Search clinical trials for: Placebo matching MK-8189

Total 1525 results

Syneos Health
Chengdu Kanghua Biological products Co., Ltd.

Not yet recruiting

Evaluation of Recombinant Norovirus Hexavalent Vaccine in Healthy Subjects

Gastroenteritis
Bayer

Recruiting

A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies (ARASTEP)

Biochemically Recurrent Prostate Cancer

Austria, Spain, France, United States, Australia, Brazil, Germany, Taiwan, Denmark, China, Netherlands, Japan, Canada, Finland, Italy, Hungary, Portugal, United Kingdom, Poland, Israel, New Zealand, Sweden, Belgium, Czechia
Ironwood Pharmaceuticals, Inc.

Completed

A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States
AstraZeneca

Completed

MEDI7183 Phase 2 Study in Japanese Ulcerative Colitis Patients

Ulcerative Colitis

Japan
Organon and Co

Completed

Study of MK-0663/Etoricoxib in Postorthopedic Knee Replacement Surgery Pain (MK-0663-098)

Pain, Postoperative
ALK-Abelló A/S

Completed

A Study of Ragweed (Ambrosia Artemisiifolia) Allergy Immunotherapy Tablet in Adults With Ragweed Allergies (P05751)

Allergy
Boehringer Ingelheim

Recruiting

A Study to Test How Well Different Doses of BI 3006337 Are Tolerated by People With Overweight or Obesity and With Fatty Liver Disease

Obesity | Non-alcoholic Fatty Liver Disease

United States
Berlin Cures GmbH

Active, not recruiting

To Investigate Efficacy, Pharmacodynamics, and Safety of BC 007 in Participants With Long COVID (BLOC)

Long Covid

Germany, Austria, Finland, Spain, Switzerland
Pfizer

Completed

Acute Treatment Trial in Adult Subjects With Migraines

Migraine

United States
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

Korea, Republic of, United States, Brazil, Japan, Spain, Argentina, Hungary, Poland, United Kingdom, Australia, Taiwan, Canada, Germany
Bristol-Myers Squibb

Completed

Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa, United States, Canada, Puerto Rico, Hungary, Germany, Czechia, Poland, Romania, United Kingdom
Yuhan Corporation

Active, not recruiting

Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301)

Non-Small Cell Lung Cancer

Hungary, Korea, Republic of, Australia, Taiwan, Serbia, Singapore, Thailand, Philippines, Turkey, Malaysia, Russian Federation, Greece, Ukraine
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

Evaluation of 611(Recombinant Humanized Anti-interleukin-4 Receptor Alpha IgG4 Monoclonal Antibody) in Chinese Adults With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

China
Bristol-Myers Squibb

Terminated

A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-963272 in Participants With Nonalcoholic Fatty Liver Disease

Nonalcoholic Fatty Liver Disease

United States
Novartis
Integrium; Great Lakes Drug Development, Inc.

Completed

A Study to Evaluate the Effects of LCI699 on Cortisol in Participants With Hypertension

Hypertension

United States, Iceland
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

A FIH Study to Investigate the Safety, Tolerability and PK of P218

Malaria

United Kingdom
Bristol-Myers Squibb

Withdrawn

Proof of Concept Study of BMS-823778 to Assess the Effects on Atherosclerosis

Atherosclerotic Cardiovascular Disease
Merck Sharp & Dohme LLC

Completed

Single Ascending Dose Study of MK-1092 in Healthy Participants and in Participants With Type 1 and Type 2 Diabetes Mellitus (MK-1092-001)

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

United States
Novartis Pharmaceuticals

Active, not recruiting

Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. (V-Mono)

Hypercholesterolemia

United States, Germany, Hungary, Colombia, Mexico
Inmune Bio, Inc.

Withdrawn

Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurodegenerative Diseases | Dementia | Mild Cognitive Impairment (MCI) | Alzheimer Disease | Tauopathies
Mallinckrodt

Completed

Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1

Hepatorenal Syndrome

United States, Canada
Daiichi Sankyo, Inc.

Withdrawn

DS-9231 in Intermediate-risk (Sub-massive) Acute Pulmonary Embolism (PE)

Pulmonary Embolism
Merck Sharp & Dohme LLC

Terminated

Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression (TRD) (MK-1942-006)

Treatment Resistant Depression

United States
Kallyope Inc.

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes

Obesity | Type 2 Diabetes Mellitus (T2DM)

United States
Eli Lilly and Company

Completed

A Study of LY2216684 in Healthy Participants

Major Depressive Disorder

United States
AstraZeneca

Recruiting

Zibotentan and Dapagliflozin Combination, EvAluated in Liver Cirrhosis (ZEAL Study) (ZEAL)

Liver Cirrhosis

Denmark, Spain, Germany, United States, France, Australia, China, Netherlands, Belgium, Switzerland, Austria, United Kingdom, Taiwan, Canada, Czechia
Regeneron Pharmaceuticals
Sanofi

Completed

Dupilumab As An Adjunct For Subcutaneous Grass Immunotherapy

Allergic Rhinitis

United States, Canada
Rajesh Kumar
University of Colorado, Denver; National Institute of Allergy and Infectious... and other collaborators

Recruiting

Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study (SIRA)

Asthma in Children | Wheezing

United States
Zambon SpA

Completed

Effect of Safinamide on Parkinson's Disease Related Chronic Pain

Idiopathic Parkinson Disease

Spain, Austria, Italy, Germany, France
Mayo Clinic

Completed

Metformin for the Prevention of Episodic Migraine (MPEM) (MPEM)

Migraine

United States
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of MK-0616 (Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017) CORALreef HeFH

Hypercholesterolemia | Familial Hypercholesterolemia

United States, Australia, Brazil, Canada, Chile, Colombia, Czechia, Finland, Hong Kong, Hungary, Israel, Netherlands, New Zealand, Norway, Singapore, Spain, Taiwan
Merck Sharp & Dohme LLC

Completed

A Dose Finding Study of Preladenant (SCH 420814) for the Treatment of Parkinson's Disease (PD) in Japanese Patients (P06402)

Parkinson's Disease
Merck Sharp & Dohme LLC

Terminated

Safety and Efficacy of MK-6096 as Adjunctive Therapy in Participants With Major Depressive Disorder And Partial Response to Antidepressant Monotherapy (MK-6096-022)

Major Depressive Disorder, Recurrent
University of Pittsburgh
Merck Sharp & Dohme LLC

Completed

Gamma-Amino Butyric Acid (GABA)-A Alpha2/3 Study

Schizophrenia

United States
The Deutsche Diabetes Forschungsgesellschaft e.V.
Algiax Pharmaceuticals GmbH

Recruiting

Effects of GABAA Receptor Modulation by AP-325 on Insulin Secretion in Patients With Type 2 Diabetes

Type2 Diabetes

Germany
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI); Duke University; National...

Recruiting

Supplementing L-citrulline to Overweight Late Asthma oNset Phenotypes (SANDIA)

Obesity | Asthma

United States
Regulus Therapeutics Inc.

Completed

A Study of RGLS8429 in Healthy Volunteers

Healthy Volunteers

United States
CSL Behring

Completed

Psoriatic Arthritis Dose Ranging Study for BMS-945429 in Subjects Who Are Not Responding to NSAIDs or Non-biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) Therapy

Arthritis, Psoriatic

Italy, United States, Canada, Mexico, Poland, Spain, Germany, Czechia, Russian Federation, Australia, South Africa, Argentina, Hungary
The University of Hong Kong

Active, not recruiting

A Study to Evaluate Safety and Immunogenicity of DelNS1-nCoV-RBD LAIV for COVID-19

Covid19

Hong Kong
Emerald Health Pharmaceuticals

Completed

To Evaluate the Safety and Tolerability, Pharmacokinetics, Food-effect and Pharmacodynamics of EHP-101 in Healthy Volunteers

Healthy

Australia
Vertex Pharmaceuticals Incorporated

Completed

A Magnetic Resonance Imaging Study and Arthroscopic Biopsy Substudy in Subjects With Active Rheumatoid Arthritis Receiving VX-509, an Oral JAK3 Inhibitor

Rheumatoid Arthritis

United States, Denmark, Estonia, Lithuania, Netherlands, South Africa
Molecular Research Center, Inc.
Harrison Clinical Research; Camargo Pharmaceutical Services; Clin Data Services; BARC Global Central Laboratory and other collaborators

Unknown

A Study of Two Doses of MRC375 in Moderate to Severe Rheumatoid Arthritis Patients

Rheumatoid Arthritis

United States
Zynerba Pharmaceuticals, Inc.

Completed

Clinical Study Of caNNabidiol in childrEn and adolesCenTs With Fragile X (CONNECT-FX) (CONNECT-FX)

Fragile X Syndrome

United States, New Zealand, Australia
Merit E. Cudkowicz, MD
Calico Life Sciences LLC

Enrolling by invitation

HEALEY ALS Platform Trial - Regimen F ABBV-CLS-7262

Amyotrophic Lateral Sclerosis

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 When Administered Concomitantly With Influenza Vaccine in Adults 50 Years of Age or Older (V116-005, STRIDE-5)

Pneumonia, Pneumococcal

United States
GlaxoSmithKline

Terminated

Efficacy and Safety Study of Mepolizumab in Subjects With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

United States, Canada
Vaxart

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Topical Applications of AP611074 5% Gel for up to 16 Weeks in Condyloma Patients

Condyloma

Argentina, Chile, Ecuador, Serbia
GlaxoSmithKline

Completed

A Study of GSK573719 in Healthy Japanese Male Subjects

Pulmonary Disease, Chronic Obstructive

Japan
Respivert Ltd

Completed

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Repeat Doses of RV1729 for 28 Days in Patients With COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Boehringer Ingelheim

Recruiting

A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Netherton Syndrome

Netherton Syndrome

Belgium, United Kingdom, Australia, Germany, China, Malaysia, United States, Japan, France, Israel, Bulgaria, Italy, Finland, Switzerland, Netherlands, Portugal

Search clinical trials for: Placebo matching MK-8189

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