Search clinical trials for: Placebo matching to spesolimab - solution for infusion

Total 943 results

University of Texas Southwestern Medical Center
National Institute on Drug Abuse (NIDA)

Recruiting

Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2) (CURB-2)

Cocaine Use Disorder

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Efficacy and Safety of Sitagliptin and MK0431A in Comparison to a Commonly Used Medication in Patients With Type 2 Diabetes (0431-068)(COMPLETED)

Type 2 Diabetes Mellitus
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease (CPIFGD)

Irritable Bowel Syndrome | Probiotics | Colonoscopy | Functional Constipation

China
Hoffmann-La Roche

Completed

A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-angle

United States
Navy General Hospital, Beijing
Xijing Hospital; Peking Union Medical College Hospital; Chinese PLA General Hospital and other collaborators

Unknown

WJMSCs Anti-inflammatory Therapy in Coronary Artery Disease (WANICHD)

Coronary Artery Disease
University Hospital, Grenoble
Becton, Dickinson and Company

Completed

Carbapenemase-Producing Organism and Vancomycin-Resistant Enterococcus Management (CPO-VRE)

Multidrug-resistant Bacteria Screening

France
Bristol-Myers Squibb

Completed

A Two-Part, Phase 1, Single-Dose Study of IL-31 mAb (Anti-Interleukin 31 Monoclonal Antibody); in Healthy Subjects and Adults With Atopic Dermatitis

Healthy Subjects and Atopic Dermatitis Subjects

United Kingdom
Emerald Health Pharmaceuticals

Suspended

Evaluation of Safety, Tolerability and Preliminary Efficacy of EHP-101 in Diffuse Cutaneous Systemic Sclerosis

Diffuse Cutaneous Systemic Sclerosis

United States, Puerto Rico, Australia, New Zealand
Rebiotix Inc.

Completed

Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD3)

Clostridium Difficile Infection (CDI)

United States, Canada
Hospices Civils de Lyon

Completed

Cystic Fibrosis Related Diabetes Screening. (D2M)

Cystic Fibrosis-related Diabetes
UCB Pharma

Completed

A Study to Compare the Efficacy of Levocetirizine to Placebo in Reducing Symptoms of Seasonal Allergic Rhinitis (SAR) in Sensitive Subjects Exposed to Ragweed Pollen

Rhinitis | Allergic | Seasonal

Canada
AUVA Traumazentrum Vienna Site UKH Meidling
CCSRM Clinical Center for Studies in Regenerative Medicine in cooperation... and other collaborators

Recruiting

Influence of an Anti-osteoporotic Drug on Healing After Surgical Repair of Chronic Rotator Cuff Lesions of the Shoulder (ZORRO)

Traumatology | Orthopedics

Austria
Chiesi Canada Corp

Completed

Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children (START)

Iron Overload | Beta Thalassemia Major Anemia

Egypt, Indonesia
University Hospital Heidelberg

Unknown

A Randomized Trial Comparing 2 Methods for Rapid Induction of Cooling in Stroke Patients, Cold Infusions vs. EMCOOLS Flex.Pads (iCOOL 2) (iCOOL 2)

Ischemic Stroke | Hemorrhagic Stroke

Germany
Ocera Therapeutics, Inc.

Completed

Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE) (STOP-HE)

Hepatic Encephalopathy | Acute Episode of Overt Hepatic Encephalopathy

Belgium, Germany, Italy, Spain, United States, France, Austria, Russian Federation, Czechia, Australia, Hungary, Israel, Netherlands, Bulgaria, Estonia, Denmark, New Zealand
Assembly Biosciences

Completed

A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy Adults

Chronic Hepatitis B

New Zealand
Menarini Group

Withdrawn

Preliminary Efficacy and Safety Study of Oral Nepadutant in Infant With Colic Not Responding to Conventional Treatment (nocry-a)

Infantile Colic
Xijing Hospital of Digestive Diseases

Unknown

Mesenchymal Stem Cell Transplantation for Refractory Primary Biliary Cholangitis

Primary Biliary Cirrhosis

China
Colorado State University

Completed

Cannabidiol Effects on Blood Alcohol Level and Intoxication

Alcohol Use Disorder

United States
AstraZeneca

Terminated

A Study of Benralizumab in Patients With Eosinophilic Esophagitis (MESSINA)

Eosinophilic Esophagitis

United States, Italy, Spain, Canada, Poland, Germany, Japan, Netherlands, France, Israel, Russian Federation, United Kingdom
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects

Cardiovascular Disease

United Kingdom
9305-9954 Quebec Inc

Unknown

The Efficacy of CELEXT07 in the Treatment of Toenail Onychomycosis

Onychomycosis

Canada
ACELYRIN Inc.

Completed

Hidradenitis Suppurativa Phase 2b Pivotal Study of Izokibep

Hidradenitis Suppurativa

United States, Canada, Germany, Hungary, Poland, Spain
Theratocular Biotek Co.
Novotech (Australia) Pty Limited

Active, not recruiting

A Study to Investigate the Effect of IOP-lowering With TO-O-1001 Eye Drops in Healthy Subjects and in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

Australia
AstraZeneca

Completed

Esophageal Hypersensitivity Study in Patients With Gastroesophageal Reflux Disease (GERD)

Sensitivity in Esophagus

Denmark, Sweden
Pulmatrix Inc.

Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of PUR3100 in Health Adults

Healthy

Australia
ACELYRIN Inc.

Active, not recruiting

Psoriatic Arthritis Study of Izokibep

Psoriatic Arthritis

United States, Bulgaria, Canada, Czechia, Germany, Hungary, Poland, Spain
AstraZeneca

Completed

Study to Investigate Multiple Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects

Healthy

United States
AstraZeneca

Terminated

A First Time in Man Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD1979 in Healthy Males

Healthy Subjects

United States
Clinical Institute of the Brain, Russia

Unknown

Comprehensive Reparative Therapy in Ischemic Stroke COMplex Repair in Ischemic Stroke-Arm

Ischemic Stroke

Russian Federation
Menarini Group

Completed

Preliminary Efficacy and Safety Study of Oral Nepadutant in Infant Colic (no-cry)

Infantile Colic

Russian Federation, Germany, Poland, Sweden
Afferent Pharmaceuticals, Inc.

Completed

A 12-Week Study in Participants With Refractory Chronic Cough (MK-7264-012)

Refractory Chronic Cough
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-777991 in Healthy Subjects

Healthy

Netherlands
GlaxoSmithKline

Completed

Absorption and Elimination of Radiolabeled Daprodustat

Anaemia

United Kingdom
Takeda

Completed

Efficacy and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-like Particle Vaccine in Adults

Healthy Volunteers

United States
UCB Biopharma S.P.R.L.

Completed

A Study to Investigate the Bioequivalence of Lacosamide 200mg Administered as Intravenous Solution and Oral Tablet in Healthy Chinese Male Subjects

Healthy Male Chinese Volunteers

China
Eicos Sciences, Inc.

Completed

Intravenous Iloprost in Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis (Phase 2)

Raynaud Phenomenon Secondary to Systemic Sclerosis

United States
Samsung Medical Center

Completed

Efficacy of Motilitone on Gastric Accommodation in Healthy Adult Patients: Evaluation Using MRI Method

Dyspepsia

Korea, Republic of
Alfonso Gomez-Iturriaga
Hospital de Cruces

Unknown

Dose Escalation to Dominant Intraprostatic Lesions (DIL) With MRI-TRUS Fusion High Dose Rate (HDR) Prostate Brachytherapy (BRAPROST)

Prostate Cancer

Spain
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (ATLAS)

Nonalcoholic Steatohepatitis

Hong Kong, United States, Australia, Puerto Rico, New Zealand, Canada
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Therapy (MK-3102-024)

Type 2 Diabetes Mellitus
Maastricht University Medical Center
Top Institute Food and Nutrition

Completed

Short Chain Fatty Acid Metabolism and Energy Metabolism

Obesity | Type 2 Diabetes Mellitus

Netherlands
AstraZeneca

Active, not recruiting

Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab. (MANDARA)

Eosinophilic Granulomatous Vasculitis

United States, Canada, France, Italy, Israel, United Kingdom, Japan, Germany, Belgium
CHA University
Merck Sharp & Dohme LLC

Completed

Response of FeNO, Small Airway Dysfunction and Lung Heterogeneity to 2-week Montelukast Treatment in Asthmatic Children.

Mild Persistent Asthma
Janssen Research & Development, LLC

Completed

Effects of Co-administration of Canagliflozin 300 mg and Phentermine 15 mg With Placebo in the Treatment of Non-Diabetic Overweight and Obese Participants

Obesity

United States
Optimer Pharmaceuticals LLC

Completed

Fidaxomicin Versus Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD) (MK-5119-018)

Diarrhea | Clostridium Infections
Federal Budgetary Research Institution State Research...

Completed

Study of the Tolerability, Safety, Immunogenicity and Preventive Efficacy of the EpiVacCorona Vaccine for the Prevention of COVID-19

COVID-19

Russian Federation
Montefiore Medical Center
Novartis Pharmaceuticals

Withdrawn

Pasireotide in Hyperinsulinemic Hypoglycemia

Hyperinsulinism | Insulinoma | Congenital Hyperinsulinism
Zynerba Pharmaceuticals, Inc.

Recruiting

Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome (RECONNECT)

Fragile X Syndrome

United States, Australia, United Kingdom, Ireland
Fundación Pública Andaluza para la gestión de la...
Spanish Network for Research in Infectious Diseases

Completed

Fosfomycin Versus Meropenem or Ceftriaxone in Bacteriemic Infections Caused by Multidrug Resistance in E.Coli (FOREST)

Infection Due to ESBL Escherichia Coli

Spain

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