Search clinical trials for: Profound neuromuscular blockade (Rocuronium, Rocuronium bromide, sugammadex, Bridion)

Total 114 results

University Hospital, Antwerp

Completed

Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex (SUDIA)

Muscle Weakness | Muscle Fatigue | Diaphragmatic Dysfunction

Belgium
University of Missouri-Columbia
Merck Sharp & Dohme LLC

Enrolling by invitation

Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery

Spine Surgery | Urinary Retention Postoperative | Reversal of Neuromuscular Blockade

United States
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex Administered at 1-2 Post Tetanic Counts (PTCs) or Better With Neostigmine Administered as Per Standard of Care to Reverse Rocuronium-Induced Neuromuscular Blockade in Adults Undergoing Elective Open Abdominal Procedure (19.4.334) (P05774)

Anesthesia
Centro Hospitalar do Porto
Merck Sharp & Dohme LLC

Completed

Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade?

Neuromuscular Block

Portugal
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Innate Immune Homeostasis. (RECOVER-PLUS)

Pneumoperitoneum | Surgery | Neuromuscular Blockade | Immune Suppression

Netherlands
NYU Langone Health

Completed

Determination of TOF Test Threshold for Obtaining Reliable Pedicle Screw Stimulation Test During Lumbar Spine Surgery

Neuromuscular Blockade

United States
Craig Curry
MaineHealth; Spectrum Medical Group Anesthesiology

Completed

Does Deep Neuromuscular Blockade Improve Operating Conditions During Total Hip Replacements?

Arthropathy of Hip

United States
Merck Sharp & Dohme LLC

Completed

Sugammadex After Continuous Infusion of Rocuronium During Sevoflurane and Propofol Anesthesia (P05949; MK-8616-028)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

A Study to Compare Different Intubating Doses of Zemuron in Pediatric and Adolescent Subjects Under General Anesthesia

Anesthesia
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Investigation of Sugammadex in Outpatient Urological Procedures

Bladder Cancer | Malignant Neoplasms of Urinary Tract

United States
Clinical Hospital Centre Zagreb

Enrolling by invitation

General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery

Muscle Weakness | General Anaesthesia | Rocuronium

Croatia
Dr. Horst Schmidt Klinik GmbH

Completed

Muscle Relaxation for Short Procedures

Patient Satisfaction | Sore Throat | Intubating Conditions | Postoperative Myalgia | Fasciculations

Germany
Istanbul University
Ayse Cigdem Tutuncu; GAMZE PİRİNÇ ŞAŞIOĞLU; GÜNER KAYA

Completed

Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in Children

Anesthesia, General | Anesthetics, Inhalation | Neuromuscular Blockade

Turkey
University Hospital of Split

Recruiting

Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants

Anesthesia | Neuromuscular Blockade | Intraoperative Bleeding | Anesthesia Complication | Post Operative Hemorrhage | Intraoperative Blood Loss

Croatia
Konkuk University Medical Center

Completed

Deep Neuromuscular Block on Cytokines Release and Postoperative Delirium

Hip Fractures

Korea, Republic of
Korea University Anam Hospital

Unknown

Evaluation of EEG With Respect to the Change of Depth of Anesthesia During General Anesthesia

Anesthesia
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Sugammadex (Org 25969, MK-8616) in Participants With or Having a Past History of Pulmonary Disease (19.4.308) (P05932) (MK-8616-017)

Anesthesia, General
Peking University First Hospital
Xiangya Hospital of Central South University; Peking Union Medical College... and other collaborators

Unknown

A Study of Residual Curarization Incidence in China

Perioperative/Postoperative Complications | PORC (Postoperative Residual Curarization)

China
Brno University Hospital
KDCHOT FN Brno

Completed

Depth of Neuromuscular Blockade and the Perioperative Conditions in Laparoscopic Surgery in Pediatric Population (PedLapBlock)

Neuromuscular Blockade

Czechia
Yonsei University

Completed

The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy

Robot-Assisted Laparoscopic Radical Prostatectomy

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex With Neostigmine During Laparoscopic Cholecystectomy or Appendectomy (P05699)

Anesthesia, General
Herlev Hospital

Completed

Validation of Subjective Rating Scales Used to Assess Surgical Conditions in Abdominal Surgery

Pneumoperitoneum | Laparoscopy | Neuromuscular Blockade | Surgical Conditions | Rating Scales

Denmark
Korea University Anam Hospital

Unknown

The Effect of no Muscle Relaxant Versus Reduced-dose Rocuronium on Anesthesia in Adenotonsillectomy

Muscle Relaxants
Merck Sharp & Dohme LLC

Completed

Study of Efficacy, Pharmacokinetics and Safety of Continuous Intravenous Infusion of Org 9426 (Study P05977)

Anesthesia
Leiden University Medical Center

Completed

Effect of Deep BLock on Intraoperative Surgical Conditions (BLISS)

Renal Disease | Prostate Hypertrophy

Netherlands
Merck Sharp & Dohme LLC

Completed

Study of Efficacy, Pharmacokinetics, and Safety of Bolus Maintenance Doses of Org 9426 (Study P05976)(COMPLETED)

Muscle Relaxation
R-Pharm
Synergy Research Inc.

Completed

Comparative Clinical Study of Efficacy and Safety of Remimazolam and Propofol in Patients Undergoing Elective Surgery Under General Anaesthesia

General Anaesthesia

Russian Federation
Merck Sharp & Dohme LLC

Completed

Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023)

Anesthesia, General
University of Texas Southwestern Medical Center

Completed

Neuromuscular Blockade in Patients With Severe Renal Impairment

Renal Impairment | Neuromuscular Blockade

United States
Sir Ganga Ram Hospital

Unknown

Evaluation of Atracurium-vecuronium Combination in Laparosocpic Surgery

Patients Undergoing Laparoscopic Surgery

India
TC Erciyes University

Unknown

Effects of Low Dose Neuromuscular Blocker Usage on Laryngeal Mask Application

Anesthesia

Turkey
Merck Sharp & Dohme LLC

Completed

Comparison of Recovery From Rocuronium 1.2 mg/kg Followed by Sugammadex (Org 25969) 16 mg/kg at 3 Minutes With Recovery From Succinylcholine 1.0 mg/kg (19.4.303)(P05946)(MK-8616-026)

Anesthesia, General
University of Sao Paulo General Hospital
Magnamed Tecnologia Medica S/A

Completed

Muscle Pressure Estimation With Artificial Intelligence During Mechanical Ventilation

Respiratory Failure

Brazil
Institut Jantung Negara

Completed

Rocuronium vs Cis-atracurium: Do Rocuronium Still 'ROCKS' In Coronary Artery Bypass Grafting

Coronary Artery Disease | Neuromuscular Blockade | Coronary Artery Bypass Grafting | Postoperative Pulmonary Complication | Postoperative Pulmonary Atelectasis | Hypothermic Cardiopulmonary Bypass

Malaysia
University of Texas Southwestern Medical Center
Merck Sharp & Dohme LLC

Recruiting

Muscle Relaxation for Pediatric Adenotonsillectomy

Tonsillectomy

United States
University of Washington

Completed

Best Management of Muscle Relaxation- Objective Monitoring

Residual Paralysis, Post Anesthesia

United States
McGill University Health Centre/Research Institute...

Unknown

The Use of Sugammadex in the Critically Ill

Critical Illness

Canada
Ain Shams University

Active, not recruiting

Role of Sugammadex and Neostigmine for Recovery From Rocuronium

Anesthesia

Egypt
Ain Shams University

Completed

Effect of Atracurium and Rocuronium on the State and Response Entropy During Isoflurane Anesthesia

Entropy Device and How Will Muscle Relaxants Affect it

Egypt
Cairo University
National Liver Institute, Egypt

Completed

Sugammadex Versus Neostigmine in Patients With Liver Cirrhosis Undergoing Liver Resection

Cirrhosis and Chronic Liver Disease

Egypt
Loyola University

Withdrawn

GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture

Anesthesia, General | Hip Fractures | Neuromuscular Blockade | Anesthesia, Spinal

United States
Merck Sharp & Dohme LLC

Completed

Observational Study to Evaluate the Current Neuromuscular Monitoring Practice Used After Different Types of Surgery, for Which Neuromuscular Blocking Agents Were Used, With or Without Blocking Reversal (P06556)

Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
Brno University Hospital
University Hospital Olomouc; St. Anne's University Hospital Brno, Czech Republic and other collaborators

Completed

Modern Myorelaxation Procedure and Reversal of Neuromuscular Blockade With General Anesthesia for Caesarean Section (RocSugIO)

Caesarean Section | Pregnancy

Czech Republic
Zheng Guo

Completed

Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery (RUILS)

Spinal Stenosis Lumbar

China
Tang-Du Hospital

Unknown

Effects of Dexmedetomidine on Postoperative Cognitive Dysfunction During One-lung Ventilation in Elder Patients

Postoperative Confusion
Assiut University

Not yet recruiting

Effect of Magnesium Sulphate Pretreatment in Pediatric Laparoscopy (MgSO4/MR)

Muscle Relaxation

Egypt
Second Hospital of Shanxi Medical University

Recruiting

Cardiovascular Protection Conservative Effects of Esketamine Versus µ-opioid Receptor Agonists in General Anesthesia

Opioid Analgesic Adverse Reaction

China
Jakob Louis Thomsen
Merck Sharp & Dohme LLC

Completed

Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals

Neuromuscular Blockade

Denmark
Samsung Medical Center

Completed

Comparison of the Effects of Vecuronium and Cisatracurium on Electrophysiologic Monitoring During Neurosurgery

Brain Tumor | General Anesthesia | Cerebral Aneurysm | Neurosurgery | Spine Tumor | Motor Evoked Potential Monitoring

Korea, Republic of
West Virginia University

Completed

Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting Surgery

Coronary Artery Disease | Surgery

United States

Search clinical trials for: Profound neuromuscular blockade (Rocuronium, Rocuronium bromide, sugammadex, Bridion)

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