- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01000220
Evaluation of Omeprazole Effect on Glaucoma
May 3, 2010 updated by: Shahid Beheshti University of Medical Sciences
Omeprazole is a safe drug listed in OTC drug due to its safety.
It acts by irreversible inhibition of K/H ATP ase pump and also Na/K ATP ase, Na/H ATP ase.Considering these actions the effect of omeprazole on decreasing intra ocular pressure is an issue of debate.In this Randomized Clinical Trial conducted in labafinejad hospital, patients with glaucoma who need to take omeprazole due to GI problem are evaluated in two groups including placebo and drug users.
The effect will be finally assessed.
Study Overview
Detailed Description
Omeprazole is a safe drug listed in OTC drug due to its safety.
It acts by irreversible inhibition of K/H ATP ase pump and also Na/K ATP ase, Na/H ATP ase.Considering these actions the effect of omeprazole on decreasing intra ocular pressure is an issue of debate.In this Randomized Clinical Trial conducted in labafinejad hospital, patients with glaucoma who need to take omeprazole due to GI problem are evaluated in two groups including placebo and drug users.
The effect will be finally assessed.
Study Type
Interventional
Phase
- Phase 1
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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-
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Tehran, Iran, Islamic Republic of, 166666
- Recruiting
- Ophthalmic Research Center
-
Contact:
- Shahin yazdani, MD
- Phone Number: +98 21 22585952
- Email: labbafi@hotmail.com
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 70 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- patients with glaucoma
- 18 to 70 years
- POAG patients, Pseudoexfoliation
- no history of other systemic disease
- no history of intraocular intervention
- no history of H2 blocker or PPI consumption during the past month consuming 2 or less topical anti-glaucoma medication
- no present immune deficiency
- no addiction habit
Exclusion Criteria:
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Placebo Comparator: placebo
|
|
Active Comparator: Omeprazole
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
July 7, 2009
First Submitted That Met QC Criteria
October 21, 2009
First Posted (Estimate)
October 22, 2009
Study Record Updates
Last Update Posted (Estimate)
May 4, 2010
Last Update Submitted That Met QC Criteria
May 3, 2010
Last Verified
October 1, 2009
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 8735 (CTEP)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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