Search clinical trials for: placebo to tocilizumab

Total 61221 results

Reata, a wholly owned subsidiary of Biogen
AbbVie; Friedreich's Ataxia Research Alliance

Active, not recruiting

RTA 408 Capsules in Patients With Friedreich's Ataxia - MOXIe

Friedreich Ataxia

United States, Australia, Austria, Italy, United Kingdom
Organon and Co
Novartis

Completed

Effects of Mometasone Furoate/Formoterol Combination Versus Mometasone Furoate Alone in Persistent Asthmatics (Study P04073AM1)(COMPLETED)

Asthma
King's College London
Wellcome Trust; The Royal Society

Completed

Investigating the Role of Diazepam on Brain Function and Chemistry in Psychosis Risk (BENZOGAP)

Prodromal Schizophrenia

United Kingdom
Amgen

Completed

Efficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis. (FOREMOST)

Arthritis, Psoriatic

United States, Spain, Netherlands, Canada, France, Russian Federation, Belgium, Austria, Germany, Italy, United Kingdom
Food and Drug Administration (FDA)
Leiden University; Spaulding Clinical Research LLC

Completed

Effect of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on Ventilation

Hypercapnia | Ventilatory Depression

United States
Sanofi Pasteur, a Sanofi Company

Active, not recruiting

Study of Monovalent and Bivalent Recombinant Protein Vaccines Against COVID-19 in Adults 18 Years of Age and Older (VAT00008)

COVID-19

United States, Colombia, Ghana, Honduras, India, Japan, Kenya, Mexico, Nepal, Nigeria, Sri Lanka, Uganda, Ukraine
Klinički Bolnički Centar Zagreb
University of Zagreb

Completed

PCME Prevention in Patients With NPDR

Cystoid Macular Edema Following Cataract Surgery

Croatia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery

Colorectal Cancer

United States, Canada, Puerto Rico
Alfarabi Colleges

Completed

Effectiveness of Premedication on the Success Rate of Inferior Alveolar Nerve Block

Symptomatic Irreversible Pulpitis

Saudi Arabia
University of Florida
National Institute on Aging (NIA)

Withdrawn

Inflammation Control For Elders: ICE Study (ICE)

Inflammation | Aging
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

United States, Australia, Bulgaria, Romania, India, Slovakia, Philippines
Actavis Inc.
Teva Pharmaceuticals USA

Completed

Therapeutic Equivalence of Two Formulations of Fluticasone Propionate and Salmeterol Inhalation Powder in Subjects With Asthma

Asthma

United States
German Breast Group
AstraZeneca; Celgene

Completed

Addition of PD-L1 Antibody MEDI4736 to a Taxane-anthracycline Chemotherapy in Triple Negative Breast Cancer (GeparNuevo)

Breast Cancer

Germany
LEO Pharma

Completed

Clinical Trial to Assess Safety, Tolerability and the Pharmacodynamics Effect of Calcipotriol/Betamethasone Dipropionate in a New Administration Form in Subjects With Chronic Plaque Psoriasis.

Psoriasis Vulgaris

Germany
Hospital de Granollers

Completed

Effect of Serotonin and Levodopa in Ischemic Stroke (SELEIS)

Stroke

Spain
Brian J Lipworth

Completed

Differential Trough Effects of 'Triple Therapy' on Pulmonary Function in Chronic Obstructive Pulmonary Disease (COPD) (FARD12)

COPD

United Kingdom
Indiana University
National Institute of Mental Health (NIMH)

Completed

Evaluating the Effectiveness of Aripiprazole and D-Cycloserine to Treat Symptoms Associated With Autism

Autistic Disorder

United States
The Cleveland Clinic

Terminated

Lidocaine and Ketamine Versus Standard Care on Acute and Chronic Pain

Pain | Nausea

United States
Cairo University

Unknown

Intraperitoneal Dexamethasone vs Dexamethasone Plus Magnesium Sulphate for Pain Relief in Laparoscopic Cholecystectomy

Pain, Postoperative

Egypt
Ghada Mohammed AboelFadl

Completed

Oral Amantadine Versus Gabapentin to Attenuate the Response to Laryngoscopy and Tracheal Intubation (15/5/2017)

Effect of Laryngoscopy and Tracheal Intubation

Egypt
Zhejiang University
Shanghai CP Guojian Pharmaceutical Co., Ltd.

Completed

Optimizing Psoriasis Treatment of Etanercept Combined Methotrexate

Psoriasis

China
Wonkwang University Hospital

Completed

Combination Effects of Pregabalin and Dexmedetomidine on Postoperative Pain

Pain, Postoperative

Korea, Republic of
GlaxoSmithKline

Completed

Study Evaluating the 24-Hour Pulmonary Function Profile of Fluticasone Furoate (FF) /GW642444 (Vilanterol) (VI) Inhalation Powder 100/25mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States, Germany, Ukraine, Spain, South Africa, Italy
Faculdade de Ciências Médicas da Santa Casa de...

Unknown

Prophylaxy of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Surgery

Postoperative Complications | Postoperative Nausea and Vomiting

Brazil
Baim Institute for Clinical Research
Bristol-Myers Squibb; Eli Lilly and Company; Daiichi Sankyo, Inc.; Boston Scientific... and other collaborators

Completed

The Dual Antiplatelet Therapy Study (DAPT Study)

Coronary Artery Disease

United States, Australia, Czechia, New Zealand, United Kingdom, Germany, Hungary, Poland, France, Romania
University of Pennsylvania
National Institute of Mental Health (NIMH)

Completed

Effectiveness of Long-Term Versus Short-Term Treatment of Generalized Anxiety Disorder With Venlafaxine XR

Anxiety Disorders

United States
St George's, University of London
Rosetrees Trust

Completed

Pain Management in Osteoarthritis Using the Centrally Acting Analgesics Duloxetine and Pregabalin (DUPRO)

Hand Osteoarthritis

United Kingdom
University of Miami
GlaxoSmithKline

Completed

Interactive Acute Smooth Muscle Effects of Salmeterol and Fluticasone in the Airway

Asthma
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Zenapax in Combination With CellCept, Cyclosporine, and Corticosteroids in Patients Undergoing Cardiac Transplantation

Heart Transplantation

United States, Canada, Germany, Sweden
Takeda

Withdrawn

Efficacy of Naltrexone HCl/Bupropion HCl Extended Release Versus Placebo for Treatment of Weight Regain in Participants Post Bariatric Surgery

Weight Regain Post Bariatric Surgery

United States
Memorial Sloan Kettering Cancer Center

Completed

Effect of Affective Content on Drug Induced Amnesia of Episodic Memory

Memory Losses | Amnesia-Memory Loss

United States
Bayer

Completed

Acetylsalicylic Acid Combined With Pseudoephedrine in Common Cold

Common Cold

United Kingdom
H. Lundbeck A/S

Completed

Randomised Placebo-controlled Venlafaxine-referenced Study of Efficacy and Safety of 5 and 10 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in Adults

Major Depressive Disorder
Cady, Roger, M.D.
GlaxoSmithKline

Completed

CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet

Menstrual Migraine

United States
Cordis Corporation

Unknown

CYPRESS - CYPHER for Evaluating Sustained Safety

Coronary Artery Disease

United States
Pfizer

Completed

Study Of Safety And Efficacy Of PF-04991532 In Subjects With Type 2 Diabetes Mellitus

Diabetes, Type 2

Canada, United States, Korea, Republic of, Taiwan, Mexico, Hungary, Slovakia
XenoPort, Inc.

Completed

A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN)

Neuropathy, Diabetic

United States
XenoPort, Inc.

Completed

Study to Assess the Effect of Gabapentin Enacarbil on Simulated Driving in Healthy Subjects

Restless Legs Syndrome (RLS)

United States
Gilead Sciences

Completed

Study of Treatment of Antiretroviral-naive, HIV-1-Infected Patients Comparing Tenofovir Disoproxil Fumarate Administered in Combination With Lamivudine and Efavirenz vs. Stavudine, Lamivudine and Efavirenz.

HIV Infections
Fovea Pharmaceuticals SA

Completed

Evaluation of Efficacy of Coadministration of FOV1101-00 and Prednisolone Acetate in Patients With Mild Ongoing Ocular Allergic Inflammation

Allergic Conjunctivitis

United States
University of Wisconsin, Madison
National Institute on Drug Abuse (NIDA)

Completed

Smoking Cessation Medications: Efficacy, Mechanisms and Algorithms

Nicotine Dependence

United States
Abbott

Completed

A Study of Pain Relief in Low Back Pain

Chronic Low Back Pain

United States
Azienda Ospedaliera di Perugia

Unknown

Aprepitant for Prevention of Acute and Delayed Nausea and Vomiting in Patients Receiving a High-emetogenic Dose of Cyclophosphamide for Peripheral Blood Stem Cells Harvesting (PG-APRE1)

Nausea | Vomiting

Italy
Mahidol University
Siriraj Hospital

Unknown

Efficacy of Mefenamic Acid and Hyoscine for Pain Relief During Saline Infusion Sonohysterography in Infertile Women

Infertility

Thailand
Louisiana State University Health Sciences Center...
GlaxoSmithKline

Completed

Lamotrigine Augmentation in Resistant Depression

Unipolar Depression

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Colorectal Carcinoma | Refractory Colorectal Carcinoma

United States
University of Dublin, Trinity College
St. James's Hospital, Ireland

Not yet recruiting

Towards an Understanding of the Mechanism of Action of Methylphenidate in ADHD

Attention Deficit Hyperactivity Disorder
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Multicenter Phase II Double-Blind Exploratory Study to Evaluate Differences Among Various Zidovudine/Didanosine Regimens on Quantitative Measures of Viral Burden in Relatively Early HIV-1 Infection

HIV Infections

United States
Currax Pharmaceuticals

Recruiting

Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE) (INFORMUS)

Obesity

United States
Technical University of Munich

Recruiting

Safety, Tolerability and Symptomatic Efficacy of the ROCK-Inhibitor Fasudil in Patients With Parkinson's Disease

Idiopathic Parkinson´s Disease

Germany

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