a Possible Association Between NAION and Phosphodiesterase Type 5 (PDE5) Inhibitors

Nonarteritic Anterior Ischemic Optic Neuropathy

United States
Ospedale San Raffaele

Unknown

Fundus Oculi and Erectile Dysfunction

Erectile Dysfunction

Italy
Ganzhou Hemay Pharmaceutical Co., Ltd

Recruiting

A Study of Efficacy and Safety of Hemay005 Tablets in Patients With Behçet's Disease

Behçet's Disease

China
Tianjin Hemay Pharmaceutical Co., Ltd

Terminated

A Study to Evaluate the Efficacy and Safety of Hemay005 in the Treatment of Behçet Disease

Behçet Disease

China
Vitaflo International, Ltd
Radboud University Medical Center; Great Ormond Street Hospital for Children...

Completed

Evaluation of PDE MAX (PDE MAX)

Pyridoxine Dependant Epilepsy

Netherlands, United Kingdom
University Hospital, Brest

Completed

Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome (DIStress-AG)

General Anaesthesia | Severe Trauma

France
NMP Medical Research Institute

Completed

Homeopathy as an Adjuvant to Chemotherapy Improves Clinical Outcome in Relapsed Pulmonary Tuberculosis

Pulmonary Tuberculosis

India
International Islamic University, Islamabad

Completed

Psychotherapy and Pharmacotherapy in the Treatment of Erectile Dysfunction: A Pilot Study

Erectile Dysfunction

Pakistan
Mansoura University

Unknown

Role of Low-intensity Shock Wave Therapy in Penile Rehabilitation Post Nerve Sparing Radical Cysto-prostatectomy

Bladder Cancer

Egypt
Mansoura University

Active, not recruiting

A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.

Erectile Dysfunction Following Radiation Therapy | Phosphodiesterase Inhibitor Adverse Reaction | Platelet- Rich Plasma (PRP)

Egypt
Ottawa Heart Institute Research Corporation

Completed

Milrinone Versus Dobutamine in Critically Ill Patients

Acute Coronary Syndrome | Pulmonary Edema | Cardiogenic Shock | Low Cardiac Output Syndrome

Canada
United Therapeutics

Completed

Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies (Aspire)

Pulmonary Arterial Hypertension

United States
Stanford University

Not yet recruiting

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

Brain Tumor

United States
Amsterdam UMC, location VUmc

Unknown

Goal Oriented Strategy to Preserve Ejection Fraction Trial (GOSPEL)

Pulmonary Arterial Hypertension

Netherlands
Mayo Clinic
National Institutes of Health (NIH)

Completed

Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal Dysfunction (Aim 3 BNP/PDEV)

Heart Failure | Renal Dysfunction
Barretos Cancer Hospital

Unknown

Fluorescence Surgery for Sentinel Node Identification in Melanoma

Melanoma | Lymph Node Metastasis

Brazil
Centre Hospitalier Universitaire de Nīmes

Completed

Low Energy Shockwave Therapy for Improving Erectile Dysfunction (Shock-ED)

Erectile Dysfunction

France
Duke University
Pediatric Pharmacology Research Units Network

Completed

Antimicrobial PK in Infants With Suspected or Confirmed Infection

Infection

United States
NYU Langone Health

Completed

Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients

Scoliosis | Surgery | Intracranial Aneurysm | Brain Edema

United States
Case Comprehensive Cancer Center

Recruiting

Evaluation of an Integrated Imaging System For In Vivo Detection of Fluorescently Labeled Lesions

Invasive Breast Cancer

United States
CTI BioPharma

Terminated

PRE-VENT Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer

COVID-19 | COVID | COVID19

United States
Samsung Medical Center

Recruiting

Peri-treatment of SGLT-2 Inhibitor on Myocardial Infarct Size and Remodeling Index in Patients With Acute Myocardial Infarction and High Risk of Heart Failure Undergoing Percutaneous Coronary Intervention (PRESTIGE-AMI)

Heart Failure | Acute Myocardial Infarction

Korea, Republic of
Pfizer

Completed

European Treatment Patterns and Outcomes Associated With First-Line CDK4/6 Inhibition and Hormonal Therapies (EUCHARIS)

Metastatic Breast Cancer

Spain, Belgium, Sweden, United Kingdom, Austria, Germany, Switzerland
Tianjin Medical University Cancer Institute and...

Recruiting

PD1 and PARP for Maintenance Therapy in NSLLC

Lung Cancer

China
Peking University
Hangzhou DIAN Medical Diagnostic Center Co., Ltd., China

Recruiting

Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics (VISIONARY)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Esophageal Squamous Cell Carcinoma | Biliary Tract Neoplasms | Unknown Primary Cancer | Digestive Cancer

China
Beijing Friendship Hospital
Changhai Hospital; Peking Union Medical College Hospital; Peking University Cancer...

Not yet recruiting

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

China
Vanderbilt University Medical Center

Completed

Angiotensin Converting Enzyme Inhibitors During Cardiopulmonary Bypass in Infants and Children

Congenital Heart Disease

United States
UNC Lineberger Comprehensive Cancer Center
GlaxoSmithKline

Completed

LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations

Unresectable Melanoma | Stage IV Melanoma | Stage III Melanoma | BRAF Mutant Melanoma

United States
Omega Therapeutics

Recruiting

A Phase 1/2 Study to Evaluate OTX-2002 in Patients With Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association With the MYC Oncogene (MYCHELANGELO I)

Hepatocellular Carcinoma | Solid Tumor | Liver Cancer | Hepatocellular Carcinoma Non-resectable | Hepatocellular Cancer | Hepatocellular Carcinoma Recurrent | Liver, Cancer of, Non-Resectable

United States, Hong Kong, Korea, Republic of, Singapore, Taiwan
Hunan Cancer Hospital

Completed

Circulating Tumor DNA (ctDNA)-Guided Late-Line Treatment in Patients With Late-Stage Breast Cancer (ACTDNAGLT)

Metastatic Breast Cancer | Circulating Tumor DNA | Gene Abnormality
Kathryn O'Connor

Completed

Structural and Functional Connectivity of Brainstem Monoamine Pathways in Treatment Resistant Depression (MAOI)

Treatment Resistant Depression

United States
University of Colorado, Denver

Completed

Effects of Ledipasvir/Sofosbuvir on the Pharmacokinetics and Renal Safety of Tenofovir Alafenamide (TAF)

Hepatitis C | HIV Coinfection

United States
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

Camrelizumab Combined With Apatinib Mesylate for Head and Neck Squamous Cell Carcinoma (IMplus)

Head and Neck Squamous Cell Carcinoma

China
The Catholic University of Korea

Completed

DPP4 Inhibitor and Coronary Atherosclerosis in Patients Receiving Insulin Therapy

Diabetes Mellitus

Korea, Republic of
Tesaro, Inc.

Completed

A Phase I/IIa Open-Label, Dose Escalation and Cohort Expansion Trial of Oral TSR-011 in Patients With Advanced Solid Tumors and Lymphomas

Solid Tumors | Lymphomas

United Kingdom, United States, Taiwan, Spain, Poland
Medical Practice Prof D. Ivanov

Completed

ARB, ACEi, DRi Effects on COVID-19 Course Disease (BIRCOV)

COVID-19 | Hypertension

Ukraine
Nahla H Tohami

Unknown

Effect of Sodium Glucose co Transporter 2 Inhibitor ( SGLT2) on Proteinuria in Diabetic Patients

Diabetic Nephropathies

Egypt
GlaxoSmithKline

Completed

Study To Evaluate Long Term Maintenance With TRIZIVIR After Boosted Protease Inhibitor (PI) Or Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) In HIV-1 Infected Adults

HIV Infections

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