Search clinical trials for: PR4 LDV/SOF SMV 12 wk

Total 65 results

Humanity and Health Research Centre
Beijing 302 Hospital; Nanfang Hospital of Southern Medical University

Recruiting

Switching Regimen in Treating Cirrhotic HCV GT1b Subjects (SWITCH-1)

Chronic Hepatitis C Infection

China
Hunan Province Tumor Hospital

Recruiting

The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC (PROFILE)

Non Small Cell Lung Cancer | EGF-R Positive Non-Small Cell Lung Cancer | RET Gene Mutation | MET Amplification

China
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Cardiac Safety of a Single Dose of AL-335 Administered on a Background of Simeprevir and Odalasvir and of Repeated Doses of Odalasvir Administered Alone in Healthy Participants

Healthy

United States
Janssen Sciences Ireland UC

Completed

A Study to Investigate the Pharmacokinetic Interactions Between Simeprevir and Ledipasvir in a Treatment Regimen Consisting of Simeprevir, Sofosbuvir, and Ledipasvir in Treatment-naive Participants With Chronic Hepatitis C Virus Genotype 1 Infection

Hepatitis C, Chronic

Belgium
Gaziosmanpasa Research and Education Hospital

Recruiting

Pectopexy Surgery Without Mesh

Pelvic Organ Prolapse

Turkey
Janssen Research & Development, LLC

Completed

Study to Investigate the Pharmacokinetic Interaction Between 2 Direct Acting Antiviral Agents Odalasvir and AL-335 and Between 3 Direct Acting Antiviral Agents Simeprevir, Odalasvir and AL-335 at Steady State in Healthy Japanese Participants

Healthy

United Kingdom
Humanity and Health Research Centre
Emory University; Beijing 302 Hospital

Completed

Triple DAAs Regimen in Treating Non-cirrhotic HCV GT1b Subjects

Chronic Hepatitis C Infection

China
Alios Biopharma Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of the Combination of AL-335, Odalasvir, and Simeprevir

Chronic Hepatitis C

New Zealand, Moldova, Republic of, Mauritius, United Kingdom
Janssen Pharmaceutical K.K.

Completed

A Study to Investigate the Safety, Pharmacokinetics, and Efficacy of Combination Treatment of AL-335, Odalasvir, and Simeprevir in Japanese Participants With Chronic Hepatitis C Genotype 1 or 2 Virus Infection, With or Without Compensated Cirrhosis Who Are Direct Acting Antiviral Treatment-naive

Hepatitis C, Chronic

Japan
Neumedicines Inc.
National Cancer Institute (NCI)

Unknown

NM-IL-12 in Cutaneous T-Cell Lymphoma (CTCL) Undergoing Total Skin Electron Beam Therapy (TSEBT)

Mycosis Fungoides | Sézary Syndrome | Cutaneous T Cell Lymphoma (CTCL)

United States
Laboratorio Avi-Mex, S.A. de C.V.
National Council of Science and Technology, Mexico; Instituto Nacional de Enfermedades...

Completed

Phase II/III Study of the AVX/COVID-12 Vaccine Against COVID-19 Applied as a Booster.

SARS-CoV-2 Infection

Mexico
Janssen Research & Development, LLC

Completed

A Pharmacokinetic Interaction Study Between Odalasvir, Given as a Single Agent or in Combination With Simeprevir, and Dabigatran Etexilate Mesylate in Healthy Participants

Healthy

United States
Oxford University Hospitals NHS Trust
National Institute for Health Research, United Kingdom; Heart Research UK

Completed

A Pilot Study of Interventricular Septal Puncture for Cardiac Resynchronization Therapy to Treat Heart Failure (LV-CONSEPT)

Heart Failure

United Kingdom
Aga Khan University

Unknown

Comparison of Vitamin B12 Supplementation to Selective Serotonin Reuptake Inhibitor (SSRI) Versus SSRI Antidepressant Treatment Alone

Major Depressive Disorder

Pakistan
Hoffmann-La Roche

Completed

A Study of Valcyte (Valganciclovir) CMV Prophylaxis After Renal Transplantation

Cytomegalovirus Infections

Germany, Austria
Weill Medical College of Cornell University

Terminated

Use of Cast Iron Pots to Improve Maternal Anemia

Iron-deficiency Anemia

United States
Dr. Yoram Shir
National Cancer Institute (NCI); McGill University; Louise & Alan Edwards Foundation

Terminated

The Effect of Soy Protein on Post- Breast Cancer Surgery Pain

Pain | Breast Cancer | Chronic Disease

Canada
Gaziosmanpasa Research and Education Hospital

Recruiting

Evaluation of the Results of Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh in the Surgical Treatment of Pelvic Organ Prolapse

Pelvic Organ Prolapse

Turkey
Mustafa Khasraw, MBChB, MD, FRCP, FRACP

Completed

DC Migration Study for Newly-Diagnosed GBM (ELEVATE)

Glioblastoma | Glioblastoma Multiforme | Giant Cell Glioblastoma | Astrocytoma, Grade IV

United States
Assiut University

Completed

Hematologic Profile, Vit. B12 and Folic Acid in Cirrhotics Received Sofosbuvir and Daclatasvir With or Without Ribavirin

Liver Cirrhoses | Chronic Hepatitis c | Directly Acting Antivirals

Egypt
University of Southern California

Completed

Effects of Vitamin B12 Treatment in Singers

Vitamin B 12 Deficiency

United States
Gilead Sciences

Terminated

A Registry for Adolescent and Pediatric Participants Who Received a Gilead Hepatitis C Virus Direct Acting Antiviral (DAA) in Gilead-Sponsored Chronic Hepatitis C Infection Trials

Hepatitis C Virus Infection

United States, United Kingdom, Australia, Germany, Italy, New Zealand, Belgium, Poland, Russian Federation
Harvard School of Public Health (HSPH)
Unity Health Toronto; University of Toronto

Completed

Air Pollution, Epigenetics and Cardiovascular Health: A Human Intervention Trial (EPI-Air)

Inflammation | Heart Rate Variability | Heart Rate

Canada
Eric Thompson, M.D.
National Cancer Institute (NCI); National Institutes of Health (NIH); Annias...

Terminated

Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens (PERFORMANCE)

Glioblastoma | Glioblastoma Multiforme

United States
Valme University Hospital
Hospital General Universitario Elche; Hospital del SAS de Jerez; Clinica Universidad... and other collaborators

Completed

Efficacy and Safety of Therapy Against HCV Based on Direct-acting Antivirals in Real-life Conditions (FPSMON201401)

Chronic Hepatitis C Infection

Spain
Universidade Estadual de Maringá

Unknown

Efficacy of N-Acetyl-Cysteine in Bipolar Disorder and Tobacco Use Disorder (NACBD)

Bipolar Disorder

Brazil
Sohag University

Completed

Evaluation of the Clinical Efficacy and Safety of Dapoxetine, Combined Dapoxetine With Folic Acid and Combined Dapoxetine With Vitamin B12 in Treatment of Patients With Premature Ejaculation (PE)

Premature Ejaculation

Egypt
Annick Desjardins, MD
Celldex Therapeutics

Active, not recruiting

DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab (DERIVe)

Glioblastoma

United States
Moshe Flugelman

Terminated

Examining B12 Deficiency Associated With C677T Mutation on MTHFR Gene in Terms of Commonness and Endothelial Function

B12 Deficiency Combined With C677T Mutation on MTHFR Gene

Israel
The University of Hong Kong

Recruiting

Nurse-led Alcohol Brief Intervention Plus Mobile Personalized Chat-based Support on Reducing Alcohol Use in University Students

Alcohol Misuse

Hong Kong
Nucleo De Pesquisa E Desenvolvimento De Medicamentos...

Unknown

Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics

Schizophrenia | Oxidative Stress | Drug Induced Movement Disorder, Unspecified

Brazil
Genzyme, a Sanofi Company
Bayer

Completed

A Phase II Study Comparing Low- and High-Dose Alemtuzumab and High-Dose Rebif® in Patients With Early, Active Relapsing-Remitting Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting

United States, Russian Federation, Poland, Croatia, United Kingdom
Mustafa Khasraw, MBChB, MD, FRCP, FRACP

Terminated

Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated Glioma (I-ATTAC)

Glioblastoma

United States
NSABP Foundation Inc
Eli Lilly and Company; Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer Patients

Metastatic Colorectal Cancer

United States
Tampere University Hospital

Terminated

Intracoronary Administration of Levosimendan in Cardiac Surgery Patients

Myocardial Stunning

Finland
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Completed

Evaluate the Neuroprotective Effect of Vitamin B6 and Vitamin B12 Against Vincristine Induced Neurotoxicity in Acute Lymphoblastic Leukaemia Patients

Acute Lymphoblastic Leukaemia | Vincristine Induced Neurotoxicity

Bangladesh
Johns Hopkins Bloomberg School of Public Health
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Extended Infant Post-exposure Prophylaxis With Antiretrovirals to Reduce Postnatal HIV Transmission

HIV Infections

Malawi
Fundación Leucemia y Linfoma, Spain
Roche Pharma AG

Completed

Rituximab and CVP Plus Interferon for Follicular Non Hodgkins Lymphoma (NHL) (LNH-Pro-05)

Non-Hodgkin's Lymphoma

Spain
Yasoo Health

Completed

Efficacy of a Novel Multivitamin-Mineral Supplement in Preventing Vitamin Deficiency in Postoperative Bariatric Patients

Bariatric Surgery Candidate

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Completed

Neuroprotective Effect of Vitamin B12 and Vitamin B6 Against Vincristine Induced Peripheral Neuropathy

Vincristine Induced Peripheral Neuropathy (VIPN)

Bangladesh
PATH
University of Maryland; Center for Vaccine Development - Mali

Completed

Immune Response to Rotavirus Vaccine After a Supplemental Dose Given at 9 Months of Age With Local EPI Vaccines in Mali

Diarrhea Rotavirus

Mali
Dalia Salah Saif

Unknown

Platelet Rich Plasma Injection Versus Surgical and Medical Treatment of Mild-moderate Carpel Tunnel Syndrome.

Carpal Tunnel

Egypt
Spectrum Pharmaceuticals, Inc

Completed

Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Lymphoma, B-Cell

United States
Wayne State University
Abbott

Terminated

Addition of Modulators of Homocysteine to Adalimumab Therapy in the Treatment of Moderate to Severe Plaque Psoriasis

Psoriasis
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

An Open Label Demonstration Project and Phase II Safety Study of Pre-Exposure Prophylaxis

HIV Infection

United States
Locus Biosciences
Parexel

Recruiting

A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial) (ELIMINATE)

Urinary Tract Infections

United States
Janssen Research & Development, LLC

Completed

To Evaluate the Effects of Odalasvir and AL-335 With Simeprevir on the Single-Dose Pharmacokinetics of Ethinylestradiol and Drospirenone in Healthy Female Participants

Healthy

United States
Acrotech Biopharma Inc.

Completed

Study of Pralatrexate in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Cutaneous T-cell Lymphoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

Comparison of Three Anti-HIV Regimens to Prevent Nevirapine Resistance in Women Who Take Nevirapine During Pregnancy

HIV Infections

Tanzania, Haiti, Malawi, South Africa, India, Uganda
RemeGen Co., Ltd.

Recruiting

Neoadjuvant Study of DV in Combination Toripalimab or Sequence Chemotherapy in HR-negative, HER2 Low-expressing Breast Cancer

Breast Cancer

China

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