Search clinical trials for: PO Placebo

Total 53918 results

University Health Network, Toronto
Merck Sharp & Dohme LLC

Completed

The ACTIVATE (Adoptive Cell Therapy InVigorated to Augment Tumor Eradication) Trial (ACTIVATE)

Advanced Ovarian Cancer | Malignant Melanoma

Canada
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (TRANSFORM-2)

Treatment-resistant Depression

United States, Poland, Germany, Spain, Czechia
Bausch Health Americas, Inc.

Completed

Effects of MNTX on CYP450 2D6 in Metabolizers of Dextromethorphan

Healthy Adults

United States
Mark Ware

Terminated

Genetic Variants Associated With Low Back Pain and Their Response to Treatment With Duloxetine or Propranolol

Low Back Pain

Canada
Weill Medical College of Cornell University

Withdrawn

Rituximab and Dexamethasone Followed by Mycophenolate Mofetil or Placebo in Patients With Immune Thrombocytopenia

Immune Thrombocytopenia
Amphastar Pharmaceuticals, Inc.

Terminated

Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.

Asthma

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler (Puffer) in Adolescents and Adults Who Have Asthma That is Not Controlled by High Dose Inhaled Corticosteroid Asthma Medications

Asthma

United States, Australia, Bulgaria, Canada, Croatia, Germany, Greece, Hungary, Ireland, Israel, New Zealand, Poland, Romania, Russian Federation, Serbia, South Africa, Spain, Ukraine, United Kingdom
Emory University

Completed

Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery (SITACABG NonDM)

Coronary Artery Disease

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse

Cocaine Dependence

United States
St. Renatus, LLC
Rho, Inc.; Triligent International

Completed

Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth in Adults

Anesthesia

United States
Sanofi

Completed

Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis (SARILNIUSATURN)

Uveitis

Italy, Turkey, Spain, United States, Czechia, France
Bristol-Myers Squibb

Completed

Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986141 in Healthy Subjects

Thrombosis

United States
University of Minnesota

Withdrawn

Local Anesthesia and Analgesics in Endodontic Pain (LAAEP)

Odontalgia

United States
GlaxoSmithKline

Withdrawn

A Study Comparing the Closed Triple Therapy, Open Triple Therapy and a Dual Therapy for Effect on Lung Function in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Canada, Germany
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Vismodegib in Treating Patients With Advanced Stomach Cancer or Gastroesophageal Junction Cancer

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Adenocarcinoma of the Stomach | Stage IIIA Gastric Cancer | Stage IIIB Gastric Cancer | Stage IIIC Gastric Cancer

United States
Diskapi Yildirim Beyazit Education and Research...

Unknown

Postoperative Analgesia in Laminectomy ((PAL))

Postoperative Pain | Postoperative Laminectomy Pain
Seoul National University Bundang Hospital
Yuhan Corporation

Completed

Study Design of 'Influence of Sarpogrelate in Patients With Renal Impairment or Diabetes Mellitus' Study (SERENADE)

Coronary Artery Disease | Diabetes Mellitus | Renal Insufficiency, Chronic

Korea, Republic of
Orexigen Therapeutics, Inc

Completed

A Safety and Efficacy Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects

Obesity | Overweight

United States
US Department of Veterans Affairs

Completed

Nicotine Patch Pretreatment for Smoking Cessation in PTSD

Tobacco Use Disorder | Stress Disorders, Posttraumatic

United States
Medical University of Vienna

Terminated

Role of Nitric Oxide in Optic Nerve Head Blood Flow Regulation During Experimental Increase of Intraocular Pressure in Healthy Humans

Healthy

Austria
Mansoura University

Completed

Are There Protective Effects of Antioxidants, Calcium Channel Blocker and Angiotensin Receptor Blocker Against Extracorporeal Shockwaves Lithotripsy Induced Renal Injury? (SWL)

Kidney Calculi

Egypt
Sunovion

Completed

A Comparison of Study Drug With Placebo and Haloperidol in Patients With Schizophrenia

Schizophrenia

United States
National Taiwan University Hospital
Cathay General Hospital

Unknown

Pregabalin for the Treatment of Uremic Pruritus

Uremic Pruritus

Taiwan
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma

Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Epithelial Mesothelioma | Sarcomatous Mesothelioma | Localized Malignant Mesothelioma

United States
Medical University of Lodz

Unknown

Usefulness of Exhaled Breath Condensate for Evaluation of Markers of Airway Inflammation in Children With Asthma

Asthma

Poland
AstraZeneca

Completed

A Study in Asthmatic Children (6 to <12 Yrs) Comparing Single Doses of Formoterol and Foradil® Evaluating Efficacy (CHASE 2)

Asthma

United States, South Africa, Hungary, Bulgaria, Czech Republic, Poland
Radboud University Medical Center

Unknown

Perioperative Δ9-THC for Postsurgical Pain (NamiSur)

Pain

Netherlands
Pfizer

Completed

Study of Safety and Efficacy of PF-04991532 in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Taiwan, Slovakia, Mexico, Canada, Hungary
University of Aarhus
Tandlaegeforeningen, Calcin fonden

Completed

Assessment of the Operative Course in Connection With Removal of Lower Third Molars

Inflammation | Postoperative Pain

Denmark
Tehran University of Medical Sciences

Completed

Pioglitazone as an Adjunct for Moderate to Severe Depressive Disorder

Major Depressive Disorder

Iran, Islamic Republic of
Turku University Hospital

Completed

Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol

Pharmacokinetics | Pharmacodynamics

Finland
Pfizer

Completed

Clinical Study Assessing a New Scale to Measure Onset of Action in Generalized Anxiety Disorder

Anxiety Disorders

United States
Glostrup University Hospital, Copenhagen

Terminated

The Effect of Gabapentin, Ketamine and Dexamethasone on Pain and Opioid Requirements After Hip Surgery

Pain, Postoperative

Denmark
Universidade Federal do Para

Not yet recruiting

Pregabalin Gel in Reducing Post-operative Tooth Sensitivity Surgery Caused by Bleaching With 35% Hydrogen Peroxide

Tooth Bleaching | Sensitivity, Tooth

Brazil
Boehringer Ingelheim

Recruiting

A Study in Healthy Men to Test How Well Multiple Doses of BI 1839100 Are Tolerated and How BI 1839100 Influences the Amount of Other Medicines in the Blood

Healthy

Netherlands
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated Patients (SEEDS)

Analgesia | Ketamine | Dexmedetomidine | Mechanical Ventilation | Intensive Care Units

China
Qianfoshan Hospital

Not yet recruiting

Clinical Study of the Effect of Methylprednisolone Combined

Methylprednisolone;Dihydroxypropyltheophylline;One Lung Ventilation;Respiratory Dynamics
University of Rochester NCORP Research Base
National Cancer Institute (NCI)

Recruiting

Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors

Be Diagnosed With Cancer and Have Completed Systemic Therapy

United States
University of Calgary

Recruiting

Treating Postictal Symptoms Using Ibuprofen and Nifedipine

Epilepsy | Epilepsies, Partial

Canada
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)-China Extension

Gastric Cancer | Gastroesophageal Junction Cancer

China
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)

Esophageal Squamous Cell Carcinoma (ESCC) | Gastroesophageal Junction Carcinoma (GEJC) | Esophageal Adenocarcinoma (EAC)

China, Canada, United States, Argentina, Belgium, Brazil, Chile, Czechia, Denmark, Estonia, France, Germany, Guatemala, Hong Kong, Hungary, Italy, Japan, Korea, Republic of, Mexico, Peru, Philippines, Portugal, Romania, Russian Federation and more
Azurity Pharmaceuticals

Completed

An Abuse Potential Study of Orally Administered HORIZANT in Healthy, Non-dependent, Recreational Drug Users

Abuse Potential

United States
UdonThani Hospital

Active, not recruiting

Effects of Cervical Lidocaine Spray on Pain Relief During Manual Vacuum Aspiration

Pain, Procedural | Lidocaine | Obstetric Surgical Procedures

Thailand
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Prometheus Laboratories; Key Biologics, LLC; Adelson...

Active, not recruiting

Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma

Melanoma

United States
ViiV Healthcare

Completed

Study to Evaluate Pharmacokinetic (PK), Safety and Tolerability of Cabotegravir (CAB) 400 Milligrams Per Milliliter (mg/mL) Formulation in Healthy Adult Participants

HIV Infections

United States, New Zealand
Bayer

Completed

Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold

Common Cold | Tonsillitis | Pharyngitis

Ukraine, Russian Federation
ZetrOZ, Inc.

Completed

Sustained Acoustic Medicine for Knee Osteoarthritis Pain

Knee Osteoarthritis

United States
Sanofi
Regeneron Pharmaceuticals

Completed

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Hypercholesterolaemia

Czechia, France, Denmark, Netherlands, Austria, Mexico, Spain, United States, Argentina, Brazil, Bulgaria, Canada, Finland, Hungary, Italy, Lebanon, Norway, Poland, Russian Federation, Slovenia, South Africa, Sweden, Taiwan, Turkey
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Assess the Efficacy and Safety of Beclomethasone Dipropionate in Adolescent and Adult Patients 12 Years of Age and Older With Persistent Asthma

Persistent Asthma

United States
Uppsala University

Completed

The Precision Hypertension Care Study (PHYSIC)

Hypertension

Sweden

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