Search clinical trials for: Placebo to match hydroxyurea

Total 1425 results

Brooke Army Medical Center
Hoffmann-La Roche; The Geneva Foundation

Completed

Study for the Treatment of Significant Steatosis With Xenical Followed by Treatment of Hepatitis C With Pegasys/Copegus (HCVNASH)

Hepatitis C | Fatty Liver

United States
Recep Tayyip Erdogan University

Completed

Comparison of Metoprolol and Tramadol With Remifentanil in Endoscopic Sinus Surgery

Nasal Polyps

Turkey
Novartis Pharmaceuticals

Completed

Efficacy, Safety, and Pharmacokinetics of QAW039

Persistent Asthma

United States, Germany, Korea, Republic of, Romania, Belgium
Boehringer Ingelheim

Completed

Ibuprofen/Caffeine Lower Back or Neck Pain Study

Back Pain | Neck Pain

Russian Federation, Germany
Astellas Pharma Inc

Completed

Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)

Coronary Artery Disease (CAD)

United States
Eastern Hepatobiliary Surgery Hospital

Completed

Preoperative Pain Control in Liver Surgery Patients

Pain, Postoperative | Hepatocellular Carcinoma

China
Legacy Health System

Completed

Preoperative Pain Control in Gastric Bypass Surgery Patients

Post-operative Pain

United States
Walid HABRE

Terminated

Intranasal Dexmedetomidine for Procedural Pain Management in Elderly Adults in Palliative Care (INDEX)

Analgesia | Sedation | Anxiolysis

Switzerland
Assembly Biosciences

Completed

A Study in Healthy Volunteers and Patients With Chronic Hepatitis B

Chronic Hepatitis B

New Zealand
Cairo University

Completed

Dexmedetomidine in Different Dose Levels as Adjuvant to Bupivacaine-induced Ultrasound-guided Femoral Nerve Block.

Dexmedetomidine | Arthroscopic Knee Surgery | Femoral Nerve Block

Egypt
University of Arizona

Unknown

Evaluation of the Metformin Effect on Methylglyoxal in Patients With Type 2 Diabetes (MET)

Type 2 Diabetes Mellitus
Senju USA, Inc.

Completed

Evaluation of the Safety and Efficacy of Ketotifen 4.0% Patch as Compared to Placebo Patch, Olopatadine 0.2% Ophthalmic Solution, and Artificial Tears in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Athens General Children's Hospital "Pan. & Aglaia...

Completed

Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia

Blood Pressure | Emergence Delirium | Heart Rate | Postoperative Analgesia | Extubation Time

Greece
Kufa University

Completed

Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis

Iraq
Novartis Pharmaceuticals

Withdrawn

Study of Efficacy and Safety of NVA237 in Patients With Poorly Controlled Asthma

Asthma
Novartis Pharmaceuticals

Completed

Efficacy and Safety of NVA237 in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Germany, Hungary, Belgium, Poland, Spain, Netherlands
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Efficacy of MK-7655 (Relebactam) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for Treating Complicated Urinary Tract Infection (cUTI) (MK-7655-003)

Urinary Tract Infections | Pyelonephritis
Merck Sharp & Dohme LLC

Completed

Study of Biomarkers of Airway Inflammation (0000-128)

Airway Inflammation
Merck Sharp & Dohme LLC

Active, not recruiting

Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826)

Cervical Cancer

Japan, United States, Argentina, Australia, Canada, Chile, Colombia, France, Germany, Israel, Italy, Korea, Republic of, Mexico, Peru, Russian Federation, Spain, Taiwan, Turkey, Ukraine
Craig Hospital
Allergan; The Craig H. Neilsen Foundation

Completed

Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.

Pain | Spinal Cord Injury

United States
US Department of Veterans Affairs

Completed

Nicotine Patch Pretreatment for Smoking Cessation in PTSD

Tobacco Use Disorder | Stress Disorders, Posttraumatic

United States
Pfizer
GlaxoSmithKline

Completed

Study Evaluating The Safety And Efficacy Of Varenicline and Bupropion For Smoking Cessation In Subjects With And Without A History Of Psychiatric Disorders (EAGLES)

Smoking Cessation

United States, Spain, Germany, Canada, South Africa, Finland, Denmark, Australia, Brazil, Bulgaria, Chile, Mexico, New Zealand, Russian Federation, Slovakia, Argentina
Organon and Co

Completed

The Single Dose Pharmacokinetics of Two and Proof of Efficacy of One New Etoricoxib Gel Formulation in Participants With Osteoarthritis (MK-0663-168)

Osteoarthritis Pain
Orexigen Therapeutics, Inc

Completed

A Study Using Functional Magnetic Resonance Imaging (fMRI) to Assess the Effects of Naltrexone SR/ Bupropion SR Therapy in Overweight or Obese Subjects

Obesity

United States
Organon and Co
Novartis

Completed

Effects of Mometasone Furoate/Formoterol Combination Versus Formoterol and Mometasone Furoate Alone in COPD (Study P04229AM4)(COMPLETED)

Chronic Obstructive Pulmonary Disease (COPD)
Claire Daniels

Unknown

EoE RCT Fluticasone and Omeprazole vs Fluticasone Alone

Eosinophilic Esophagitis

United States
Merck Sharp & Dohme LLC

Completed

Aprepitant/MK0869 for Prevention of Chemotherapy Induced Nausea and Vomiting Associated With Cisplatin (0869-169)(COMPLETED)

Chemotherapy-induced Nausea and Vomiting (CINV)
University Hospital, Basel, Switzerland

Completed

Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study

Healthy | Substance-related Disorder | Mood Disorder

Switzerland
Pontificia Universidade Catolica de Sao Paulo

Completed

Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration

Fractures, Bone | Pruritus | Satisfaction, Personal | Nausea and Vomiting, Postoperative | Morphine Adverse Reaction

Brazil
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Completed

Dietary Supplement of Curcumin in Subjects With Active Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta 1a (CONTAIN)

Multiple Sclerosis

Italy
Mutual Pharmaceutical Company, Inc.

Completed

A Pharmacokinetic Study of Colchicine With an Oral Contraceptive

Pharmacokinetics

United States
Nanfang Hospital, Southern Medical University

Recruiting

Rapid Improvement of Depression of Fluoxetine Combined With ATP

Depression

China
MediciNova
Wake Forest University Health Sciences

Completed

Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS) (IBU-ALS-1201)

Amyotrophic Lateral Sclerosis

United States
Amgen

Terminated

Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid Arthritis

Juvenile Rheumatoid Arthritis
University of Southern California

Terminated

Romiplostim in Treating Hepatitis C-Infected Patients With Thrombocytopenia

Thrombocytopenia | Hepatitis C Infection

United States
University of Texas at Austin

Completed

Enhancing Panic and Smoking Reduction Treatment With D-Cycloserine (DCS/PSRT)

Panic Attack | Nicotine Addiction

United States
MEDRx USA, Inc.

Completed

Etodolac-Lidocaine Patch in the Treatment of Acute Low Back Pain

Low Back Pain

United States
University of Arizona

Completed

IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery

Lower Limb Injury

United States
Pfizer

Completed

Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders. (CATS)

Smoking Cessation

United States, Spain, Germany, Canada, South Africa, Finland, Denmark, Australia, Argentina, Brazil, Bulgaria, Chile, Mexico, New Zealand, Russian Federation, Slovakia
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)

Urinary Bladder Neoplasms

United States, Australia, Czechia, Estonia, France, Guatemala, Hungary, Israel, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, Poland, Portugal, Puerto Rico, Romania, Spain, Taiwan, Turkey, Ukraine, United Kingdom, Denmark, ... and more
Tiva Group

Completed

Morphine Consumption in the Obese Patients

Anesthesia Morbidity | Obesity, Morbid | Opioid Use | Post Operative Pain | Pharmacological Action

Spain
Tatyasaheb Kore Dental College

Completed

Analgesic Efficacy of Arnica Montana in Comparison With Diclofenac Sodium Following a Periodontal Surgical Procedure

Crown Lengthening Procedure With Ostectomy

India
Sunovion

Completed

Lurasidone Low-Dose - High-Dose Study Study

Schizophrenia

United States, Ukraine, Romania, Slovakia, Colombia, Russian Federation
Purdue Pharma LP

Completed

The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) at Doses up to 80 Micrograms/Hour (mcg/hr) and Naltrexone on Electrocardiogram (ECG) Intervals in Healthy Volunteers

ECG Effects

United States
AO GENERIUM

Withdrawn

Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema

Hereditary Angioedema

Russian Federation
Boehringer Ingelheim

Completed

Effectiveness of Two Different Doses of BI 1026706 on the Overall Peak-to-Peak (PtP) N2/P2-component Amplitude of Laser (Somatosensory, Radiant-heat) Evoked Potentials (LEP) in UVB(Ultraviolet)-Irradiated Skin in Healthy Male Volunteers

Healthy

Germany
Novartis
Merck Sharp & Dohme LLC

Completed

Bronchodilatory Efficacy of a Single Dose QMF149 (Indacaterol Maleate/Mometasone Furoate) Via the Twisthaler® Device in Adult Patients With Asthma

Asthma

France, Germany
Creighton University
GlaxoSmithKline

Withdrawn

Adolescent and Adult Subjects With Asthma and Seasonal Allergic Rhinitis Receiving Advair Diskus or Placebo

Asthma | Seasonal Allergic Rhinitis

United States
Mark Ware

Terminated

Genetic Variants Associated With Low Back Pain and Their Response to Treatment With Duloxetine or Propranolol

Low Back Pain

Canada
Emory University

Completed

Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery (SITACABG NonDM)

Coronary Artery Disease

United States

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