Search clinical trials for: Period 1: AT-527 550 mg

Total 318 results

Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Effect of Carbamazepine on the Pharmacokinetics (PK) of AT-527

Healthy Volunteer Study

Canada
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Study of AT-527 in Healthy Subjects (R07496998)

Healthy Volunteer Study

Canada
CymaBay Therapeutics, Inc.

Completed

Study to Evaluate the Effects of MBX-8025 in Patients With HoFH

Homozygous Familial Hypercholesterolemia

Canada, France, Netherlands, Norway
LG Life Sciences

Completed

Safety and Pharmacokinetics Between Fixed-dose Combination VR 160/20 mg and Co-administration of Diovan® (Valsartan) Film-coated Tablet 160 mg and Crestor® (Rosuvastatin) 20 mg

Hypertension | Hyperlipidemia

Korea, Republic of
Atea Pharmaceuticals, Inc.

Completed

Drug-drug Interaction Study of Ruzasvir and Bemnifosbuvir (AT-527)

Healthy Volunteer Study

Canada
MedImmune LLC

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single-Dose Subcutaneous Administration of MEDI-528

Healthy

United States
MedImmune LLC

Completed

Study to Evaluate the Safety, Tolerability,Immunogenicity, and Pharmacokinetics of MEDI-528 in Healthy Adult Volunteers

Asthma

United States
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)

Healthy Volunteer Study

Canada
Chimerix

Terminated

Pilot/Ph I Safety and Efficacy of ODSH in Protein Losing Enteropathy Secondary to Single Ventricle Palliative Surgery

Protein Losing Enteropathy

United States
Pfizer

Completed

A Study To Observe Safety And Concentrations Of PF-05297909 And Proteins In Both Blood And Cerebrospinal Fluid After A Single Dose Of PF-05297909 In Healthy Adults

Healthy

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Completed

Estimation of Paracetamol in Urine to Assess the Diurnal Variation

Diurnal Variation of Paracetamol Excretion

Bangladesh
MedImmune LLC
AstraZeneca

Terminated

A Safety and Tolerability Study of MEDI-570 in Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic

United States, Mexico, Peru, South Africa, Canada
Organon and Co

Completed

Study to Evaluate Potential Decrease in Hospitalization Events, Time Between Events, and Increasing Longevity in Patients With Symptomatic Heart Failure (0954-948)

Heart Failure
Innate Pharma

Completed

Efficacy Study of Anti-KIR Monoclonal Antibody as Maintenance Treatment in Acute Myeloid Leukemia (EFFIKIR) (EFFIKIR)

Acute Myeloid Leukemia

France
Ardea Biosciences, Inc.

Completed

Lesinurad Tablet Bioequivalence

Healthy

United States
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Drug-drug Interaction Study of Midazolam and AT-527 (R07496998)

Healthy Volunteer Study

Canada
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Entecavir and Pegasys Sequential Therapy Versus Pegasys for HBeAg Positive Chronic Hepatitis B

Hepatitis B, Chronic

Taiwan
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

Healthy

United States
GlaxoSmithKline

Completed

A Pharmacokinetic Study to Compare Sustained Release and Standard Paracetamol Formulations.

Pain

United States
Michigan State University
PriCara, Unit of Ortho-McNeil, Inc.

Completed

Urinary Bactericidal Activity of 4 Doses of Levofloxacin Against Fluoroquinolone-Resistant E. Coli

Healthy Volunteers

United States
Handok Inc.

Completed

Dose Proportionality Study Comparing Amaryl-M 1/500 mg and Amaryl-M 2/500 mg

Healthy
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Entecavir and Pegasys Sequential Therapy Versus Pegasys for HBeAg Negative Chronic Hepatitis B

Hepatitis B, Chronic

Taiwan
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949

Healthy Subjects

Netherlands
ViiV Healthcare

Completed

A Study of the Relative Bioavailability of BMS-626529 Administered as BMS-663068 From 150mg Low-dose Extended-release Tablets Compared to 600mg Reference Extended-release Tablets in Healthy Subjects

Infection, Human Immunodeficiency Virus

United States
Janssen Research & Development, LLC

Completed

Study of Paliperidone Palmitate 3 Month and 1 Month Formulations for the Treatment of Patients With Schizophrenia

Schizophrenia

France, United States, China, Spain, Argentina, Mexico, Portugal, Bulgaria, Germany, Poland, Russian Federation, Ukraine, Japan, Greece, Taiwan, Korea, Republic of, Canada, Czech Republic, Brazil, Hungary, Austria, Sweden, Romania, Sl... and more
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

Healthy Volunteers

United States
Janssen Research & Development, LLC

Completed

A Study of Paliperidone Palmitate 6-Month Formulation

Schizophrenia

United States, Korea, Republic of, Hong Kong, Taiwan, Malaysia, Czechia, Poland, Brazil, India, Spain, Argentina, Bulgaria, Turkey, Russian Federation, Ukraine, Hungary, South Africa, Mexico, Australia, France, Italy
Otsuka Pharmaceutical Co., Ltd.

Completed

A Safety Evaluation Trial of TEV-48125 Self-administered in Migraine Patients

Migraine

Japan
Laboratorios Silanes S.A. de C.V.

Recruiting

Oral Combination of Glimepiride/Vildagliptin/Metformin in Patients With T2D and Dual Treatment Failure

Type 2 Diabetes

Mexico
Pfizer

Completed

Drug Drug Interaction Study Evaluating the Effect of Fluvoxamine or Fluconazole on PK and Safety of PF-04965842.

Dermatitis, Atopic

Belgium
Kaohsiung Veterans General Hospital.

Completed

Comparing the Efficacy of Reverse Hybrid Therapy and Bismuth Quadruple Therapy

Helicobacter Pylori Infection

Taiwan
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

Healthy Volunteers

United States
Fadoi Foundation, Italy

Completed

Comparison Between Levofloxacin and Prulifloxacin, in Internal Medicine Patients With Acute Exacerbation of COPD (FLOR)

COPD Exacerbation

Italy
Kaohsiung Veterans General Hospital.

Completed

Comparing the Efficacy of Hybrid, High-dose Dual and Bismuth Quadruple Therapies

Helicobacter Pylori Infection

Taiwan
Suzhou Connect Biopharmaceuticals, Ltd.

Completed

A Study to Evaluate the Pharmacokinetics Similarity of CBP-201 in Healthy Adult Chinese Subjects

Healthy Adult Subjects

China
Emory University
National Cancer Institute (NCI)

Completed

Calcium/Vitamin D, Biomarkers & Colon Polyp Prevention (PPS4B)

Colorectal Adenomatous Polyps

United States
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

Healthy

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)

Healthy
IRCCS San Raffaele
Menarini International Operations Luxembourg SA

Completed

Effects of Ranolazine on Coronary Microvascular Dysfunction in Patients With Hypertrophic Cardiomyopathy

HCM - Hypertrophic Non-Obstructive Cardiomyopathy

Italy
Canadian Heart Research Centre
GlaxoSmithKline

Completed

Avandia™ + Amaryl™ or Avandamet™ Compared With Metformin (AVALANCHE™ Study) (AVALANCHE)

Type 2 Diabetes Mellitus

Canada
Cross Research S.A.
Zambon SpA

Completed

Safinamide Steady State Interaction With Rosuvastatin

Healthy

Switzerland
Grifols Therapeutics LLC

Completed

A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft Occlusion (PRIORITY)

Arterial Occlusive Diseases

United States
Seoul National University Hospital

Completed

A Clinical Trial for Analysis of Intestinal Microbiome Affecting PK, PD, and Safety of Metformin

Human Microbiome

Korea, Republic of
GlaxoSmithKline

Completed

A Study to Assess the Safety and Interaction Between Casopitant and Ketoconazole When Taken By Healthy Adults

Nausea and Vomiting, Chemotherapy-Induced

United States
Novartis Pharmaceuticals

Completed

Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential Hypertension (ALLAY)

Hypertension | Overweight | Left Ventricular Hypertrophy

United States, Finland, Sweden, Germany, Italy, Spain, Argentina, Colombia, Russian Federation
Pfizer
Halozyme Therapeutics

Terminated

Pharmacokinetic and Pharmacodynamic Study of Bococizumab Alone and When Combined With Recombinant Human Hyaluronidase

Healthy | Hypercholesterolemia

Belgium
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Phase I Study of Direct Coagulation Factor Xa Inhibitor SYHA136 Tablets in Chinese Healthy Volunteers

Venous Thrombosis
Fundacion Oncosur

Completed

Neurotoxicity Characterization Study of Nab-paclitaxel Versus Conventional Paclitaxel in Metastatic Breast Cancer (neurabrax)

Breast Cancer

Spain
The University of Texas Health Science Center,...
National Center for Advancing Translational Sciences (NCATS)

Completed

Stroke Telemedicine Outpatient Prevention Program for Blood Pressure Reduction (STOP-Stroke)

Blood Pressure | Telemedicine | Psychosocial Impairment | Stroke Prevention

United States
Zhejiang Haichang Biotech Co., Ltd.

Not yet recruiting

Phase 2 Study of WGI-0301 in Combination With Sorafenib for Advanced HCC

Advanced Hepatocellular Carcinoma (HCC)

3

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