Search clinical trials for: Protein Synthesis Inhibitors

Total 68372 results

Memorial Sloan Kettering Cancer Center
AstraZeneca; Guardant Health, Inc.

Recruiting

Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers

Metastatic Non-small Cell Lung Cancer

United States
Andres J. M. Ferreri

Completed

Salvage Therapy With High Dose Oral Clarithromycin in Relapsed or Refractory Extranodal Marginal Zone Lymphoma (HD-K)

Lymphoma

Italy
Janssen Research & Development, LLC

Completed

A Study to Assess the Drug-Drug Interaction Between Bedaquiline and Clarithromycin in Healthy Adult Participants

Healthy

Belgium
Abbott

Completed

Outcome Study to Evaluate Klaricid XL® (Clarithromycin Modified Release) in Patients With Acute Exacerbation of Chronic Bronchitis

Bronchitis

Pakistan
Mylan Pharmaceuticals Inc
Genpharm ULC

Completed

Comparative Bioavailability Study of Clarithromycin 500 mg Tablets in Fasting State

Healthy

Canada
Women and Infants Hospital of Rhode Island

Not yet recruiting

Intravesical Gentamicin to Prevent Recurrent UTI

Recurrent Uti
October 6 University
Beni-Suef University

Recruiting

Continuous Infusion of Linezolid Versus Intermittent Dosing in the Treatment of Nosocomial Pneumonia

Pneumonia

Egypt
University of California, San Francisco
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Pilot RCT Local Gentamicin for Open Tibial Fractures in Tanzania (pGO-Tibia)

Open Tibia Fracture

Tanzania
University of Oxford
Merck Sharp & Dohme LLC

Active, not recruiting

REVEAL: Randomized EValuation of the Effects of Anacetrapib Through Lipid-modification (REVEAL)

Atherosclerotic Cardiovascular Disease

United Kingdom
Stryker Orthopaedics

Completed

Retrospective Simplex High Viscosity (HV) Bone Cement Study

Arthritis Knee | Aseptic Loosening
Bayer

Terminated

Sivextro in Acute Bacterial Skin and Skin Structure Infection (ABSSSI) in Hospitalized Patients. A Global Observational Study (DART)

Skin Disease, Infectious

Russian Federation, Mexico, Singapore
Prince of Songkla University

Unknown

Linezolid in Healthy Volunteers

Healthy

Thailand
Mahidol University

Unknown

The Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis and Recurrent Sinusitis

Rhinosinusitis

Thailand
Seoul National University Hospital
Pfizer; Seoul National University Bundang Hospital; SMG-SNU Boramae Medical Center and other collaborators

Unknown

Linezolid Instead of Ethambutol in Treatment of Drug-susceptible Tuberculosis

Pulmonary Tuberculosis Without Resistance to Rifampicin

Korea, Republic of
Mette Møller Handrup

Unknown

Scars After Central Venous Catheters

Hypertrophic Scars | Keloids

Denmark
Sequella, Inc.

Completed

Safety, Tolerability And Pharmacokinetics Study Of Single Doses Of PNU-100480 In Healthy Adults

Tuberculosis

United States
Canisius-Wilhelmina Hospital

Completed

Assess the Effect of Erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube

Pancreatitis
Albert Schweitzer Hospital

Completed

Treatment of Malaria in Gabon With Fosmidomycin-Clindamycin

Malaria

Gabon
Memorial Sloan Kettering Cancer Center
Boehringer Ingelheim; National Comprehensive Cancer Network

Withdrawn

Afatinib In Combination With Cisplatin Or Carboplatin + Pemetrexed In Patients With EGFR-Mutant Lung Cancers Undergoing Definitive Chemoradiation

Non-small Cell Lung Cancer
National Institute of Allergy and Infectious Diseases...

Completed

The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Tanzania
Memorial Sloan Kettering Cancer Center

Completed

Biaxin Based Antibiotic Therapy in Previously Untreated, Advanced Stage Indolent Lymphoma

Lymphoma

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Royal Liverpool University Hospital
Abbott

Completed

Clarithromycin in Active Crohn's Disease

Crohn's Disease

United Kingdom
Hunan Province Tumor Hospital

Recruiting

ALK Tyrosine Kinase Inhibitors in ALK-rearranged Advanced Squamous Cell Carcinoma (ATPase)

Non-small Cell Lung Cancer

China
Rigshospitalet, Denmark

Completed

Study of the Ability of Clarithromycin to Induce Oxidative Stress (CLAROX)

Oxidative Stress

Denmark
Cairo University

Recruiting

Ozonated Olive Oil in Treatment of Pemphigus Vulgaris and Bullous Pemphigoid

Bullous Pemphigoid | Pemphigus Vulgaris

Egypt
Merck Sharp & Dohme LLC

Completed

Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016)

Hospital-Acquired Bacterial Pneumonia | Ventilator-Associated Bacterial Pneumonia

Mexico, Brazil, China, France, Philippines, Romania, Russian Federation, Ukraine
UCB Biopharma S.P.R.L.

Completed

Study to Evaluate the Effect of Coadministered Erythromycin on the Pharmacokinetics and Safety of Padsevonil

Pharmacokinetics

United Kingdom
Beijing Children's Hospital

Unknown

Long-term Prognosis of Children With Bronchiectasis Treated With Low-dose Erythromycin Intervention

Bronchiectasis
Arrevus Inc.

Completed

Oral Sodium Fusidate (CEM-102) Versus Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Acute Bacterial Skin and Skin Structure Infections

United States, Puerto Rico
Melinta Therapeutics, Inc.

Completed

Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections

Streptococcal Infections | Abscess | Staphylococcal Skin Infections | Infectious Skin Diseases | Bacterial Skin Diseases

United States
Obafemi Awolowo University Teaching Hospital

Completed

Treatment of Antenatal Chlamydia Infection

Chlamydia Trachomatis Infection in Pregnancy

Nigeria
International Extranodal Lymphoma Study Group (IELSG)

Completed

A Clinico-Pathological Study to Investigate the Possible Infective Causes of Non-Hodgkin Lymphoma of the Ocular Adnexae (IELSG27)

Non-Hodgkin Lymphoma

Spain, Italy, Switzerland, Chile
GlaxoSmithKline

Completed

United States Pharmacovigilence Retapamulin-Prescribing

Skin Infections, Bacterial
Ganga Hospital

Unknown

Efficacy of Local Powder Prophylactics

Infection

India
Yonsei University

Not yet recruiting

Lazertinib and Chemotherapy Combination in EGFR-mutant NSCLC Patients Without ctDNA Clearance After lead-in Lazertinib Monotherapy (CHAMELEON)

Non Small Cell Lung Cancer

Korea, Republic of
Jin Hyoung Kang
Korea University Anam Hospital

Not yet recruiting

Lazertinib/Pemetrexed/Carboplatin After Osimertinib Failure in NSCLC With Brain Metastases

Non-small Cell Lung Cancer

Korea, Republic of
Goethe University

Recruiting

Additional Chemotherapy for EGFRm Patients With the Continued Presence of Plasma ctDNA EGFRm at Week 3 After Start of Osimertinib 1st-line Treatment (PACE-LUNG)

NSCLC Stage IV | NSCLC Stage IIIB

Germany
Memorial Sloan Kettering Cancer Center
Genentech, Inc.

Completed

Erlotinib and Chemotherapy for Patients With Stage IB-IIIA NSCLC With EGFR Mutations (ECON)

Lung Cancer | Non Small Cell Lung Cancer

United States
Novartis Pharmaceuticals

Completed

Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive Glioblastoma

Astrocytoma | Glioblastoma Multiforme

Germany
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Clinical Study Protocol of Venetoclax Combined With Azacitidine and Harringtonine in the Treatment of sAML

Secondary Acute Myeloid Leukemia

China
University of California, San Francisco
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

Adjunctive Linezolid for the Treatment of Tuberculous Meningitis (ALTER)

Tuberculosis, Meningeal

Uganda
LegoChem Biosciences, Inc

Completed

A Mass Balance Study of LCB01-0371 After a Single Oral LCB01-0371 Dose With a [14C]LCB01-0371-microtrace

Healthy

Korea, Republic of
PHARMENTERPRISES LLC

Completed

XC8 Safety, Tolerability and Pharmacokinetics in Healthy Volunteers

Asthma

Russian Federation
Zentopharm GmbH
Centro de Investigação em Saúde de Manhiça; Albert Schweitzer Hospital

Unknown

Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria

Malaria

Gabon
University Medical Center Groningen

Completed

BURULICO Drug Trial Study Protocol: RCT SR8/SR4+CR4, GHANA (BURULICO)

Buruli Ulcer | Mycobacterium Ulcerans

Ghana
Universiteit Antwerpen
Abbott

Completed

Selection of Antibiotic Resistance by Azithromycin and Clarithromycin in the Oral Flora

Healthy Volunteers

Belgium
Beijing Cancer Prevention & Treatment Society
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Recruiting

Osimertinib Plus Chemotherapy vs Osimertinib in EGFRm NSCLC With Persistence Week-3 ctDNA EGFRm After 1L Osimertinib (FLAME)

Non Small Cell Lung Cancer

China
Novartis Pharmaceuticals

Completed

LDK378 Versus Chemotherapy in Previously Untreated Patients With ALK Rearranged Non-small Cell Lung Cancer

Non-Small Cell Lung Cancer

Italy, Spain, Taiwan, Germany, Netherlands, Singapore, Austria, Japan, Australia, France, Russian Federation, Sweden, Thailand, Korea, Republic of, Lebanon, Norway, United Kingdom, China, India, Brazil, Turkey, Poland, Denmark, Greece, ... and more
Samsung Medical Center

Completed

Pemetrexed Plus Tarceva as Salvage Treatment in EGFR Overexpressed Metastatic Colorectal Cancer Patients Who Were Failed After Standard Chemotherapy

Colo-rectal Cancer

Korea, Republic of

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