Search clinical trials for: Placebo added to Hydroxyurea

Total 1191 results

University of Virginia

Withdrawn

Effects of Sho-saiko-to, a Herbal Formula, in Reducing Viral Load in Hepatitis C

Hepatitis C Virus
NYU Langone Health

Active, not recruiting

Study of the Safety and Efficacy of a Caffeine-based Antifibrosis Cream in Patients With Breast Cancer Undergoing Radiation Therapy (ReDCoAT)

Carcinoma Breast

United States
Amgen

Completed

Safety and Efficacy Study to Evaluate Denosumab Compared With Zoledronic Acid in Postmenopausal Women With Osteoporosis

Post Menopausal Osteoporosis

Canada, Denmark, United States, Belgium, Poland, Spain, Australia
Washington University School of Medicine
American Academy of Pediatrics; Ambulatory Pediatric Association

Terminated

Montelukast Added to Standard Therapy for Acute Asthma in Children Age 6-14 Years

Asthma

United States
Institut de Recherche pour le Developpement
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Nevirapine Plus Zidovudine to Prevent Perinatal HIV in Thailand

HIV Infections | Pregnancy

Thailand
Leukemia Research Fund

Completed

Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United Kingdom
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-3 (GAUSS-3)

Hyperlipidemia

Canada, Denmark, France, United States, Czechia, New Zealand, Australia, South Africa, Italy, United Kingdom, Netherlands, Germany, Norway
Gilead Sciences

Terminated

Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis (STELLAR-3)

Nonalcoholic Steatohepatitis

Hong Kong, United States, Spain, United Kingdom, Australia, Taiwan, Belgium, Canada, India, Japan, Korea, Republic of, Singapore, Puerto Rico, France, Israel, Austria, Germany, Italy, Malaysia, New Zealand, Mexico, Poland, Switzerland, Netherlan... and more
Merck Sharp & Dohme LLC

Completed

Telcagepant (MK-0974) Treatment of Migraine in Participants With Stable Vascular Disease (MK-0974-034)

Vascular Diseases | Peripheral Vascular Diseases | Migraine Disorders | Heart Disease | Cerebrovascular Accident | TIA (Transient Ischemic Attack)
University of Chile

Recruiting

A Software to Prevent Delirium (PREVEDEL) in Hospitalized Older Adults (PREVEDEL)

Neurologic Manifestations | Delirium | Confusion | Neurobehavioral Manifestations

Chile
Merck Sharp & Dohme LLC

Terminated

Study of MK-1972 in Human Immunodeficiency Virus (HIV)-1 Infected Participants Who Have Not Previously Received Antiretroviral Therapy (MK-1972-003)

HIV-1 Infection
Bristol-Myers Squibb
Triangle Pharmaceuticals; Pharmacia and Upjohn

Terminated

The Safety and Effectiveness of Didanosine Plus Stavudine Plus Delavirdine Mesylate Plus MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Preventing Problem Behavior Among Middle School Students

Health Promotion | Substance Use Disorders
Gilead Sciences

Terminated

Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (STELLAR-4)

Nonalcoholic Steatohepatitis

United States, Spain, Hong Kong, Canada, Belgium, Australia, Taiwan, India, Japan, Korea, Republic of, Singapore, United Kingdom, Israel, Puerto Rico, France, New Zealand, Germany, Austria, Italy, Mexico, Poland, Switzerland
University of Texas Southwestern Medical Center
National Institute on Drug Abuse (NIDA)

Recruiting

Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2) (CURB-2)

Cocaine Use Disorder

United States
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 in Healthy Overweight/Obese Volunteers

Obesity

United States
Lawson Health Research Institute

Completed

Micronutrient Supplemented Probiotic Yogurt for HIV/AIDS and Other Immunodeficiencies

HIV Infections | Cancer, Second Primary

Canada
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes

Obesity | Type 2 Diabetes Mellitus in Obese

United States
Lesaffre International
Eurofins Optimed

Terminated

Effect of Saccharomyces Cerevisiae on Improving the Effectiveness of Conventional Treatment of Vulvo-vaginal Candidiasis

Vulvo-vaginal Candidiasis

France
Jemincare

Recruiting

Safety, Tolerability of JMKX003002 in Phase 1 Study in Healthy Subjects

Safety and Tolerability

China
Epygenix

Not yet recruiting

EPX-100 (Clemizole Hydrochloride) as Adjunctive Therapy in Children With Lennox Gastaut Syndrome (LGS)

Lennox Gastaut Syndrome
Novartis

Completed

Efficacy of Aliskiren Compared to Ramipril in the Treatment of Moderate Systolic Hypertensive Patients (ALIAS)

Essential Hypertension

France
AstraZeneca

Completed

Study to Examine Safety, Tolerability, and Effect on Body Weight of Metreleptin Administered in Conjunction With Pramlintide in Obese and Overweight Subjects

Obesity | Overweight

United States
New York State Psychiatric Institute

Completed

Mechanisms of Antidepressant Non-Response in Late-Life Depression

Major Depressive Disorder

United States
Boehringer Ingelheim

Completed

Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of BI 655075 (Idarucizumab) Administered Alone or With Dabigatran Etexilate in Japanese Healthy Subjects

Healthy

Japan
Gilead Sciences

Completed

Effect of Oral GS-6615 on Dofetilide-Induced QT Prolongation, Safety, and Tolerability in Healthy Adults

Long QT Syndrome

United States
University of Barcelona

Enrolling by invitation

Efficacy of a Probiotic and Microbiological Analysis on Oral Complications Induced by Antineoplastic Therapies in Patients With HNC

Quality of Life | Periodontal Diseases | Dysbiosis | Dental Plaque | Xerostomia | Oral Mucositis

Spain
Jemincare
Zhejiang Hangyu Pharmaceutical Co., Ltd

Recruiting

Phase 1 Clinical Study of JMKX003142 Tablets

Safety and Tolerability

China
University Hospital, Grenoble
AGIR à Dom

Completed

Efficacy and Safety of 3% Hypertonic Saline Inhalation (24h vs 72h) to Treat Acute Bronchiolitis in Hospitalized Infants (BRONDUSAL)

Bronchiolitis

France
University of Texas Southwestern Medical Center
Gilead Sciences

Terminated

Safety and Efficacy Trial to Treat Diastolic Heart Failure Using Ambrisentan

Pulmonary Hypertension | Heart Failure With Preserved Ejection Fraction

United States
Sanaullah Iqbal
University of the Punjab

Completed

Nutritional Intervention For The Treatment Of Uncomplicated SAM (SAM)

Child Nutrition Disorders

Pakistan
Vidasym, Inc.

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of VS 105

Chronic-kidney Disease Stage 5D on Stable Hemodialysis

United States
Aswan University Hospital

Unknown

17-Alpha-Hydroxyprogesterone Caproate in Pregnant Women With Placenta Previa

Placenta Previa

Egypt
University of California, Los Angeles

Recruiting

Metformin Treatment in Progressive Multiple Sclerosis

Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United States
Gilead Sciences

Withdrawn

Study to Evaluate Safety, Tolerability, and Efficacy of GS-5718 in Participants With Active Rheumatoid Arthritis Who Have an Inadequate Response to Disease-modifying Antirheumatic Drug(s) (bDMARDs) Treatment

Rheumatoid Arthritis
Dongzhimen Hospital, Beijing

Completed

Efficacy and Safety of Tianzhi Granule in Mild to Moderate Vascular Dementia

Vascular Dementia

China
Shionogi

Completed

A Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Otherwise Healthy Patients With Influenza (CAPSTONE 1)

Influenza
GlaxoSmithKline

Completed

A Study of Intravenous Zanamivir Versus Oral Oseltamivir in Adults and Adolescents Hospitalized With Influenza (ZORO)

Influenza, Human

Australia, Taiwan, Korea, Republic of, United States, Belgium, Canada, Germany, South Africa, Spain, United Kingdom, New Zealand, Thailand, India, China, Brazil, Hong Kong, Slovakia, Russian Federation, Denmark, Mexico, Czechia, H... and more
Gilead Sciences
Galapagos NV

Withdrawn

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Have an Inadequate Response to Biologic Disease-Modifying Antirheumatic Drug Therapy (SEALION1-IR)

Ankylosing Spondylitis
EMD Serono

Terminated

A Phase 2 Study of Atacicept in Subjects With Relapsing Multiple Sclerosis (ATAMS) (ATAMS)

Relapsing Multiple Sclerosis

United States, Sweden, Australia, Czech Republic, Russian Federation, Spain, United Kingdom, Germany, Lithuania, Ukraine, Netherlands, Canada, France, Austria, Lebanon, Switzerland, Belgium
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Pharmacokinetics of Different Regimens of Indacaterol

Persistent Asthma

United States, Netherlands, United Kingdom, France, Germany, Jordan
Verona Pharma plc
Iqvia Pty Ltd; LGC Limited

Completed

Study Investigating the Effect of 4 Doses of RPL554 Given in Addition to Tiotropium to Patients With COPD

COPD

United States
Boehringer Ingelheim

Completed

Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Doses of BI 187004 CL

Healthy

Germany
Boehringer Ingelheim

Completed

Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Doses of BI 163538 XX

Healthy

Germany
Novartis

Completed

Comparison of Efficacy of Indacaterol Versus Placebo Over 12 Weeks

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca

Completed

The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers

Healthy | Memory Impairment

United States
Gilead Sciences
Galapagos NV

Withdrawn

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Are Naive to Biologic Disease-Modifying Antirheumatic Drug Therapy (SEALION2-NAÏVE)

Ankylosing Spondylitis
Samsung Medical Center

Completed

Efficacy of Motilitone on Gastric Accommodation in Healthy Adult Patients: Evaluation Using MRI Method

Dyspepsia

Korea, Republic of
Novartis Pharmaceuticals

Completed

Study of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inclisiran in Chinese Participants With Elevated Serum LDL-C (ORION-14)

Hyperlipidemia

China
Organon and Co

Completed

A Two-Part 26-Week Study of Etoricoxib as Treatment for Ankylosing Spondylitis (AS) (MK-0663-108)

Spondylitis, Ankylosing

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