Search clinical trials for: RO4917523 0.5 mg

Total 15044 results

Meshalkin Research Institute of Pathology of Circulation

Completed

The Efficacy and Safety of Hypertonic Saline in Cardiac Surgery Patients. (ESHHS)

Coronary Artery Disease | Edema

Russian Federation
Virginia Commonwealth University

Withdrawn

Pharmacokinetic Profile and Dermatomal Coverage of the Erector Spinae Plane Block

Pain, Postoperative | Pain, Chest

United States
Acerus Pharmaceuticals Corporation

Completed

Efficacy of an Intranasal Testosterone Product

Hypogonadism

United States
United Therapeutics

Withdrawn

FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, Australia, Mexico
Quark Pharmaceuticals
Pfizer

Completed

Phase II Open Label Multicenter Study For Age Related Macular Degeneration Comparing PF-04523655 Versus Lucentis In The Treatment Of Subjects With CNV (MONET Study). (MONET)

Age Related Macular Degeneration

Spain, Korea, Republic of, Turkey, Taiwan, United States, Israel, Austria, Philippines, Denmark, Hong Kong, India
Pfizer

Terminated

Study Evaluating Single Dose Of ILV-095 In Psoriasis Subjects

Plaque Psoriasis

United States, Canada
Ferring Pharmaceuticals

Completed

Exploratory Study Assessing Synchronisation of Egg Sacs With Degarelix

Infertility, Female

Belgium, Czech Republic, Spain
AstraZeneca
Parexel

Completed

A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual Component Co-administration.

Type 2 Diabetes Mellitus

United States
Adapt Produtos Oftalmológicos Ltda.

Withdrawn

Antibiotic Steroid Combination Compared With Individual Administration in the in the Treatment of Ocular Inflammation and Infection

Ocular Inflammation | Keratitis | Conjunctivitis, Bacterial | Infection Associated Blepharitis

Brazil
Alexza Pharmaceuticals, Inc.
PPD

Completed

Staccato Prochlorperazine Single Dose PK Study

Migraine

United States
Region Skane

Completed

Vaccination in Inflammatory Rheumatic Disease (VACCIMIL). The Impact of Antirheumatic Treatment on Antibody Response (Vaccimil)

Syndrome | Vasculitis | SLE | Scleroderma | RA | Sjögrens

Sweden
Pfizer

Completed

Pharmacokinetic And Pharmacodynamic Study Of A Single-Dose Of PF-04950615 (RN316) In Combination With Atorvastatin

Dyslipidemia | Hypercholesterolemia

United States
University Hospital, Ghent

Completed

What is the Influence of a Different Thread Pitch Design on Bone Remodelling Around Conical Southern Oral Implants?

Dental Implants

Belgium
Arcutis Biotherapeutics, Inc.

Active, not recruiting

Open Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-OLE)

Atopic Dermatitis Eczema

United States, Canada
Caroline Rickards

Completed

Pulsatile Perfusion Therapy Phase II (PPT2)

Hemorrhage

United States
Rigel Pharmaceuticals

Completed

To Assess the Safety and Efficacy of R932348 Ophthalmic Solutions in Patients With Keratoconjunctivitis Sicca (DROPS)

Keratoconjunctivitis Sicca

United States
Opthea Limited

Recruiting

OPT-302 With Ranibizumab in Neovascular Age-related Macular Degeneration (nAMD) (ShORe)

Neovascular Age-related Macular Degeneration

United States, Argentina, Australia, Brazil, Bulgaria, Canada, Colombia, Czechia, Denmark, France, Germany, Greece, Hungary, India, Israel, Italy, Korea, Republic of, Latvia, Malaysia, Poland, Spain, Thailand, Ukraine, United Kingdom
Celgene

Withdrawn

A Phase 2 Study With CC-220 in Skin Sarcoidosis

Sarcoidosis
St. Petersburg Research Institute of Vaccines and...

Completed

Trial of Tolerability, Safety and Immunogenicity of the Flu-M Vaccine in Children Between 6 Months and 9 Years Old

Influenza, Human | Vaccination; Infection | Vaccines

Russian Federation
Dr. Christoph Ilies

Completed

Ultrasound Guided Intercostobrachial Nerve Block

Anaesthesia

Germany
The Hospital for Sick Children

Completed

0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children

Hyponatremia

Canada
Xeris Pharmaceuticals
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Emissary...

Completed

Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of G-Pen(TM) (Glucagon Injection) to Treat Severe Hypoglycemia

Hypoglycemia

United States
Lawson Health Research Institute

Not yet recruiting

Perioperative Pain Management for Total Shoulder Arthroplasty: A Pilot Non-Inferiority Trial

Anesthesia, Local | Local Infiltration | Shoulder Arthritis

Canada
HonorHealth Research Institute
Incyte Corporation

Withdrawn

Pemigatinib in Subjects With Adenosquamous Carcinoma of the Pancreas

Pancreas Cancer

United States
Pfizer

Completed

Multiple Intravenous Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

Japan
Takeda

Withdrawn

A Phase 1, Single and Multiple Dose Study of TAK-137

Healthy Japanese Adult Male

Japan
Peking University First Hospital

Unknown

A Study in Reversing Hepatic Fibrosis or Cirrhosis Related to Hepatitis B Virus and Finding Biomarkers

Hepatitis B | Liver Fibrosis

China
Ardea Biosciences, Inc.

Completed

RDEA3170 Bioavailability Study

Gout

United States
AstraZeneca

Completed

Bioequivalence Study of Combination Tablets of Saxagliptin / Dapagliflozin / Metformin XR (Extended-release) and Dapagliflozin / Metformin XR Relative to Individual Components in Healthy Subjects

Type 2 Diabetes Mellitus

United Kingdom
University of Saskatchewan
Canadian Institutes of Health Research (CIHR)

Completed

Human Ovarian Follicular Dynamics and Emergency Contraception

Contraception

Canada
Dr Manar Mamdouh Fahmy Elsharkawi

Completed

A Comparison of Postoperative Outcomes Provided by a Continuous Preperitoneal Infusion Versus Ultrasound Guided Rectus Sheath Block for Midline Emergency Laparotomy

Abdominal Pain
Ardea Biosciences, Inc.

Completed

RDEA3170 and Febuxostat Combination Study in Gout Subjects

Gout

United States
Arcutis Biotherapeutics, Inc.

Completed

Safety and Efficacy of ARQ-151 Cream in Adolescents and Adults With Atopic Dermatitis

Atopic Dermatitis

United States, Canada
Xiamen LP Pharmaceutical Co., Ltd

Completed

Buccal Film Versus IV Injection Palonosetron for Moderately Emetogenic Chemotherapy Induced Nausea and Vomiting

Nausea With Vomiting Chemotherapy-Induced

United States
Peptron, Inc.

Active, not recruiting

SR-Exenatide (PT320) to Eveluate Efficacy and Safety in Patients With Early Parkinson's Disease

Early Parkinson's Disease

Korea, Republic of
Idera Pharmaceuticals, Inc.

Completed

Extension Study of IMO-8400 in Patients With Waldenström's Macroglobulinemia Who Completed Study 8400-401

Waldenstrom's Macroglobulinemia
Centre hospitalier de l'Université de Montréal...

Completed

Efficacy of Propofol vs Placebo in the Prevention of Coughing During Emergence of General Anesthesia Under Desflurane (PROPOREV)

Coughing | Elective Surgery

Canada
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

Rivastigmine and Huperzine A as Treatments for Cocaine Dependence

Substance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
Warner Chilcott

Terminated

Efficacy & Safety of Single Dose Alprostadil Cream (2 Concentrations Enhancer) to Vehicle in Men w/Erectile Dysfunction

Erectile Dysfunction

United States
Darnitsa Pharmaceutical Company
International Pharmaceutical Research Center

Completed

Bioequivalence Study of 8 mg Perindopril Tert-butylamine / 2.5 mg Indapamide Tablets Versus 10 mg Perindopril Arginine / 2.5 mg Indapamide Film-coated Tablets in Healthy Volunteers

Healthy Subjects | Bioequivalence

Jordan
QED Therapeutics, Inc.

Enrolling by invitation

A Study to Evaluate the Efficacy and Safety of Infigratinib in Children and Adolescents With Achondroplasia (PROPEL3)

Achondroplasia

Australia, United States, Argentina, Canada, France, Germany, Italy, Norway, Singapore, Spain, United Kingdom
Alcon Research

Completed

Ocriplasmin for Vitreomacular Traction/Symptomatic Vitreomacular Adhesion

Vitreomacular Traction | Vitreomacular Adhesion

Australia
Aldeyra Therapeutics, Inc.

Completed

A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber

Conjunctivitis, Allergic

Canada
Stiefel, a GSK Company
GlaxoSmithKline

Completed

U0289-405: An Open-Label, 12-Week Study to Evaluate the Efficacy and Safety of the Acne System (Benzoyl Peroxide 2.5%, Salicylic Acid 0.5%) in Subjects With Acne

Acne Vulgaris

United States
Cara Therapeutics, Inc.

Completed

A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee

Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Alexion Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of SBC-102 (Sebelipase Alfa) in Adult Participants With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD) | LAL-Deficiency

France, United States, United Kingdom, Czechia
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Valsartan and Amlodipine in Patients With Essential Hypertension

Essential Hypertension

Japan
Forest Laboratories
Gedeon Richter Ltd.

Completed

Safety and Efficacy of Cariprazine As Adjunctive Therapy In Major Depressive Disorder

Major Depressive Disorder

United States
FORUM Pharmaceuticals Inc
Syneos Health

Completed

Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Alzheimer's Disease

Central Nervous System Diseases | Alzheimer's Disease

United States
AstraZeneca

Completed

A Single Dose PD & PK Study With Two Formulations of Abediterol in Patients With Asthma

Asthma

Germany

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