Search clinical trials for: Placebo (semaglutide)

Total 54043 results

Novo Nordisk A/S

Active, not recruiting

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes (FOCUS)

Diabetes Mellitus, Type 2

Spain, United States, India, Czechia, Canada, Latvia, United Kingdom, Portugal, Serbia, Poland, Romania, Brazil, Russian Federation, Slovakia, Bulgaria, Mexico, Germany, Greece, Israel
Novo Nordisk A/S

Completed

A Research Study of How Semaglutide Works in People With Disease Affecting the Heart and/or Blood Vessels and Type 2 Diabetes

Diabetes Mellitus, Type 2

Denmark, Sweden, Austria
Novo Nordisk A/S

Active, not recruiting

A Research Study to Find Out How Semaglutide Works in the Kidneys Compared to Placebo, in People With Type 2 Diabetes and Chronic Kidney Disease (the REMODEL Trial) (REMODEL)

Diabetes Mellitus, Type 2 | Chronic Kidney Disease

Spain, United States, Italy, Denmark, Poland, South Africa, Canada, France
Novo Nordisk A/S

Completed

Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes (STEP HFpEF DM)

Heart Failure With Preserved Ejection Fraction (HFpEF) and Diabetes Mellitus, Type 2

United States, Spain, Hungary, United Kingdom, India, Netherlands, Germany, Japan, Canada, Czechia, Argentina, Austria, Israel, Italy, Poland, Sweden
Novo Nordisk A/S

Active, not recruiting

A Research Study to Compare a Medicine Called Semaglutide Against Placebo in People With Peripheral Arterial Disease and Type 2 Diabetes (STRIDE)

Diabetes Mellitus, Type 2 | Peripheral Arterial Disease

Spain, Taiwan, China, India, United States, Canada, Thailand, Austria, Malaysia, Germany, Poland, Japan, Czechia, Greece, Belgium, Denmark, Hungary, Latvia, Norway, Sweden
Fundación Instituto de Estudios de Ciencias de...

Not yet recruiting

Effect Of Semaglutide In Coronary Atheroma Plaque (SEPLA)

Atheroscleroses, Coronary
Novo Nordisk A/S

Completed

Trial Investigating the Absorption, Metabolism and Excretion After a Single Subcutaneous Dose of [3H]-Semaglutide in Healthy Male Subjects

Healthy | Diabetes

Netherlands
Novo Nordisk A/S

Completed

Investigating the Pharmacokinetics of Subcutaneous Injections With 1 mg/mL, 3 mg/mL, and 10 mg/mL Semaglutide Strengths and the Absolute Bioavailability of Semaglutide

Healthy | Diabetes

Germany
Novo Nordisk A/S

Completed

Effect of Food on the Pharmacokinetics of Oral Semaglutide in Healthy Subjects

Healthy | Diabetes

Germany
Novo Nordisk A/S

Completed

A Randomised, Single Centre, Double-blind, Two-period, Cross-over Trial in Healthy Subjects Investigating the Bioequivalence Between Subcutaneous Injections of Semaglutide Produced by Two Manufacturing Processes

Healthy | Diabetes

Germany
Novo Nordisk A/S

Active, not recruiting

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Spain, as Part of Local Clinical Practice (PIONEER REAL)

Diabetes Mellitus, Type 2

Spain
Novo Nordisk A/S

Enrolling by invitation

Post-Marketing Surveillance (Special Use-results Surveillance) on Long-term Use With Ozempic®

Diabetes Mellitus, Type 2

Japan
Novo Nordisk A/S

Completed

A Research Study Looking at the Comparability (Bioequivalence) of Two Forms of Semaglutide in Two Different Pen-injectors in People With Overweight or Obesity

Obesity | Overweight

Germany
Novo Nordisk A/S

Completed

A Research Study Looking at Similarity Between Once-weekly Semaglutide Versions for Different Injection Pens

Diabetes Mellitus, Type 2 | Healthy Volunteers

Germany
Novo Nordisk A/S

Completed

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Various Degrees of Impaired Renal Function

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Hungary, Czechia
Novo Nordisk A/S

Completed

A Research Study Looking at the Comparability (Bioequivalence) of Two Versions of Semaglutide

Obesity | Overweight | Healthy Volunteers

Germany
Novo Nordisk A/S

Completed

Investigation of the Effect of Upper Gastrointestinal Disease on the Pharmacokinetics of Oral Semaglutide in Subjects With Type 2 Diabetes.

Diabetes Mellitus, Type 2 | Diabetes

Germany
Novo Nordisk A/S

Completed

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Hepatic Impairment

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Poland, Slovakia, Czechia
Novo Nordisk A/S

Completed

Investigating the Pharmacokinetics, Safety and Tolerability After a Single Subcutaneous Injection of Semaglutide in Subjects With Mild, Moderate or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Diabetes Mellitus, Type 2 | Diabetes | Hepatic Impaired

Poland, Slovakia
Novo Nordisk A/S

Recruiting

A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose Weight

Obesity or Overweight

Taiwan, Japan
Novo Nordisk A/S

Completed

Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity (SELECT)

Obesity | Overweight

United States, France, Spain, Taiwan, United Kingdom, Germany, India, Brazil, Canada, Japan, Malaysia, Russian Federation, Australia, Norway, Mexico, Netherlands, Portugal, Hungary, Italy, Austria, Greece, South Africa, Turkey, Finland, Puerto Rico and more
Novo Nordisk A/S

Completed

Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in People Who Have a Body Weight Above the Healthy Range (OASIS 4)

Obesity | Overweight

Germany, United States, Canada, Poland
Novo Nordisk A/S

Completed

A Research Study on How Semaglutide Works in People With Fatty Liver Disease and Liver Damage

Non-alcoholic Steatohepatitis

United States, Spain, France, United Kingdom, Germany
Novo Nordisk A/S

Completed

Effect of Oral Contraceptives After Administration of Semaglutide in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Germany
Novo Nordisk A/S

Completed

A Research Study Comparing Blood Levels of Medicines NNC0194-0499 and Semaglutide Administered as a Combination Formulation Versus Two Separate Formulations

Non-alcoholic Steatohepatitis

Canada
Novo Nordisk A/S

Completed

A Clinical Trial Looking at the Comparability of 2 Different Forms of Semaglutide

Healthy Volunteers (Diabetes Mellitus, Type 2)

United Kingdom
Novo Nordisk A/S

Completed

A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Canada, Poland, South Africa, Slovakia
Novo Nordisk A/S

Completed

A Research Trial Looking at the Comparability of 2 Different Concentrations of Semaglutide for the 0.5 Milligram (mg) Dose

Diabetes Mellitus, Type 2 | Healthy Participants

United States
Novo Nordisk A/S

Completed

A Study Comparing the Injection Site Pain Experience After the Injection of Semaglutide B and Semaglutide D With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and Obesity

Healthy Volunteers Diabetes Mellitus, Type 2 | Healthy Volunteers Overweight | Healthy Volunteers Obesity

Netherlands
Novo Nordisk A/S

Terminated

A Research Study to Compare Two Forms of Semaglutide in Two Different Pen-injectors in People With Overweight or Obesity

Obesity | Overweight

Germany
Vanderbilt University Medical Center

Recruiting

GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab (GLP-TEP)

Type 1 Diabetes

United States
Axel Brandes
Hillerod Hospital, Denmark; Herlev and Gentofte Hospital; Svendborg Hospital; Hospital...

Withdrawn

Semaglutide for the Reduction of Arrhythmia Burden in Overweight AF Patients (SOCRATES-AF)

Atrial Fibrillation | Overweight and Obesity
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Novo...

Not yet recruiting

Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment

Obesity | Diabetes type1

United States
Odense University Hospital

Recruiting

The Effect of Oral Semaglutide on Bone Turnover in Patients With T2D: a Randomized Placebo-controlled Clinical Trial

Type 2 Diabetes | Osteopenia

Denmark
Anders Fink-Jensen, MD, DMSci

Recruiting

Does GLP-1RA Prevent Deterioration of Metabolic State in Prediabetic and Diabetic Patients Treated With Antipsychotic Medication?

Schizophrenia | Type 2 Diabetes | Metabolic Disturbance | Clozapine | Olanzapine | GLP-1

Denmark
Novo Nordisk A/S

Completed

A Research Study to Look at Similarity Between Semaglutide Versions in Different Injection Tools

Diabetes Mellitus, Type 2

Germany
Novo Nordisk A/S

Not yet recruiting

SEMA-CardioDiab HUNGARY: A Research Study to Understand the Effects of Oral Semaglutide on Blood Sugar Levels, Weight, and Cardiovascular Risk in People With Type 2 Diabetes Patients in Hungary

Type 2 Diabetes
Novo Nordisk A/S

Recruiting

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Saudi Arabia, as Part of Local Clinical Practice (PIONEER REAL)

Diabetes Mellitus, Type 2

Saudi Arabia
Novo Nordisk A/S

Completed

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Switzerland, as Part of Local Clinical Practice (PIONEER REAL)

Diabetes Mellitus, Type 2

Switzerland
Novo Nordisk A/S

Completed

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in the United Kingdom, as Part of Local Clinical Practice (PIONEER REAL)

Diabetes Mellitus, Type 2

United Kingdom
Novo Nordisk A/S

Completed

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Italy, as Part of Local Clinical Practice (PIONEER REAL)

Diabetes Mellitus, Type 2

Italy
Novo Nordisk A/S

Completed

Research Study Comparing New Tablets of Semaglutide in New Doses, in Healthy People

Diabetes Mellitus, Type 2

Germany
Novo Nordisk A/S

Completed

A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (D) Semaglutide Tablets

Type 2 Diabetes | Healthy Volunteers

Germany
Gan and Lee Pharmaceuticals, USA

Active, not recruiting

A Study of GZR18 Injection in Chinese Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes

China
Novo Nordisk A/S

Completed

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Denmark, as Part of Local Clinical Practice (PIONEER REAL)

Diabetes Mellitus, Type 2

Denmark
Novo Nordisk A/S

Completed

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Canada, as Part of Local Clinical Practice (PIONEER REAL)

Diabetes Mellitus, Type 2

Canada
Novo Nordisk A/S

Enrolling by invitation

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Israel, as Part of Local Clinical Practice (PIONEER REAL)

Diabetes Mellitus, Type 2

Israel
Novo Nordisk A/S

Completed

A Clinical Trial Comparing Semaglutide in Healthy People Who Eat and Take the Medicine at Different Times

Healthy Volunteers Type 2 Diabetes

United Kingdom
Novo Nordisk A/S

Completed

A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (C) Semaglutide Tablets

Type 2 Diabetes | Healthy Volunteers

Germany
Novo Nordisk A/S

Completed

Pharmacoscintigraphic Investigation of NN9924 in Healthy Male Subjects

Healthy | Diabetes

United Kingdom

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