Post-Marketing Surveillance (Special Use-results Surveillance) on Long-term Use With Ozempic®

Post-Marketing Surveillance (Special Use-results Surveillance) on Long-term Use With Ozempic®. A Multi-centre, Open-label, Non-interventional Post-marketing Study to Investigate the Long-term Safety and Effectiveness of Ozempic® (Semaglutide) in Japanese Patients With Type 2 Diabetes Mellitus Under Normal Clinical Practice Condition

The purpose of this study is to assess the safety of long-term treatment with Ozempic® in patients with type 2 diabetes mellitus. People will get Ozempic® as prescribed by their doctor. People will be in this study about 3 years. People above the age of 18 will be asked to fill in the quality of life (QOL) questionnaire (the QOL questionnaire is for the assessment of the influence of diabetes treatment on people's life). There is a possibility that people's blood sample would be provided to Novo Nordisk from their doctors in case of severe allergic reaction that might be caused by Ozempic®.

Study Overview

• Status: Completed
• Conditions: Diabetes Mellitus, Type 2
• Intervention / Treatment: Drug: semaglutide

• Study Type: Observational
• Enrollment (Actual): 3217

Contacts and Locations

Study Locations

• Japan
  • Aichi, Japan, 468-0009
    • TOSAKI Clinic for Diabetes and Endocrinology_Diabetes and Endocrinology
  • Aichi, Japan, 441-8087
    • Yamauchi Family Clinic
  • Aichi, Japan, 443-0022
    • Kobayashi Naika Clinic
  • Aichi, Japan, 446-0044
    • Wakaba Clinic
  • Aichi, Japan, 448-0852
    • Miyachi Clinic
  • Aichi, Japan, 450-0002
    • Meiekihigashi Clinic
  • Aichi, Japan, 451-8511
    • Meitetsu Hospital_Endocrinology and Metabolism
  • Aichi, Japan, 455-0815
    • Kusama Minato Clinic
  • Aichi, Japan, 455-0857
    • Nagashima Naika
  • Aichi, Japan, 458-0011
    • Aikawa Minnano Shinryojo
  • Aichi, Japan, 462-0037
    • Nakai Internal Clinic
  • Aichi, Japan, 462-0047
    • Takenaka Clinic
  • Aichi, Japan, 472-0014
    • Sawayaka Medical Clinic
  • Aichi, Japan, 484-0066
    • Inuyama Chuo General Hospital_Diabetes Internal Medicine
  • Aichi, Japan, 485-0044
    • Uenishi Internal Medicine Clinic
  • Aichi, Japan, 489-8642
    • Tosei General Hospital_Endocrinology and Metabolism
  • Aichi, Japan, 470-0345
    • Enomoto Naika
  • Aichi, Japan, 476-0011
    • Ogawa Clinic_Aichi
  • Akita, Japan, 017-8550
    • Odate Municipal General Hospital_Endocrinology and Metabolism
  • Akita, Japan, 016-0014
    • Noshiro Kosei Iryo Center_Diabetes and Metabolism
  • Akita, Japan, 018-4301
    • Kitaakita Shiritsu Yonaizawa Shinryojo
  • Aomori, Japan, 038-0011
    • Kakizaki Tonyobyo Naika Clinic
  • Aomori, Japan, 030-0823
    • Ohisama Clinic_Aomori
  • Arakawa-ku, Tokyo, Japan, 116-0012
    • Kumanomae Nishimura Naika Clinic_Internal Medicine
  • Asahikawa-shi, Hokkaido, Japan, 078-8211
    • Shimizu internal medicine clinic
  • Chiba, Japan, 292-0822
    • Kimitsu Chuo Hospital_Diabetology and Endocrinology
  • Chiba, Japan, 264-0017
    • Chiba Central Medical Center
  • Chiba, Japan, 271-0044
    • Shimada Iin
  • Chiba, Japan, 274-0805
    • Misaki Naika Clinic
  • Chiba, Japan, 277-0084
    • Shinkashiwa Clinic Tonyobyomirai
  • Chiba, Japan, 277-8567
    • The Jikei University Kashiwa Hospital_Diabetes and Endocrinology
  • Chiba, Japan, 279-0001
    • Tokyo Bay Urayasu Ichikawa Medical Center_Neph.& Endocrinology, Diabetes
  • Chiba, Japan, 286-0221
    • Toyo Clinic
  • Chiba, Japan, 290-0512
    • Chiba Cerebral and Cardiovascular Center
  • Chiba, Japan, 299-1144
    • Gengendo Kimitsu Hospital_Diabetes and Endocrinology
  • Chiba, Japan, 272-0033
    • Ichikawaekimae Ogawa Naika
  • Chiba, Japan, 274-0063
    • Endo Naika
  • Chiba, Japan, 283-0811
    • Saito Clinic
  • Chiba, Japan, 295-0021
    • Matsunaga Iin
  • Chiba-shi, Chiba, Japan, 260-0804
    • Akaicho Clinic
  • Chichibu, Japan, 368-0004
    • Mizuno Clinic
  • Chitose, Hokkaido, Japan, 066-0032
    • Hasegawa Medicine Clinic, Internal medicine
  • Ehime, Japan, 790-0026
    • Soyokaze CardioVascular Medicine and Diabetes Care
  • Ehime, Japan, 790-0034
    • Mikannohana Clinic
  • Ehime, Japan, 791-0281
    • Ehime Medical Center
  • Ehime, Japan, 791-8001
    • Yoshino Internal Medicine
  • Ehime, Japan, 791-8016
    • Matsuyama Daiichi Hospital_Diabetes Internal Medicine
  • Ehime, Japan, 791-8026
    • Saiseikai Matsuyama Hospital_Internal Medicine
  • Ehime, Japan, 792-0042
    • Ehime Prefectural Niihama Hp._Internal Medicine
  • Ehime, Japan, 792-8586
    • Jyuzen General Hospital_Internal Medicine
  • Ehime, Japan, 799-0193
    • Shikoku Central Hospital_Internal Medicine
  • Ehime, Japan, 794-0054
    • Hoshasen Daiichi Byoin_Internal Medicine
  • Ehime, Japan, 798-8510
    • Uwajima City Hospital_Endocrinology and Diabetes
  • Fukui, Japan, 910-0003
    • Fukui Chuoh Clinic
  • Fukui-shi, Fukui, Japan, 918-8503
    • Fukui Prefecture Saiseikai Hospital
  • Fukuoka, Japan, 815-0071
    • Clinic Masae Minami
  • Fukuoka, Japan, 800-0296
    • Kyushu Rosai Hospital_Diabetes and Metabolism
  • Fukuoka, Japan, 803-0845
    • Kuroki Hiro Clinic
  • Fukuoka, Japan, 804-0062
    • Hatanaka Naika Clinic
  • Fukuoka, Japan, 805-0031
    • Minezaki Naika Clinic
  • Fukuoka, Japan, 8100001
    • Hayashida Internal Medicine Clinic
  • Fukuoka, Japan, 811-2122
    • Okabe Hospital_Internal Medicine
  • Fukuoka, Japan, 812-0053
    • Okada Naika Clinic
  • Fukuoka, Japan, 815-0033
    • Tojitama Thyroid and Diabetes Clinic
  • Fukuoka, Japan, 818-0072
    • Iino Naika
  • Fukuoka, Japan, 819-1102
    • Kikuchi Naika Iin Maebaru
  • Fukuoka, Japan, 820-0076
    • Iizuka Kaho Hospital_Internal Medicine
  • Fukuoka, Japan, 832-0032
    • Ishibashi Iin
  • Fukuoka, Japan, 834-0115
    • Himeno Hospital
  • Fukuoka, Japan, 807-1112
    • Chiyo Clinic
  • Fukuoka, Japan, 811-3217
    • Fukutsu Naika Clinic
  • Fukuoka, Japan, 825-0002
    • Kuwano Naika Shonika Iin
  • Fukuoka, Japan, 833-0041
    • Chikugo Shiritsu Byoin_Endocrinology and Metabolism
  • Fukuoka-shi, Fukuoka, Japan, 819-0006
    • Futata Tetsuhiro Clinic Meinohama_Internal medicine
  • Fukushima, Japan, 961-8031
    • Iwashina Clinic
  • Fukushima, Japan, 973-8402
    • Taneda Clinic
  • Fukushima, Japan, 965-0853
    • Aizu Clinic
  • Fukushima-shi, Fukushima, Japan, 960-8001
    • Tani Naika Clinic, Internal medicine and diabets
  • Gifu, Japan, 501-6062
    • Matsunami General Hospital_Diabetes and Endocrinology
  • Gifu, Japan, 500-8381
    • Yamauchi Hospital_Internal Medicine
  • Gifu, Japan, 501-6003
    • Keyaki Clinic
  • Gifu, Japan, 504-0829
    • Asano Naika
  • Gifu, Japan, 506-0053
    • Ogawa Clinic_Gifu
  • Gifu, Japan, 501-6018
    • Kitada Internal Medicine Clinic
  • Gifu-shi, Gifu, Japan, 501-1194
    • Gifu University Hospital_The Third Dep of Internal Medicine
  • Gunma, Japan, 373-0036
    • Kawada Clinic
  • Gunma, Japan, 370-0069
    • Shimizu Naika
  • Gunma, Japan, 374-0052
    • Goga Internal Medicine Nire Clinic
  • Higashiosaka-shi, Osaka, Japan, 577 0803
    • Takekawa clinic, Internal Medicine
  • Hiroshima, Japan, 722-0014
    • Murakami Memorial Hospital_Diabetes Internal Medicine
  • Hiroshima, Japan, 722-0002
    • Tanabe Clinic
  • Hiroshima, Japan, 720-1131
    • Sato Family Clinic
  • Hiroshima, Japan, 733-0033
    • Hisayasu Iin
  • Hiroshima, Japan, 730-8619
    • Hiroshima Red Cross & Atomic-b_Endocrinology and Metabolism
  • Hiroshima, Japan, 739-0041
    • Higashihiroshima Medical Center_Endocrinology and Diabetes
  • Hokkaido, Japan, 060-0807
    • Sapporo Tonyobyo Kojosen Clinic
  • Hokkaido, Japan, 041-0821
    • Takasawa Diabetes Clinic
  • Hokkaido, Japan, 047-0021
    • Nakagaki Primary Care Clinic
  • Hokkaido, Japan, 053-0042
    • Ohata Naika Junkanki Clinic
  • Hokkaido, Japan, 060-0004
    • Sapporo Tonyobyo Kojosen Clinic Asty45
  • Hokkaido, Japan, 060-0042
    • Okamoto Naika Clinic_Hokkaido
  • Hokkaido, Japan, 063-0005
    • Hokkaido Medical Center
  • Hokkaido, Japan, 064-0824
    • Ito Hiroshi Naika Tonyobyonaika Clinic
  • Hokkaido, Japan, 068-0021
    • Yoshimura Tonyobyo Clinic
  • Hokkaido, Japan, 073-1105
    • Kagetsu Clinic
  • Hokkaido, Japan, 064-0917
    • Sapporo Yamahana Internal Medicine & Diabetes Clinic
  • Hokkaido, Japan, 078-8234
    • Yamagata Naika Clinic
  • Hokkaido, Japan, 080 0810
    • Honjo Naika Clinic
  • Hokkaido, Japan, 070-8530
    • Japanese Red Cross Asahikawa Hospital_Diabetes and Endocrinology
  • Hosu-gun, Ishikawa, Japan, 927-0053
    • Owari Cardiovascular Diabetes Medicine Clinic
  • Hyogogoken, Japan, 670-0837
    • Takabe Diabetes Clinic
  • Hyōgo, Japan, 650-0002
    • Shinkobe Okada Clinic
  • Hyōgo, Japan, 651-2135
    • Kaisei Clinic
  • Hyōgo, Japan, 656-0026
    • Hishikawa Naika Clinic
  • Hyōgo, Japan, 658-0064
    • Konan Medical Center_Diabetes and Endocrinology
  • Hyōgo, Japan, 658-0084
    • Sumiyoshigawa Byoin_Diabetes and Internal Medicine
  • Hyōgo, Japan, 659-8502
    • Ashiya Municipal Hospital_Diabetes and Endocrinology
  • Hyōgo, Japan, 660-0861
    • Yamasaki Family Clinic
  • Hyōgo, Japan, 661-0976
    • Taniguchi Medical Clinic
  • Hyōgo, Japan, 662-0075
    • Azuma Diabetes Clinic
  • Hyōgo, Japan, 665-0861
    • Nakayamadera Imai Clinic
  • Hyōgo, Japan, 670-0053
    • Tsukazaki Memorial Hospital_Internal Medicine
  • Hyōgo, Japan, 670-0801
    • Himeji St.Mary's Hospital_Gastroenterology - Hepatology
  • Hyōgo, Japan, 672-8035
    • Fukatsu Naika Shinryojo
  • Hyōgo, Japan, 673-0891
    • Yokota Medical Clinic
  • Hyōgo, Japan, 674-0063
    • Akashi Medical Center
  • Hyōgo, Japan, 675-0156
    • Tateya Clinic
  • Hyōgo, Japan, 675-0314
    • Hirai Naika Clinic
  • Hyōgo, Japan, 675-1316
    • Ono Hospital_Internal Medicine
  • Hyōgo, Japan, 675-8555
    • Hyogo Prefectural Kakogawa Medical Center_Diabetes and Endocrinology
  • Hyōgo, Japan, 678-0226
    • Obata Naika Tonyobyo Clinic
  • Hyōgo, Japan, 678-0232
    • Ako City Hospital_Internal Medicine
  • Hyōgo, Japan, 660-0892
    • Mitsuru Clinic
  • Ibaraki, Japan, 311-0113
    • Naka Kinen Clinic_Internal medicine
  • Ibaraki, Japan, 300-0012
    • Tsuchiura Shinryo Kenshin Center
  • Ibaraki, Japan, 300-0504
    • Iwaki Internal Medicine Clinic
  • Ibaraki, Japan, 306-0232
    • Itabashi Diabetes and Dermatology Medical Clinic
  • Ibaraki, Japan, 309-1703
    • Tomobe Central Clinic
  • Ibaraki, Japan, 310-0015
    • Mito Kyodo General Hospital_Diabetes and Endocrinology
  • Ibaraki, Japan, 314-0031
    • Maeda Hospital_Internal Medicine
  • Ibaraki, Japan, 300-0395
    • Tokyo Medical University Ibaraki Medical Center_Metabolism and Endocrinology
  • Iruma-shi, Saitama, Japan, 358 0003
    • Ohta Clinic, Internal Medicine
  • Ishikawa, Japan, 920-0012
    • Isobe Tounyoubyou Naika Clinic
  • Ishikawa, Japan, 920-0293
    • Kanazawa Medical University Hospital_Endocrinology and Metabolism
  • Kagawa, Japan, 761-1701
    • Akiyama Clinic
  • Kagawa, Japan, 762-0038
    • Takahashi Seikeigeka Iin
  • Kagawa, Japan, 765-0052
    • Osugi Neurosurgical Clinic
  • Kagawa, Japan, 769-2401
    • Tsuda Shinryojo
  • Kagawa, Japan, 760-8557
    • Kagawa Prefectural Central Hospital_Diabetes and Endocrinology
  • Kagawa, Japan, 765-0071
    • Iwamoto Internal Medicine Clinic_Diabetes Internal Medicine
  • Kagoshima, Japan, 890-0073
    • Uenomachi Kajiya Clinic
  • Kagoshima, Japan, 891-0133
    • Keiai Clinic
  • Kagoshima, Japan, 893-0014
    • Fukuda Iin
  • Kagoshima, Japan, 893-0022
    • Sonoda Clinic
  • Kagoshima, Japan, 895-0052
    • Wakamatsu Kinen Byoin_Internal Medicine
  • Kagoshima, Japan, 899-5421
    • Aira Tonyobyo Kojosen Naika Clinic
  • Kagoshima, Japan, 899-0214
    • Shimozono Clinic
  • Kagoshima-shi, Kagoshima, Japan, 890-0061
    • Tempozan Clinic of Internal Medicine
  • Kanagawa, Japan, 235-0045
    • H.E.C Science Clinic
  • Kanagawa, Japan, 259-1193
    • Tokai University Hospital_Cardiology
  • Kanagawa, Japan, 250-8558
    • Odawara Municipal Hospital_Diabetes and Endocrinology
  • Kanagawa, Japan, 231-8682
    • Yokohama City Minato Red Cross Hospital_Endocrinology
  • Kanagawa, Japan, 211-0004
    • Sun Marco Clinic
  • Kanagawa, Japan, 211-0041
    • Nakahara Medical Clinic
  • Kanagawa, Japan, 214-0014
    • Kubota Clinic
  • Kanagawa, Japan, 222-0033
    • Nishikawa Clinic
  • Kanagawa, Japan, 223-0052
    • Tsunashima East Internal med & Diabetes
  • Kanagawa, Japan, 236-0033
    • Kikuchi Naika Clinic_Kanagawa
  • Kanagawa, Japan, 236-0037
    • Yokohama Minami Kyousai Hospital_Cardiology
  • Kanagawa, Japan, 236-0058
    • Tagawa Naika Iin
  • Kanagawa, Japan, 243-0035
    • Suzuki Diabetes Clinic
  • Kanagawa, Japan, 247-0055
    • Shonan Takai Clinic_Internal Medicine
  • Kanagawa, Japan, 252-0131
    • Internal Medicine Clinic Kobayashi
  • Kanagawa, Japan, 252-0302
    • Higashirinkan Kaneshiro Diabetes Clinic
  • Kanagawa, Japan, 253-0042
    • Chigasaki Municipal Hospital_Endocrinology and Metabolism
  • Kanagawa, Japan, 254-8502
    • Hiratsuka Kyosai Hospital_Endocrinology and Metabolism
  • Kanagawa, Japan, 256-0816
    • Kyourindo Clinic
  • Kanagawa, Japan, 259-1126
    • Seichi Clinic
  • Kanagawa, Japan, 213-8507
    • Teikyo Univ.HP, Mizonokuchi_Fourth Internal Medicine
  • Kanagawa, Japan, 251-0052
    • Sawa Internal Medicine and Diabetes Clinic
  • Kanagawa, Japan, 245-8575
    • Yokohama Medical Center_Diabetes and Endocrinology
  • Kisarazu-shi, Chiba, Japan, 292-0038
    • Hotaruno hakuyukai Medical Corporation of Japan
  • Kobe, Hyogo, Japan, 650-0017
    • Kobe University Hospital_Diabetes and Endocrinology
  • Kochi, Japan, 780-0843
    • Ueta Iin
  • Kokuryō, Japan, 370-3573
    • Kikuchi Naika Clinic
  • Kokuryō, Japan, 372-0812
    • Morimura Clinic
  • Kokuryō, Japan, 373-0852
    • Arai Shinryojo
  • Kokuryō, Japan, 372-0007
    • Ringo no Hana Clinic
  • Koshigaya-shi,Saitama, Japan, 343 0828
    • Koshigaya Laketown Clinic
  • Kumamoto, Japan, 867-0041
    • Minamata City General Hospital & Medical Center_Metabolism
  • Kumamoto, Japan, 865-0064
    • Tamana Central Hospital_Diabetes and Endocrinology
  • Kyoto, Japan, 601-8325
    • Jujo Takeda Rehabilitation Hospital_Diabetes Internal Medicine
  • Kyoto, Japan, 604-0884
    • Kyoto Goshominami Harashima Clinic
  • Kyoto, Japan, 604-8416
    • Kamiuchi Naika Clinic
  • Kyoto, Japan, 606-0025
    • Toyoda Medical Clinic
  • Kyoto, Japan, 607-8494
    • Mata Clinic
  • Kyoto, Japan, 619-0224
    • Koide Iin
  • Kyoto, Japan, 623-0011
    • Ayabe City Hospital_Endocrinology and Diabetes
  • Kyoto, Japan, 612-0875
    • Oishi Naika Clinic
  • Mie, Japan, 516-8512
    • Japanese Red Cross Ise Hospital_Diabetes and Metabolism
  • Mie, Japan, 514-1101
    • Mie Chuo Medical Center_Internal Medicine
  • Mie, Japan, 516-0035
    • MG Clinic
  • Mie, Japan, 514-8507
    • Mie University Hospital_Diabetes and Endocrinology
  • Mitaka-shi, Tokyo, Japan, 181-0013
    • Kanno Naika_Internal Medicine
  • Miura-shi, Kanagawa, Japan, 238-0101
    • Miura Central Clinic
  • Miyagi, Japan, 981-3133
    • Shirai Healthcare Clinic Izumi-chuo
  • Miyagi, Japan, 982-0011
    • Suzuki Kenichi Naika Clinic
  • Miyagi, Japan, 985-0863
    • Yoshizumi Clinic Diabetes and Endocrinology
  • Miyagi, Japan, 988-0084
    • Morita Iin
  • Miyazaki, Japan, 880-0041
    • Koga General Hospital_Internal Medicine
  • Miyazaki, Japan, 889-4505
    • Sumi Byoin_Internal Medicine
  • Miyazaki, Japan, 880-0806
    • Mitsukawa Naika Iin
  • Miyazaki, Japan, 889-3141
    • Nichinan Chubu Hospital_Internal Medicine
  • Muroran-shi, Hokkaido, Japan, 050-0073
    • Ato internal medicine clinic, internal medicine
  • Nagano, Japan, 385-8558
    • Asama General Hospital_Diabetology
  • Nagano, Japan, 386-0004
    • Houden Clinic
  • Nagano, Japan, 386-8610
    • Shinshu Ueda Medical Center_Diabetes and Endocrinology
  • Nagano, Japan, 395-8502
    • Iida Municipal Hospital_Diabetes and Metabolism
  • Nagano, Japan, 395-8522
    • Kenwakai Hospital_Dialysis center
  • Nagano, Japan, 396-0033
    • Ina Central Hospital_Internal Medicine
  • Nagasaki, Japan, 850-0003
    • Saiseikai Nagasaki Hospital_Endocrinology and Diabetes
  • Nagasaki, Japan, 850-0831
    • Yuzu Clinic
  • Nagasaki, Japan, 851-0405
    • Onitsuka Naika Shokakika
  • Nagasaki, Japan, 852-8042
    • Miyazaki Naika
  • Nagasaki, Japan, 852-8107
    • Tetsuo Naika Iin
  • Nagasaki, Japan, 856-0831
    • Nakamura Iin
  • Nagasaki, Japan, 857-8511
    • Sasebo City General Hospital_Diabetes and Endocrinology
  • Nagasaki, Japan, 852-8511
    • Japanese Red Cross Nagasaki Genbaku Hospital_Metabolism and Endocrinology
  • Nara, Japan, 633-0064
    • Okamoto Internal Medicine and Pediatrics Clinic
  • Nara, Japan, 631-0003
    • Harada Tonyobyo Jin Naika Clinic
  • Nara, Japan, 631-0036
    • Hikari Clinic
  • Nara, Japan, 631-0813
    • Imamura Tonyobyo Naika Tsuda Geka Shinryojo
  • Nara, Japan, 631-0842
    • Furuya Clinic
  • Nara, Japan, 635-0015
    • Mashitani Naika Clinic
  • Nara, Japan, 635-0825
    • Ikenaka Naika Clinic
  • Nara, Japan, 636-0081
    • Seiwadai Clinic
  • Nara, Japan, 639-2251
    • Enomoto Clinic
  • Niigata, Japan, 942-0052
    • Minagawa Clinic Internal Medicine
  • Niigata, Japan, 943-0893
    • Takahashi Iin
  • Niigata, Japan, 949-3443
    • Uchiyama Iin
  • Niigata, Japan, 959-3193
    • Niigata Prefectural Sakamachi Hospital_Internal Medicine
  • Niigata-shi, Niigata, Japan, 950-1104
    • Saiseikai Niigata Hospital_Metabolism and Endocrinology
  • Nishinomiya-shi, Hyogo, Japan, 663-8501
    • Hyogo College Hospital_Diabetes and Endocrinology
  • Numakunai, Japan, 020-0403
    • Kaneko Gastroenterologist Internal Medicine
  • Numakunai, Japan, 021-0002
    • Abies Kanno Clinic
  • Numakunai, Japan, 024-0061
    • Kitakamiekimae Naika Clinic
  • Numakunai, Japan, 028-3695
    • Iwate Medical University Hospital_Diabetes and Metabolism
  • Okayama, Japan, 710-0051
    • Shigei Byoin_Internal Medicine
  • Okayama, Japan, 714-0043
    • Kasaoka Daiichi Hospital_Internal Medicine
  • Okayama, Japan, 708-0806
    • Obata Medical Clinic
  • Okayama, Japan, 711-0923
    • Kojima Marine Clinic
  • Okayama, Japan, 700-8558
    • Okayama University Hospital_Neph. and Diabetes, Metabolism
  • Okayama-shi, Okayama, Japan, 701-1192
    • Okayama Medical Center_Cardiology
  • Okinawa, Japan, 904-2143
    • Chibana Clinic
  • Okinawa, Japan, 901-2131
    • Tokuyama Clinic
  • Okinawa, Japan, 902-0062
    • Shuri Jokamachi Clinic
  • Okinawa, Japan, 904-2244
    • Sunagawa Medical Clinic
  • Okinawa, Japan, 905-0018
    • Taiyono Clinic
  • Osaka, Japan, 534-0021
    • Osaka City General Hospital
  • Osaka, Japan, 591-8006
    • Matsuda Gastroenterology and Diabetes Clinic
  • Osaka, Japan, 558-8558
    • Osaka General Medical Center_Cardiology
  • Osaka, Japan, 570-8540
    • Matsushita Memorial Hospital_Diabetes and Endocrinology
  • Osaka, Japan, 553-0003
    • Kansai Electric Power Hospital_Center for Diabetes
  • Osaka, Japan, 533-0001
    • Manabe Iin
  • Osaka, Japan, 536-0002
    • Yasuda Diabetes Clinic
  • Osaka, Japan, 543-0014
    • Kosugi Medical Clinic
  • Osaka, Japan, 558-0013
    • Ichiyoshi Iin
  • Osaka, Japan, 561-0884
    • Minamitani Clinic
  • Osaka, Japan, 563-0033
    • Nakanishi Clinic
  • Osaka, Japan, 565-0874
    • Maeda Clinic
  • Osaka, Japan, 569-0804
    • Sawaki Internal Medicine And Diabetes Clinic
  • Osaka, Japan, 575-8511
    • Tesseikai Noshinkeigeka Byoin_Cardiology
  • Osaka, Japan, 577-0802
    • Iwasaki Naika Clinic
  • Osaka, Japan, 581-0869
    • Ogawa Clinic
  • Osaka, Japan, 599-0202
    • Tamai Hospital_Diabetes Internal Medicine
  • Osaka, Japan, 599-8233
    • Minami Sakai Hospital_Internal Medicine
  • Osaka, Japan, 599-8247
    • Bellland Sogo Byoin_Endocrinology and Metabolism
  • Osaka, Japan, 530-0004
    • Tanaka Naika
  • Osaka, Japan, 530-0012
    • Nishimura Clinic
  • Osaka, Japan, 543-0035
    • Osaka Police Hospital_Diabetes and Endocrinology
  • Osaka, Japan, 553-0002
    • Matsumoto Clinic
  • Osaka, Japan, 561-0833
    • Jo's Medical Clinic
  • Osaka, Japan, 565-0842
    • Mori Clinic
  • Osaka, Japan, 567-0886
    • Masuda Clinic
  • Osaka, Japan, 569-8585
    • Hokusetsu General Hospital_Diabetes and Endocrinology
  • Osaka, Japan, 598-0011
    • Jonin Ueda Clinic
  • Osaka, Japan, 540-0006
    • Osaka National Hospital_Diabetes Internal Medicine
  • Osaka, Japan, 545-8586
    • Osaka City University Hospital_Metabolism and Endocrinology
  • Osaka-shi, Osaka, Japan, 533-0024
    • Yodogawa Christian Hospital
  • Osaka-shi, Osaka, Japan, 532 0003
    • Fukuda Clinic, Internal Medicine
  • Osaka-shi, Osaka, Japan, 536-0001
    • Saiseikai Noe Hospital
  • Osaki-shi, Miyagi, Japan, 989-6183
    • Osaki citizen hospital_Diabetes and metabolic disease
  • Ota-ku, Tokyo, Japan, 1430015
    • Iryo Houjin Shadan Sosyu-kai SATO MEDICAL CLINIC
  • Ota-ku, Tokyo, Japan, 144-0051
    • Shin Clinic
  • Saga, Japan, 847-8588
    • Karatsu Redcross Hospital_Diabetes Internal Medicine
  • Saga, Japan, 843-0024
    • Nagomitoiyashino Clinic
  • Saga, Japan, 845-0013
    • Noda Kousei Clinic
  • Saga, Japan, 847-0012
    • Noguchi Internal Clinic
  • Saga, Japan, 847-0062
    • Seki Clinic
  • Saga, Japan, 849-8577
    • Saga National Hospital_Internal Medicine
  • Saitama, Japan, 330-0074
    • Saitama Medical Center_Diabetes and Endocrinology
  • Saitama, Japan, 330-0846
    • Tanaka Clinic_Saitama
  • Saitama, Japan, 330-0855
    • Nakayama Clinic
  • Saitama, Japan, 331-0811
    • Ishizuka Medical Clinic
  • Saitama, Japan, 350-1231
    • Yokota Iin
  • Saitama, Japan, 350-2201
    • Kanazawa Clinic
  • Saitama, Japan, 356-0057
    • Mami clinic of internal medicine
  • Saitama, Japan, 359-1111
    • Imaki Clinic
  • Saitama, Japan, 352-0035
    • Josai Naika Clinic
  • Saitama, Japan, 356-0004
    • Negishi Naika Taisha Clinic
  • Saitama, Japan, 368-0072
    • Arafune Clinic
  • Sendai-shi, Miyagi, Japan, 983-0824
    • Matsudakai Tsurugaya Clinic, Internal medicine
  • Shiga, Japan, 520-0865
    • Kaneda Iin
  • Shiga, Japan, 526-8580
    • Nagahama City Hospital_Nephrology and Metabolism
  • Shiga, Japan, 520-0242
    • Tonyobyo Clinic Katata
  • Shiga, Japan, 523-0082
    • Omihachiman Community Medical Center_Metabolism and Endocrinology
  • Shimane, Japan, 691-0044
    • Kanazawa Diabetes & Osteoporosis Clinic
  • Shimane, Japan, 698-0046
    • Takase Naika
  • Shimane, Japan, 690-0883
    • Nabika Naika Clinic
  • Shimotsuga-gun, Tochigi, Japan, 321-0204
    • Sekiminatokinenkai Green Clinic
  • Shimotsuke-shi, Tochigi, Japan, 329-0433
    • Wakakusa Clinic
  • Shinjuku-ku, Tokyo, Japan, 162-8655
    • National Center for Global Health and Medicine_Cardiovascular Medicine
  • Shinjyuku-ku Tokyo, Japan, 160-0022
    • Medical corporation group lifestyle Tomonaga clinic_Internal Medicine
  • Shizuoka, Japan, 410-0041
    • Aso Clinic
  • Shizuoka, Japan, 410-0822
    • Mochizuki Naika Iin
  • Shizuoka, Japan, 411-0801
    • Yata Ikeda Iin
  • Shizuoka, Japan, 411-0816
    • Goto Clinic
  • Shizuoka, Japan, 420-0853
    • Japan Red Cross Shizuoka Hospital_Diabetes and Endocrinology
  • Shizuoka, Japan, 430-0802
    • Kikuchi Medical Clinic
  • Shizuoka, Japan, 431-3113
    • Hamamatsu-kita-Hospital_Internal Medicine
  • Shizuoka, Japan, 432-8580
    • Hamamatsu Medical Center_Endocrinology and Metabolism
  • Shizuoka-city, Shizuoka, Japan, 420-8630
    • Shizuoka city Shizuoka Hospital_Endocrinology and Metabolism
  • Soka-shi, Saitama, Japan, 340-0015
    • Soka Sugiura Internal Medicine Clinic
  • Suzaka-shi ,Nagano, Japan, 382-0091
    • Nagano Prefectural Shinshu Medical Center.
  • Tamana-shi, Kumamoto, Japan, 865 0016
    • Higashi Diabetes and Cardiovascular Clinic, Internal
  • Tochigi, Japan, 323-0022
    • Oyama East Clinic_Internal Medicine
  • Tochigi, Japan, 326-0053
    • Nagasaki Hospital_Internal Medicine
  • Tochigi, Japan, 321-1271
    • Kawakami Hospital_Internal Medicine
  • Tokorozawa-shi,Saitama, Japan, 359-1141
    • Saino Clinic
  • Tokushima, Japan, 779-3125
    • Tamaki Aozora Byoin_Diabetes and Endocrinology
  • Tokushima, Japan, 770-0022
    • Ooshima Clinic
  • Tokushima, Japan, 774-0014
    • Iwaki Clinic_Diabetes Internal Medicine
  • Tokyo, Japan, 105-8471
    • The Jikei University Hospital Dept of Diabetes, Metabolic
  • Tokyo, Japan, 102-0074
    • Kudanzaka Hospital_Internal Medicine
  • Tokyo, Japan, 103-0007
    • Hamacho Center Bldg. Clinic
  • Tokyo, Japan, 1040061
    • Ginza Yasue Clinic
  • Tokyo, Japan, 105-0012
    • Hosokawa Clinic
  • Tokyo, Japan, 108-0071
    • Shirokanedai Ogawa Clinic
  • Tokyo, Japan, 110-0015
    • Ueno Asakusa Street Clinic
  • Tokyo, Japan, 110-0016
    • Kyowa Iin
  • Tokyo, Japan, 111-0032
    • Kato Medical Clinic
  • Tokyo, Japan, 116-0014
    • Mikawashima Tower Clinic
  • Tokyo, Japan, 124-0025
    • Suzuki Diabetes Clinic_Tokyo
  • Tokyo, Japan, 125-8506
    • The Jikei University Katsushika Iryo Center_Diabetes and Endocrinology
  • Tokyo, Japan, 133-0051
    • Seikodo Clinic
  • Tokyo, Japan, 135-0002
    • Asoka Hospital_Internal Medicine
  • Tokyo, Japan, 135-0042
    • Okamoto Naika Clinic
  • Tokyo, Japan, 135-8550
    • Cancer Institute Ariake Hosp._Diabetes and Metabolism
  • Tokyo, Japan, 142-0042
    • Togoshi Perk Clinic
  • Tokyo, Japan, 143-0016
    • Makita General Hospital_Diabetes Internal Medicine
  • Tokyo, Japan, 143-8541
    • Toho University Omori Medical Center_Diab Metab Endo
  • Tokyo, Japan, 144-0052
    • Kamata Diabetes Clinic
  • Tokyo, Japan, 145-0072
    • Takeuchi Naika Shonika Iin
  • Tokyo, Japan, 150-0013
    • Matsuura Clinic
  • Tokyo, Japan, 154-0017
    • Kokubo Clinic
  • Tokyo, Japan, 155-0031
    • Shimokitazawa Hospital_Diabetes Center
  • Tokyo, Japan, 160-8488
    • Ohkubo Hospital_Endocrinology and Metabolism
  • Tokyo, Japan, 165-8906
    • Tokyo General Hospital_Diabetes and Metabolism
  • Tokyo, Japan, 176-8530
    • Nerima General Hospital_Internal Medicine
  • Tokyo, Japan, 178-0063
    • KAWASAKI internal medicine clinic & Diabetic
  • Tokyo, Japan, 178-0064
    • Hoya Iin
  • Tokyo, Japan, 186-0002
    • Clinic Mirai Kunitachi
  • Tokyo, Japan, 190-0023
    • Clinic Mirai Tachikawa
  • Tokyo, Japan, 192-0083
    • Hachioji Diabetes Clinic
  • Tokyo, Japan, 194-0013
    • Sato Juichi Clinic
  • Tokyo, Japan, 198-0042
    • Ome Municipal General Hospital_Endocrinology and Metabolism
  • Tokyo, Japan, 206-0033
    • Tamacenter Clinic Mirai
  • Tokyo, Japan, 101-8643
    • Mitsui Memorial Hospital_Diabetes and Metabolism
  • Tokyo, Japan, 166-0004
    • Ekimae Tsunoda Clinic
  • Tokyo, Japan, 193-0998
    • Tokyo Medical Univ. Hachioji_Diabetes and Endocrinology
  • Tokyo, Japan, 203-0053
    • Higashikurume Ekimae Clinic
  • Tokyo, Japan, 108-8642
    • Kitasato Institute Hospital_Diabetes Center
  • Tokyo, Japan, 153-0051
    • Mishuku Hospital_Endocrinology and Metabolism
  • Tomigusuku-shi, Okinawa, Japan, 901-0244
    • Tanaka Clinic
  • Tottori, Japan, 683-8504
    • Tottori University Hospital
  • Tottori, Japan, 680-0935
    • Satoni Denen Clinic
  • Toyama, Japan, 939-0243
    • Shinseikai Toyama Hospital_Diabetes Center
  • Toyama-shi, Toyama, Japan, 930-0194
    • Toyama University Hosp., Dept. of Diabetes, Metabo.& Endoc.
  • Toyonaka-shi, Osaka, Japan, 560-0082
    • Senrichuo Ekimae Clinic
  • Wakayama, Japan, 640-8558
    • Japanese Red Cross Wakayama Medical Center_Diabetology and Endocrinology
  • Yamagata, Japan, 990-8510
    • Tohoku Central Hospital_Diabetes Internal Medicine
  • Yamagata, Japan, 996-0035
    • Kochi Iin
  • Yamaguchi, Japan, 756-0095
    • Yamaguchi Rosai Hospital_Diabetes and Endocrinology
  • Yamaguchi, Japan, 740-0034
    • Iwasaki Naika Iin
  • Yamaguchi, Japan, 742-1102
    • Okino Naika Tonyobyo Clinic
  • Yamanashi, Japan, 405-0072
    • Nakazato Medical Clinic
  • Yanagawa-shi, Fukuoka, Japan, 832-0059
    • Nagata Hospital
  • Yokohama, Kanagawa, Japan, 222-0036
    • Yokohama Rosai Hospital
  • Ōita, Japan, 870 8511
    • Oita Prefectural Hospital_Endocrinology and Metabolism
  • Ōita, Japan, 870-0935
    • Kayashima Clinic
  • Ōita, Japan, 875-0051
    • Cosmos Byoin_Internal Medicine
  • Ōita, Japan, 879-7301
    • Okamoto Clinic for Diabetes and Endocrinology
  • Ōita, Japan, 879-0627
    • Takada Chuo Byoin_Diabetes Internal Medicine
  • Fukushima, Japan
    • Koriyama-shi, Fukushima, Fukushima, Japan, Japan, 963-8851
      • Seino Internal Medicine Clinic_Internal medicine
  • Kanagawa
    • Yamato-shi, Kanagawa, Japan, 242-0004
      • Tsuruma Kaneshiro Diabetes Clinic_Internal medicine
  • Kanagawa, Japan
    • Kamakura-shi, Kanagawa, Kanagawa, Japan, Japan, 247 0056
      • Takai Internal Medicine Clinic_Internal Medicine
    • Kawasaki-shi, Kanagawa, Japan, Japan, 212 0024
      • Matsuba Clinic_Internal Medicine
  • Kumamoto, Japan
    • Kumamoto, Kumamoto, Japan, Japan, 862-0976
      • Jinnouchi Hospital_Internal Medicine
  • Miyazaki
    • Miyazaki, Miyazaki, Japan, 880-0034
      • Heiwadai Hospital_Internal Medicine
  • Oita, Japan
    • Ōita, Oita, Japan, Japan, 870 0039
      • Abe Diabetes Clinic_Internal Medicine
  • Osaka, Japan
    • Izumisano, Osaka, Japan, Japan, 598 0048
      • Iryo Houjin Hakuunkai Ryoya Komatsu Clinic,Internal medicine
  • Saitama, Japan
    • Kawagoe-shi, Saitama, Japan, Japan, 350-0851
      • Asano Clinic
  • Tokyo, Japan
    • Minatoku, Tokyo, Japan, Japan, 108 0073
      • Tokyo Saiseikai Central Hospitl, Internal Med
  • Toyama, Japan
    • Imizu-shi, Toyama, Japan, Japan, 939 0363
      • Ohgaku Clinic, Internal Medicine

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Japanese people with type 2 diabetes being treated in normal clinical practice conditions

Description

Inclusion Criteria:

• Signed consent obtained before any study-related activities (study-related activities are any procedure related to recording of data according to the protocol).
• The decision to initiate treatment with commercially available Ozempic® has been made by the patient/Legally Acceptable Representative (LAR) and the treating physician before and independently from the decision to include the patient in this study.
• Patients with Diabetes Mellitus, Type 2 (T2DM) who the physician has decided to start treatment with Ozempic®.
• Male or female, no age limitation.

Exclusion Criteria:

• Previous participation in this study. Participation is defined as having given informed consent in this study.
• Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation.
• Patients who fall under contraindications to the label.
• Patients who are or have previously been treated with Ozempic®.
• Female who is pregnant, breast-feeding or intends to become pregnant.

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Ozempic®; Japanese people with type 2 diabetes being treated in normal clinical practice conditions	Drug: semaglutide; Patients will be treated with commercially available Ozempic® according to routine clinical practice at the discretion of the treating physician. The treating physician's decision to initiate treatment with Ozempic® is independent of the decision to include the patient in the study.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of adverse events (AEs)	Count	From baseline (day 0) to end of study (month 36)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of serious adverse reactions (SARs)	Count	From baseline (day 0) to end of study (month 36)
Number of adverse reactions (ARs)	Count	From baseline (day 0) to end of study (month 36)
Number of serious adverse events (SAEs)	Count	From baseline (day 0) to end of study (month 36)
Change in glycosylated haemoglobin A1c (HbA1c)	Percent	From baseline (day 0) to end of study (month 36)
Change in fasting plasma glucose (FPG)	mg/dL	From baseline (day 0) to end of study (month 36)
Change in body weight	kg	From baseline (day 0) to end of study (month 36)
Change in patient-reported outcomes (PROs) using the Diabetes Therapy-Related QOL (DTR-QOL) questionnaire - total score	DTR-QOL assesses the influence of diabetes treatment on the individual health related quality of life on 4 domains: "burden on social activities and daily activities", "anxiety and dissatisfaction with treatment", "hypoglycaemia" and "satisfaction with treatment". DTR-QOL contains 29 items. The response scale used is a 7-point Likert scale (1: Strongly agree - 7: Strongly disagree)	From baseline (day 0) to visit 5 (month 12)
Change in patient-reported outcomes (PROs) using the Diabetes Therapy-Related QOL (DTR-QOL) questionnaire - burden of social activities and daily activities	DTR-QOL assesses the influence of diabetes treatment on the individual health related quality of life on 4 domains: "burden on social activities and daily activities", "anxiety and dissatisfaction with treatment", "hypoglycaemia" and "satisfaction with treatment". DTR-QOL contains 29 items. The response scale used is a 7-point Likert scale (1: Strongly agree - 7: Strongly disagree)	From baseline (day 0) to visit 5 (month 12)
Change in patient-reported outcomes (PROs) using the Diabetes Therapy-Related QOL (DTR-QOL) questionnaire - anxiety and dissatisfaction with treatment	DTR-QOL assesses the influence of diabetes treatment on the individual health related quality of life on 4 domains: "burden on social activities and daily activities", "anxiety and dissatisfaction with treatment", "hypoglycaemia" and "satisfaction with treatment". DTR-QOL contains 29 items. The response scale used is a 7-point Likert scale (1: Strongly agree - 7: Strongly disagree)	From baseline (day 0) to visit 5 (month 12)
Change in patient-reported outcomes (PROs) using the Diabetes Therapy-Related QOL (DTR-QOL) questionnaire - hypoglycaemia	DTR-QOL assesses the influence of diabetes treatment on the individual health related quality of life on 4 domains: "burden on social activities and daily activities", "anxiety and dissatisfaction with treatment", "hypoglycaemia" and "satisfaction with treatment". DTR-QOL contains 29 items. The response scale used is a 7-point Likert scale (1: Strongly agree - 7: Strongly disagree)	From baseline (day 0) to visit 5 (month 12)
Change in patient-reported outcomes (PROs) using the Diabetes Therapy-Related QOL (DTR-QOL) questionnaire - satisfaction with treatment	DTR-QOL assesses the influence of diabetes treatment on the individual health related quality of life on 4 domains: "burden on social activities and daily activities", "anxiety and dissatisfaction with treatment", "hypoglycaemia" and "satisfaction with treatment". DTR-QOL contains 29 items. The response scale used is a 7-point Likert scale (1: Strongly agree - 7: Strongly disagree)	From baseline (day 0) to visit 5 (month 12)

Collaborators and Investigators

• Sponsor: Novo Nordisk A/S
• Investigators: Study Director: Clinical Reporting Anchor and Disclosure (1452), Novo Nordisk A/S

Study record dates

Study Major Dates

• Study Start (Actual): July 27, 2020
• Primary Completion (Actual): May 12, 2025
• Study Completion (Actual): May 12, 2025

Study Registration Dates

• First Submitted: July 10, 2020
• First Submitted That Met QC Criteria: July 10, 2020
• First Posted (Actual): July 14, 2020

Study Record Updates

• Last Update Posted (Actual): May 19, 2026
• Last Update Submitted That Met QC Criteria: May 18, 2026
• Last Verified: May 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Endocrine System Diseases; Metabolic Diseases; Glucose Metabolism Disorders; Diabetes Mellitus; Nutritional and Metabolic Diseases; Diabetes Mellitus, Type 2; semaglutide
• Other Study ID Numbers: NN9535-4347; U1111-1187-9072 (Other Identifier: World Health Organization (WHO))

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: According to the Novo Nordisk disclosure commitment on novonordisk-trials.com

Drug and device information, study documents

• Studies a U.S. FDA-regulated device product: No