Search clinical trials for: placebo to zoledronic acid

Total 5951 results

National Taiwan University Hospital

Recruiting

The Optimal Long Term Treatment Strategy of Anti-resorptive Medications---The Extension of Denosumab Sequential Therapy

Osteoporosis | Bone Mineral Density

Taiwan
Nantes University Hospital

Terminated

Bone Demineralization Lesions in the Injured Marrow: Efficacy and Tolerability of Administration Early and Repeated the Zoledronic Acid. Comparative Study, Prospective, Double-blind Controlled (DBMZol) (DBMZol)

Bone Demineralization Lesions in the Injured Marrow

France
Novartis Pharmaceuticals
University of Athens

Completed

Effect Of Zoledronic Acid On Circulating And Bone Marrow-Residing Prostate Cancer Cells In Patients With Clinically Localized Prostate Cancer

Prostate Cancer

Greece
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Single Dose of 5 mg Zoledronic Acid in Chinese Patients With Paget's Disease of Bone (PDB)

Paget's Disease of Bone

China
Novartis Pharmaceuticals

Completed

The Use of Zoledronic Acid in Men on Androgen Deprivation Therapy for Prostate Cancer With Preexisting Osteoporosis

Prostate Cancer

United States
Germans Trias i Pujol Hospital

Completed

Efficacy And Security Of Annual And Biennial Zoledronic Acid For Osteoporosis Treatment In An HIV-Infected Patients' Cohort

HIV Infections

Spain
Novartis

Withdrawn

Zoledronic Acid Treatment of Spontaneous Osteonecrosis of the Knee

Osteonecrosis

Australia
Fudan University

Unknown

The Effect of Zoledronic Acid to Bone Fusion and Bone Metabolism of Patients With Lumbar Degenerative Disease After Lumbar Interbody Fusion

Bone Mineral Density | Bone Turnover Markers | Image Changes of Lumbar Fusion

China
The Cleveland Clinic
Novartis

Completed

Safety and Efficacy Study of Concomitant Radiotherapy and Zoledronic Acid for Bone Metastases Palliation

Breast Cancer | Lung Cancer | Prostate Cancer | Bone Metastases
Sun Yat-sen University

Recruiting

HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC

Hepatocellular Carcinoma

China
Daping Hospital and the Research Institute of Surgery...

Unknown

Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Bone Metastasis
University Health Network, Toronto
Canadian Breast Cancer Foundation

Completed

Suppression of Bone Turnover Following Treatment With Zoledronic Acid in Patients With Metastatic Breast Cancer: Duration of Effect (SuBDuE)

Metastatic Breast Cancer With Bone Involvement

Canada
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Zoledronic Acid in Patients With Breast Cancer With Metastatic Bone Lesions

Breast Cancer With Bone Metastasis

Italy
Centre Leon Berard

Terminated

Efficacy and Safety of Systemic Treatments of Bone Metastases From Kidney Cancer in Patients Treated With Targeted Therapies (MOSCAR)

Metastatic Renal Cell Carcinoma

France
PETHEMA Foundation
Novartis; Dynamic Solutions

Completed

Zoledronic Acid in Patients With Multiple Myeloma and Asymptomatic Biochemical Relapse (AZABACHE)

Multiple Myeloma

Spain
Severance Hospital

Completed

Efficacy of Radiotherapy in Combination With Zoledronic Acid in Bone Metastasis Patients With Gastrointestinal Tumors

Gastrointestinal Cancer | Bone Metastasis

Korea, Republic of
HealthPartners Institute
Novartis Pharmaceuticals

Completed

Effects of Zometa and Physical Activity on Bone Density in Women Receiving Chemotherapy for Breast Cancer

Breast Cancer

United States
Korean Breast Cancer Study Group

Unknown

Evaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer Patients

Metastatic Breast Cancer

Korea, Republic of
Tang-Du Hospital

Unknown

Preventive Effects of Zoledronic Acid on Bone Metastasis in Patients With Stage IIIB and IV Lung Cancer

Lung Cancer

China
German Breast Group
Novartis Pharmaceuticals; Austrian Breast & Colorectal Cancer Study Group

Completed

Postoperative Use of Zoledronic Acid in Breast Cancer Patients After Neoadjuvant Chemotherapy (NATAN)

Breast Cancer

Germany, Austria
Washington University School of Medicine

Terminated

Perioperative Treatment With Zoledronic Acid in Patients With Resectable Pancreas Cancer

Adenocarcinoma

United States
Wirral University Teaching Hospital NHS Trust
Novartis

Completed

Frequency of Zoledronic Acid to Prevent Further Bone Loss in Osteoporotic Patients Requiring Androgen Deprivation Therapy for Prostate Cancer

Osteoporosis

United Kingdom
Daewoong Pharmaceutical Co. LTD.

Recruiting

Study to Investigate the Efficacy and Safety After Administration of Daewoong Zoledronic Acid for the Purpose of Treatment or Prevention of Osteoporosis

Osteoporosis

Korea, Republic of
Bayside Health
Novartis

Completed

Comparison of Pamidronate With Zoledronic Acid for Transplant Related Bone Loss Prevention

Osteopenia | Complications of Heart-lung Transplant | Other Complications of Lung Transplant
Soroka University Medical Center
Tel-Aviv Sourasky Medical Center

Completed

Effectiveness of Zoledronic Acid in the Prevention of Osteoporosis in Early Breast Cancer Patients Receiving Letrozole

Breast Cancer

Israel
Hoffmann-La Roche

Terminated

A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease

Pain | Neoplasm Metastasis | Bone Neoplasm

United States, Mexico, Germany, Russian Federation, Italy, Hungary, Belgium, Chile, France, Argentina, Australia, Switzerland, Guatemala, Puerto Rico, Poland, Panama, United Kingdom, Canada
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.

Breast Cancer
Memorial Sloan Kettering Cancer Center

Completed

Investigation of Changes in Bone Scan Imaging Before and After Intravenous Bisphosphonate Therapy for Osseous Metastases From Breast Cancer

Osseous Lesions From Metastatic Breast Cancer

United States
Seoul National University Bundang Hospital
Novartis Korea Ltd.

Completed

Efficacy of Zoledronic Acid in Preventing Collapse of the Osteonecrotic Femoral Head (EZAPCOFH)

Avascular Necrosis of Femoral Head

Korea, Republic of
Novartis

Completed

Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

Pain | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Hypercalcemia of Malignancy

United States
National Taiwan University Hospital

Recruiting

The Optimal Sequential Therapy After Long Term Denosumab Treatment

Osteoporosis

Taiwan
James J. Peters Veterans Affairs Medical Center
Kessler Institute for Rehabilitation

Completed

Zoledronic Acid Administration in Acute Spinal Cord Injury

Disuse Osteoporosis

United States
University of Sao Paulo General Hospital

Completed

Zoledronic Acid to Prevent Bone Loss After Kidney Transplantation

Renal Osteodystrophy

Brazil
Sun Yat-sen University
Novartis

Completed

To Evaluate the Efficacy of ZOMETA® in Treatment of Bone Metastases in Patients With Stage IV Nasopharyngeal Cancer

Nasopharyngeal Cancer

China
The University of Hong Kong
Prince of Wales Hospital, Shatin, Hong Kong; Queen Mary Hospital, Hong Kong; United... and other collaborators

Recruiting

The Effect of Zoledronate on the Prevention of Pneumonia in Hip Fracture Patients (Zoo-P)

Pneumonia | Hip Fractures

Hong Kong
Antonio Lazzari
Massachusetts General Hospital; United States Department of Defense; Spaulding... and other collaborators

Terminated

FES-Rowing Versus Zoledronic Acid to Improve Bone Health in Spinal Cord Injury (SCI)

Osteoporosis

United States
Assiut University

Recruiting

Delayed Versus Immediate Use Of Zoledronic Acid For Postmenopausal Patients With Early Breast Cancer Who Are Using Adjuvant Letrozole

Use of Zoledronic Acid in Breast Cancer

Egypt
University of Leeds
University of Sheffield

Terminated

Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone

Pain | Breast Cancer | Metastatic Cancer | Musculoskeletal Complications | Hypercalcemia of Malignancy

United Kingdom
Aristotle University Of Thessaloniki
251 Hellenic Air Force & VA General Hospital; 424 General Military Hospital

Completed

Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin of Postmenopausal Women With Low Bone Mass (DenoZol)

Postmenopausal Osteoporosis

Greece
Merrion Pharmaceuticals, LLC

Completed

Multi-Center Phase II Study to Compare MER-101 20mg Tablets to Intravenous Zometa 4mg in Male Bisphosphonate-Naive, Hormone Refractory Prostate Cancer Patients

Hormone-Refractory Prostate Cancer

United States, Estonia, Latvia
Cttq

Unknown

Generic Zoledronic Acid Versus Original Zoledronic Acid in Postmenopausal Osteoporotic Women

Osteoporosis, Postmenopausal
Novartis Pharmaceuticals

Completed

Zoledronic Acid in the Prevention of Bone Loss in Postmenopausal Women With Osteopenia, 45 Years of Age and Older

Osteopenia

United States
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Safety and Efficacy of Zoledronic Acid in the Prevention or Delaying of Bone Metastasis in Patients With Stage IIIA and IIIB Non-small Cell Lung Cancer (NSCLC)

Non-Small-Cell Lung Cancer

Greece, Taiwan, Germany, Belgium, Italy, Spain, United Kingdom, Korea, Republic of, Netherlands, China, Hungary, Poland, France, Thailand, Portugal
University of Sheffield

Unknown

Chemotherapy and/or Hormone Therapy With or Without Zoledronate in Treating Women With Stage II or Stage III Breast Cancer

Breast Cancer | Metastatic Cancer
Novartis Pharmaceuticals

Completed

A Multiple Myeloma Trial in Patients With Bone Metastases

Multiple Myeloma

United States
Ludwig-Maximilians - University of Munich
Eli Lilly and Company; Sanofi; Novartis; AstraZeneca; Chugai Pharma USA; Janssen Diagnostics...

Completed

Simultaneous Study of Gemcitabine-Docetaxel Combination Adjuvant Treatment, as Well as Extended Bisphosphonate and Surveillance-Trial

Breast Neoplasms

Germany
Shinshu University

Recruiting

Efficacy of Zoledronic Acid in Osteoporosis

Osteoporosis

Japan
Amgen

Completed

Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer

Bone Metastases
McGill University Health Centre/Research Institute...
Crohn's and Colitis Foundation

Completed

Zoledronate for Osteopenia in Pediatric Crohn's

Crohn's Disease | Osteoporosis | Osteopenia

Canada
Karolinska Institutet

Unknown

Bisphosphonates for the Treatment of Seropositive Musculoskeletal Complaints (PREVENT RA)

Seropositive Muskuloskeletal Complaints

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