Search clinical trials for: Placebo tofacitinib plus Methotrexate

Total 808 results

Pfizer

Completed

Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States, Mexico, Argentina, Chile, Croatia, Czech Republic, Hungary, Poland, Puerto Rico
Pfizer

Completed

An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate (ORAL STRATEGY)

Rhematoid Arthritis

Spain, United Kingdom, United States, Korea, Republic of, Poland, Israel, Australia, Taiwan, Thailand, South Africa, Bulgaria, Estonia, Latvia, Philippines, Canada, Romania, Russian Federation, Turkey, Mexico, Bosnia and Herzegovina and more
Pfizer

Completed

Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing Spondylitis

Ankylosing Spondylitis

Korea, Republic of, United States, Spain, Taiwan, Canada, Czech Republic, Poland, Hungary, Germany, Russian Federation
Pfizer

Completed

Efficacy Study Of Tofacitinib In Pediatric JIA Population

Juvenile Idiopathic Arthritis

United States, Spain, Turkey, Canada, Australia, Israel, United Kingdom, Argentina, Brazil, Poland, Mexico, Belgium, Russian Federation, Ukraine
Pfizer

Completed

Study Of The Mechanism Of Action Of CP-690,550 In The Skin Of Subjects With Moderate To Severe Chronic Plaque Psoriasis

Plaque Psoriasis

United States
Shanghai Zhongshan Hospital

Recruiting

Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients

Takayasu Arteritis | Methotrexate | Inhibition | Treatment

China
Gilead Sciences

Withdrawn

Study to Evaluate Safety, Tolerability, and Efficacy of GS-5718 in Participants With Active Rheumatoid Arthritis Who Have an Inadequate Response to Disease-modifying Antirheumatic Drug(s) (bDMARDs) Treatment

Rheumatoid Arthritis
Nanfang Hospital of Southern Medical University
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

Iguratimod Combined With Tofacitinib in the Treatment of Rheumatoid Arthritis

Rheumatoid Arthritis
Stanford University
National Institutes of Health (NIH)

Recruiting

Janus Kinase Inhibition to Prevent Ventilator-induced Diaphragm Dysfunction

Diaphragm Injury

United States
Ruijin Hospital

Recruiting

Novel Targeted Drugs Combined With R-ICE Regimen in Relapsed and Refractory Diffuse Large B-cell Lymphoma (R-ICE+X)

Diffuse Large B Cell Lymphoma

China
Hospital Israelita Albert Einstein
Pfizer

Completed

Tofacitinib in Hospitalized Patients With COVID-19 Pneumonia

Covid19

Brazil
Pfizer

Completed

A Study To Evaluate Both The Efficacy and Safety Profile of CP-690,550 In Patients With Moderately to Severely Active Ulcerative Colitis (OCTAVE)

Ulcerative Colitis

Korea, Republic of, United States, United Kingdom, Australia, Austria, Denmark, Canada, Israel, Germany, Belgium, Taiwan, Latvia, Spain, Poland, New Zealand, Hungary, Netherlands, France, Estonia, Serbia, South Africa, Slovakia, Cro... and more
Theravance Biopharma

Completed

TD-3504 SAD in Healthy Subjects and Subjects With Ulcerative Colitis (UC)

Active Mild Ulcerative Colitis, Active Moderate Ulcerative Colitis, Healthy Subjects

United States
Yale University

Terminated

Tofacitinib for Treatment of Moderate COVID-19 (I-TOMIC)

COVID-19 Pneumonia

United States
Pfizer

Completed

A Study Evaluating The Efficacy And Safety Of CP-690,550 In Patients With Moderate To Severe Ulcerative Colitis (OCTAVE)

Ulcerative Colitis

United States, Spain, Canada, Israel, Australia, Germany, Serbia, Japan, Denmark, France, Hungary, Poland, United Kingdom, Belgium, New Zealand, Netherlands, Austria, Colombia, Croatia, Czech Republic, Estonia, Italy, Latvia, Romania, Russian... and more
Pfizer

Completed

Co-Administration Of Methotrexate And CP-690,550

Rheumatoid Arthritis

United States
Pfizer

Completed

Tofacitinib Ointment For Atopic Dermatitis (Atopic Eczema)

Dermatitis, Atopic

Canada
Pfizer

Completed

A Study To Evaluate The Mechanism Of Action Of CP-690,550 In Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Unknown

Risk of Tuberculous and Other Infections in Patients of Spondyloarthritis Treated With Tofacitinib in Bangladesh

Spondyloarthritis

Bangladesh
Pfizer

Completed

Efficacy And Safety Of Tofacitinib In Psoriatic Arthritis: Comparator Study (OPAL BROADEN)

Psoriatic Arthritis

United States, Canada, Spain, Germany, Australia, Hungary, Belgium, Mexico, Poland, Russian Federation, Taiwan, United Kingdom, Slovakia, Czechia, Bulgaria, France
University of Oxford
Medical Research Council; Wellcome Trust

Terminated

Tofacitinib in Depression (TIDE) (TIDE)

Depression | Inflammation

United Kingdom
Globe Pharmaceuticals Limited

Completed

Safety and Efficacy of Tofacitinib vs Methotrexate in the Treatment of Psoriatic Arthritis (PsOLSET-BD)

Psoriatic Arthritis

Bangladesh
Pfizer

Completed

Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Korea, Republic of, United States, Poland, Bulgaria, Australia, Belgium, Hungary, Spain, United Kingdom, Czechia, Slovakia, Germany, Mexico, Philippines, Russian Federation, South Africa
Pfizer

Completed

Tofacitinib Ointment For Chronic Plaque Psoriasis

Psoriasis | Psoriasis Vulgaris

United States, Canada, Denmark, Poland
Shanghai University of Traditional Chinese Medicine
Fudan University; Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Chest... and other collaborators

Not yet recruiting

Clinical Study on the Prevention of Driver Gene Negative II-IIIa Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors

Lung Cancer

China
CAGE Bio Inc.

Not yet recruiting

Tolerability and Effectiveness of CGB-500 Topical Ointment, 1% Tofacitinib, for the Treatment of Atopic Dermatitis

Atopic Dermatitis
Charite University, Berlin, Germany

Recruiting

Tofacitinib for Reduction of Spinal Inflammation in Patients With Psoriatic ArthritiS PresenTing With Axial InvOlvement (PASTOR)

Spondylitis | Psoriatic Arthritis | Sacroilitis

Germany
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis

Rheumatoid Arthritis
Pfizer

Completed

A Safety, Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIA

Arthritis Juvenile Idiopathic

United States, Belgium, Spain, Canada, Mexico, Turkey, Israel, China, Slovakia, Hungary, India, Argentina, Brazil, Germany, South Africa, Poland, Ukraine, Italy, Costa Rica, Russian Federation, United Kingdom
Hansoh BioMedical R&D Company

Not yet recruiting

Efficacy and Safety of HS-10374 Compared to Placebo in Adults With Active Psoriatic Arthritis

Psoriatic Arthritis
Pfizer

Completed

Open-Label Extension Study Of Tofacitinib In Psoriatic Arthritis (OPAL BALANCE)

Arthritis, Psoriatic

Belgium, United States, Canada, Spain, Australia, Taiwan, Czechia, Hungary, Germany, Mexico, Poland, Russian Federation, Slovakia, United Kingdom, Brazil, Bulgaria
RemeGen Co., Ltd.

Terminated

A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Inadequate Response to TNF-α Antagonists Due to Treat Moderate and Severe Rheumatoid Arthritis

Moderate and Severe Rheumatoid Arthritis

China
Jiangsu vcare pharmaceutical technology co., LTD

Recruiting

Efficacy and Safety Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis.

Active Ankylosing Spondylitis

China
RemeGen Co., Ltd.

Completed

A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Inadequate Response to MTX Due to Treat Moderate and Severe Rheumatoid Arthritis.

Moderate and Severe RheumatoId Arthritis

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Greater Washington Community Foundation

Terminated

Muscadine Plus (MPX) In Men With Prostate Cancer

Adenocarcinoma of the Prostate

United States
National Institute of Dental and Craniofacial Research...

Recruiting

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome

Sjogren's Syndrome

United States
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Hetrombopag for the Treatment of Chemotherapy-Induced Thrombocytopenia in Adults With Solid Tumors.

Chemotherapy-Induced Thrombocytopenia
Heilongjiang University of Chinese Medicine

Recruiting

Chinese Herbal Medicine and Micronized Progesterone for Live Births in Threatened Miscarriage

Threatened Miscarriage

China
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de...

Completed

Synergic Effects of Ultrasound and Laser on the Pain Relief and Functionality

Osteoarthritis

Brazil
University of Memphis

Completed

Impact of JuicePlus+ on the Health Status of an Overweight Stressed Population

Inflammation

United States
National Institute of Arthritis and Musculoskeletal...

Completed

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
Pfizer

Completed

A Study To Evaluate The Effect Of CP-690,550 On Measures Of Kidney Function In Patients With Active Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Germany, Korea, Republic of, Spain, Czech Republic, Mexico, Poland, Russian Federation
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Uroial Plus in the Management of Infections and Urinary Symptoms Associated With Ureteral Stents (USSIAL)

Urinary Tract Infections | Ureteral Stent-Related Symptom
Government Dental College and Research Institute...

Completed

Clinical Efficacy of 0.75% Boric Acid Gel in Chronic Periodontitis

Chronic Periodontitis

India
Massachusetts General Hospital
Vedanta Biosciences, Inc.

Recruiting

VE416 for Treatment of Food Allergy

Peanut Allergy

United States
Birmingham Community Healthcare NHS
NSA, LLC

Completed

Effect of Dietary Intake of Dried Whole Food Concentrates (Juice Plus) on Clinical Outcomes Following Periodontal Therapy: A Pilot Study (BHAM-NSA-05-01)

Periodontitis

United Kingdom
Hospital Clínico Universitario de Valladolid

Unknown

Salt Intake, Microbiota, Immune Response and Endothelial Function in Hypertension

Hypertension

Spain
China National Center for Cardiovascular Diseases
Fuwai Hospital, Chinese Academy of Medial Sciences, Shenzhen, Shenzhen

Recruiting

Effects of Dengzhanxixin Capsule on Platelet Function in Individuals at High Risk for Cardiovascular Disease (FUTURE)

Hypertension | Diabetes | Hypercholesterolemia

China
Pfizer

Completed

The Safety And Efficacy Of Maintenance Therapy With CP-690,550

Crohn's Disease

United States, Spain, Israel, Netherlands, Australia, Canada, Japan, Germany, Korea, Republic of, Hungary, Austria, Bulgaria, Czech Republic, Greece, South Africa, Ukraine, France
Pfizer

Completed

Effectiveness and Safety of 3 Dosing Regimens of CP-690,550 to Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis

United States, Canada

Search clinical trials for: Placebo tofacitinib plus Methotrexate

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