Search clinical trials for: Placebo multiple ascending doses

Total 1665 results

University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
Hospital Regional Dr. Rafael Estévez
Complejo Hospitalario Dr. Arnulfo Arias Madrid; Hospital Santo Tomas; Hospital... and other collaborators

Completed

Use of Multiple Doses of Convalescent Plasma in Mechanically Intubated Patients With COVID-19

COVID-19

Panama
Xi'an Xintong Pharmaceutical Research Co.,Ltd.

Unknown

A Study to Investigate the Safety, Tolerability, Pharmacokinetics of Single and Multiple Doses of Hepenofovir Fumarate Tablets in Healthy Volunteers.

Chronic Hepatitis b
Afyonkarahisar Health Sciences University

Completed

The Efficacy of PRP Injection in the Treatment of Rotator Cuff Syndrome (PRP)

Musculoskeletal Diseases | Shoulder Pain | Rotator Cuff Tendinopathy | Rotator Cuff Syndrome

Turkey
Arcturus Therapeutics, Inc.

Terminated

A Trial Evaluating the Safety and Effects of an RNA Vaccine ARCT-021 in Healthy Adults

Covid19 | Corona Virus Infection | SARS-CoV Infection

United States, Singapore
ReAlta Life Sciences, Inc.
FGK Clinical Research GmbH

Completed

A Clinical Study to Determine the Safety, Tolerability and Effect of RLS-0071 Doses When Given to Healthy Adults After Inhaling LPS

Healthy

Germany
Innovaderm Research Inc.
Schering-Plough

Completed

Safety and Efficacy of Infliximab in Palmoplantar Psoriasis

Palmoplantar Psoriasis

Canada
Apnimed

Completed

AD109 Dose Finding in Mild to Moderate OSA

Obstructive Sleep Apnea

United States
Beijing Peking University WBL Biotech Co., Ltd.

Completed

Efficacy and Safety Study of Lipid-Lowering Effects of XueZhiKang (XZK) in Patients With Hyperlipidemia

Hyperlipidemia

China, United States
Cellectar Biosciences, Inc.

Recruiting

Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom Macroglobulinemia (CLOVER-WaM)

Multiple Myeloma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | Central Nervous System Lymphoma

United States, Australia, Czechia, Greece, Israel, Brazil, Finland, France, Spain, Turkey, United Kingdom
Guohua Zeng

Unknown

Comparison of Multiple-, Single- and Zero-dose of Ciprofloxacin Prophylaxis in Retrograde Intrarenal Surgery (RIRS)

Kidney Stones

China
Jiangsu Province Centers for Disease Control and...
Academy of Military Medical Sciences，Academy of Military Sciences，PLA; ZHONGYIANKE... and other collaborators

Recruiting

Phase I Trial of a Recombinant COVID-19 Vaccine (CHO Cell)

COVID-19

China
Vedanta Biosciences, Inc.

Recruiting

VE202 in Patients With Mild-to-Moderate Ulcerative Colitis

Ulcerative Colitis | Colitis, Ulcerative

United States, Netherlands, Lithuania, Bulgaria, Hungary, Ukraine, Czechia, Poland, United Kingdom
Chi Mei Medical Hospital
GeneFerm Biotechnology Co., Ltd.

Completed

Efficacy and Safety of Geneferm Nattokinase

Hyperlipidemia

Taiwan
Jiangsu Province Centers for Disease Control and...
West China Hospital

Completed

Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)

COVID-19

China
Jiangsu Province Centers for Disease Control and...
Beijing Institute of Biotechnology; Tianjin Cansino Biotechnology Inc

Completed

A Phase I Clinical Trial to Evaluate the Ebola Adenovirus Vector Vaccine (Ad5-EBOV) in Healthy Adults.

Ebola Virus Disease

China
Noah Merin
Johns Hopkins University

Terminated

Convalescent Plasma in ICU Patients With COVID-19-induced Respiratory Failure

Covid-19 | Sars-CoV2

United States
Estetra

Completed

Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers

Menopause | Contraception

Bulgaria
Pulmocide Ltd

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of PC945

Aspergillosis

United Kingdom
Asan Medical Center
JW Pharmaceutical

Completed

Drug Interaction and Safety Between Pitavastatin and Valsartan (CWP-PTV-101)

Healthy

Korea, Republic of
University of Minnesota
Joint Clinical Research Center

Completed

Optimizing Iron Status While Minimizing Morbidity in HIV-infected Ugandan Children

Iron-deficiency | Anemia | Hiv | Iron Deficiency Anemia

Uganda
Eli Lilly and Company

Completed

A Device Study in Healthy Participants

Healthy

United Kingdom
Institute for Clinical and Experimental Medicine

Recruiting

INSULIN THERAPY DE-INTENSIFICATION WITH iGlarLixi (IDEAL)

Type 2 Diabetes Treated With Insulin

Czechia
Oasis Pharmaceuticals, LLC
Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases...

Recruiting

Safety Study of OA-235i in Subjects With Nonalcoholic Steatohepatitis

Nonalcoholic Steatohepatitis | Nonalcoholic Fatty Liver

United States
Labopharm Inc.

Completed

A Comparative Bioavailability/Food Effect Study of Immediate-Release and Extended-Release Tramadol HCl/Acetaminophen Combination Products Following Single-Dose and Multiple-Dose Administration in Healthy Adult Volunteers

Healthy

United Kingdom
Pfizer
AbbVie

Not yet recruiting

A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH) (CHERISH)

Gram-negative Bacterial Infection
NEURALIS s.a.

Recruiting

Single and Multiple Intravenous Administrations of Estetrol (E4) in Healthy Adult Volunteers

Pharmacokinetics | Safety

Bulgaria
Human Genome Sciences Inc.
GlaxoSmithKline

Completed

Study of Belimumab Administered Subcutaneously to Healthy Subjects

Healthy

United States
Beijing Tongren Hospital

Recruiting

The Phase I Study of Recombinant Human Nerve Growth Factor Injection

Injury of Optic Nerve

China
Novo Nordisk A/S

Recruiting

A Research Study to See How Well Semaglutide Helps People Who Have a Body Weight Above the Healthy Weight Range (STEP12)

Obesity | Overweight

China, Taiwan
University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
Hoffmann-La Roche

Completed

A Study of Tarceva (Erlotinib) Following Platinum-Based Chemotherapy in Patients With Advanced, Recurrent, or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer

Australia, China, Korea, Republic of, Denmark, Germany, Greece, Russian Federation, Hungary, France, Netherlands, New Zealand, Spain, Austria, Slovakia, United Kingdom, Malaysia, Belgium, Lithuania, South Africa, Slovenia, Italy, ... and more
University of Manitoba
The Hospital for Sick Children; University of British Columbia; McGill University

Enrolling by invitation

Predictors of Persistent Peanut Allergy at Age 5 Years

Allergy to Peanut
Shahid Beheshti University of Medical Sciences
Ophthalmic Research Center

Unknown

Evaluation of Omeprazole Effect on Glaucoma

Glaucoma

Iran, Islamic Republic of
Abu Dhabi Stem Cells Center

Recruiting

Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Type 1 Diabetes Mellitus (OPERA)

Type 1 Diabetes

United Arab Emirates
XOMA (US) LLC

Completed

An Open-Label Study of XOMA 358 in Patients With Hypoglycemia After Gastric Bypass Surgery (XOMA 358)

Hypoglycemia

United States
Ain Shams University

Completed

Long Acting Insulin Versus Multiple Dose Regimen for Control of Gestational Diabetes Mellitus

Long Acting Insulin in Control of Gestational Diabetes Mellitus

Egypt
HK inno.N Corporation

Unknown

A Study to Explore Pharmacokinetics/Pharmacodynamics and Safety of Tegoprazan BID Dosing in Healthy Subjects

Healthy

Korea, Republic of
Stanford University

Completed

Gastric Acid Suppression and Probiotic Colonization (PR)

Probiotics

United States
Yiling Pharmaceutical Inc.

Completed

A Phase I Pharmacokinetics Study for KT07 Capsule

Pharmacokinetics | Healthy Adult Subjects | Safety and Tolerability

United States
MedImmune LLC

Completed

A Study to Evaluate Safety and Pharmacodynamic Efficacy of 0382 in Obese Subjects With NAFLD/NASH.

Non-alcoholic Fatty Liver Disease (NAFLD) | Non-alcoholic Steatohepatitis (NASH)

United States, Puerto Rico
Pulmocide Ltd

Completed

A Study to Investigate the Safety and Tolerability of Single and Repeat Doses of PC786

Respiratory Syncytial Virus (RSV)

United Kingdom
Livzon Pharmaceutical Group Inc.

Completed

A Multi-center, Double-blinding, Parallel and Positive-controlled Phase III Clinical Trial for Efficacy and Safety Evaluation of Ilaprazole Sodium for Injection on Prevention of Stress Ulcer Bleeding

Stress Ulcer Bleeding

China
Merck Sharp & Dohme LLC

Completed

A Study of Intradermal Administration of ZOSTAVAX™ (V211-051 AM2)

Herpes Zoster
Aboca Spa Societa' Agricola
University of Roma La Sapienza; Doppel Farmaceutici; BMR Genomics

Completed

Efficacy and Safety Evaluation of Neobianacid® in GERD and EPS

GERD | EPS

Italy
AstraZeneca

Completed

Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®) (ECLIPSEIII)

Hypertriglyceridemia

United States
Eunice Kennedy Shriver National Institute of Child...

Terminated

Free Fatty Acids, Body Weight, and Growth Hormones Secretion in Children

Obesity | Growth Hormone Deficiency | Short Stature

United States
Jiangsu Kanion Pharmaceutical Co., Ltd

Completed

Effect of KYG0395 on Primary Dysmenorrhea

Primary Dysmenorrhea

United States
Respivert Ltd

Completed

A Study to Investigate the Safety and Tolerability of a New Inhaled Formulation of RV568 in Healthy Volunteers

Healthy Volunteers | COPD

United Kingdom
Indonesia University
Medika Natura Sdn Bhd

Completed

Dose-ranging Study of SKF7™ for Obesity

Obesity

Indonesia

Search clinical trials for: Placebo multiple ascending doses

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