Search clinical trials for: PRO-143 Ophthalmic Solution

Total 1963 results

Oculis

Completed

OCS-01 in Treating Inflammation and Pain in Post-cataract Patients (SKYGGN)

Pain, Postoperative | Inflammation Corneal

United States
Peptomyc S.L.

Recruiting

Study to Evaluate the Safety, PK, and Efficacy of the Myc Inhibitor OMO-103 Administered iv in Patients With PDAC (OMO-103-02)

Metastatic Pancreatic Cancer

Spain
Yael P Mosse
Novartis Pharmaceuticals; Foundation Medicine

Terminated

Next Generation Personalized Neuroblastoma Therapy (NEPENTHE)

Cancer | Neuroblastoma

United States
Democritus University of Thrace

Completed

Blurring Strength & Aberrometric Changes Following Corneal Cross-linking (CxL) and CxL Combined With Photorefractive Keratectomy (PRK) in Keratoconus

Keratoconus

Greece
Laboratorios Sophia S.A de C.V.

Completed

Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087LATAMFIV) (087LATAMFIV)

Dry Eye Syndrome

Mexico
Nicox Ophthalmics, Inc.

Recruiting

Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution (Whistler)

Open Angle Glaucoma

United States
Military Hospital of Tunis

Completed

Treatment of Corneal Infiltrates Secondary to Epidemic Keratoconjunctivitis

Adenoviral Keratoconjunctivitis

Tunisia
Allergan

Completed

Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease

Dry Eye Syndromes

United States
Medical University of Vienna

Completed

Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Physiology | Retina

Austria
CT Glaucoma Associates

Recruiting

How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?

Glaucoma, Open-Angle | Glaucoma; Drugs

United States
L.V. Prasad Eye Institute
Allergan

Recruiting

CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops

Congenital Hereditary Endothelial Dystrophy of Cornea

India
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Active, not recruiting

A Phase III Clinical Study of the Efficacy and Safety of Two Low-concentration Atropine Sulfate Eye Drops (Mini-CHAMP)

Myopia

China
Hai Yen Eye Care
Brien Holden Vision

Completed

Evaluation of Short Term Use of Experimental Eye Drops BHVI2, 0.02% Atropine and BHVI2 Plus 0.02% Atropine Eye Drops

Myopia

Vietnam
Campus Bio-Medico University
University of Padova; University of Genova

Completed

Cyclosporin A Eye Drop Treatment in Vernal Keratoconjunctivitis

Vernal Keratoconjunctivitis

Italy
Allergan

Completed

Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005%

Ocular Hypertension | Glaucoma

United States
Boehringer Ingelheim

Completed

This Study in Healthy Men and Women Tests How the Body Takes up BI 409306

Healthy

Germany
Mahmoud Mohammed Mahmoud Nasef

Completed

Evaluation of Anterior Repositioning Guided Splint Combined With or Without I Platelet-rich Fibrin

Temporomandibular Joint Disorders

Egypt
Merck Sharp & Dohme LLC

Completed

Safety and Pharmacokinetics of Intravenous and Oral Posaconazole in Immunocompromised Children (MK-5592-097)

Neutropenia
Samsung Medical Center
Janssen, LP

Terminated

Evaluation of Antifungal Prophylaxis on Graft-versus-host Disease (GVHD) Patients (ITRAG)

Graft vs Host Disease

Korea, Republic of
University of Maryland, Baltimore

Completed

Itraconazole Oral Absorption

Fungal Infection

United States
Small Pharma Ltd

Completed

SPL026 (DMT Fumarate) in Healthy Subjects and MDD Patients

Major Depressive Disorder

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

An Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK1265744 Administered as a Single Oral Dose and a Study to Describe the Pharmacokinetics of a Supratherapeutic Dose of GSK1265744 in Healthy Adult Subjects

HIV-associated Lipodystrophy Syndrome

United States
Centre Oscar Lambret
Institut National de la Santé Et de la Recherche Médicale, France; National... and other collaborators

Active, not recruiting

Evaluation of Sentinel Node Policy in Early Stage Endometrial Carcinomas at Intermediate and High Risk of Recurrence. (SENTIRAD)

Endometrial Carcinoma

France
Merck KGaA, Darmstadt, Germany

Completed

Supplementation of VigantOL® Oil Versus Placebo as Add-on in Patients With Relapsing Remitting Multiple Sclerosis Receiving Rebif® Treatment (SOLAR)

Relapsing-Remitting Multiple Sclerosis

Germany, Estonia, Latvia, Lithuania, Finland, Austria, Denmark, Netherlands, Portugal, Switzerland, Norway, Italy
Biogen

Withdrawn

Transition to Peginterferon Beta-1a (BIIB017) From Subcutaneous Interferon Therapy (Frequency)

Relapsing Multiple Sclerosis
Ohio State University
University of California, Berkeley; Stanford University; University of Houston; Indiana University and other collaborators

Withdrawn

Delaying the Onset of Nearsightedness Until Treatment Study (DONUT)

Myopia
Memorial Sloan Kettering Cancer Center
Comprehensive Cancer Centre The Netherlands

Recruiting

Quality of Life (QoL) Assessment in Cancer Patients and Survivors With Dermatologic Conditions Using Dermatologic QoL Instruments

Cancer | Dermatologic Conditions

United States
Makassed General Hospital

Completed

Nebulized Epinephrine vs. Salbutamol in Bronchiolitis Among Children

Respiratory Distress Score

Lebanon
Credit Valley EyeCare
Canadian Glaucoma Clinical Research Council

Unknown

Effect of Prophylactic Aqueous Suppression on Hyperencapsulation of Ahmed Glaucoma Valves

Glaucoma

Canada
Zhongshan Ophthalmic Center, Sun Yat-sen University

Unknown

Prospective Study of Deep Anterior Lamellar Keratoplasty Using Acellular Porcine Cornea

Corneal Transplantation

China
Medical University of Vienna

Completed

Local Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers

Dry Eye Syndromes

Austria
Tampere University Hospital

Terminated

Intracoronary Administration of Levosimendan in Cardiac Surgery Patients

Myocardial Stunning

Finland
National Institute of Allergy and Infectious Diseases...

Completed

H5 Vaccine Alone or With Adjuvant in Healthy Adults

Influenza

United States
UCB Pharma

Completed

Magnetic Resonance Image Verified Early Response to Certolizumab Pegol in Subjects With Active Rheumatoid Arthritis (RA) (MARVELOUS)

Rheumatoid Arthritis

Denmark, Netherlands, Poland, Sweden
Laboratorios Sophia S.A de C.V.

Completed

Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK) (CONFORTK)

Primary Open Angle Glaucoma | Ocular Hypertension
Sanofi
Population Health Research Institute

Completed

The ORIGIN Trial (Outcome Reduction With Initial Glargine Intervention) (ORIGIN)

Diabetes Mellitus, Non-Insulin-Dependent

United States, France, Brazil, Poland, Romania, Germany, Italy, Netherlands, Spain, Sweden, Switzerland, Turkey, India, Philippines, Russian Federation, Slovakia, Mexico, Argentina, Croatia, Austria, Denmark, Finland, Hungary, Lithuania, Norw... and more
Forest Laboratories
Ironwood Pharmaceuticals, Inc.

Completed

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)

Functional Constipation in Children Ages 6-17 Years

United States, Canada
Università degli Studi di Brescia

Completed

NSAIDs and PGE2 Levels in Vitrectomy Patients

Vitreous Inflammation
Lin Jiacheng

Unknown

Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis

Periapical Diseases

China
Robert Bok, MD, PhD
National Cancer Institute (NCI)

Recruiting

Hyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant Glioma

Adult Gliomas, Mixed

United States
NHS Greater Glasgow and Clyde
Glasgow Caledonian University; Lamellar Biomedical Ltd; Robertson Centre for...

Unknown

LAMELLEYE for the Treatment of Dry Eye Symptoms in pSS Patients

Dry Eye Syndromes | Primary Sjögren Syndrome
Fondation Ophtalmologique Adolphe de Rothschild
Ecouter Voir; Hoya Lens France

Recruiting

Myopia Control in Children: Comparison of Defocus Incorporated Multiple Segments® Lenses Versus Atropine 0.05% Eyedrops (ATROSMART)

Myopia

France
University Hospital of Patras

Completed

Effect of Topical and Oral Diclofenac on Pain Related to Intravitreal Injections

Pain

Greece
Alcon Research

Completed

Study of Efficacy and Safety of Vigadexa in Treating Inflammation and Infection Post-cataract Surgery

Cataract

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Phase 1 Study of Ertugliflozin in Healthy Male Participants (MK-8835-020)

Type 2 Diabetes Mellitus
Novartis Pharmaceuticals

Active, not recruiting

Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. (V-Mono)

Hypercholesterolemia

United States, Germany, Hungary, Colombia, Mexico
National University of Malaysia
Santen Pharmaceutical Co., Ltd.

Unknown

Intracameral Levofloxacin (0.5%) vs Intracameral Cefuroxime

Endophthalmitis Postoperative

Malaysia
Universidade Federal Fluminense

Recruiting

Different Endodontic Treatment Techniques in Postoperative Symptoms, Apical Repair, Longevity of Rehabilitations, and Oral Health-related Quality of Life

Edema | Postoperative Pain | Endodontically Treated Teeth | Photochemotherapy

Brazil
Eyenovia Inc.

Completed

Study of the Safety, Efficacy and PK of EYN-1601 in Dilation of the Pupil

Mydriasis

United States
Boehringer Ingelheim

Terminated

Study to Assess the Efficacy of Ipratropium Bromide Associated With High Dose Salbutamol by Repeated Nebulisation Versus Repeat Nebulisation of Salbutamol Alone, in Acute Asthmatic Attacks in Young Children

Asthma

3

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