Search clinical trials for: Placebo matched to VX-661

Total 1553 results

Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Efficacy of MK-7655 (Relebactam) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for Treating Complicated Urinary Tract Infection (cUTI) (MK-7655-003)

Urinary Tract Infections | Pyelonephritis
Merck Sharp & Dohme LLC

Completed

Study of Biomarkers of Airway Inflammation (0000-128)

Airway Inflammation
Liverpool Heart and Chest Hospital NHS Foundation...

Completed

Investigating the Incretin Effect in Cystic Fibrosis (IECF)

Cystic Fibrosis

United Kingdom
MEDRx USA, Inc.

Completed

Etodolac-Lidocaine Patch in the Treatment of Acute Low Back Pain

Low Back Pain

United States
Organon and Co

Completed

The Single Dose Pharmacokinetics of Two and Proof of Efficacy of One New Etoricoxib Gel Formulation in Participants With Osteoarthritis (MK-0663-168)

Osteoarthritis Pain
Orexigen Therapeutics, Inc

Completed

A Study Using Functional Magnetic Resonance Imaging (fMRI) to Assess the Effects of Naltrexone SR/ Bupropion SR Therapy in Overweight or Obese Subjects

Obesity

United States
Nanfang Hospital, Southern Medical University

Recruiting

Rapid Improvement of Depression of Fluoxetine Combined With ATP

Depression

China
MediciNova
Wake Forest University Health Sciences

Completed

Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS) (IBU-ALS-1201)

Amyotrophic Lateral Sclerosis

United States
Amgen

Terminated

Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid Arthritis

Juvenile Rheumatoid Arthritis
University of Southern California

Terminated

Romiplostim in Treating Hepatitis C-Infected Patients With Thrombocytopenia

Thrombocytopenia | Hepatitis C Infection

United States
Claire Daniels

Unknown

EoE RCT Fluticasone and Omeprazole vs Fluticasone Alone

Eosinophilic Esophagitis

United States
Merck Sharp & Dohme LLC

Completed

Aprepitant/MK0869 for Prevention of Chemotherapy Induced Nausea and Vomiting Associated With Cisplatin (0869-169)(COMPLETED)

Chemotherapy-induced Nausea and Vomiting (CINV)
University Hospital, Basel, Switzerland

Completed

Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study

Healthy | Substance-related Disorder | Mood Disorder

Switzerland
Pontificia Universidade Catolica de Sao Paulo

Completed

Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration

Fractures, Bone | Pruritus | Satisfaction, Personal | Nausea and Vomiting, Postoperative | Morphine Adverse Reaction

Brazil
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Completed

Dietary Supplement of Curcumin in Subjects With Active Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta 1a (CONTAIN)

Multiple Sclerosis

Italy
Mutual Pharmaceutical Company, Inc.

Completed

A Pharmacokinetic Study of Colchicine With an Oral Contraceptive

Pharmacokinetics

United States
University of Arizona

Completed

IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery

Lower Limb Injury

United States
Tiva Group

Completed

Morphine Consumption in the Obese Patients

Anesthesia Morbidity | Obesity, Morbid | Opioid Use | Post Operative Pain | Pharmacological Action

Spain
Tatyasaheb Kore Dental College

Completed

Analgesic Efficacy of Arnica Montana in Comparison With Diclofenac Sodium Following a Periodontal Surgical Procedure

Crown Lengthening Procedure With Ostectomy

India
Sunovion

Completed

Lurasidone Low-Dose - High-Dose Study Study

Schizophrenia

United States, Ukraine, Romania, Slovakia, Colombia, Russian Federation
Boehringer Ingelheim

Completed

Effectiveness of Two Different Doses of BI 1026706 on the Overall Peak-to-Peak (PtP) N2/P2-component Amplitude of Laser (Somatosensory, Radiant-heat) Evoked Potentials (LEP) in UVB(Ultraviolet)-Irradiated Skin in Healthy Male Volunteers

Healthy

Germany
Novartis
Merck Sharp & Dohme LLC

Completed

Bronchodilatory Efficacy of a Single Dose QMF149 (Indacaterol Maleate/Mometasone Furoate) Via the Twisthaler® Device in Adult Patients With Asthma

Asthma

France, Germany
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)

Urinary Bladder Neoplasms

United States, Australia, Czechia, Estonia, France, Guatemala, Hungary, Israel, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, Poland, Portugal, Puerto Rico, Romania, Spain, Taiwan, Turkey, Ukraine, United Kingdom, Denmark, ... and more
AO GENERIUM

Withdrawn

Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema

Hereditary Angioedema

Russian Federation
Creighton University
GlaxoSmithKline

Withdrawn

Adolescent and Adult Subjects With Asthma and Seasonal Allergic Rhinitis Receiving Advair Diskus or Placebo

Asthma | Seasonal Allergic Rhinitis

United States
Bayer

Completed

Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold

Common Cold | Tonsillitis | Pharyngitis

Ukraine, Russian Federation
VA Ann Arbor Healthcare System
University of Michigan

Completed

Ketamine Infusion for Comorbid PTSD and Chronic Pain

PTSD | Chronic Pain

United States
University Hospital, Basel, Switzerland

Completed

Influence of Bupropion on the Effects of MDMA

Healthy | Substance-related Disorders

Switzerland
Bristol-Myers Squibb

Completed

Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, United States, Argentina, Brazil, Canada, Mexico, Peru, Korea, Republic of, Sweden, Australia, Russian Federation, Poland, Puerto Rico, Czech Republic, Denmark, South Africa, Switzerland
Mark Ware

Terminated

Genetic Variants Associated With Low Back Pain and Their Response to Treatment With Duloxetine or Propranolol

Low Back Pain

Canada
Emory University

Completed

Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery (SITACABG NonDM)

Coronary Artery Disease

United States
Seoul National University Bundang Hospital
Yuhan Corporation

Completed

Study Design of 'Influence of Sarpogrelate in Patients With Renal Impairment or Diabetes Mellitus' Study (SERENADE)

Coronary Artery Disease | Diabetes Mellitus | Renal Insufficiency, Chronic

Korea, Republic of
McGill University Health Centre/Research Institute...

Terminated

Genetic Predictors of Analgesic Efficacy of Propranolol for Treating Postoperative Pain (PRO_GENE_POP)

Postoperative Pain

Canada
Merck Sharp & Dohme LLC

Terminated

Efficacy and Safety Study of Fosaprepitant (MK-0517) Plus Ondansetron Versus Ondansetron Alone for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Participants (MK-0517-044)

Chemotherapy-induced Nausea and Vomiting
Montefiore Medical Center

Completed

Orphenadrine and Methocarbamol for LBP

Low Back Pain

United States
Novartis

Completed

To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies

Type 2 Diabetes Mellitus | Impaired Glucose Tolerance

United States, Canada, Finland, Australia, Germany, India, Italy
University of Tennessee

Terminated

TAP Block With Liposomal Bupivacaine Versus Pre-incisional Wound Infiltration With Bupivacaine for Postoperative Pain (LATAP)

Postoperative Pain
Ain Shams University

Completed

Duloxetine and Dexamethasone for Improving Postoperative Pain

Post Operative Pain Control
Clark Stanford

Withdrawn

Case Series Evaluation of a Short Dental Implant (Short implant)

Tooth Loss

United States
Brian J Lipworth

Completed

Differential Adrenoreceptor Mediated Tachyphylaxis and Upregulation

Allergic Rhinitis | Tachyphylaxis | Rhinitis Medicamentosa

United Kingdom
King Khaled Eye Specialist Hospital

Completed

Late Onset Postoperative Nausea and Vomiting

Postoperative Nausea and Vomiting

Saudi Arabia
University of Oklahoma

Completed

Efficacy of Aprepitant (Emend®) in Children

Nausea | Vomiting | Childhood Cancer

United States
Merck Sharp & Dohme LLC

Completed

A Korean Study of Efficacy and Safety of Aprepitant-based Triple Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in the First Cycle of Moderately Emetogenic Chemotherapy (Non-doxorubicin Hydrochloride [Adriamycin] and Cyclophosphamide Regimens) (MK-0869-225) (KMEC) (KMEC)

Nausea | Vomiting
Association Asthma, Bulgaria
Nasaleze

Unknown

4"S" - Seasonal Symptoms Suppression Study (4"S")

Seasonal Allergic Rhinitis

Bulgaria
Eyegate Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution to Treat Non-Infectious Anterior Segment Uveitis

Anterior Uveitis

United States
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Gepotidacin

Infections, Bacterial

United States
The University of Texas Medical Branch, Galveston
National Institute of General Medical Sciences (NIGMS)

Completed

Assessment of Mechanisms of Improved Wound Healing

Burns

United States
Memorial Sloan Kettering Cancer Center

Completed

Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer

Rectal Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma

Childhood Diffuse Large Cell Lymphoma | Childhood Immunoblastic Large Cell Lymphoma | Childhood Burkitt Lymphoma | Untreated Childhood Acute Lymphoblastic Leukemia | Stage I Childhood Large Cell Lymphoma | Stage I Childhood Small Noncleaved Cell Lymphoma | Stage II Childhood Large Cell Lymphoma | Stage II Childhood Small Noncleaved Cell Lymphoma and other conditions

United States

Search clinical trials for: Placebo matched to VX-661

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