Search clinical trials for: Pyruvate (13C)

Total 1981 results

Bristol-Myers Squibb

Completed

A Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]BMS-986419 in Healthy Male Participants

Healthy Volunteers

United States
National Cardiovascular Center Harapan Kita Hospital...

Completed

Transepicardial With Transseptal Autologous CD 133+ Bone Marrow Cell Implantation in Patient Following CABG Surgery

Coronary Artery Disease

Indonesia
Christine Elizabeth Edmonds

Withdrawn

Imaging With [11C]Martinostat in Breast Cancer

Breast Cancer

United States
Seoul National University Hospital

Unknown

To Investigate the Absorption, Metabolism, Excretion, Absolute Bioavailability, and Immunogenicity of GX-I7 in Healthy Volunteers

Leukopenia

Korea, Republic of
Biocad

Unknown

A Study of BCD-135 in Patients With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | NSCLC | Bladder Cancer

Russian Federation
Senju USA, Inc.

Completed

Safety and Efficacy Study of SUN 131 TDS as Compared to Placebo TDS in Adult Patients With a Chalazion

Chalazion

United States
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY

Healthy Volunteers

United States
Anthera Pharmaceuticals

Terminated

Phase III ALTU-135 CP Safety Trial (DIGEST CP)

Exocrine Pancreatic Insufficiency

United States
Seoul National University Hospital

Completed

Absolute Bioavailability of YH4808 With Accelerator Mass Spectrometry(AMS)-Based Microdose Study

Gastroesophageal Reflux Disease

Korea, Republic of
Galapagos NV

Completed

Investigation of the Pharmacokinetics and Metabolism of GLPG0634 in Healthy Male Subjects

Healthy

United Kingdom
Stealth BioTherapeutics Inc.

Completed

A Trial to Evaluate Safety, Tolerability and Efficacy of Elamipretide in Subjects With Barth Syndrome (TAZPOWER)

Barth Syndrome

United States
Alexion Pharmaceuticals

Completed

Study of Radiolabeled ALXN2050 in Healthy Adult Males

Healthy

United States
Senju USA, Inc.

Completed

Safety and Efficacy Study of SUN-131 Transdermal System (TDS) as Compared to Placebo TDS in Patients With a Chalazion (SUNRISE)

Chalazion

United States
Massachusetts General Hospital
Genentech, Inc.

Unknown

Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation

Multiple Sclerosis
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [18F]AZD4694 and [11C]AZD2184, Candidate PET Ligands for Aβ Amyloid (PET)

Alzheimer's Disease

Sweden
University of Michigan Rogel Cancer Center
GlaxoSmithKline

Active, not recruiting

Clinical Trial of Consolidation Treatment With Iodine I 131 Tositumomab for Multiple Myeloma

Multiple Myeloma

United States
University of Edinburgh
NHS Lothian

Terminated

Visualising c-MET and Activated Neutrophils in Lung Cancer (DUAL)

Lung Cancer

United Kingdom
United Therapeutics

Completed

Effect of Food on the Pharmacokinetics of Oral Treprostinil

Pulmonary Arterial Hypertension | Hypertension, Pulmonary

United States
Pfizer

Completed

A Study to Learn About Effect of Sisunatovir in Healthy Adult Male Participants

Respiratory Syncytial Virus Infections

United States
University of Cologne
Boehringer Ingelheim; ZKS Köln

Completed

SARS-CoV-2-Neutralizing Monoclonal COVID-19 Antibody DZIF-10c by Infusion

SARS-CoV-2 Infection

Germany
The Cleveland Clinic
Fresenius Kabi

Completed

Use of 6% Hydroxyethylstarch (130/0.4) in Cardiac Surgical Patients (SHARP)

Postoperative Kidney Injury

United States
University of Cologne
Boehringer Ingelheim; ZKS Köln

Completed

SARS-CoV-2-Neutralizing Monoclonal COVID-19 Antibody DZIF-10c by Inhalation

SARS-CoV-2 Infection

Germany
Seoul National University Hospital

Completed

The Effect of the Hydroxyethyl Starch on Kidney Injury in Pediatric Cardiac Surgery

Acute Kidney Injury

Korea, Republic of
AstraZeneca

Completed

Evaluation of Histamine H3 Receptor Radioligand [11C]AZ12807110 and Histamine H3 Receptor Occupancy of AZD5213 After Oral Administration

Brain Distribution of [11C]AZ12807110 and AZD5213

Sweden
Teva Branded Pharmaceutical Products R&D, Inc.
Covance

Terminated

A Study to Investigate the Absorption, Metabolism and Excretion of Talampanel

Healthy

United States
Hutchmed

Active, not recruiting

Human Mass Balance of [14C]HMPL-523 in Healthy Adult Male Chinese Subjects

Imumune Thrombocytopenia(ITP) Human Mass Balance

China
University of Washington
National Cancer Institute (NCI); GlaxoSmithKline; National Comprehensive Cancer...

Completed

Iodine I 131 and Pazopanib Hydrochloride in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer Previously Treated With Iodine I 131 That Cannot Be Removed By Surgery

Recurrent Thyroid Cancer | Stage IVA Follicular Thyroid Cancer | Stage IVA Papillary Thyroid Cancer | Stage IVB Follicular Thyroid Cancer | Stage IVB Papillary Thyroid Cancer | Stage IVC Follicular Thyroid Cancer | Stage IVC Papillary Thyroid Cancer

United States
GlaxoSmithKline

Completed

Study of Untreated or Transformed Follicular Non-Hodgkin's Lymphoma With Fission-Derived Iodine I 131 Tositumomab

Non-Hodgkin's Lymphoma

United States
Johns Hopkins University
United States Department of Defense

Not yet recruiting

Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS

ALS
Rush University Medical Center
GlaxoSmithKline; Millennium Pharmaceuticals, Inc.

Terminated

A Phase II Trial of Combined Weekly Bortezomib and Tositumomab I-131 in Patients With Relapsed or Refractory Follicular Non-Hodgkin's Lymphoma

Follicular Lymphoma

United States
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of [14C]AZD9977 in Healthy Male Subjects

Cardiovascular Disease

United Kingdom
Medical University of Vienna

Unknown

Lipid and Glycogen Metabolism in Patients With Impaired Glucose Tolerance and Calcium Sensing Receptor Mutations (RISC_7T)

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus | Healthy Volunteers | Prediabetes (Insulin Resistance, Impaired Glucose Tolerance) | Familiar Hypocalcuric Hypercalcemia

Austria
University of Southern California
Agency for Healthcare Research and Quality (AHRQ); Teladoc Health

Completed

Improving Safe Antibiotic Prescribing in Telehealth

Acute Respiratory Infection | Telehealth

United States
Wuhan Union Hospital, China

Recruiting

The Diagnostic Value of Hybrid PET/MR for Systemic Amyloidosis

PET/MR | Systemic Amyloidosis

China
Galapagos NV

Completed

A Study in Healthy Male Volunteers to Test How the Test Medicine GLPG1972 is Taken up by the Body When Given by Mouth and Into the Vein as an Injection

Healthy

United Kingdom
GlaxoSmithKline

Completed

Retreatment of Patients With Non-Hodgkin's Lymphoma Who Have Previously Responded to Iodine-131 Anti B1 Antibody

Lymphoma, Non-Hodgkin
National Institute of Mental Health (NIMH)

Recruiting

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

Parkinson's Disease | Dementia | ALS | Alzheimer's Disease

United States
GlaxoSmithKline

Completed

Study of Safety and Efficacy of a Sequential Regimen Consisting of Three Cycles of Fludarabine Followed by Tositumomab and Iodine I 131 Tositumomab

Lymphoma, Non-Hodgkin
GlaxoSmithKline

Completed

Pivotal Study of Iodine I 131 Tositumomab for Chemotherapy-refractory Low-grade or Transformed Low-grade B-cell Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin
GlaxoSmithKline

Withdrawn

A Comparative Study Of Iodine I 131 Tositumomab Therapeutic Regimen Versus Ibritumomab Tiuxetan Therapeutic Regimen

Lymphoma, Follicular | Lymphoma, Non-Hodgkin | Lymphoma, Small Cleaved-Cell, Follicular | Lymphoma, Large-Cell, Follicular

United States
Emory University

Completed

Norepinephrine Transporter Availability in PTSD

Posttraumatic Stress Disorder

United States
University of Colorado, Denver

Terminated

Transplacental Gradients and Transport in Intrauterine Growth Restricted (IUGR) Pregnancies Compared to Normal Pregnancies.

Pregnancy | IUGR

United States
Gilead Sciences
Nimbus Apollo

Completed

Study to Evaluate the Pharmacodynamic Effects of a Single Oral Dose of GS-0976 (NDI-010976) in Healthy Adult Subjects

PD Effects of GS-0976 (NDI-010976) on Fractional DNL

United States
Theravance Biopharma
GlaxoSmithKline; Hammersmith Medicines Research

Completed

A Phase 1 (Ph1), Single Dose (SD), GSK961081 Absorption, Distribution, Metabolism, and Excretion (ADME) Study in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Withdrawn

Concurrent PET D2/D3 Receptor Imaging and fMRI Smoking Cue Reactivity in Smokers

Nicotine Dependence | Smoking Cue Reactivity | Relapse to Smoking

United States
Landos Biopharma Inc.

Recruiting

Study to Evaluate the Clinical Activity and Safety of Oral NX-13 in Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Belgium, Italy, Poland
Cancer Trials Ireland

Completed

Spinal Cord Compression Re-Treat Study

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Radiation Toxicity | Spinal Cord Compression

Ireland
Karolinska University Hospital
University of Copenhagen

Completed

Postoperative Neuroinflammation and Cognitive Dysfunction After Abdominal Surgery (POPE)

Surgery | Anesthesia | Neurogenic Inflammation | Cognitive Disorders
Anthera Pharmaceuticals

Completed

Liprotamase Efficacy Trial in Patients With Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency (DIGEST)

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Anthera Pharmaceuticals
Cystic Fibrosis Foundation

Completed

Oral TheraCLEC™ - Total in Cystic Fibrosis Subjects With Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Pancreatic Insufficiency

United States

Search clinical trials for: Pyruvate (13C)

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