Search clinical trials for: Placebo to match MMV390048 80 mg

Total 438 results

Organon and Co

Completed

The Single Dose Pharmacokinetics of Two and Proof of Efficacy of One New Etoricoxib Gel Formulation in Participants With Osteoarthritis (MK-0663-168)

Osteoarthritis Pain
Hamilton Health Sciences Corporation
Population Health Research Institute

Terminated

Beta Blockers and Angiotensin Receptor Blockers in Bicuspid Aortic Valve Disease Aortopathy (BAV Study) (BAV)

Cardiac Disease

Canada
Purdue Pharma LP

Completed

Buprenorphine Accumulation and Description of Its Metabolites During Co-Medication of Buprenorphine Transdermal System (BTDS) and Ketoconazole

Healthy

United States
Jiangsu Hansoh Pharmaceutical Co., Ltd.
Nanjing Medical University

Unknown

Phase Ⅲ Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg-positive Chronic Hepatitis B (PEG-Tα1)

Hepatitis B, Chronic

China
Murdoch Childrens Research Institute

Suspended

Can Vitamin D Treatment Help Treat Moderate to Severe Atopic Dermatitis in Young Children? The D-Vex Pilot Study (D-Vex)

Atopic Dermatitis

Australia
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Lipid Biomarkers for Diabetic Heart Disease

Diabetes Complications | Type II Diabetes Mellitus

United States
Merck Sharp & Dohme LLC

Terminated

A Study of MK-6913 for the Treatment of Hot Flashes in Postmenopausal Women (6913-004)

Women | Moderate to Severe Vasomotor Symptoms in Postmenopausal
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Venlafaxine ER Phase 3 Study for Major Depressive Disorder (MDD)

Major Depressive Disorder

Japan
Biolab Sanus Farmaceutica

Withdrawn

Pharmacokinetics, Pharmacodinamic and Safety of Testosterone Gel 1%

Post-menopausal Period
Organon and Co

Completed

Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-0663-145 AM1)

Dysmenorrhea
Colotech A/S

Terminated

Chemoprevention of Colorectal Adenomas

Adenomatous Polyps

United States, Russian Federation
GlaxoSmithKline

Completed

Emotional Processing in Healthy Volunteers in the Presence of an Investigational Anxiolytic

Depressive Disorder and Anxiety Disorders

United Kingdom
Assistance Publique - Hôpitaux de Paris

Recruiting

Efficacy of 24 Month of Bezafibrate in Primary Sclerosing Cholangitis With Persistent Cholestasis Despite Ursodeoxycholic Acid Therapy (BEZASCLER)

Primary Sclerosing Cholangitis | Cholestasis

France
University of Michigan

Completed

Predictors of Antidepressant Response

Depression

United States
Shahid Beheshti University of Medical Sciences

Unknown

Prevention of Venous Obstruction After Implantation of Cardiac Pacemaker and Defibrillator

Venous Occlusion | Complication of Cardiac Defibrillator | Disorder of Cardiac Pacemaker System

Iran, Islamic Republic of
Merck Sharp & Dohme LLC
Pfizer

Completed

Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)

Type 2 Diabetes Mellitus
Memorial Sloan Kettering Cancer Center

Withdrawn

Transdermal Methylphenidate for Cancer-Related Fatigue

Head and Neck Cancer
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Efficacy of MK-7655 (Relebactam) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for Treating Complicated Urinary Tract Infection (cUTI) (MK-7655-003)

Urinary Tract Infections | Pyelonephritis
Oslo University Hospital
University of Oslo; South-Eastern Norway Regional Health Authority

Completed

Lowering Uric Acid in Live Kidney Donors (AL-DON)

Renal Transplant Donor of Left Kidney | Renal Transplant Donor of Right Kidney

Norway
Research Institute for Complex Problems of Cardiovascular...

Completed

Left Atrial Mechanical Function Improvement After Atrial Fibrillation Catheter Ablation

Atrial Fibrillation
Purdue Pharma LP

Completed

Efficacy and Safety of Hydrocodone Bitartrate (HYD) in Subjects With Moderate to Severe Chronic Low Back Pain

Chronic Low Back Pain

United States
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

Pain | Knee Osteoarthritis

Austria, Croatia, Germany, Hungary, Italy, Latvia, Netherlands, Poland, Portugal, Romania, Slovakia, Spain, United Kingdom
Rush University Medical Center

Completed

Aprepitant- and Olanzapine- Containing Anti-emetic Regimens With High Dose Melphalan

Nausea | Vomiting

United States
Aswan University Hospital

Unknown

Aspirin for Prevention of Preeclampsia

Preeclampsia

Egypt
Gilead Sciences

Completed

Study Evaluating the Efficacy and Safety of Idelalisib in Combination With Bendamustine and Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL) (Tugela ) (Tugela)

Chronic Lymphocytic Leukemia

United States, Hungary, Belgium, United Kingdom, France, Australia, Turkey, Croatia, Italy, Poland, Canada, Greece, Czechia, Ireland, Russian Federation, Spain, Portugal, Romania
İlke Karabıyık

Completed

Nonpharmacological Management of Postoperative Pain in Children

Orthopedic Disorder | Post Operative Pain

Turkey
Emergo Therapeutics, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Norketotifen in Healthy Subjects

Healthy Subjects

United States
Stanford University

Completed

Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids

Hyperalgesia

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Doravirine/Islatravir (DOR/ISL 100 mg/0.75 mg) to Evaluate the Antiretroviral Activity, Safety, and Tolerability in Treatment-Naïve Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-020)

HIV-1 Infection

United States, Argentina, Canada, Chile, Colombia, France, Germany, Israel, Italy, Japan, South Africa, Spain, Taiwan
Boehringer Ingelheim

Completed

Efficacy and Safety of BI 1356 in Combination With Metformin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Bulgaria, Denmark, France, Germany, Hong Kong, Hungary, India, Ireland, Italy, Netherlands, Norway, Poland, South Africa, Sweden, United Kingdom
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study To Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).

Type 2 Diabetes Mellitus
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease (ENDO)

Sickle Cell Disease | Sickle Cell Nephropathy

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study of Evaluating the Efficacy and Safety of SHR4640 in Subjects With Gout

Gout

China
Idorsia Pharmaceuticals Ltd.

Completed

To Study the Effect of Aprocitentan on the Electrical Activity of the Heart in Healthy Men and Women

Healthy Subjects

Germany
Herlev Hospital

Completed

The Laparotomy Study

Gastrointestinal Cancer

Denmark
Tesaro, Inc.

Completed

Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy (HEC)

Chemotherapy-induced Nausea and Vomiting

United States
Gilead Sciences

Terminated

Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma

Colorectal Cancer

Spain, United States, Germany, Italy, Russian Federation, Poland, France
Tesaro, Inc.

Completed

Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy

Chemotherapy-induced Nausea and Vomiting

United States
Tesaro, Inc.

Completed

Ph 3 Safety/Efficacy Study of Rolapitant for Prevention of CINV in Subjects Receiving Moderately Emetogenic Chemotherapy

Chemotherapy-induced Nausea and Vomiting

United States
MedImmune LLC
Thrombolysis in Myocardial Infarction (TIMI) Study Group

Completed

A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction (REAL-TIMI 63B)

ST Elevation Myocardial Infarction

Netherlands, United Kingdom, Brazil, Spain, Slovakia, Israel, Czechia, Hungary, Poland, Russian Federation
Genentech, Inc.

Completed

A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As First-Line Therapy for Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
Vanderbilt University Medical Center

Withdrawn

Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2

Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure NYHA Class I

United States
Merck Sharp & Dohme LLC

Terminated

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial to Evaluate the Safety, Tolerability, and Efficacy of MK-8457 in Participants With Rheumatoid Arthritis (MK-8457-010)

Rheumatoid Arthritis
Wockhardt

Completed

Evaluate the Effect of WCK 5222 on the QT/QTc Interval in Healthy Volunteers

QT/QTc Interval in Healthy Volunteers

United States
Hospital Universitario San Ignacio
Pontificia Universidad Javeriana; Hospital Universitario Nacional de Colombia; Hospital de la Samaritana, Sede Bogotá y Sede Zipaquirá and other collaborators

Unknown

Daily Regimen of Tenofovir/Emtricitabine as Prevention for COVID-19 in Health Care Personnel in Colombia

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2
Tris Pharma, Inc.
Forest Laboratories

Completed

Evaluation of the Effects of Multiple Doses of Cebranopadol on the Electrical Activity of the Heart in Healthy Subjects

Prolonged QTc Interval | Pharmacokinetic

United States
Jong Woo Chung
Asan Medical Center; SK Chemicals Co., Ltd.

Terminated

Effect of Renexin Tablet in Patients With Recurrent Vestibulopathy (REREV)

Recurrent Vestibulopathy

Korea, Republic of
Sunovion

Completed

A Comparison of Study Drug With Placebo and Haloperidol in Patients With Schizophrenia

Schizophrenia

United States
Institut Curie
Hoffmann-La Roche; Ministry of Health, France; Amgen; Pierre Fabre Laboratories

Active, not recruiting

Cranial Radiotherapy or Intensive Chemotherapy With Hematopoietic Stem Cell Rescue for Primary Central Nervous System Lymphoma in Young Patients (PRECIS)

Primary Central Nervous System Lymphoma

France
Uniformed Services University of the Health Sciences
U.S. Army Medical Research and Development Command

Completed

Safety Study of Riluzole to Treat Post-traumatic Stress Disorder (PTSD)

PTSD

United States

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