Search clinical trials for: Placebo macitentan

Total 53964 results

Actelion

Terminated

Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT Instrument (SYMPHONYext)

Pulmonary Arterial Hypertension

United States
Amsterdam UMC, location VUmc

Unknown

Goal Oriented Strategy to Preserve Ejection Fraction Trial (GOSPEL)

Pulmonary Arterial Hypertension

Netherlands
Actelion

Completed

Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAH

Pulmonary Arterial Hypertension

Spain, France, Italy
Actelion

Recruiting

A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH) (TOMORROW)

Pulmonary Arterial Hypertension

United States, Korea, Republic of, Spain, Malaysia, China, Hungary, Mexico, Poland, Australia, Austria, Brazil, Canada, Colombia, France, Israel, Philippines, Portugal, Russian Federation, South Africa, Thailand, Ukraine, Vietnam, F...
Actelion

Withdrawn

A Study of Macitentan in Children Below 2 Years of Age

Arterial Hypertension, Pulmonary

Poland, Germany
Actelion

Completed

Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (MERIT-2)

Chronic Thromboembolic Pulmonary Hypertension

Poland, Ukraine, United Kingdom, China, Russian Federation, Belgium, Germany, Thailand, Hungary, France, Lithuania, Czechia, Mexico, Switzerland, Turkey
Actelion

Completed

A Study of Two Macitentan Formulations in Healthy Adult Participants

Healthy

Belgium
Actelion

Completed

The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension (TRITON)

Pulmonary Arterial Hypertension

United States, Spain, Denmark, Canada, Germany, United Kingdom, Belgium, Austria, Netherlands, Australia, France, Ireland, Sweden, Italy, Switzerland
Ege University

Completed

Care to Caregiver: The Effect of Reflexology on Sleep and Anxiety of Cancer Caregiver

Sleep | Anxiety

Turkey
Actelion

Terminated

Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma

Glioblastoma

United States
Washington University School of Medicine

Completed

Alirocumab and Reverse Cholesterol Transport

Atherosclerosis | Coronary Heart Disease

United States
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Low Dose IL-2 Therapy in Patients With a Depressive Episode in the Course of a Bipolar Disorder (DEPIL-2)

Bipolar Depression

France
Orphan Australia

Completed

VSL#3 Versus Placebo in Maintenance of Remission in Crohn's Disease

Crohn's Disease

Australia
Nowarta Biopharma Inc

Completed

A Phase I/II Double-blind Safety and Efficacy Evaluation of Nowarta110 in Patients With Plantar Warts

Plantar Warts

United States
Chinese University of Hong Kong

Recruiting

RCT for Yinqiaosan-Maxingganshitang in the Treatment of COVID-19

COVID-19

Hong Kong
National University of Malaysia
Malaysia Palm Oil Board

Unknown

Supplementation of Oil Palm Phenolics to Healthy Participants (SPIRAL)

Cardiovascular Diseases | Hypercholesterolemia | Hyperlipidemias

Malaysia
Gladwin, Mark, MD
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age (Nitrite)

Sedentary Lifestyle | Frailty | Aging

United States
Mersin University

Completed

The Effect of Post-Cesarean Section Acupressure on the Severity of Pain and First Mobilization Distance (Acupress)

Pain | Mobilization

Turkey
University of South Carolina
U.S. Army Medical Research and Development Command

Completed

Dietary Seaweed and Early Breast Cancer: A Randomized Trial

Seaweed Associated Changes in Healthy Subjects

United States
John Paul II Hospital, Krakow
National Center for Research and Development, Poland; KCRI

Active, not recruiting

Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With No-option Critical Limb Ischemia (N-O CLI)

Critical Limb Ischemia

Poland
John Paul II Hospital, Krakow
National Center for Research and Development, Poland; KCRI

Completed

Randomized Clinical Trial to Evaluate the Regenerative Capacity of CardioCell in Patients With Chronic Ischaemic Heart Failure (CIHF)

Heart Failure

Poland
LEO Pharma

Completed

Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).

Atopic Dermatitis

United States, Belgium, Canada, Australia, France, Germany, Japan, Netherlands, Poland, United Kingdom
Guang'anmen Hospital of China Academy of Chinese...
Hubei Hospital of Traditional Chinese Medicine; Hebei Yiling Hospital; The First... and other collaborators

Unknown

The Multi-Centric Clinical Study of Chinese Medicine Intervention on Diabetes Distal Symmetric Polyneuropathy.

Type 2 Diabetes Mellitus
Resverlogix Corp

Not yet recruiting

A Two-Part Phase 2a Study of RVX000222 in Patients With End-Stage Renal Disease Treated With Hemodialysis

Kidney Failure, Chronic
Fengmei Lian
Guang'anmen Hospital of China Academy of Chinese Medical Sciences; Hubei Hospital... and other collaborators

Unknown

Clinical Study of Tang Wang Prescription Intervene Diabetic Non-proliferative Retinopathy

Type2 Diabetes | Diabetic Non-proliferative Retinopathy
John Paul II Hospital, Krakow
National Center for Research and Development, Poland; KCRI

Completed

Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With Acute Myocardial Infarction (AMI)

Myocardial Infarction

Poland
Actelion

Completed

Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male Subjects

Healthy Subjects

Germany
Shengjing Hospital

Completed

Efficacy of Chinese Herbal Medicine Xiaojidaozhi Decoction in the Treatment of Childhood Constipation

Constipation | Chinese Herbal Medicine

China
AstraZeneca

Completed

A Study of AZD8233 in Participants With Dyslipidemia. (HAYATE)

Dyslipidemia

Japan
Albert Einstein College of Medicine

Completed

Sodium Bicarbonate Supplementation in Chronic Kidney Disease Evaluation of Dose Response, Safety and Beneficial Effects

Chronic Kidney Disease

United States
Actelion
Canadian Heart Research Centre

Completed

Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program (PAH QuERI Ext)

Pulmonary Arterial Hypertension

United States, Puerto Rico
Actelion

Completed

Comparison of the Pharmacokinetic Properties of Two Tablet Formulations of Macitentan in Healthy Adults

Healthy Subjects

Czech Republic
Sidney Kimmel Comprehensive Cancer Center at Johns...
Greater Washington Community Foundation

Terminated

Muscadine Plus (MPX) In Men With Prostate Cancer

Adenocarcinoma of the Prostate

United States
Novartis Pharmaceuticals

Completed

A Study of Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (ORION-5)

Homozygous Familial Hypercholesterolemia

Hong Kong, Israel, Russian Federation, Serbia, South Africa, Taiwan, Turkey, Ukraine
Fengmei Lian
Peking Union Medical College Hospital; Huashan Hospital; Chengdu University of... and other collaborators

Unknown

Post-marketing Evaluation of Mudan Granule Intervention on Type 2 Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy Type 2

China
Contera Pharma
Bukwang Pharmaceutical

Completed

A Study in Parkinson's Disease in Patients With Moderate to Severe Dyskinesia (ASTORIA)

Dyskinesias

France, Germany, Italy, Korea, Republic of, Spain
University of California, San Diego

Terminated

Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC (ILEUS)

Ileus

United States
Novartis

Completed

Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Compared to Placebo in Subjects With Acute Blunt Trauma Injuries

Acute Blunt Soft Tissue Injuries/Contusions

United States
William Beaumont Hospitals

Terminated

Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis (PRONE)

Fibrosis, Liver | Cirrhosis, Liver | Steatohepatitis, Nonalcoholic | Fatty Liver Disease

United States
Vanderbilt University
Merck Sharp & Dohme LLC

Withdrawn

Vorapaxar and Lower Extremity Bypass Grafts

Peripheral Artery Disease
Kuopio University Hospital

Withdrawn

Post-operative Corticosteroid Treatment After Mitral Valve Surgery (MitralPOCS)

Atrial Fibrillation

Finland
Smartfish AS

Completed

Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in COPD Cachexia

Cachexia | COPD

Sweden
Smartfish AS

Completed

Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in NSCLC Cachexia

NSCLC | Cachexia

Italy, Sweden, Croatia, Slovakia
ISU Abxis Co., Ltd.

Unknown

Exploratory P2 Trial to Evaluate Efficacy and Safety of Clotinab® (Abciximab) in Acute MI Patients

Acute Myocardial Infarction

Korea, Republic of
Gateway Institute for Brain Research

Recruiting

Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease (NOSE-PD)

Parkinson Disease

United States
Sinocelltech Ltd.

Unknown

SCT-I10A Plus Standard Chemotherapy in First-line Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

China
University of Aarhus

Completed

Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CT

Primary Biliary Cirrhosis

Denmark
Chinese PLA General Hospital

Unknown

Cell Therapy in Patients With Chronic Ischemic Heart Disease Undergoing Cardiac Surgery

Left Ventricular Dysfunction | Chronic Myocardial Ischemia | Old Myocardial Infarction

China
NextCell Pharma Ab

Completed

Wharton´s Jelly Derived Mesenchymal Stromal Cell Treatment of Adult Patients Diagnosed With Type I Diabetes

Type1 Diabetes Mellitus

Sweden
Shanghai University of Traditional Chinese Medicine
Fudan University; Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Chest... and other collaborators

Not yet recruiting

Clinical Study on the Prevention of Driver Gene Negative II-IIIa Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

Lung Cancer

China

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