Search clinical trials for: PI3K inhibitor BYL719

Total 64634 results

Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI); QIMR Berghofer Medical Research...

Completed

Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1 (CHMI-trans1)

Malaria

Netherlands
Masonic Cancer Center, University of Minnesota

Completed

T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Plasma Cell Neoplasm

United States
University College, London

Completed

Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma

Glioblastoma

United Kingdom
Helsinki University Central Hospital

Completed

A Study on Molecular Genetics of Drug Responsiveness in Essential Hypertension (GENRES)

Hypertension | Pharmacogenetics

Finland
University of Washington
National Cancer Institute (NCI)

Completed

Perioperative Therapy for Resectable Pancreatic Cancer

Adenocarcinoma of the Pancreas | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer

United States
Colgate Palmolive

Completed

Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)

Gingivitis | Dental Plaque

United States
Sunovion

Completed

Lurasidone - A 6-week Study of Patients With Bipolar I Depression (Add-on)

Bipolar Depression

United States, Czech Republic, India, France, Germany, Poland, Romania, Russian Federation, South Africa, Ukraine
University of Cincinnati
Patty Brisben Foundation For Women's Sexual Health

Unknown

Trigger Point Injections and Pelvic Rehabilitation for the Treatment of Pelvic Floor Myalgia and Sexual Pain

Dyspareunia

United States
Allergan

Withdrawn

Pharmacokinetics Study of Dapsone-Adapalene Fixed Combination Gel in Acne

Acne Vulgaris
Centers for Disease Control and Prevention
Ministry of Health and Population, Malawi

Completed

Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawi

Malaria, Falciparum

Malawi
Hoffmann-La Roche
Aspreva Pharmaceuticals

Completed

A Study of Mycophenolate Mofetil (CellCept) in Management of Patients With Lupus Nephritis.

Lupus Nephritis

Belgium, Germany, Italy, Spain, Canada, France, Portugal, United States, Greece, Mexico, United Kingdom, Australia, China, Hungary, Argentina, Brazil, Czech Republic
RWTH Aachen University
Air Liquide Santé International

Completed

Depth of Hypnosis and Postoperative Nausea and Vomiting During Xenon Anaesthesia (XABP)

Postoperative Nausea | Postoperative Vomiting | Depth of Anaesthesia | Anaesthetics Gases, Xenon | Anaesthetics Volatile, Sevoflurane

Germany
University Hospital, Aker
University of Oslo; AstraZeneca; Norwegian University of Science and Technology; Diakonhjemmet Hospital and other collaborators

Completed

Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants

Psychotic Disorders | Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorders

Norway
Pfizer

Terminated

Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asia

Malaria, Falciparum
Dalian Municipal Central Hospital

Recruiting

A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia

Hypotension Drug-Induced

China
H. Lee Moffitt Cancer Center and Research Institute
Turnstone Biologics, Corp.

Recruiting

TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC

Squamous Cell Carcinoma of Head and Neck | Metastatic Squamous Cell Carcinoma

United States
Roswell Park Cancer Institute

Not yet recruiting

Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Unresectable Triple-Negative Breast Carcinoma | Refractory Triple-Negative Breast Carcinoma

United States
Chinese PLA General Hospital
Zhejiang University

Recruiting

Combination of CAR-DC Vaccine and ICIs in Malignant Tumors

Lymphoma | Solid Tumor, Adult | EphA2 Overexpression | TP53 R273H | TP53 R175H | TP53 R248Q | TP53 R249S

China
University Hospital, Rouen

Recruiting

Opioid-Free Anesthesia in Cardiac Surgery (OFACS)

Anesthesia

France
University of Washington

Recruiting

Brentuximab Vedotin With or Without Nivolumab in Treating Patients With Relapsed or Refractory CD30+ Lymphoma

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma

United States
James Isaacs, MD

Suspended

Efficacy & Safety for LN144 With Pembrolizumab With High Risk Stage IIIb-dResectable Melanoma

Stage IIIB Melanoma | Stage IIIC Melanoma | Stage IIID Melanoma

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)-China Extension

Gastric Cancer | Gastroesophageal Junction Cancer

China
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)

Esophageal Squamous Cell Carcinoma (ESCC) | Gastroesophageal Junction Carcinoma (GEJC) | Esophageal Adenocarcinoma (EAC)

China, Canada, United States, Argentina, Belgium, Brazil, Chile, Czechia, Denmark, Estonia, France, Germany, Guatemala, Hong Kong, Hungary, Italy, Japan, Korea, Republic of, Mexico, Peru, Philippines, Portugal, Romania, Russian Federation and more
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease

Breast Cancer | Joint Pain

United States
Bangladesh College Of Physicians And Surgeons (BCPS)

Completed

Hydrodissection Between Normal Saline and a Combination of Triamcinolone Acetonide, Normal Saline, and Lidocaine in CTS

Carpal Tunnel Syndrome

Bangladesh
CHA University
Hanlim Pharm. Co., Ltd.

Completed

Comparison of Efficacy and Ocular Surface Assessment Between BRIDIN-plus and Combigan in Glaucoma or Ocular Hypertensive (BCT)

Glaucoma | Ocular Hypertensive

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Pembrolizumab With or Without Elbasvir/Grazoprevir and Ribavirin in Treating Patients With Advanced Refractory Liver Cancer

Stage IIIB Hepatocellular Carcinoma AJCC v7 | Stage IIIC Hepatocellular Carcinoma AJCC v7 | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Hepatitis C Infection | Stage IV Hepatocellular Carcinoma AJCC v7 | Stage III Hepatocellular Carcinoma AJCC v7 | Stage IIIA Hepatocellular... and other conditions

United States
University College, London
Pfizer; Cancer Research UK

Completed

Treatment of Patients With Diffuse Large B Cell Lymphoma Who Are Not Suitable for Anthracycline Containing Chemotherapy (INCA)

Diffuse Large B Cell Lymphoma

United Kingdom
Assiut University

Active, not recruiting

Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps.

Chronic Rhinosinusitis With Nasal Polyps | Montelukast

Egypt
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Drug Interaction Study Between Danicopan and Midazolam, Fexofenadine, and Mycophenolate Mofetil in Healthy Participants

Healthy

New Zealand
Dubai Health Authority

Unknown

Injection of Hyaluronic Acid Versus Corticosteroid for Treatment of Trigger Finger

Trigger Finger

United Arab Emirates
Kaohsiung Medical University

Unknown

Botulinum Toxins Intralesional Injection for Scar Pain

Hypertrophic Scar | Scar Keloid

Taiwan
Chong Kun Dang Pharmaceutical

Completed

Clinical Trial to Evaluate the Efficacy and Safety of CKD-495 Tablet

Gastritis

Korea, Republic of
Masonic Cancer Center, University of Minnesota

Terminated

T-Cell Depleted Double UCB for Refractory AML

Acute Myelogenous Leukemia | Refractory Acute Myelogenous Leukemia

United States
Seoul National University Bundang Hospital
Hanlim Pharm. Co., Ltd.

Unknown

S-amlodipine+Chlorthalidone vs S-amlodipine+Telmisartan in Hypertension

Essential Hypertension

Korea, Republic of
PH Research, S.L.

Completed

Nab-paclitaxel in Combination With Gemcitabine in Fragile Patients With Advanced Pancreatic Cancer (FRAGANCE)

Advanced Pancreatic Cancer

Spain
Taipei Veterans General Hospital, Taiwan

Completed

Efficacy of Combined Ultrasound Guided Steroid Injection and Splinting in Patients With Carpal Tunnel Syndrome

Carpal Tunnel Syndrome
New Mexico Cancer Care Alliance

Completed

Use of Hydralazine and Valproic Acid in Advanced Solid Tumor Malignancies

Lung Cancer

United States
Colgate Palmolive

Completed

The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and Gingivitis

Gingivitis | Dental Plaque

Puerto Rico
Hoffmann-La Roche

Terminated

A Study of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis.

Lupus Nephritis

China
Boehringer Ingelheim

Completed

Drug-drug Interaction of Empagliflozin (BI 10773) and Microgynon

Healthy

Germany
University Hospital, Ghent

Completed

Sevoflurane-Remifentanil Interaction: Multiple Response Surfaces, Validation of Calibration Stimuli, Validation of the Intraoperative Isobole Concept and Investigating Remifentanil Induced Opioid Tolerance

Anesthesia

Belgium
Medical University of Vienna

Completed

Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans

Healthy

Austria
Gildasio Castello de Almeida Junior
Hospital de Base

Completed

Evaluation of Tranilast to Treat Pterygium Before Excision (TPS)

Pterygium

Brazil
University of North Carolina, Chapel Hill

Recruiting

Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Stroke | Brain Ischemia | Brain Injuries, Traumatic | Heart Arrest | Intracranial Hemorrhages | Brain Hypoxia | Coma | Hypoxia-Ischemia, Brain | Persistent Vegetative State | Brain Injuries, Acute

United States
1ST Biotherapeutics, Inc.
Merck Sharp & Dohme LLC

Recruiting

A Phase I/II, Open-label Study to Investigate the Safety, Tolerability, PK, and Preliminary Efficacy of FB849

Advanced Solid Tumor

United States
Dwight Owen
National Cancer Institute (NCI)

Recruiting

PBF-1129 and Nivolumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States
Fondazione Policlinico Universitario Agostino Gemelli...
IRCCS Policlinico S. Donato; Centro Cardiologico Monzino

Recruiting

Prognostic Value of Precision Medicine in Patients With MINOCA (PROMISE Trial). (PROMISE)

Myocardial Infarction With Non-Obstructive Coronary Arteries

Italy
Prof. Janet Dunn
King's College Hospital NHS Trust; University of Manchester; University of Birmingham and other collaborators

Recruiting

Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes (REPAIR-MDS)

Myelodysplastic Syndromes (MDS)

United Kingdom
Xiaoli Fan

Recruiting

A Randomised Clinical Trial Assessing the Efficacy and Safety of Mycophenolate Mofetil Versus Azathioprine for Induction of Remission in Treatment Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome

Autoimmune Hepatitis | Primary Biliary Cirrhosis

China

Search clinical trials for: PI3K inhibitor BYL719

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