Search clinical trials for: Proteolytic enzymes

Total 47656 results

Eli Lilly and Company

Completed

Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes

Diabetic Neuropathies | Diabetes Mellitus, Non-Insulin-Dependent | Diabetes Mellitus, Insulin-Dependent

United States, Spain, Hungary, Australia, Belgium, Denmark, Estonia, Germany, Israel
Adherex Technologies, Inc.

Completed

A Study of ADH300004 in Surgically Resected Primary or Metastatic Colorectal Cancer and Liver Biopsy, or Planned Hepatic Resection

Neoplasms

United States
Universitätsklinikum Hamburg-Eppendorf

Completed

Metyrapone as Additive Treatment in Major Depression

Major Depressive Disorder

Germany
Federal University of São Paulo

Recruiting

Methylene Blue for the Prevention of Hypotension During Hemodialysis (BLUE)

Shock | Acute Kidney Injury

Brazil
Servier

Active, not recruiting

A Phase 2 Study of Ivosidenib in Previously Treated Japanese Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Cholangiocarcinoma Non-resectable | Cholangiocarcinoma Metastatic

Japan
Massachusetts General Hospital
Agios Pharmaceuticals, Inc.

Completed

IDH1 Inhibition Using Ivosidenib as Maintenance Therapy for IDH1-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation

IDH1 Mutation Myeloid Neoplasms

United States
Mark Gladwin

Completed

A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases

Sickle Cell Disease

United States
AstraZeneca

Completed

Safety, Tolerance, PK, and Anti-tumour Activity of AZD1775 Monotherapy in Patients With Advanced Solid Tumours

Ovarian Cancer, TNBC, SCLC, Other Solid Tumours

United States, Canada
Medical University of Vienna

Completed

Pharmacodynamic Effects of Riociguat in Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (DYNAMIC)

Hypertension, Pulmonary | Heart Failure With Normal Ejection Fraction

Austria
University of Cincinnati

Unknown

Riociguat for Sarcoidosis Associated Pulmonary Hypertension (RioSAPH)

Sarcoidosis

United States
Gemin X

Completed

Study of Obatoclax in Previously Untreated Acute Myeloid Leukemia (AML)

AML

United States, Canada
Min-Sheng General Hospital

Unknown

Probiotics Improve Gastrointestinal Symptoms After Roux-en-Y Gastric Bypass: A Prospective Randomized Trial

Morbid Obesity

Taiwan
Athenex, Inc.

Completed

Evaluation of KX2-391 in Patients With Advanced Malignancies

Lymphoma | Solid Tumors

United States
Fore Biotherapeutics

Recruiting

A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Volunteers.

Healthy Volunteer

United States
Syndax Pharmaceuticals

Recruiting

A Study of SNDX-5613 in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation (AUGMENT-101)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Acute Leukemia of Ambiguous Lineage | Mixed Phenotype Acute Leukemia | Mixed Lineage Acute Leukemia

United States, Israel, Spain, Australia, Netherlands, Germany, Canada, France, Italy, Lithuania
Andres J. M. Ferreri

Completed

Salvage Therapy With High Dose Oral Clarithromycin in Relapsed or Refractory Extranodal Marginal Zone Lymphoma (HD-K)

Lymphoma

Italy
British University In Egypt

Completed

Modified Surface of PLGA Nanoparticles in Smart Hydrogel

Antibiotic Resistant Infection

Egypt
University of Maryland, Baltimore
Food and Drug Administration (FDA)

Completed

Impact of Formulation on Ciprofloxacin Oral Absorption

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Completed

Clinical Validation of a Molecular Test for Ciprofloxacin-Susceptibility in Neisseria Gonorrhoeae

Gonococcal Infection

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Drug-Drug Interaction Between Bedaquiline and Clarithromycin in Healthy Adult Participants

Healthy

Belgium
Boehringer Ingelheim

Completed

Trial to Compare the Effects of Either Telmisartan (40-80 mg PO Once Daily) or Ramipril (5-10 mg PO Once Daily) on Renal Endothelial Dysfunction in Hypertensive Patients With Type 2 Diabetes

Hypertension | Diabetes Mellitus, Type 2

Germany, France, Spain
Boehringer Ingelheim

Completed

Prospective Randomised Investigation of the Safety and Efficacy of Micardis® vs Ramipril Using ABPM (PRISMA)

Hypertension

United Kingdom, Switzerland, Austria, France, Germany, Netherlands, South Africa, Spain
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Crohn...

Completed

Ciprofloxacin for the Prevention of Postoperative Endoscopic Recurrence in Crohn's Disease

Crohn's Disease

United States
Abbott

Completed

Outcome Study to Evaluate Klaricid XL® (Clarithromycin Modified Release) in Patients With Acute Exacerbation of Chronic Bronchitis

Bronchitis

Pakistan
Rigshospitalet, Denmark

Unknown

Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosis

Aortic Stenosis

Denmark
Mylan Pharmaceuticals Inc
Genpharm ULC

Completed

Comparative Bioavailability Study of Clarithromycin 500 mg Tablets in Fasting State

Healthy

Canada
Academisch Ziekenhuis Maastricht
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Timely Recovery After Subclinical Heart Failure (TREASURE)

Heart Failure | Diastolic Dysfunction

Netherlands
H. Lee Moffitt Cancer Center and Research Institute

Active, not recruiting

Adaptive Abiraterone Therapy for Metastatic Castration Resistant Prostate Cancer

Prostate Cancer

United States
Teva Pharmaceuticals USA

Completed

Benazepril HCl 40 mg Tablets, Fed

Healthy

United States
Epicentre
Medecins Sans Frontieres, Netherlands

Withdrawn

Ciprofloxacin for the Prevention of Meningococcal Meningitis 2018

Meningitis, Meningococcal

Niger
University Ghent

Completed

Dose Titration of Lisinopril in Children Aged 1 to 18 Years With Primary or Secondary Hypertension (Lisi-ped)

Primary Hypertension | Secondary Hypertension

Belgium
Azienda Socio Sanitaria Territoriale degli Spedali...
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; Niguarda Hospital; San... and other collaborators

Unknown

Activity of Abiraterone Acetate in the Management of Cushing's Syndrome in Patients With Adrenocortical Carcinoma (ABACUS)

Cushing Syndrome | Adrenocortical Carcinoma

Italy
Bayer

Completed

Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters. (PATENT PLUS)

Pulmonary Hypertension

Spain, New Zealand, Germany, Austria, United States, Poland, Italy, United Kingdom, Czech Republic
University of Chicago

Terminated

Randomized Trial of Ciprofloxacin Versus Observation for Men With Elevated Prostate Specific Antigen (PSA)

Elevated Prostate Specific Antigen

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Parameters Associated With the Emergence of Resistance to Ciprofloxacin in Human Commensal Flora

Healthy Volunteers

France
Poitiers University Hospital

Terminated

Short or Long Schemes of Antibiotic Prophylaxis for Prostate Biopsy

Men Who Must Undergo a Prostate Biopsy Related to Prostate Cancer Suspicion.

France
Bayside Health

Unknown

Vasoactive Peptides in Portal Pressure

Portal Hypertension

Australia
Peking Union Medical College Hospital

Unknown

Efficacy of Efavirenz 400mg vs. 600mg Combined With Lamivudine and Tenofovir in Treatment Naive HIV Infection

HIV/AIDS | Mental Impairment

China
Adeniyi Olagunju
Obafemi Awolowo University Teaching Hospital; University of Liverpool

Completed

A Study to Evaluate the Effects of Genetic Factors on the Pharmacokinetics of Antiretroviral Drugs During Pregnancy and Lactation

Pregnancy | HIV | Breastfeeding

Nigeria
University of Minnesota

Completed

Sustiva Levels With Use of a Gel Capsule

HIV Infections | HIV

United States
Boehringer Ingelheim

Terminated

Pharmacokinetic Interaction Between Nevirapine and Saquinavir-sgc in HIV-1 Infected Patients

HIV Infections
Bristol-Myers Squibb

No longer available

An Expanded Access Study of Oral Liquid Efavirenz in the Treatment of Children With HIV Infection

HIV Infection

United States, Puerto Rico
University of Alabama at Birmingham

Completed

The Fabrazyme® and Arbs and ACE Inhibitor Treatment (FAACET) Study (FAACET)

Proteinuria | Fabry Disease

United States, Slovenia
Janssen-Cilag International NV

Completed

A Clinical Trial Comparing the Tolerability of Etravirine to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Treatment-naive HIV-1 Infected Patients (SENSE)

Acquired Immunodeficiency Syndrome | HIV Infection | HIV

France, United Kingdom, Germany, Spain, Switzerland, Israel, Russian Federation, Austria, Hungary, Romania, Denmark
St Stephens Aids Trust

Completed

Pilot Study Switching Individuals Receiving EFV With Continuing Central Nervous System Toxicity to TMC125

HIV

United Kingdom
Cyclerion Therapeutics

Completed

A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers

Healthy

United States
Germans Trias i Pujol Hospital

Completed

Modification of Doses of Efavirenz According to Its Blood Concentration in HIV Patients

HIV

Spain
Bristol-Myers Squibb

No longer available

An Expanded Access Study of Oral Liquid Efavirenz in the Treatment of Children With HIV Infection: Canada

HIV Infection

Canada
Bamrasnaradura Infectious Diseases Institute
Thai Red Cross AIDS Research Centre; Clinical Research Collaborative Network

Completed

Effectiveness of Efavirenz-based Regimen in HIV-1-infected Patients With Nevirapine Hypersensitivity

Treatment Failure, HIV or AIDS | CD4 Cell Counts

Thailand
Pharmtechnology LLC

Recruiting

Bioequivalence Study of Perindopril Tablets in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation

Search clinical trials for: Proteolytic enzymes

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