Search clinical trials for: Placebo (methotrexate)

Total 54890 results

Icahn School of Medicine at Mount Sinai

Terminated

Doxycycline in Treating Patients With Chronic Rhinosinusitis With Nasal Polyps

Polyp of Nasal Sinus

United States
Sutter Health

Completed

Nuedexta for the Treatment of Adults With Autism (Nuedexta)

Autism

United States
Par Pharmaceutical, Inc.
Novum Pharmaceutical Research Services

Terminated

Bioequivalence of Two Ciprofloxacin 0.3%/Dexamethasone 0.1% Sterile Otic Suspensions in Otitis Media in Children With Tympanostomy Tubes

Otitis Media in Patients With Tympanostomy Tubes

United States
Pearl Therapeutics, Inc.

Completed

Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2)

Chronic Obstructive Pulmonary Disease (COPD)

United States
The First Affiliated Hospital with Nanjing Medical...
National Natural Science Foundation of China

Unknown

Different Platelet Activities Between Intracoronary and Peripheral Blood in Coronary Artery Disease Patients (DPABIAP)

Coronary Artery Disease

China
Merck Sharp & Dohme LLC

Completed

Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)

Pain, Postoperative Arthroscopy
Herbert Lindsley, MD

Completed

Effect of Intraarticular Steroids on Bone Turnover in Osteoarthritis

Osteoarthritis

United States
Orexigen Therapeutics, Inc

Completed

Study to Evaluate the Effect of Naltrexone and Bupropion Extended-Release Combination on Cardiac Repolarization in Healthy Participants

Heart Repolarization

United States
Vanderbilt University

Completed

Comparative Effects of Aspirin and NHP-544C

Healthy

United States
Astellas Pharma Europe B.V.

Completed

First-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of Pharmacology

Healthy Volunteers

United Kingdom, Germany
e-Therapeutics PLC

Completed

Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects

Cancer | Pharmacokinetics | Tolerability | Safety

United Kingdom
Ullevaal University Hospital
University of Oslo

Completed

Analgesic Effect of Paracetamol, Paracetamol + Codeine, Ibuprofen and Their Combination

Pain, Postoperative

Norway
Planned Parenthood League of Massachusetts
Society of Family Planning

Completed

Cervical Preparation Before Dilation and Evacuation

Abortion, Induced

United States
Bristol-Myers Squibb

Completed

Ph II Trial of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Second-line Treatment of Metastatic Colorectal Cancer

Colorectal Cancer (CRC)

United States, Argentina, Italy
Vanderbilt University
Forest Laboratories

Completed

Nebivolol in the Supine Hypertension of Autonomic Failure

Hypertension | Multiple System Atrophy | Pure Autonomic Failure

United States
GlaxoSmithKline

Withdrawn

A Study of IV Casopitant for the Prevention of Nausea and Vomiting Caused By Cisplatin-Based Highly Emetogenic Chemotherapy

Cancer | Solid Tumor Cancer | Chemotherapy-Induced Nausea and Vomiting | Nausea and Vomiting

United States, Canada
Boehringer Ingelheim

Completed

Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin in Healthy Male and Female Volunteers

Healthy
Zalicus

Completed

Multicenter Study to Evaluate CRx-102 vs. Each of Its Components to Treat Active Rheumatoid Arthritis (MARS-1)

Rheumatoid Arthritis

United States, Poland, Argentina, Romania, Serbia, Canada, Estonia, Russian Federation, Lithuania, South Africa, Hungary, Mexico
Yale University
VA Connecticut Healthcare System

Completed

The Effect of Cycloserine on Smoking Behavior in Nicotine Dependent Smokers

Smoking

United States
Felipe Melo Cruz

Completed

Vitamin E for Oxaliplatin-induced Peripheral Neuropathy Prophylaxis

Peripheral Neuropathy

Brazil
AGUNCO Obstetrics and Gynecology Centre

Completed

Clinical, Metabolic and Endocrine Effects of the Treatment With Drospirenone and Ethinyl Estradiol Alone or in Combination With Myo-inositol in Young Women With Polycystic Ovary Syndrome (PCOS) and Insulin Resistance

Polycystic Ovary Syndrome | PCOS

Italy
Novartis

Completed

To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies

Type 2 Diabetes Mellitus | Impaired Glucose Tolerance

United States, Canada, Finland, Australia, Germany, India, Italy
Hospital de Clinicas de Porto Alegre

Unknown

Efficacy and Safety Assessment of an Anti-Cold Preparation in the Symptomatic Treatment of Common Cold and Flu-Like Syndrome

Common Cold | Flu-like Syndrome

Brazil
AstraZeneca
Parexel

Not yet recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Sanofi Pasteur, a Sanofi Company

Recruiting

Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers (CORAL)

RSV Immunization

United States
S.LAB (SOLOWAYS)
NMSI DENTMASTER

Not yet recruiting

A Combination of Ibuprofen With Curcumin Covered With Liquorice Root Supplementation in the Management of Postoperative Dental Pain in Adults (ICLID)

Dental Pain

Russian Federation
National Cancer Institute, Egypt

Recruiting

Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain

Post-mastectomy Pain Syndrome

Egypt
Cingulate Therapeutics

Recruiting

Phase 3 Efficacy and Safety Laboratory Classroom Study in Pediatrics (6-12) With ADHD Using CTx-1301

ADHD | Attention Deficit Hyperactivity Disorder | Attention Deficit Disorder With Hyperactivity | ADHD - Combined Type | Attention Deficit Hyperactivity Disorder Combined | Attention Deficit Hyper Activity | Attention-deficit Hyperactivity

United States
Cairo University

Not yet recruiting

How to Reduce Pain in Patients Undergoing Office Hysteroscopy.

Pain
University Hospital, Basel, Switzerland

Recruiting

Acute Effects of 2C-B Compared With MDMA and Psilocybin in Healthy Subjects (2C-B)

Healthy

Switzerland
Guangdong Association of Clinical Trials
Chinese Thoracic Oncology Group

Recruiting

Phase II Umbrella Study Directed by Next Generation Sequencing (TRUMP)

Carcinoma, Non-Small-Cell Lung

China
University of Chicago
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Chicago Social Drinking Project (CSDP)

Alcoholism

United States
Benha University

Completed

Buccal Midazolam Versus Intranasal Dexmedetomidine Plus Oral Chloral Hydrate in Inguinal Hernia Repair

Inguinal Hernia Repair

Egypt
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

Poland, Romania, Ukraine, Chile, Canada, United States, Argentina, China, Czechia, Estonia, France, Germany, Hungary, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Mexico, Norway, Peru, Russian Federation, Spain, Thailand, Turkey, United...
Acerta Pharma BV
AstraZeneca

Active, not recruiting

A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312) (ESCALADE)

Diffuse Large B-Cell Lymphoma

United States, France, Italy, Spain, Canada, Taiwan, Germany, Korea, Republic of, Brazil, Japan, Russian Federation, Poland, China, Israel, Belgium, Australia, Austria, Czechia, Portugal, Mexico, Turkey, India, Ukraine
University of Wisconsin, Madison

Completed

The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope

Syncope, Vasovagal

United States
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

CYP3A4 Activity and Mineral Homeostasis

Vitamin D and Calcium Homeostasis

United States
University of Arkansas
National Institute on Drug Abuse (NIDA)

Completed

Improving Treatment Outcomes for Prescription Opioid Dependence (GBN)

Drug Dependence

United States
University of Nottingham
University of Oxford; Nottingham University Hospitals NHS Trust; University of... and other collaborators

Completed

Helicobacter Eradication Aspirin Trial (HEAT)

Bacterial Infection Due to Helicobacter Pylori (H. Pylori) | Gastrointestinal Ulcer Haemorrhage

United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study of Laquinimod in Participants With Systemic Lupus Erythematosus (SLE) Active Lupus Nephritis

Lupus Nephritis

United States, Canada, France, Russian Federation, United Kingdom
Organon and Co

Terminated

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in Women With Primary Dysmenorrhea (With Optional Extension) (MK-8342B-059)

Moderate to Severe Primary Dysmenorrhea
Gynecologic Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Endometrial Adenocarcinoma | Stage III Uterine Corpus Cancer AJCC v7 | Stage IIIA Uterine Corpus Cancer AJCC v7 | Stage IIIB Uterine Corpus Cancer... and other conditions

United States
Vejle Hospital

Terminated

Tocotrienol as a Nutritional Supplement in Patients With Advanced Lung Cancer (Toco-Pulm)

Lung Cancer

Denmark
Cairo University

Unknown

Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression

Symptomatic Irreversible Pulpitis
Glenmark Pharmaceuticals Ltd. India

Completed

To Study GSP 301 in Patients With Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

United States
ORA, Inc.

Completed

Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model

Allergic Conjunctivitis

United States
H. Lundbeck A/S
Takeda

Completed

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD)

Depressive Disorder, Major

United States, Bulgaria, Canada, Colombia, Estonia, France, Germany, Hungary, Italy, Korea, Republic of, Latvia, Mexico, Poland, Russian Federation, Serbia, South Africa, Spain, Ukraine, United Kingdom
Glenmark Pharmaceuticals Ltd. India

Completed

To Study Generic Calcipotriene and Betamethasone Dipropionate Topical Foam, 0.005%/0.064%, in the Treatment of Psoriasis Vulgaris (Plaque Psoriasis).

Psoriasis Vulgaris

United States
Mahmoud Samy Abdallah

Completed

Role of Pentoxifylline as an Adjuvant Therapy for Adult Patients With Major Depressive Disorder

Major Depressive Disorder
Peking University People's Hospital

Unknown

Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome (CTRIPS)

Sjogren's Syndrome

China

Search clinical trials for: Placebo (methotrexate)

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